Blood is one of the most crucial elements of human existence. It works as a commute for oxygen and various nutrients in reaching the cells. These functions make blood a vital source for the body to operate. That said, india needs 38, 000 blood donations every day, which adds up to 5 crore units required in a year. However, only 2.5 crore units are available against the huge unfulfilled numbers. Hence, it is essential to recognize the importance of blood donation.

 

Why is blood donation important?

While blood donations are essential to help people with surgeries, they are equally vital during cancer treatments, chronic diseases, and gruesome injuries. Moreover, they also benefit the donors in a significant way.

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Types of blood donations

Blood donations are of several types through which a single donor has the potential to help nearly three people.

 

Whole blood donation

It is the most common process of donating blood. One pint of blood collected supports numerous patients in the process. It is, then, divided into different components that aid the donation.

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Plasma donation

The process of plasma collection is carried out through a method called apheresis. It divides plasma from other blood components. Its blood clotting abilities help trauma patients and people undergoing cancer treatment.

 

Platelet donation

The collection of platelets is also done using apheresis. Once identified in the donor s blood, the rbcs and the donor gets other fluids back. Cancer patients are the chief beneficiaries of platelets as they play a prominent role during cancer treatments.

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Double red cell donation

Red blood cells are also collected through the apheresis process. It helps donors to donate twice the dose of a whole blood donation. One can help a patient suffering from blood loss using this method.

 

Advantages of blood donation

Blood donations have several advantages that people should know. They help fight many severe health conditions in the human body. Some of them include-


	
	Loss of blood due to internal or external injuries caused by accidents
	
	
	Sickle cell disease or other abnormalities that affect the blood
	
	
	In the treatment of cancer
	
	
	Cardiovascular or orthopedic surgeries
	
	
	Blood disorders
	
	
	Transplant processes
	
	
	Treatments involving plasma
	


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Covid-19

According to food and drug administration (fda) reports, patients who have recovered from covid-19 can help others by donating blood plasma. They contain antibodies that fight the infection, helping their body fight the virus.

 

Benefits for the donor

Even the donors receive many health and social benefits because of blood donation. Where donated blood saves lives, experts suggest that donors can also benefit from the same. Some of these advantages include:

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	Boosting cardiovascular health
	
	
	Maintaining blood pressure
	
	
	Contributing to the community
	
	
	Reducing the iron levels
	
	
	Improving overall health
	



 

Why Blood Donation Is Important?

Cushing syndrome occurs due to prolonged exposure to high levels of cortisol hormone. The condition, often referred to as hypercortisolism, affects women   usually between ages 25 and 40   more than men. Nearly 80% of adults and about 47% of children are diagnosed with cushing syndrome.

The most common cause of cushing syndrome is an overproduction of the stress hormone   cortisol   by the adrenal glands. However, it can also result from overuse of steroid drugs.

If you have cushing syndrome, you are likely to notice symptoms like muscle weakness, weight gain, a buffalo lump, irregular periods, sleep disorders, high blood glucose and high blood pressure.

Recent research has claimed to establish a relation between cushing syndrome and high blood pressure   or what is called hypertension in medical terms.

The link between hypertension and cushing syndrome

Hypertension refers to high blood pressure that causes the force of blood to raise against the artery walls. A number of conditions can lead to hypertension, such as poor diet and lifestyle, an underlying health issue, stress, pregnancy and so on.

As your body encounters stress, the adrenal glands produce and release cortisol in the bloodstream. Studies show that producing excess stress hormone can create a host of pathological problems in the body, including hypertension.

Hypertension is a distinguishing feature of endogenous cushing syndrome. High blood pressure in cushing syndrome has a significant correlation with the duration of hypercortisolism and results from the interaction between various pathophysiological methods regulating peripheral vascular resistance, cardiac output, and plasma volume   all of which are elevated in this state.

How to treat the condition

Cushing syndrome is usually treatable and curable. You will be prescribed to stop using steroid drugs that are likely to increase cortisol levels. If the condition does not improve after treatment, you will have to look for ways to manage the symptoms, especially by monitoring your blood pressure. Team up with your doctor and ask for ways to de-stress yourself.

Relation Between Cushing Syndrome And Hypertension: Know More

What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

The most common forms of diabetes ;are type 1 and type 2 diabetes. In type 1, your immune system damages the cells inside the pancreas that produce insulin. Therefore, the pancreas are unable to produce an adequate amount of insulin.

In type 2 diabetes, your body does not respond properly to the insulin produced by the pancreas. As a result, your body will have a difficult time removing sugar ;from the blood. The cells may stop insulin production over time that may lead to insulin deficiency. However, there are other forms of diabetes that are lesser-known but can affect you just as bad.

Types of diabetes beyond type 1 and type 2

Gestational diabetes

In gestation diabetes, a condition that affects pregnant women, the blood sugar levels increase to an extent that may hamper the health of the mother and the child.

