World sickle cell day is observed annually on the 19th of june to raise awareness of sickle cell-related diseases. It is observed to increase people's knowledge and the understanding required to face the challenges posed by the disease.


 

What is sickle cell disorder (scd)?

Sickle cell disorders or sickle cell diseases are genetic blood disorders that cause an abnormality in the red blood cells. The rbcs turn into sickle-shaped cells that stick together and block the blood flow in the body.


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Types

There are four major classifications of sickle cell diseases-


	
	Hemoglobin ss disease
	
	
	Hemoglobin sc disease
	
	
	Hemoglobin sb+ thalassemia
	
	
	Hemoglobin sb 0 thalassemia
	



 

Symptoms

One can start noticing symptoms of sickle cell in a patient at around 6 years of age. However, they can differ from person to person. Some of the most typical symptoms are-

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	Anemia
	


A shortage of red blood cells occurs due to the excessive early dying in 10-20 days. It leads to an oxygen shortage in the body.


	
	Excessive pain
	


Blockage of blood flow due to the change in shape leads to periodic cycles of pain in the body.


	
	Swelling in the body
	


As the blood circulation becomes irregular, swelling becomes a regular phenomenon.


	
	Infections
	


Sickle cell can be damaging to the spleen. It increases the risk of ailments in the body that can be prevented only by antibiotics.


	
	Delayed puberty
	


Oxygen and nutrients carried by the blood are required for growth. As a reason, irregular blood flow can lead to slow growth or delay in puberty.


	
	Vision issues
	


Infected blood vessels carrying blood to the eyes can cause damage to the retina. It can lead to visual problems.


 

Traits and treatment

As sickle cell is genetic, it is suggested to take a test that can detect any trait of the disease. It can prevent any life-threatening risks to the newborn. However, we don't have a complete cure for sickle cell disorders. There are preventive measures that reduce the adversity of the disease to an extent. Procedures like blood transfusions help greatly in minimizing the effects of the disorder.

World Sickle Cell Day: Know All About Sickle Cell Disease

Cushing syndrome occurs due to prolonged exposure to high levels of cortisol hormone. The condition, often referred to as hypercortisolism, affects women   usually between ages 25 and 40   more than men. Nearly 80% of adults and about 47% of children are diagnosed with cushing syndrome.

The most common cause of cushing syndrome is an overproduction of the stress hormone   cortisol   by the adrenal glands. However, it can also result from overuse of steroid drugs.

If you have cushing syndrome, you are likely to notice symptoms like muscle weakness, weight gain, a buffalo lump, irregular periods, sleep disorders, high blood glucose and high blood pressure.

Recent research has claimed to establish a relation between cushing syndrome and high blood pressure   or what is called hypertension in medical terms.

The link between hypertension and cushing syndrome

Hypertension refers to high blood pressure that causes the force of blood to raise against the artery walls. A number of conditions can lead to hypertension, such as poor diet and lifestyle, an underlying health issue, stress, pregnancy and so on.

As your body encounters stress, the adrenal glands produce and release cortisol in the bloodstream. Studies show that producing excess stress hormone can create a host of pathological problems in the body, including hypertension.

Hypertension is a distinguishing feature of endogenous cushing syndrome. High blood pressure in cushing syndrome has a significant correlation with the duration of hypercortisolism and results from the interaction between various pathophysiological methods regulating peripheral vascular resistance, cardiac output, and plasma volume   all of which are elevated in this state.

How to treat the condition

Cushing syndrome is usually treatable and curable. You will be prescribed to stop using steroid drugs that are likely to increase cortisol levels. If the condition does not improve after treatment, you will have to look for ways to manage the symptoms, especially by monitoring your blood pressure. Team up with your doctor and ask for ways to de-stress yourself.

Relation Between Cushing Syndrome And Hypertension: Know More

Urinary tract infections (uti) can occur anywhere in the urinary system   the bladder, kidneys, urethra, and ureter. Most of these infections affect the lower part of the urinary system   urethra and the bladder.

An infection ;confined to the bladder can be frustrating and painful. You may experience pain during urination, and pus or blood in the urine. However, the condition becomes worse if the infection spreads to the upper part of the urinary system, particularly to the kidneys, triggering nausea, ;vomiting, and severe pain in the back.

If uti is left untreated, it can potentially lead to kidney damage   a condition known as pyelonephritis.

How does untreated uti affect the kidneys?

Untreated urinary tract infections can cause the kidneys to swell up and damage them permanently. The infections initially begin in the lower tract of your urinary system. Then the bacteria slowly enter your body through the urethra and begin multiplying and spreading up to the bladder. The bacteria eventually travel to your kidneys through the ureters.

Some people are at higher risk for kidney damage due to urinary tract infections. This includes  


	
	Pregnant women
	
	
	Elderly people
	
	
	People with kidney problems
	
	
	Someone with a weak immune system
	


Signs to watch out for

An untreated infection in the bladder that has spread to the kidneys is associated with symptoms, such as the following  


	
	Chills and ;fever
	
	
	Vomiting and nausea
	
	
	Pain in either side of your lower back
	


You should visit a doctor right away if you notice the above uti symptoms. The condition requires immediate medical intervention in order to prevent damage to your kidneys.

