The skin is an elastic organ (yes, it is an organ!), but only to a certain extent. It has a limit to which it can accommodate the underlying tissues. With the increase in bulk, for example, puberty, pregnancy, muscle mass building or surgical implants, the skin is made to stretch beyond its limits. What happens is this stretch causes the skin to stretch too, and these stretch marks or striae become an unpleasant thing that needs to be hidden. 

Dressing needs to be changed so that they are not showing. Dermatologists see a big demand for getting rid of these marks too. There have been conventional, time-tested methods which help in getting rid of these. However, with newer advancements in dermatology, the platelet rich plasma is being widely used for getting rid of these stretch marks.

Why stretch marks? 

In any of the scenarios above, the stretch marks appear because there is a lack of underlying supportive tissue when it is stretched out. There is a lack of collagen and connective tissue, causing stretch marks. These are most evident in fat collecting areas like breasts, abdomen, thighs, upper arms, etc.

What is platelet-rich plasma or PRP? 

The blood is composed of a liquid portion known as plasma, which contains three main types of cells i.e. white blood cells, red blood cells, and platelets. The white blood cells are the ones responsible for fighting infections. The red cells give blood its color and also are responsible for carrying nutrients to the various organs. The platelets are tiny fragments of cells which help in blood clotting. Platelets are also rich in what are called totipotent cells, which can grow into any type of cells. When the body is affected, due to injury, infection, trauma, etc., these get concentrated in the affected area and are produced in large numbers to help in the recovery of the particular affected area.

Technique: 

The area to be treated is isolated and prepared. Blood is centrifuged to remove other cells and obtain platelet rich plasma. This RPR is injected into the underlying layers of the skin. This induces the release of growth factors into the connective tissue space. Collagen is produced over a period of time, which causes the skin to become taut and lose the stretch marks. The injection can be repeated if required on the topmost layer. It can also be mixed with thrombin to form a gel, which is then used similarly. Using it both in the underlying and superficial layers helps in completely getting rid of the marks.

Studies have shown a reduction in both the depth and size of the stretch marks and some might require two to three repeat injections.


Stretch Marks - How PRP Therapy Can Help You?

Alzheimer's disease is a dynamic disease that causes loss of memory and other vital mental functions. To start with, someone with Alzheimer's disease may witness light confusion in the beginning and trouble recalling. In the long run, individuals with the disease may even overlook important individuals in their lives and experience emotional identity changes.

Dementia: Alzheimer s disease is the most widely recognised reason for dementia   a gathering of brain issues that causes the loss of intellectual and social abilities. In Alzheimer's disease, the brain cells deteriorate and die, bringing on an enduring decrease in memory and mental capacity.
Brain Cells: Despite the fact that the reasons for Alzheimer's is not yet completely comprehended, its impact on the brain is clear. Alzheimer's disease harms the brain cells. A mind influenced by Alzheimer's has fewer cells and fewer associations among surviving cells than a solid mind.
Brain Shrinkage: As more brain cells start to die, Alzheimer's prompts critical brain shrinkage. At the point when specialists inspect Alzheimer's brain tissue under the magnifying instrument, they see two sorts of irregularities that are considered to cause Alzheimer s. These are:
Plaque: These clusters of a protein called beta-amyloid may harm and crush brain cells in a few ways, meddling with cell-to-cell functioning. In spite of the fact that a definitive reason for brain cell passing in Alzheimer's is not known, the accumulation of beta-amyloid on the outside of brain cells is a prime reason.
Tangles: Brain cells rely upon an inner support and transport framework to carry the supplements and other fundamental materials through their long extensions. This framework requires the typical structure and working of a protein called tau. In Alzheimer's, strings of tau protein turn into strange tangles inside the brain cells. This may also cause the decrease of brain cells. 
Here are some more causes that can lead to this disease:

Age: Age is a most critical cause in the development of Alzheimer's disease. The probability of building up the condition increases after you reach sixty-five years of age.
Family history: The qualities you acquire from your parents can add to your danger of building up Alzheimer's infection. This may also contribute to the environmental factors which can cause this condition. In some families, a single gene creates Alzheimer s disease and the dangers of the condition being passed on are much higher.
Head injuries: Individuals who have had serious head damage have been observed to be at higher risk of building up Alzheimer's disease.
Cardiovascular diseases: Research demonstrates that few lifestyle components and conditions connected with cardiovascular disease can build the danger of Alzheimer's disease. These include smoking, obesity, diabetes, hypertension and high cholesterol.


Alzheimer's Disease - Reasons That Can Lead To It!

