Alzheimer's disease is a neurological problem that is characterised by a cognitive decline and memory loss. It is a type of neurodegenerative dementia. The symptoms of alzheimer's disease include not being able to absorb and retain new information, lack of reasoning and judging, not being able to take on complex tasks, impaired visuospatial abilities, problems in reading, writing and speech, among many others. If a person has at least two of these symptoms in a debilitating manner, then the diagnosis can be made in favour of alzheimer's disease. The main causes of alzheimer's are shrinkage of the brain size and death of the brain cells. The immune system is also said to trigger this neurodegenerative disease. Let us find out what medical science has found so far.

1. Connections: many a times, in alzheimer's disease, the memory and behaviour of the person changes because the brain is unable to make proper neural connections which can lead to memory loss of how a person behaved and the elements that formed the basis of the patient's cognition. Apparently, the immune system behaves in the same way within the brain and blocks the connection. This happens because there is constant communication between the brain and immune system along neurological lines, which is where the disease first emanates.

2. Inflammation: the brain is prone to inflammation or swelling that is not the normal kind. This inflammation happens as a result of the activation of the infection fighting neurotransmitters and the chemical changes that happen in the brain when an infection strikes. The inflammation usually happens in the plaques or clumps which the brain tries to protect. These clumps are made up of a protein called amyloid. The immune system is responsible for creating this inflammation in the brain of the patient.

3. Pattern recognition receptors: many of these receptors work in different manners and cooperate with each other to create a response in the brain. These prrs can be found in the brain plaques, and they develop the signs of danger which further fuels the inflammation in the brain as a matter of protection.

4. Activation of cells linked with the immune system: when the prrs begin to respond, it basically activates the immune system and the cells of the same. This is the basic reaction that causes the changes in brain which then leads to the attachment of the protein to the tissue that is diseased, in which case alzheimer's disease starts. The inflammation that we had spoken about earlier basically happens in the nervous tissue.

It is important to recognise and act on the initial signs of alzheimer's disease before it progresses beyond one's control.

Can the Immune System Trigger Alzheimer's Disease

Dementia refers to the progressive loss of memory in a human being. It does not refer to any particular disease. It is rather a cumulative representation of symptoms which signify that the person is losing his or her memory. Dementia occurs in seven stages. Read on to read more about them:

In the first stage, there is no cognitive decline and the person is mentally sound. There is no memory loss as well.
In the second stage, there is a very mild cognitive decline leading to normal forgetfulness that is often associated with progressing age.
In the third stage, there is a mild cognitive decline. The person has an increased forgetfulness and may find it difficult to concentrate on things.
In the fourth stage, there is moderate cognitive decline and the person starts forgetting even the most recent events. They cannot even travel alone or manage their own finances.
In the fifth stage, there is moderately severe cognitive decline. The person going through this stage often requires help even with their daily activities. People tend to forget even the most common things like phone and email passwords.
In the sixth stage, there is severe cognitive decline. This stage is also called middle dementia and there is prominent memory loss. People cannot even count from 1 to 10. Their speech becomes slurry. They also start having delusions.
In the seventh stage, there is very severe cognitive decline. This stage is also called late dementia. The psychomotor skills are also lost at this stage and the person may not even be able to walk properly.
Some of the early signs of dementia are listed below:

In the initial days of dementia, the person usually tends to get confused when it comes to choosing the right words. This makes them take much longer time to conclude their speech.
There might also be a change in the mood of the person.
Depression is also one of the early signs.

The person will have a tendency to forget even the most recent events that took place in his or her life. This means that they might remember what happened ten years before but they might not remember what they did in the morning.
Early signs also include failure to sense directions. People often tend to forget their addresses and the landmarks and thus become lost when they travel alone.
Confusion is also one of the common signs and this is directly correlated to the loss of memory because when a person cannot remember familiar faces, it leads to a lot of confusion within his own mind.
So, if you suspect that someone in your house is suffering from dementia, then you must look out for these early signs and seek medical help immediately. Early treatment can keep the condition from worsening.

Dementia - Stages and Early Signs!

In recent times, the advancement of medical science has substantially contributed in comprehending the Alzheimer s disease. Unfortunately, the number of individuals suffering from the disease is expected to rise in the next ten years which pose a threat to the allocation of health care resources and public health. Alzheimer s disease is thought to be a complex disease which influences a person s behavior as well as cognition through numerous mechanisms.

Can surgery be deemed as a treatment for Alzheimer s disease?
The surgery is a multicenter clinical trial which is making a new direction in clinical research. It is devised to halt or slow down the problems caused by the disease which gradually erases a lifetime of memories in elderly patients. Though there is no cure for Alzheimer s disease, it has been found that low-voltage electric charges delivered right at the brain. Only the symptomatic therapies for Alzheimer s disease are provided which do not have any effect on the evolution of the disease. The standard medical treatments for Alzheimer s disease include cholinesterase inhibitors along with a partial N-methyl D-aspartate antagonist. In most cases of mild to moderate symptoms of this disease, a combination of treatments is used according to the clinical history, age and condition of the patient.

Mental activity supporting cognition
Many patients having normal cognition or mild impairment have a fear that they may develop AD. Many experts are of the opinion that mentally challenging activities including brain teasers and crossword puzzles can be helpful in reducing the risks in such patients. Clinical trials are under the way for determining whether or not these types of activities have any substantial effect on halting the progression of AD.

Treating AD in its moderate to the severe stage
Numerous studies have shown that blockade of NMDA receptors by memantine can be used safely in combination with ChEls. This combination has been shown to delay the institutionalization in patients with Alzheimer s disease.

Treating secondary symptoms
A variety of behavioral as well as pharmacologic interventions can help in overcoming the clinical manifestations of the disease. These include anxiety, psychotic behavior, depression and agitation among others. The effectiveness of this disease can range from modest to excellent. No particular agent or dose of it can be unanimously accepted to be the sole treatment option for the wide range of clinical issues. Moreover, in the recent time, the FDA has not accepted any psychotropic agent for treating AD.

Along with these treatment options, there are behavioral interventions that can range from patient-centred approaches to caregiver training for helping manage the cognitive and behavioral manifestations of Alzheimer s disease. Last but not the least, it is very crucial to point out the significance of treatment in the early stages of AD in order to cure it better.

Alzheimer's Disease - Can Surgery Help You Treat It?

With age, just like other body functions, the mind too begins to slow down. This could lead to problems in communication, focus, recall, reasoning, and thinking. So with dementia, the person faces problems which are a combination of above-mentioned activities. Dementia is a symptom associated with many diseases and is not a disease on its own.

Alzheimer s is the main cause of dementia, followed by stroke or brain injury, Huntington s disease, and Lewy body disease. However, there are some symptoms that can be indicative that a person is gradually progressing into dementia. Watching out for these symptoms can help one seek help at an early stage, thereby helping the affected person, and slowing down its progress.

Short term memory loss: With age, people tend to forget what happened recently, and this can even be something as recent as the previous day. However, they can very clearly recollect events from the past. They might forget things like where they have placed their glasses, where the television remote control is, etc. They may also ask for the same information repeatedly, even after it is answered.
Mood changes: Rapid mood swings is observed in a person suffering from dementia. Their emotions keep changing within a matter of seconds, and they may show also less emotion than what they used to show previously.
Personality changes: Since dementia affects reasoning and judgment, someone who was earlier shy could suddenly become outgoing. Their inhibitions which led to a shy personality are lost, making them more outgoing.
Difficulty in performing regular tasks: Be it forgetting things like laying out tables, keeping things back in their places, or organising medical kits, with dementia setting in, these tasks slowly become more difficult to do. Also, learning new tasks, even simple ones, seem tough and are often not accomplished.
Losing storylines: The elderly would usually be good with telling and appreciating stories like telling tales to their grandchildren or following television soaps and stories. However, as dementia begins to set in, they tend to lose storylines, both when observing and telling.
Repeating actions: As they are not able to register things, they tend to repeat things, both in words and in actions.
Feeling lost: Things like heading out to a store to buy something and then wondering why they came there are common. Short-term memory loss can cause such situations. This confusion, especially with regard to time and things, is very common.
Spatial and time orientation: There could be problems relating to space and time, seasons, and they may often ask questions like what time it is, etc. Routine tasks like paying bills, cooking using recipe books, which were easily managed, suddenly begin to look difficult.
Apathy: Losing interest in people, hobbies, or other things like puzzles, which they once enjoyed, become boring and unenjoyable.

9 Early Symptoms of Dementia!

Dementia is the declining condition of the brain to function that interferes with daily life. It is not a disease but rather various symptoms. In such a condition, the communicative skills, as well as cognitive functions of the patient, compromised. Dementia is knowns to affect the functioning of memory, visual perception, and attention. These symptoms often cause disorientation, impaired judgment, and depression.

Speech therapy in Dementia is a way in which a speech-language pathologist can help the patients in maintaining a certain level of independence in themselves. Speech therapy helps in stimulating the cognitive abilities of the patient by engaging and practicing certain activities.

There are certain ways in which the cognitive functioning of the brain can be stimulated:

Spaced Retrieval errorless learning

Memory books and other Memory Aids

The speech therapists determine the changes in how a person is eating, swallowing, and drinking. The changes, if directed towards the improper cognitive abilities, are managed by certain strategies.

Other than normal activities, the person with Dementia also faces difficulty in communication aspects. It can either be verbal or non-verbal or both which includes gesturing, speaking, writing, and reading. The major areas that get affected by Dementia include social interaction, behavioral self-regulation, academic performance, as well as vocational performance.

It can get difficult to communicate with the person showing symptoms of Dementia. Hence, there are certain ways to help such situations.

Speaking Way

Speak calmly and clearly

Speak at a slower pace, so that the person processes the information and respond accordingly

Avoid speaking in sharp or loud voices

It is advisable to use simple and short sentences

Try speaking in a humorous way

You can also try to indulge them in conversations with others

Include them in a social group. Doing this can help in maintaining a sense of identity for the person with Dementia

Apart from this, speech therapists suggest that there are certain things you can talk about with the person of Dementia.

Whatever you are saying, say in a positive way

Try and avoid the direct questions

If you re asking questions, ask one at a time and try framing them in  yes  or  no  category

Try another way if the person cannot understand too complicated information. Don t repeat the same sentences.

Try to break down too much information in simpler explanations and sentences

A person with Dementia may have difficulty in determining particular information to be true or false. In such a case, try not to contradict them directly rather try to steer the conversation around the topic.

Take Away
A person showing symptoms of Dementia may have difficulty in carrying out simpler tasks of everyday life. Moreover, the patient may show certain behavioral, social, and physical imbalance. Such imbalance is caused by the declining cognitive abilities of the person. A speech therapist can help to overcome these disabilities through persistent training and practice.

Dementia - Know Speech Therapy For It!

With age, most body organs begin to deteriorate in their function. This happens to the brain also, thereby reducing the overall speed of functioning of most organs. While slowing of bodily movement is visible, the internal organs functioning also slows down, which is not that obvious. Memory loss or dementia is one of the main manifestations of this degeneration of the brain.

Alzheimer s is the most common form of dementia, and the associated symptoms includes reduced reasoning abilities and cognitive defects. Though it is seen only in the elderly, not all elderly people will have Alzheimer s. The overall quality of life of the affected person is reduced with difficulty remembering things that were recently learned. It is a progressive disease and as it gets more severe, a full-time caretaker may be required.

Causes: The brain cells are affected by protein masses known as plaques and tangles. These hamper the way communication between the brain cells happens as well as affect nutrition from reaching all parts of the brain. This leads to shrinking of the brain, eventually leading to memory loss and other problems. There is also a strong genetic linkage, as most people with Alzheimer s have the lipoprotein A gene.

Symptoms: Though memory loss is the most common symptom, there are other symptoms:

Being confused about places, people, and times
Inability to find the right words during conversations
Regular objects are misplaced
Becoming irritable, (in someone who was not so previously)
Mood swings
Personality changes
Inability to organise thoughts
Not able to make the right decisions
Repetitive talks and actions
Forgetfulness (not something the person always does)
Difficulty with numbers (again, not something calculations
Difficulty managing everyday tasks and minor problems
Suspicion of others (like immediate family members and friends)
Risk factors: While age is definitely a risk factor, the fact that not all aged people develop Alzheimer s is to be borne in mind. Other risk factors include the history of stroke, high cholesterol, high blood pressure, diabetes, smoking, obesity, and poor lifestyle choices.

Diagnosis: While there is no definitive way to diagnose Alzheimer s, symptoms along with brain scans and neuropsychological function testing are useful ways to confirm the diagnosis.

Treatment: This is aimed at two things reducing the rate of disease progression and treat (or reverse) symptoms if possible.

Cholinesterase inhibitors improve cellular communication in the brain and also manage depression and agitation. Memantine is used to slow the pace of disease progression.
In people with the disease, small changes are useful to help them with the symptoms. These include keeping essential things like keys and wallet in the same place, keep a daily diary to help them remember things, keep pictures of friends and family within visible distance.

Alzheimer's - An Overview!

Don't wait any longer, manage your Lewy Body Dementia online with a Lybrate doctor today

Consult for Lewy Body Dementia - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES