C-reactive protein ;is a type of protein produced by the liver in response to an infection ;or inflammation. When your body contracts an infection, the white blood cells produce proteins to fight it. Some of these proteins activate the liver into producing c-reactive protein. For many years, the crp ;blood level has been used to ascertain the level of infection or inflammation.

Assessing the risk of heart disease ;with c-reactive protein

The level of crp is a potential indicator of how likely you are to develop cardiovascular diseases. This is because the development of atherosclerosis is linked with inflammation within the walls of your blood vessel. This results in higher levels of c-reactive protein in atherosclerosis patients than in those without the disorder.

The greater the crp levels, the more chances you have of being affected by cardiovascular disorders. The test also determines the risk of a second attack.

The value of knowing your crp levels depends on whether you come under one of three cardiovascular risk groups.


	
	High risk   not important to know crp because you should be combining lifestyle changes and aggressive treatment to reduce risk
	
	
	Intermediate risk   helpful to find out crp levels, as it can provide vital information crucial in deciding the next line of treatment
	
	
	Low risk   even if your crp levels are high, you will not be at risk   due to negligible risk factors and low cholesterol levels   that should require more than just lifestyle changes
	


To find out crp levels you will have to take a blood test. C-reactive protein is classified into  


	
	High   equal to or greater than 3
	
	
	Intermediate   between 1 and 3
	
	
	Low   below 1
	


If you are having a c-reactive protein test to check for heart diseases, your healthcare provider may recommend a cholesterol test as well. A number of other tests may also be prescribed to evaluate your risk further.

How C-reactive Protein Can Pose A Risk For Heart Disease?

When abnormal cells grow inside the brain and are in the form of a mass the condition is called a brain tumour. However, on the other hand, brain cancer is a disease of the brain in which cancer cells (malignant cells) arise in the brain tissue. Cancer cells grow to form a mass of cancer tissue (tumour) that interferes with brain functions such as muscle control, sensation, memory, and other normal body functions. 

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Some brain tumours are cancerous while others fall under the category of non-cancerous ones.

Brain cancer is actually the abnormal growth and uncontrolled growth of the cancer cells in the brain, that forms a tumour in the brain. Tumours can be either benign or malignant.

Benign brain tumours are abnormal collections of cells that reproduce slowly and usually remain separate from the surrounding normal brain.

Malignant tumours reproduce and grow quickly. Their borders are hard to distinguish from the normal brain around them.

 

The underlying cause of primary brain cancer, cancer that begins in the brain, is not known. Secondary brain cancer is caused by a cancer of another organ in the body, such as the breast, prostate, kidney, skin, or bone, that has spread to the brain.

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The brain tumours originate in the brain itself. Tumours start to develop if there are mutations in the dna. It is because of these mutations that cells of the brain increasingly grow and divide. Usually, in adults, the primary brain tumours are uncommon in comparison to the secondary brain tumours.


 

There are few early symptoms of brain cancer, but as the tumour grows within the confines of the skull, it causes increased intracranial pressure and exerts pressure on the brain, causing signs to develop.


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Brain cancer occurs when there is an uncontrolled growth of cancer cells in the brain that form a malignant brain tumour. The underlying cause of primary brain cancer, cancer that begins in the brain, is not known. Secondary brain cancer is caused by a cancer of another organ in the body, such as the breast, prostate, kidney, skin, or bone, that has spread to the brain.


 

What Is The Significant Difference Between Brain Tumour And Brain Cancer?

When abnormal cells grow inside the brain and are in the form of a mass the condition is called a brain tumour. There are various types of brain tumours that exist. Some of the brain tumours which exist are malignant or cancerous while other may be non-cancerous. A brain tumour can begin in any part of the brain and spread to other parts of the body or vice-versa. The growth rate of brain tumours is different for each individual suffering from it. As per studies, every 2 in 1, 00, 000 people are said to be affected by a brain tumour in india. However, it may come as a relief to some as not all brain tumours are cancerous or life-threatening. Some are benign tumours and seldom pose any threat to the affected individual.

 

Types of brain tumor

Brain tumours may be primary or secondary.

Primary brain tumour

In this type of brain tumour, the abnormal mass of cells that originated in the brain does not metastasize to the other organs. Based on their location in the brain, the primary brain tumours may be of the following types.