Alzheimer s disease is a neurological, irreversible, progressive brain disorder. It is a chronic neurodegenerative dementia that causes the death of brain cells, causing memory loss and cognitive decline. It affects a person s thinking and behavior. The symptoms develop slowly and get worse as time passes.

Causes:
As it is a kind of dementia, Alzheimer s is caused by the death of brain cells. Over a course of time, brain cells die progressively and at the end, the tissue is left with fewer nerve cells and connections. As a result, the total brain size shrinks. Tiny inclusions called plaques and tangles can be seen in the postmortem. These cannot be seen or tested in a living Alzheimer s affected brain. These plaques are given the name  amyloid plaques  because they are found among the dying cells of the brain when a protein called beta-amyloid builds. The tangles stay in the neurons; they are formed from a protein called tau.

There are several reasons behind all this, some of which are listed below-

Anti-anxiety medications
Hitting on the head too many times
Regularly sleep-deprived
Loneliness
Diabetes in the brain
Old age
Genetic line
Down s syndrome
Cardiovascular diseases
Symptoms:
Alzheimer s disease damages the brain, so the clinical signs and symptoms begin to show very early. The symptoms are-

Memory loss
Agitation and mood swings
Poor judgment
The trouble with money calculations
Difficulty doing familiar tasks
Trouble in planning or solving a problem
Confusion with time and place
Difficulty in communicating
Loss of motivation
Inappropriate behavior
Aggressive personality
Childlike behavior
Preventing Alzheimer s disease:
Alzheimer s disease ultimately results in death. Even if there are treatments, they cannot fully cure it. So it s better to try to prevent it before it happens. Ways to prevent Alzheimer s disease are-

Eating more fruits and vegetables.
Eating berries every day.
Increasing omega-3 fatty acids.
Taking folic acid supplements.
Drinking grape juice or red wine with evening meal.
Doing the Mediterranean style diet.
Controlling the blood pressure.
Having strong social support.
Treatment of Alzheimer s disease:

Treatment of Alzheimer s disease is a long time process.
First of all, doctors perform a physical exam to check the overall neurological health. By this, they check muscle strength, reflexes, walking ability, sense of sight and hearing, coordination and balance.
Then comes the blood test to find the cause of confusion and memory loss by checking the thyroid disorder and vitamin deficiency.
Then they perform the neuropsychological test and check the mental status.
Then there are other tests, like MRI, CT, and PET.
After all this, drugs are given and a safe and supportive environment is created with proper exercise and nutrition.
Alzheimer s disease is undoubtedly the worst kind of disease. Hence, it is highly recommended to contact a doctor as soon as any symptom is noticed.

All About Alzheimer's Disease!

Ageing is inevitable, and as much as we want to escape, there is no way out. All organs, whether obvious or not, undergo gradual degeneration and deterioration. The brain is no exception, and memory being one of its main function also begins to decline with age. There are various factors which determine how quickly this ageing sets in and how rapidly it progresses. These are dictated by a person s lifestyle, activity levels, and overall body changes. Dementia also has a strong family history, and if you know someone who has a family history, there are some early signs that you could watch for. This will help in both empathizing with the person, as well as to help in arresting progression. Read on to know the signs that need to be watched out for.

Mood changes: Sudden changes in mood, especially going into short periods of depression without an obvious reason, is one of the first symptoms of dementia. If it is happening repeatedly, this can help identify dementia.
Personality changes: If a shy person suddenly becomes outgoing or vice versa, this could be an early indicator of dementia. They either develop or shed inhibitions, which is a new change for them.
Memory loss: Sudden short-term memory loss for a person who had a very strong memory is a definite indicator of dementia. They might clearly remember the distant events but forget small things like where to find their medicines, where things are in the kitchen or bathroom, etc. Because of this, you might see them repeating what they just did. This could be like washing a glass again, saying or asking the same thing again, etc.
The difficulty with regular tasks: Short-term memory loss causes difficulty with regular tasks like laying out the dinner table, finding regular medicines, paying utility bills, etc. There is also difficulty in learning new tasks, which further complicates things.
Feeling lost: Due to sudden memory loss and difficulty with regular tasks, they suddenly feel lost, which in turns adds to their depression.
Apathy: This also leads to a general lack of interest in things and people around them. They could have had hobbies, which no longer interest them.
Disoriented: They find it difficult to be aligned to time and space. Directions which they clearly know could seem difficult.
Not able to connect the dots: While the elderly people are generally good at telling stories and anecdotes, with dementia setting in, this becomes difficult.
These are some symptoms which can help identify if a near one is slowly developing dementia. Identifying in the early stages can help in arresting progress and extending support.

Dementia - How To Know If Someone Is Suffering From It?

Alzheimer's disease is a neurological problem that is characterised by a cognitive decline and memory loss. It is a type of neurodegenerative dementia. The symptoms of alzheimer's disease include not being able to absorb and retain new information, lack of reasoning and judging, not being able to take on complex tasks, impaired visuospatial abilities, problems in reading, writing and speech, among many others. If a person has at least two of these symptoms in a debilitating manner, then the diagnosis can be made in favour of alzheimer's disease. The main causes of alzheimer's are shrinkage of the brain size and death of the brain cells. The immune system is also said to trigger this neurodegenerative disease. Let us find out what medical science has found so far.

1. Connections: many a times, in alzheimer's disease, the memory and behaviour of the person changes because the brain is unable to make proper neural connections which can lead to memory loss of how a person behaved and the elements that formed the basis of the patient's cognition. Apparently, the immune system behaves in the same way within the brain and blocks the connection. This happens because there is constant communication between the brain and immune system along neurological lines, which is where the disease first emanates.

2. Inflammation: the brain is prone to inflammation or swelling that is not the normal kind. This inflammation happens as a result of the activation of the infection fighting neurotransmitters and the chemical changes that happen in the brain when an infection strikes. The inflammation usually happens in the plaques or clumps which the brain tries to protect. These clumps are made up of a protein called amyloid. The immune system is responsible for creating this inflammation in the brain of the patient.

3. Pattern recognition receptors: many of these receptors work in different manners and cooperate with each other to create a response in the brain. These prrs can be found in the brain plaques, and they develop the signs of danger which further fuels the inflammation in the brain as a matter of protection.

4. Activation of cells linked with the immune system: when the prrs begin to respond, it basically activates the immune system and the cells of the same. This is the basic reaction that causes the changes in brain which then leads to the attachment of the protein to the tissue that is diseased, in which case alzheimer's disease starts. The inflammation that we had spoken about earlier basically happens in the nervous tissue.

It is important to recognise and act on the initial signs of alzheimer's disease before it progresses beyond one's control.

Can the Immune System Trigger Alzheimer's Disease

One of the worst neurological disorders to have is dementia. It is a general term used to describe cognitive decline of the brain. It s not specific disease but denotes several brain disorders and mental illnesses. A person suffering from dementia can have severe impairment in judgment, loss of memory and thinking. Dementia is a very difficult disease not only for the patient but also for their families and caregivers. 

Some facts about dementia are as follows:

It s not a mental disorder occurring in old age but it does degenerates with age.
An estimation of 47.5 million people worldwide suffers from dementia and 60% of these people live in low and middle-income countries and according to WHO this figure is likely to increase.
Every 4 seconds a new case of dementia is reported
Dementia is a collective term to describe the many types of in people, such as 

Alzheimer s Disease: It is one of the most common type of dementia accounting for 60-80% of dementia case. People suffering from Alzheimer s have fewer nerve cells and the size of the brain shrinks.
Vascular Dementia: Another most common form of dementia occurring after a stroke.
Lewy Body Dementia: It is neurodegenerative condition that involves a protein called alpha-synuclein which changes the brain. Symptoms may be similar to Parkinson s disease.
Symptoms of dementia can range from mild to moderate to severe that includes:

Memory Loss
Disorientation meaning inability to focus or pay attention
Changes in visual perception
Impairment in reasoning and judgment
Dementia can be caused by damage to brain cells or progressive brain cell death. As a result communication between brain cells become difficult. Other symptoms include:

Stroke
Brain Tumor
Head Injury
Prion Disease
HIV Infection
Reversible Factors

There are no definite tests for dementia. Doctors and neurologists have to medical history, blood tests and CT scans to find out whether a person has dementia or not. However, the most potent evaluation comes from a set of questions that are asked to a patient suspected of having dementia. The ability to answer those questions correctly is one of the best diagnoses for dementia.
There is no specific treatment for dementia as it is not a curable disease and degenerates with time. However, medicines or drugs given for Alzheimer s can be given to people suffering from dementia.
Although results vary depending upon a person s lifestyle s and habits, doctors suggest eating healthy, exercising regularly, and stopping smoking and drinking may prevent some types of dementia.
The best treatment for dementia is to treat the person with care and love so that they don t feel neglected.
Dementia is often associated with old age but that is not always true. It is important to gain knowledge and educate others also.

Dementia - Quick Facts You Must Know About It!

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