C-reactive protein ;is a type of protein produced by the liver in response to an infection ;or inflammation. When your body contracts an infection, the white blood cells produce proteins to fight it. Some of these proteins activate the liver into producing c-reactive protein. For many years, the crp ;blood level has been used to ascertain the level of infection or inflammation.

Assessing the risk of heart disease ;with c-reactive protein

The level of crp is a potential indicator of how likely you are to develop cardiovascular diseases. This is because the development of atherosclerosis is linked with inflammation within the walls of your blood vessel. This results in higher levels of c-reactive protein in atherosclerosis patients than in those without the disorder.

The greater the crp levels, the more chances you have of being affected by cardiovascular disorders. The test also determines the risk of a second attack.

The value of knowing your crp levels depends on whether you come under one of three cardiovascular risk groups.


	
	High risk   not important to know crp because you should be combining lifestyle changes and aggressive treatment to reduce risk
	
	
	Intermediate risk   helpful to find out crp levels, as it can provide vital information crucial in deciding the next line of treatment
	
	
	Low risk   even if your crp levels are high, you will not be at risk   due to negligible risk factors and low cholesterol levels   that should require more than just lifestyle changes
	


To find out crp levels you will have to take a blood test. C-reactive protein is classified into  


	
	High   equal to or greater than 3
	
	
	Intermediate   between 1 and 3
	
	
	Low   below 1
	


If you are having a c-reactive protein test to check for heart diseases, your healthcare provider may recommend a cholesterol test as well. A number of other tests may also be prescribed to evaluate your risk further.

How C-reactive Protein Can Pose A Risk For Heart Disease?

Abstract

Background: it is essential to have an understanding of life expectancy and risk factors among patients with sickle cell disease (sickle cell anemia, hemoglobin diseases, and thalassemias). These are required to counsel the patients, target treatment, and plan the right clinical trials.

 

Methods: a research followed 3764 people ranging from birth to 66 years of age and suffering from scd. The procedure was done to understand the life expectancy and calculate the average age at death. Moreover, the study understood the reasons for the death in all 209 adults. It used the proportional-hazards regression analysis to know the risks for an untimely death in adults with sickle cell anemia.

 ;

Results: when the results for young kids and adults with sickle cell anemia were observed, it was found that the average age at death was 48 for women and 42 for men. Moreover, suffering from hemoglobin c disease had an average mortality age of 60 for men and 68 years for women.

 

In people with sickle cell disease, 18% of deaths took place in patients with mainly renal organ failures. 33% of the tested patients were medically free of organ failures but episodes of pain crisis took their life. Out of these patients, 78% experienced chronic pain, chest syndrome, or both, while 22% suffered a stroke that took their lives.

 ;

Clinical modeling showed that people with sickle cell anemia faced acute chest syndrome, seizures, kidney failure, a white-cell count of over 15, 000 per cubic mm, and a low hemoglobin level were related to a risk of early death.

 

Conclusions: results suggested that 50% of patients with sickle cell anemia lived beyond the age of 50. A huge share of those who lost their lives suffered no noticeable chronic organ failure. However, most of them died due to acute episodes of pain or stroke. Early death was seen highest among patients who had symptomatic disease. High levels of fetal hemoglobin suggested improved chances of survival and are assumably a credible source to foresee the risks and other factors related to adult life expectancy.


 ;

Life Expectancy And Risk Factors Involved In Sickle Cell Disease

Your body needs some cholesterol to produce hormones and vitamins that help in digestion. Two types of lipoproteins   ldl cholesterol and hdl cholesterol   are responsible for carrying cholesterol to and from the cells in your body.

Hdl or high-density cholesterol is good cholesterol. It carries bad cholesterol away from the arteries and other body parts back to the liver to be processed by the liver.

Ldl or low-density cholesterol, also known as the bad cholesterol, contributes to fatty build-ups within the arteries. This results in narrowing of the arteries and increases your risk of cardiovascular diseases like pad, heart attack, or even stroke.