	
	Gliomas: one of the most common types of primary brain tumours, gliomas can have their origin in the spinal cord or the brain. Some of the common types of gliomas include astrocytomas (originates in the cerebrum of the brain), glioblastomas (these tumours form from the astrocytes which form the supportive tissues of the brain), ependymoma (these develop from the ependymal cells which are present within the cns), oligodendrogliomas (these tumours are found to arise from the oligodendrocytes).
	
	
	Schwannomas: also called acoustic neuromas, these primary brain tumours form on the nerves that play an important role in regulating the balance and hearing from the inner ear to the brain.
	
	
	Meningiomas: these types of tumours are usually benign and have their origin in the meninges (membranes surrounding the spinal cord and the brain).
	
	
	Primitive neuroectodermal tumours (pnets): primitive neuroectodermal tumours (pnets) are rare malignant tumours that originate from the fetal (embryonic) cells in the brain.
	
	
	Pituitary adenomas: as the name suggests, these tumours arise from the pituitary gland located at the base of the brain.
	
	
	Medulloblastomas: common among children, these malignant primary tumours develop in the brain (lower back) and gradually spread via the spinal fluid.
	


Other types of primary brain tumours include craniopharyngiomas and germ cell tumours.

Secondary brain tumours ;

Unlike the primary brain tumours, these tumours have their origin in the other body parts and organs (mostly in the lungs, skin, colon, breast, and kidney) and then gradually metastasize to the brain. Secondary brain tumours are found to be more common.

 

What Are The Different Types Of Brain Tumours?

Air pollution affects the overall health of a human being. Whether it comes out of exhaust fumes from cars and factories or smoke from burning stubble air pollution, it is a cause of major concern. The effects of this can be seen in the growing number of asthma and other respiratory diseases. These diseases affect adults and children alike, however, it is the younger generation and elderly people who are more susceptible. Hence, it is extremely important to care about the quality of the air you breathe in. 


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What is the significance of the air quality index (aqi)?

The air quality index is a visual representation of pollutant levels in the air around you. A quick glance at this colour coded map can tell you if the air outside your home is likely to harm you or not. The code is broken down into 6 levels ranging from green which signifies minimal impact to red which marks pollution levels that can harm a healthy person and seriously impact those who are already ill. The higher the aqi, the higher the level of air pollution.

 

What are the steps to reduce air pollution?

Simply talking about how there need to be stricter laws about car emissions and the burning of waste will not help you. Here are a few things you can do to protect yourself and your family from the ill-effects of air pollution.


	
	Carpool: exhausts from cars and other vehicles are one of the biggest causes of air pollution. Do your part to reduce air pollution by restricting the amount you use your car. Try taking public transport to work or carpooling with colleagues. Similarly, avoid making individual trips every time you need something from the market. Make a list and when it s long enough, then step out.
	
	
	Limit indoor pollution: do not smoke indoors. When cooking, keep the exhaust fan on so that the smoke produced does not collect indoors. Avoid spraying air fresheners etc. While they may temporarily make the air smell fresh, in the long run, they contribute to air pollution.
	
	
	Use public transport try to use public transport and avoid the use of personal vehicles.
	


How to protect yourself from air pollution


	
	Refrain from morning walks routines to later hours.
	
	
	Use n95/99 face masks whenever you step out.
	
	
	Use air-purifying plants to purify the air around your surroundings.
	
	
	Ventilate your kitchen, and bathroom to keep yourself away from air pollution.
	
	
	Restrict outdoor activities for kids if there is a high level of air pollution
	
	
	Use air-purifiers in your surroundings.
	
	
	Try to take steam with a few drops of eucalyptus oil every day.
	
	
	Keep your car s environment fresh.
	
	
	Ventilate your home, open your windows and doors and allow the air to circulate during mid hours.
	
	
	Eat jaggery (aka gurr) to flush out pollutants from your lungs.
	
	
	Consume a diet rich in vitamin c, omega fatty acids
	


Hence, the other way to cut down this pollution is by bringing significant lifestyle changes in our daily living. Cutting down the number of diesel and petrol vehicles can also prove helpful. People should shift to cng and electric vehicles for daily commuting. These efforts, if practiced on a regular basis, can bring a huge decrease in pollution.

Air purifiers can also be a healthy option for indoor purposes.

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Why Should You Care About Air Quality?

Cushing syndrome occurs due to prolonged exposure to high levels of cortisol hormone. The condition, often referred to as hypercortisolism, affects women   usually between ages 25 and 40   more than men. Nearly 80% of adults and about 47% of children are diagnosed with cushing syndrome.

The most common cause of cushing syndrome is an overproduction of the stress hormone   cortisol   by the adrenal glands. However, it can also result from overuse of steroid drugs.

If you have cushing syndrome, you are likely to notice symptoms like muscle weakness, weight gain, a buffalo lump, irregular periods, sleep disorders, high blood glucose and high blood pressure.

Recent research has claimed to establish a relation between cushing syndrome and high blood pressure   or what is called hypertension in medical terms.

The link between hypertension and cushing syndrome

Hypertension refers to high blood pressure that causes the force of blood to raise against the artery walls. A number of conditions can lead to hypertension, such as poor diet and lifestyle, an underlying health issue, stress, pregnancy and so on.

As your body encounters stress, the adrenal glands produce and release cortisol in the bloodstream. Studies show that producing excess stress hormone can create a host of pathological problems in the body, including hypertension.

Hypertension is a distinguishing feature of endogenous cushing syndrome. High blood pressure in cushing syndrome has a significant correlation with the duration of hypercortisolism and results from the interaction between various pathophysiological methods regulating peripheral vascular resistance, cardiac output, and plasma volume   all of which are elevated in this state.

How to treat the condition

Cushing syndrome is usually treatable and curable. You will be prescribed to stop using steroid drugs that are likely to increase cortisol levels. If the condition does not improve after treatment, you will have to look for ways to manage the symptoms, especially by monitoring your blood pressure. Team up with your doctor and ask for ways to de-stress yourself.

Relation Between Cushing Syndrome And Hypertension: Know More

People with sickle cell disease often experience myriad symptoms of the disease that can be controlled by the right nutrition. Reports suggest that nutrition is an increasingly significant factor to prevent symptoms such as slow growth, lower body mass, joint issues, infections, pain crises, and anemia.

There is a greater than the typical requirement for both calories and micronutrients.

The nutritional requirement of a sickle cell patient emphasizes more on vegetables, fruits, whole grains, and more similar food items. These can prevent any deficiencies in the body and also decrease any chances of disease exacerbation.

 


	
	High-calorie nutrient-dense diet
	


The usual energy intake in a sickle cell patient is normally lower than the average values. It is a case even when the condition is asymptomatic where the requirement drops to half the level. As a result, people with sickle cell diseases (especially kids) are at higher risk for impaired growth and considerably lesser fat and fat-free mass, with obesity also posing a risk. It is suggested to have adequate energy supplements in the diet to reach the minimum sufficient requirement of the body that can be done only by proper nutritional assessment.


	
	Adequate fluids
	


Avoiding dehydration is another significant factor to avoid any severe symptoms of sickle cell disease. Sickling of the erythrocytes aggravates in patients who perform hardcore physical work in the heat without drinking enough fluids. This leads to dehydration and can even result in constipation.


	
	Micronutrients
	


Micronutrient deficiencies can be found in sickle cell patients up to a great extent. Several vitamins and minerals like vitamin a, b6, c, e, carotenoids, zinc, and magnesium are often found in fewer numbers in scd patients. A significant drop in blood-antioxidant status may result in acute chest syndrome. The supplementation of these vitamins and minerals can reduce the number of sickled cells in the body. Plant phenols and flavonoids may also help in lowering oxidative stress.


	
	Calcium-rich food
	


Getting plenty of calcium-rich food like dairy products, leafy vegetables, cereals, and fruit juices aids the child's growth and development. This may lead to a stronger physical structure and a greater resistance to the disease.


	
	Omega-3 fatty acid
	


There are reduced proportions of omega-3 polyunsaturated fatty acids in sickle cell patients. These acids aid the fluidity of red blood cell membranes. As a result, they prevent sickle cell crises. Supplemental docosahexaenoic (dha) and eicosapentaenoic (epa) have shown numerous therapeutic benefits in scd patients.


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Role Of Nutrition In Sickle Cell Disease

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