Most people believe kidneys to be organs solely responsible for the filtration of blood and production of urine. But the truth is that the kidneys perform a host of vital functions in the body which include regulation of blood pressure, blood volume, and blood Ph. Around half of the individuals affected by lupus suffer from kidney problems, and the most affected part is the glomerulus whose function is filtering substances from the blood.

Effects of lupus nephritis on the kidneys
Lupus itself doesn t lead to kidney infection or inflammation. But lupus nephritis, which is the Systemic lupus erythematosus (SLE) that affects the kidneys and the medications used for treating the condition tend to suppress the immune system. It makes the person affected with lupus vulnerable to the infections of various types. It is one of the most severe conditions of that could be encountered by a person wherein the immune system starts attacking various parts of the body as they would tackle a disease.

Lupus nephritis makes the kidney unable to remove the waste materials effectively from the blood. This leads to loss of control over the amounts of fluids regulating in the body. As a result, an abnormal amount of waste can build up in the blood resulting in edema or swelling.

When left untreated, these conditions can cause scarring along with permanent damage to the kidneys and end-stage renal disease. When a person has end stage renal disease, he or she needs regular filtering of the waste products of the body with the help of a machine. In severe cases, a kidney transplant may be required to ensure that at least one kidney is working properly.

Individuals who are susceptible to developing lupus nephritis:
A person with lupus may see the symptoms of lupus nephritis within 5 years and the people aged between 20 and 40 years are most vulnerable to it. In some common instances, it is seen that lupus nephritis is leading to unexplained weight gain along with swelling and puffiness in different parts of the body such as ankles, hands, eyelids, legs, and feet. During the first stages, these symptoms are often ignored which causes worsening of the condition. The urine may also become frothy or foamy with a reddish tinge in it. It is estimated that about 40 percent of children having lupus would develop kidney complications. Lupus nephritis may also cause increased urination, blood in the urine and elevated blood pressure.

If you have lupus, it is imperative to consult with a nephrologist. Testing a sample of the urine can help in showing the problems in the functioning of the kidneys. Your doctor will advise you about the diagnostic tests that can help in determining whether the disease has progressed to severe levels and start with the treatment process accordingly.

How Does Lupus Nephritis Affect Your Kidneys?

Kidneys are an important part of the human body. From filtering wastes from the blood to maintaining the blood pressure and red blood cell count in the body, the kidney does it all. Both the kidneys are essential organs and should there be any discomfort in the kidneys, one should consult a medical practitioner as soon as possible. Kidney failure is a common problem in people. This issue manifests itself with certain signs and symptoms. One should listen to these symptoms and act quickly before the condition worsens. Here are some of the signs and symptoms of kidney failure.

Interestingly, in the initial stages, kidney failure portrays no symptoms. It starts developing slowly and steadily causing discomfort in other parts of the body and hindering the working of other organs.

Weakness: If you are suffering from kidney failure, you will start feeling weak. Weakness is however not a symptom which can confirm a kidney failure. Weakness is caused due to many other health issues and thus, you need to verify with other symptoms to be sure of the fact that you are suffering from kidney failure only.

Shortness of Breath: You may start experiencing heavy breathing right after doing some rigorous work. In fact, you might feel shortness of breath or be panting for long moments after climbing just a set of stairs. Shortness of breath is quite common indicating that the body is getting tired after doing work. Such indication, more than once a day, calls for an immediate check up of the body.

Lethargy: While most people, especially the young generation to those in the early thirties jokingly declare themselves as lazy people; lethargy, however, is a symptom of many diseases. Various health issues develop if you feel lethargic of working. Apart from kidney failure, diabetes is also manifested in lethargic body movements. At times, just getting out of the bed in the morning seems very tiring and one continues to lie on the bed even after he/she is fully awake.

Stomach Pain: If you experience pain in the stomach, especially in the sides, then it should be immediately checked by a medical practitioner. Doctors say that kidney failure can bring about stomach pains.

Unusual Urine Discharges: This would include clear urine discharges which indicate that the kidney has stopped filtering the waste products.

Thus, these are some of the most important and common symptoms of kidney failure. If you notice any of these, it is advised to visit a doctor for a check up.

Symptoms of Kidney Failure

When do kidneys need dialysis?

Kidneys are a pair of organs that are located on either side of the spine, each about a size of a fist. The kidneys help in purifying blood by removing toxins, waste materials and excess fluids from the human body. Disorders and dysfunctions of the kidney can lead to severe and often fatal consequences. When the kidneys stop functioning as they are supposed to, dialysis is performed to resume normal functioning in the body.

Dialysis is a type of treatment, which filters and purifies the blood with the aid of a machine. It is an artificial way of purifying blood. There are two types of dialysis, namely hemodialysis and peritoneal dialysis. Hemodialysis, the most common form of dialysis, which involves using a manmade kidney called a hemodialyzer, which removes toxins and waste materials from blood.

Peritoneal Dialysis, on the other hand, is a type of treatment which involves implanting a catheter in the stomach. During the procedure, a fluid called dialysate flows into the abdomen that absorbs all the waste material, which is consequently drained out of the body.

You may need a dialysis if:

- Your kidneys are dysfunctional
- When waste materials and toxins start to accumulate in the body
- In an event of an injury or accident to the kidney such as internal lacerations (wound caused by the tearing of a tissue)
- If the creatinine (a type of a chemical waste product) level falls to 10-12 cc/minute
- In an event where the kidneys aren't able to work properly leading to accumulation of toxins, irregular amounts of chemicals in the body and other dysfunctions

Weakening of the abdominal muscles and weight gain are some of the risks involved in dialysis. Dialysis is a temporary treatment and serves to function till the time the actual kidneys get repaired. In chronic cases of kidney disease, kidney transplant may perhaps be the last resort.