Although there are medications to bring down ldl cholesterol levels, your doctor may recommend using therapeutic lifestyle changes to see how well your cholesterol levels can be managed without medications.

How to reduce  bad  cholesterol naturally

You can lower ldl cholesterol levels naturally with the following measures  

Diet and weight loss

Being obese or overweight not only increases the odds of developing high ldl levels but also contributes to cardiac diseases and chronic conditions. Studies suggest that losing even a little weight may help reduce ldl levels.

Your diet plays an important role in losing excess fat and maintaining ideal body weight. Eating the right kind of food   such as those that contain a good amount of monosaturated fats, phytosterols and soluble fibre   can help lower harmful ldl cholesterol and increase the levels of hdl cholesterol in the blood. Focus on eating whole grains, fruits and leafy vegetables, legumes, nuts and seeds, and fatty fish.

Exercise more often

Exercising regularly, in moderate amounts, can bring down your cholesterol levels and promote weight loss. Any form of cardiovascular activity, such as cycling, running, swimming and jogging benefits your heart health. You may also turn to other forms of exercise   weight training or yoga   as they also work to decrease the levels of bad cholesterol.

Quit smoking

Smoking causes a number of chemical changes in your body. Cigarette smoke increases bad cholesterol (ldl) and triglycerides levels. This leads to the accumulation of waxy plaque, which clogs the arteries. At the same time, smoking reduces the level of good cholesterol   the one that prevents the formation of plaque in your blood. Quit smoking and turn to a healthier lifestyle to see a difference in the levels of your ldl cholesterol.

Limit alcohol consumption

According to studies, heavy alcohol consumption or drinking more than what is considered moderate significantly increases bad cholesterol, which again raises triglyceride levels and ldl cholesterol.

Lifestyle changes are the natural and first line of treatment for people with high cholesterol levels. However, if your doctor suspects these levels could put you at risk of other medical conditions, he/she might recommend medications to manage bad cholesterol.

Reduce LDL Cholesterol With These Easy Steps

As the name suggests, kidney cancer, also known as renal cancer, starts in the kidneys. It occurs when the healthy kidney cells grow out of control and become malignant to form cancerous tumours. ;Renal cell carcinoma is the most common type of cancer affecting the kidneys  here cancer begins in the lining of the tubes of your kidney.

Risk factors of kidney cancer

The exact cause of kidney cancer is not known. However, studies suggest that certain factors can make you susceptible to renal cancer. These include  


	
	Smoking
	
	
	Overuse of certain medications
	
	
	Excessive body weight
	
	
	Genes/heredity
	
	
	Gender   men rather than women are prone to kidney cancer
	
	
	An underlying health condition, such as ;high blood pressure
	


Early signs of kidney cancer

The symptoms of renal or kidney cancer depend on its types. In most cases, the disease does not exhibit noticeable symptoms in its early stages. This makes the diagnosis of cancer difficult. However, the signs become more apparent and observable as cancer starts to metastasize. You should watch out for these signs of kidney cancer -


	
	Bouts of blood in the urine   a condition commonly known as haematuria
	
	
	Pain on one side of the lower back (near the kidneys)
	
	
	A lump or mass on the lower back or side, where your kidneys are located
	
	
	Loss of appetite
	
	
	Tiredness or ;fatigue
	
	
	Unintentional weight loss
	
	
	Fever ;that does not cure in days
	
	
	Anaemia   low count of the red blood cells
	
	
	In men, a cluster of enlarged veins called varicocele may develop around the testicles (particularly around the right testicle), indicating the presence of a large tumour
	


Often, these symptoms are mistaken for those of other conditions or diseases. Therefore, it is important to consult a specialist.

If you encounter the above symptoms, or if you are concerned about any changes that you have been experiencing lately, talk to your healthcare provider. A doctor will enquire about the symptoms and might ask you questions related to these signs   how long have you been experiencing them, or how severe is the pain etc. This is crucial for early diagnosis and treatment of kidney cancer.

Know How To Detect Kidney Cancer Early

The moment you are diagnosed with a tumour, the first thing your doctor will do is find out whether the tumour is benign or malignant   this will determine the course of your treatment. In simple words, benign means non-cancerous while malignant means cancerous.

Benign cancer

When tumour cells grow at a normal pace, it is known as benign or non-cancerous growth. In the case of benign cancer, the cells grow slowly and do not spread to other parts of the body or invade the adjacent tissues. Most often, these do not exhibit serious symptoms or pose a threat to your health. So, they are not a cause of concern. However, sometimes a benign tumour can press against nerves, tissues or the blood vessels, causing pain and discomfort.

Some common types of benign cancer are  


	
	Adenomas
	
	
	Fibromas or fibroids
	
	
	Hemangiomas
	
	
	Lipomas
	


Benign tumours, although tend to be harmless, may need to be operated. This is true for tumours that have grown to become large and weigh heavy. When these develop in the brain and cluster around to press against block channels or vital organs, the condition can be potentially dangerous. Moreover, certain types of non-cancerous tumours like intestinal polyps are precancerous   meaning they have the potential to turn cancerous. ;Surgery to remove this type of tumour can help prevent it from becoming malignant.

Malignant cancer

Malignant cancer refers to cancerous tumours that can potentially be fatal. Unlike benign cancer, malignant cancer progresses quickly and metastasizes to invade other organs, tissues or parts of the body.

Here are a few examples of tumours that are cancerous in nature  


	
	Carcinoma
	
	
	Sarcoma
	
	
	Germ cell tumour
	
	
	Blastoma
	


A tumour that has turned malignant, or has spread through the lymphatic system or bloodstream, may require aggressive treatment. Based on the stage of cancer, your ;oncologist will devise a treatment plan that might include immunotherapy, ;radiation therapy, chemotherapy ;or surgery.

Being diagnosed with a tumour can be hard to deal with. To find out if the tumour is benign or malignant, consult a specialist and discuss your concerns.

Benign Cancer Vs Malignant Cancer: Know The Difference!

Preeclampsia is a condition that affects women during pregnancy. It is characterized by increased blood pressure and high levels of protein in the urine. Women with preeclampsia also experience swelling in the feet, legs, and arms.

Researchers suspect that excessive body fat or poor nutrition are the primary contributors to preeclampsia and eclampsia.

If left undetected, preeclampsia can lead to a more severe complication, known as eclampsia. Eclampsia can put you and your baby at risk, and can even lead to death (in rare cases).

How do preeclampsia and eclampsia affect the mother?

Preeclampsia and eclampsia can cause a host of complications for the mother, such as the following  

Hellp syndrome   hellp syndrome refers to three different conditions   low platelet count, elevated liver enzymes, and haemolysis. This generally occurs late in pregnancy and affects the processing of rbc, functioning of the liver, and blood clotting.

Seizures

Heart and renal failure

Water in the lungs

Bleeding from the liver

Reversible blindness

Effects of preeclampsia and eclampsia on the baby

Preeclampsia can lead to problems with the placenta in the initial stage of pregnancy. This may pose risks, including the following to the baby  

Lack of nutrients and oxygen, which may prevent the foetus to grow properly

Preterm birth

Stillbirth   this happens when the placenta is separated from the uterine wall

Infant death

Stillbirths are more common when the mother has suffered from a severe form of preeclampsia, like hellp syndrome.

Preeclampsia and eclampsia are linked to a myriad of health issues and life-long challenges for prematurely born babies. These may include cerebral palsy, learning disorders, epilepsy, deafness and blindness.

There is no particular cure for preeclampsia and eclampsia. Treatment, however, depends on how close you are to your due date, and how much the foetus has developed. In the case of mild preeclampsia, your doctor may recommend resting, healthy eating   that limits salt intake   and regular prenatal checkups.

Effects Of Preeclampsia And Eclampsia On You And The Baby

Don't wait any longer, manage your Microbiologist online with a Lybrate doctor today

Consult for Microbiologist - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES