SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

The coronary arteries supply the heart with oxygen-enriched blood and nutrients. If these arteries become damaged or diseased; they could cause Coronary artery disease or CAD. Plaque deposits on the walls of the arteries are the most common cause of this disease. This plaque is usually the result of high cholesterol levels. As the plaque builds up, the passage of blood flow is reduced. This reduces the amount of blood that reaches the heart. In cases of a complete blockage, CAD can even cause a heart attack. Because of its slow progression, this disease is often not diagnosed until it reaches a dangerous stage. However, it can be prevented and treated if diagnosed in time.

In the early stages of CAD, symptoms are not very noticeable. Symptoms become visible only when blood flow to the heart reduces and the heart has to pump harder than normal. The most common symptoms experienced include:

Chest Pain: This is also referred to as angina. It may feel like a tightening of the chest or pressure on the chest as though someone is pressing against it. This type of chest pain may be triggered by emotional or physical stress. It is usually relieved within a few minutes of stopping the activity. Women may experience this pain as a sharp, fleeting pain in the back, arm or neck.
Breathlessness: When the heart does not receive enough blood, it has to work harder to pump blood through the body. This may be translated to breathlessness of shortness of breath when performing any type of physical activity. It can also cause extreme fatigue.
Heart Attack: A heart attack is the most severe symptom of coronary artery disease. This is caused by the complete blockage of a coronary artery. A heart attack can occur without any symptoms or be preceded by slight symptoms. The signs of an impending heart attack include pain in the chest and shoulder, shortness of breath and extreme sweating. The chest pain may also travel to the lower jaw. These symptoms are more pronounced in men as compared to women. Women have a higher tendency of experiencing atypical signs such as extreme fatigue.
Other symptoms that might indicate coronary artery disease are dizziness, nausea and an irregular heartbeat. The good news is that this disease can be prevented. Staying physically active, maintaining a healthy weight, reducing stress and eating a low fat and low salt diet can help reduce the risk of CAD.

Coronary Artery Disease (CAD) - What Are The Symptoms?

For long, there have been campaigns and discussions about the harmful effects and diseases associated with alcohol consumption. In most cases, it is not the alcohol, but the quantity consumed that affects a person. Limited consumption of alcohol can, in fact, work to your advantage. Alcohol, when consumed in moderation, helps to avert, check or improve many medical conditions and health ailments.

Deal with common cold effectively: According to research, the antioxidants present in wine helps to fight common cold better. Limited intake of alcohol, red wine to be precise (~1-2 glasses per day), can, thus, help to reduce the instances of common cold significantly.
Weight loss made easy: Studies conducted by the Oregon State University suggest that certain varieties red wine (the Red Muscadine Wine) can play a pivotal role in weight reduction. The Red Muscadine, a variety of wine grapes used to make red wine contains ellagic acid. It is this ellagic acid that helps to cease or slow down the growth and development of the fat cells. Red wine also helps to manage fatty liver effectively.
Keep cardiovascular diseases at bay: The high-density lipoprotein (HDL), also known as the Good Cholesterol is indeed good for the body. It acts as a shield, keeping the heart hale and hearty. Moderate alcohol consumption helps to elevate the level of HDL. One of the main reasons attributing to heart attacks are the small blood clots that block the arteries of the brain, heart, and neck. Alcohol (limited intake) has been able to put a check in the formation of such blood clots.
Reduced instances of cognitive impairment: Reports suggest that people who consume alcohol within limits are less likely to develop dementia and Alzheimer's disease. Moderate consumption tends to make the brain cells fit and more active, thus, enabling the cells to deal with stress and other related factors.
A little wine for a better libido: Limited consumption of wine is good for a better sexual life. Research indicate that the antioxidants present in wine act as a catalyst, resulting in an improved libido (lowers the incidences of erectile dysfunction in men). A little wine can work wonders for women as well (increasing their sexual desires and feelings).
Enjoy a diabetes-free life: Type 2 Diabetes and the associated ailments and complications can make life miserable. However, people who consume a small quantity of alcohol (preferably 1-2 glasses per day) are at a lower risk of developing diabetes (Type 2). A path-breaking finding indeed!
People with moderate alcohol consumption are also at a lower risk of developing gallstones. The high silicone content in beer helps to strengthen the bones, but only when consumed within limits. Beer is also rich in calcium, magnesium, and vitamins (thiamine, riboflavin).

Alcohol In Controlled Quantity - Can It Be Good For You?

Symptoms of heart attack

A heart attack (myocardial infarction) should not be confused with stroke or heart failure. It is the condition which causes major damage to heart muscles because of sudden blockage by a blood clot. The most common symptom of heart attack happens to be chest pain. Heart failure and ventricular fibrillation are probably the most common complications in this condition. 

Clear symptoms of heart attack are:

1. Feeling vaguely ill - very vague feeling of illness is one symptom. You cannot really put your finger on what is wrong with you, but you do feel unwell.

2. Pain in left arm - pain in the arm, mainly the left arm is also one of the symptoms of an impending heart attack.

3. Sweating and heartburn - a lot of people have reported experiencing sweating, indigestion and heartburn before a heart attack. If you are sweating profusely and without any particular reasons, or having an unbearable heartburn, consult a medical specialist immediately.

4. Chest pain - feeling of fullness or tightness in the chest followed by pain is also a symptom of a heart attack. A lot of people have reported to ignore it; kindly don't.

5. Breathlessness - sudden shortness of breath and inability to do a lot of work at one point of time is not a good thing. This could be an indication of a heart attack.

6. Silent attack - the scariest of all is silent heart attack. At times, it comes with no symptoms at all. A person could be visibly physically fit, and suddenly have an attack. This usually happens with those who are suffering from diabetes mellitus.

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All You Need To Know About Heart Attack Symptoms

Hypertension is a condition where the blood has to exert extra pressure to flow through the blood vessels. While there is a genetic component to it, the more strong contributing factors are modified lifestyle and dietary changes. There are also a lot of environmental changes that have contributed to this new epidemic. While earlier people in their 50s and 60s would be diagnosed with hypertension, now there are people in 30s and 40s taking hypertension pills. Excess fat accumulation is the major cause of hypertension in younger patients.

There begins the complexity of the issue. Hypertension which requires medications to control it, they lead to side effects and bring in a host of other diseases like diabetes, and obesity which in turn bring in a whole lot of complications. A more easy way to manage would be to prevent and of course, after onset, look at how naturally it can be managed.

Ayurveda has numerous substances that have been proven to have beneficial effects in controlling blood pressure over the past 1000s of years.

1. Celery or ajwain helps blood vessels to dilate and reduces concentration of stress hormones in the blood.

2. Ashwagandha has a wide range of actions and improves the body's ability to handle physical and mental stress. This in turn improves blood pressure, obesity, and depression.

3. Citrus fruits contain vitamin c which prevents fragility of the capillaries (thinner blood vessels).

4. Cow's urine prevents hardening of blood vessels and is of curative value in those who have blood pressure due to hardening of blood vessels. 

5. Triphala which is a combination of amla, haritaki, and bibhitaki helps reduce inflammation that leads to blood pressure, thereby helping to control it.

6. Jatamansi - by helping the free radical damage on the arteries, it protects the arteries and prevents cholesterol accumulation. It also is a very well-proven stress reliever and has additional benefits on hypertension.

7. Arjuna - by helping the metabolism of the bad cholesterol in the liver, this protects the inner lining of the heart and thereby helps control hypertension.

8. Calcium and potassium containing substances help remove sodium and thereby improve blood pressure.

9. Natural herbs like brahmi, sarpagandha, shankhpushpi, and chandana are effective ayurvedic cure and treatment for hypertension.

10. Rasayana treatment from ayurveda is having excellent results, however everyone requires unique rasayan as per their body types.

11. Watermelon helps in dilation of the blood vessels.

12. Aloe gel, barberry, calamus, valerian, skullcap, gotu kola cayenne, myrrh, motherwort, hawthorn and jatamansi have all been shown to help manage hypertension over thousands of years.

13. A glass of warm milk mixed with saraswat powder is also helpful for patients with high blood pressure.

These are natural remedies which were a part of diet since times immemorial. Including them in the diet, reducing processed foods, regular exercise, avoiding alcohol and smoking can be some natural ways to prevent and if required control hypertension. Stress is here to stay, but can definitely be managed with a little conscious effort.

Control Blood Pressure With Ayurveda

On an average a person consumes nearly 800 calories daily from added sugar. This does not just include natural sugar found in fruits or milk but the processed sweet sugar as well, that is added to cakes, tea, coffee, confectionery and even pasta sauce and salad dressing. However, it is possible that you can limit your sugar intake or even quit it to get some truly amazing benefits.

When you take this hard decision, you may experience withdrawal symptoms such as mild depression, anxiety or restlessness. But if you remain adamant and continue with your decision, your body will soon show some incredible results that you couldn't have imagined.

Here are a few of them:

1.&nbsp;Your heart will beat happily

Sugar raises insulin levels that activate the responses of sympathetic nervous system thereby elevating your bp and heart rate. When you cut down on sugar, your ldl cholesterol will decrease by 10% and triglycerides will reduce by 20-30%. And your risk of heart attack will reduce manifold.

2.&nbsp;Your weight fluctuations will be gone

With the exception of fruits, sugar is mostly present in processed or high-carb foods that contain loads of other unwanted constituents like fat etc.

So when you quit sugar, your body has to no longer worry about those unwelcome calories and your weight will stop moving right and left across the scale.

3.&nbsp;Digestion will become efficient

When you quit sugar, the digestive system becomes more efficient. Since your stomach and intestines have to no longer worry about those difficult to digest processed foods, their abilities and functioning improves. Even your colon begins to work better, may be you take more trips to the restroom, so things get even more on track.

4.&nbsp;No more acne troubles

Sugar triggers acne troubles. When you cut it down, you will no longer be troubled by those zits that dampen your looks. Your skin will actually clear up, cracks will disappear and you will get a healthier skin.

5.&nbsp;You will no longer have sweet craving

With sugar, there is a huge negative, as you enjoy sweets, you crave for more sweets. But if you quit sugar, slowly you will begin to avoid foods that contain sugar and as a result, whenever you will eat anything that has sugar, it will taste over sweet and you will not be able to have large portions. This means no more cravings for sugar!

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5 Wonderful Things That Happen to Your Body When You Quit Sugar!

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