When Do Kidneys Need Dialysis?

A kidney transplant is a surgical procedure that patients of kidney disease go through in order to replace a non functioning kidney with a live one that is healthy and functions well. Other methods to treat this disease also include dialysis, which basically is an artificial way of doing what our kidneys are designed to do. When dialysis does not work, many doctors recommend a kidney transplant. A replacement or donated kidney can come from a living donor or a non-living donor. This new kidney will mostly work towards keeping the blood clean, which is a function that stops when the old and diseased kidneys fail.
 
So, here's a list of five essential facts that you need to keep in mind if you are looking at a kidney transplant:

1. Donors: While there are living and non-living donors, the doctor will have to ensure that your donor is someone who has no medical history of complications, kidney disease or any other medical condition like diabetes or hypertension. Also, the donor would have to have two proper functioning kidneys. Further, one of the most important factors is the blood group. The blood group of the donor and the patient must match for the transplant to be possible.

2. Procedure: During the surgery, the patient will be under general anesthesia. The surgeon will make an incision in the lower abdomen area and the blood vessels of the new kidney will be connected surgically with the vein and iliac artery of the patient. Thereafter, any excess fluid will be drained before wrapping up the surgery.

3. Rejection: The patient's body may also reject the kidney. The immune system of the patient may mistake the new kidney as an attacking body and its natural defenses may work against it, which will lead to complications. For this, doctors usually prescribe immunosuppressant medicines that will help in preventing such an eventuality. 

4. Longevity: While a living donor's kidney may last longer, a non-living donor's kidney will not enjoy such a long life. In such cases, a second transplant can be conducted.

5. Diet: After the transplant, the patient will be required to go through a number of measures like coughing to show that the lungs are clear, as well as administration of fluids and some amount of examination and dialysis. Also, the patient will have to have a special diet that includes raw fruits and vegetables, and plenty of non-fat dairy ingredients.

A kidney transplant is a major operation that can change your lifestyle in the long run. 

5 Things You Should Know About Kidney Transplant

A kidney transplant is a procedure that employs an operation to transplant properly functioning kidney in the body. The main job of the kidneys is to remove the excess waste from a person s body with the help of a filtration process. When the kidneys stop filtering the toxins properly, they become diseased as harmful waste products and toxins begin to accumulate in the body. Following this, the patient has to go through treatment measures like dialysis or kidney transplant.

Read on to know the five things you should keep in mind about a kidney transplant.

Treatment: Transplant is one of the best ways to treat chronic kidney disease stage-V, until unless it is contraindicated. Life becomes near normal after transplant, though there is a possibility of rejection of transplant kidney. Patient has to take immunosuppressive medication life long. 
Medication: Medications are mainly for:
To prevent rejection: Patient takes immunosuppressive medications life long. 
Prevention of infection: Patient has to take care all the measures to prevent infections as they are more prone to infections. 
Other medication: To control diabetes, HTN etc. 
Family Only: The donors are from family or emotionally related or cadavers (after brain death). HLA-matched donors are better because of less chances of rejections and first reduction of immunosuppressive. 
Doing Your Part: Once transplant is done - patient becomes normal and he/she lives a normal life. However, they have to take regular medications and to protect themselves from various infection. 
End Stage Renal Diseases: These diseases includes diabetes mellitus, HTN, polycystic kidney disease, chronic glomerulonephritis or interstitial nephritis etc.
Consult your Nephrologist before going for renal transplant for detailed check up or line of action.

Kidney Transplant - 5 Things About it !

As we all are aware that waste products in the blood are passed through urine. This filtering process is done by the kidneys as it separates the waste products including minerals and salts, which have to be passed out through urine. Many times, these minerals and salts get stuck in your urinary tract and over a long period, this forms kidney stones. They can vary in size from a ping pong ball to the size of a sugar crystal. They are not noticed till the time they cause a blockage. Sometimes, they cause immense pain if they start breaking or are pushed into the ureters (narrow ducts which lead to the bladder).

Symptoms of kidney stones:
1. Immense pain in the groin, belly and back.
2. Pain while urinating and urination occurring frequently.
3. Blood found in the urine (haematuria).
4. Vomiting and nausea.
5. Feeling extremely restless and not being able to lie still.

Kidney stones can also cause a kidney infection. Signs of kidney infection include:
Kidney stones can also cause infection in the kidneys as they block the passage of urine to the bladder by blocking the ureters. This leads to build up of the waste product which can result in an infection. Some of the symptoms of kidney infections could be:
1. Feeling chilly and shivering on your skin.
2. High temperature of 100.4 F (38C) or more.
3. A feeling of fatigue or weakness.
4. Immense diarrhea
5. Bad smelling and cloudy urine.

Types of Kidney stones:
1. Struvite stones: It contains ammonia and magnesium. It is usually quite large and horn- shaped.
2. Uric acid stones: Brown, smooth and softer than other kinds of kidney stones.
3. Cystine stones: They are yellow and don t look like stones. They usually resemble crystal.
4. Calcium stones: It is composed of calcium.

What causes kidney stones?
Kidney stones can occur due to several factors. It usually forms when urine generally contains crystal substances like uric acid, calcium and oxalate. Your urine might not be able to dilute these substances resulting in the perfect environment for the formation of kidney stones. In case you are showing any of the symptoms mentioned above, you should visit you doctor immediately before the problem can worsen.

Common Symptoms of Kidney Stones

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