Symptoms

Usually, there are no symptoms as such. If diabetes worsens, women may observe symptoms such as -


	
	A need to pee more frequently
	
	
	Excessive thirst and hunger
	
	
	Dryness in the mouth
	


Lada (latent autoimmune diabetes in adults)

It is sometimes referred to as type 1.5 diabetes. Here, your immune system kills the insulin-producing cells inside the pancreas. As this condition takes a longer period to develop, you may not need insulin for many months after you have been diagnosed.

Symptoms

You may observe the following symptoms  


	
	Dryness and itchiness
	
	
	Tingling sensation in feet or hands
	
	
	Blurry vision
	
	
	Frequent urination
	


Mody (maturity-onset diabetes of the young)

This condition is observed during adolescence. Here, genetic mutations limit the pancreas from making insulin. So, due to insufficient insulin, your blood sugar level goes up. If any of your parents have mody, you are likely to have the condition.

Symptoms

Symptoms may include  


	
	Yeast and ;skin infections
	
	
	Frequent urination
	
	
	An urge to pee more often
	


Treatment

Primary care for these other forms of diabetes follows the usual course of treatment as with type 1 and type 2.


	
	Diabetic medications
	
	
	Insulin shots or injections
	
	
	Dietary changes
	


The doctor may instruct you to monitor your blood sugar levels frequently to keep it under control. This will be accompanied by a diet ;consisting of adequate calories, but avoid fatty foods, excess sugar and carbohydrates. Mild exercise is also recommended.

The best way to prevent these conditions is to visit your doctor frequently and follow the treatment plan. Do not keep your diabetes untreated.

A Sneak Peek Beyond Type 1 And Type 2 Diabetes

Potassium is one of the seven essential macrominerals found in a variety of foods, including legumes, fish, and leafy vegetables. The mineral plays a vital role in various body functions, such as regulating water balance, heart functioning, and muscle contractions.

Potassium deficiency can lead to weakness, ;fatigue, and constipation. It is therefore important that you include potassium-rich foods in your daily ;diet.

However, keep in mind that taking in more than the required amount of potassium can do more harm than good to your body.

How much should you take in and why?

As per the world health organization, the recommended daily intake of potassium for adults is between 3500mg and 4700mg, as it is safe to consume. When taken in recommended measures, a potassium-rich diet can have some impressive benefits on your overall health. It may reduce or prevent a host of health problems.


	
	Lower high blood pressure
	
	
	Helps eliminate salt insensitivity
	
	
	Reduces your chances of getting a ;stroke by 7%
	
	
	Helps prevent osteoporosis and minimizes the risk of bone fractures
	
	
	Alleviates the risk of ;kidney stones
	


Natural foods are the best source of this mineral. However, you may also turn to supplements, as per your healthcare provider s recommendation.

How much is too much?

Despite its health benefits, potassium should be consumed within the prescribed limit. Going overboard can cause excess potassium to be stored in your blood, and your kidneys may not be able to filter the excess amount   this condition could possibly lead to hyperkalemia. If your potassium levels are between 5.1mmol/l and 6.0mmol/l, you might be at risk of hyperkalemia. Higher than 6.0mmol/l level is considered dangerous   you will need to monitor and manage the condition in order to avoid the risk.

Potassium is essential for bodily functions. A healthy diet and overall eating patterns are important for maintaining good health and keeping illnesses at bay. Be sure to meet your recommended daily intake and avoid exceeding 4700mg of potassium daily. If you are looking to include supplements, talk to your doctor and make sure you stick to the prescribed dosage.

How Safe Is Potassium For Your Health?

Hepatitis- related to an inflammatory condition of the liver. It occurs mainly due to infection caused by viruses but there are other possible causes as well. Hepatitis can be temporary or viral. Temporary hepatitis, which is acute in nature, gets resolved on its own. Viral hepatitis can be of five types, a, b, c, d, and e.

Symptoms of hepatitis

Hepatitis, in its initial phase, is called the acute phase. The following symptoms along with mild flu are visible:

Loss of appetite
Fatigue
Joint pains
Pain in the abdomen
Nausea
Weight loss
Jaundice
Though this phase is not really dangerous for some patients, it can result in liver failure leading to death.

How is hepatitis diagnosed?

Physical examination
Laboratory tests
Imaging tests


Treatment for hepatitis

Treatment options for different types of hepatitis are:

Hepatitis a: this doesn t require treatment as it is short-term in nature. In case the symptoms cause a lot of discomforts, then bed rest is recommended. The vaccine is available to prevent this infection.

Hepatitis b: acute hepatitis b doesn t require treatment either. Its chronic form can be treated with antiviral medications. This can be prevented with vaccination.

Hepatitis c: this type of hepatitis, both in its acute and chronic forms, is treated through antiviral medications.

Hepatitis d: according to a study in 2013, a drug known as alpha interferon is used to treat this type of hepatitis. Unfortunately, this only comes to the rescue of 25-30% of people.

Hepatitis e: this acute form of hepatitis gets resolved on its own. Adequate rest, drinking a sufficient amount of water, and taking enough nutrients in their food are some of the ways to get healed from this disease.


 

Hepatitis: Signs, Diagnosis, And Treatment

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