Symptoms of painful utis can be managed by combining medications and lifestyle remedies. Consult a specialist to diagnose the condition early and seek appropriate treatment to avoid complications.

Untreated Urinary Tract Infections And Kidney Damage: Know The Connection

Cervical cancer is a ;cancer that affects the cells of the cervix in women. The cancer is believed to be caused by exposure to human papilloma virus (hpv). Also, there are certain factors that are linked to an increased risk of acquiring hpv and developing cervical cancer.

What Are The Major Risk Factors Of Cervical Cancer?

While yoga is mainly considered to be a physical process that unites our spiritual conscience, there's more to it. Meditation, prayer, breathwork, and rituals are some self-disciplinary practices that make up the entirety of yoga.

 

Benefits

Apart from physical well-being, yoga also ensures that your overall health gets a boost and you feel rejuvenated. Some scientific benefits of yoga are-

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	Increases flexibility
	


Yoga offers many asanas and styles to choose from and almost all of them contribute to improving flexibility. Yoga acts as a catalyst to increase mobility in older people.


	
	Relieves stress
	


Studies suggest that the second most cited reason for people to practice yoga is that it releases stress. Science proves that yoga helps lower the stress and tension levels in individuals.


	
	Boosts mental health
	


Some studies have observed that yoga is an excellent practice to treat major depressive disorder (mdd). Both movement-based and breathing-based yoga therapies are helpful to improve mental health.


	
	Reduces inflammation
	


Reports suggest that yoga reduces inflammation in the body. As a result, it prevents any chronic disease.


	
	Increases strength
	


Some styles and asanas of yoga can also be strength building. Yoga s effectiveness at improving physical strength has been suggested by many reports.


	
	Reduces anxiety
	


There are numerous anxiety disorders that need care such as anxiety disorders, social anxiety, and phobias. Yoga in the form of meditation helps in reducing the symptoms of the same.


	
	Boosts immunity
	


Excessive stress affects your immune system directly. One is more susceptible to diseases if the immunity is weak. As yoga is a proven way to relieve stress and reduce inflammation, it helps the body develop stronger immunity with time.


	
	Improves balance
	


Balance is important for performing daily movements. Yoga has shown considerable progress in improving bodily balance. Being consistent with yoga makes sure that you get long-lasting benefits as well.


	
	Cardiovascular functioning
	


Pranayama or yogic breathing greatly helps numerous systems in the body. Controlled breathing lowers the chances of change in heart rate, stroke, and more.


	
	Improves quality of sleep
	


Yoga improves the quality of sleep. It is also because of the aftereffects of the exercise. However, yoga has some qualities like mental calming and stress relief that allow a sound sleep.


	
	Boosts bone health
	


Isometric contractions in yoga provide a holistic engagement of bones. They also reverse the bone loss related to osteoporosis and osteopenia.


	
	Improves brain functioning
	


Yoga stimulates the functioning of the brain and boosts energy levels. Studies suggest that it can improve executive functioning, mental flexibility, task switching capabilities, and memory.







 

Scientific Benefits Of Yoga

A brain tumour is a life-threatening situation. Most of the symptoms of the brain tumour are alike, but not all tumours are malignant. The most common type of brain tumour is meningioma. You may even don t need surgery in this case as they are really not dangerous or life-threatening.

 

Here are some of the facts you should know about meningioma:

 ;

Meningioma can develop in numerous locations

 

Cells in the meninges, the lining of the brain and spinal cord, give rise to these tumours. In fact, they are not brain tumours at all, because they are not caused by the altered brain cells. ;

However, they continue to grow inside your sull, indicating that you should now take immediate steps. Meningioma can produce brain tumour symptoms if it grows or creates swelling that presses against the brain or other tissues in the skull.

 

Meningioma symptoms vary depending on the size and location of the tumour

 ;

Meningioma can cause vision-related issues, headaches or seizures which are all common signs of a brain tumour. A headache, even a strong one, is seldom an indication of meningioma or any other type of brain tumour on its own. 

 ;

Other tumour sites can influence your sense of smell, vision, hearing and even the pituitary gland s function.

 

Meningioma diagnosis usually happens when the doctor is looking for some else

 ;

The discovery of a tumour on a ct scan or mri while investigating the patient for another cause, such as a head injury or another neurological condition, is called an accidental diagnosis. When a doctor identifies a meningioma, you will undergo additional testing to determine how the tumour will behave. A neurosurgeon will decide whether to remove the tumour or just monitor it to see whether it grows based on these findings. 

 ;

Majority of meningioma does not spread

 

Being diagnosed with meningioma, especially a large one, might be shocking, but these tumours are usually non-dangerous. Tumour cells are unlikely to spread to other sections of the body as a result of this. ;

Meningiomas, on the other hand, can grow silently for years without creating any difficulties and they can grow to be enormous.

 

Things You Should Know About Most Common Brain Tumours

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