As we all know that IVF stands for In vitro fertilisation. It is a method of stimulating the ovaries in a female body, to release an ovum (egg), which is taken out of the body and fertilised artificially in the laboratory with the help of a sperm. After this, the embryo is transferred back to the uterus where it grows and develops naturally.

Understanding the Procedure

The doctor attempts to have complete control over your menstrual and ovulation cycles, so as to know the correct time of the month when you ovulate. This includes, charting basal body temperatures, hormonal therapy drugs etc.
Frequent blood tests, ultrasound will be required to map the progress of ovulation.
Injections, drugs will be prescribed in required dosage to stimulate the ovaries.
During this time, the doctors will monitor the growth of oocytes (eggs).
After a suitable growth of the oocytes follicles, the eggs are retrieved for artificial insemination. (Fertilisation with the use of sperm cells in the laboratory).
After the successful fertilisation, the embryo is transferred back to the uterus.
Can IVF have side effects?

As a side effect it has a major chance of multiple pregnancies. People intending to have just one child, may not be mentally or economically prepared to take the responsibility of more than one child.
The drugs and medicines used throughout the IVF procedure may create hormonal complications in the long run. It bears a risk of ovarian hyperstimulation syndrome, if the mother has to go through the cycle multiple times.
But it offers a number of benefits too...

IVF increases the chance of pregnancy by a large percentage. It is one of the most successful methods of boosting fertility and pregnancy.
Couples, who have repeatedly failed to bear children naturally, can opt for this treatment to produce their own offspring.
In case the couples are completely infertile, donor eggs or sperms may be used in the process. However, in that case, the offspring will not bear the DNA of both parents.
IVF can greatly reduce the chance of surgery on the fallopian tubes.
IVF also provides an opportunity to choose the healthiest embryos before implanting it back in the uterus. A procedure, known as the pre-implantation genetic diagnosis, determines the presence of any abnormal genes or other chromosomal absurdity.
The procedure of IVF has a very high success rate and with technological advancements in the field of medicine, it has also become much safer.
IVF allows women, who go into premature menopause, to be able to bear a child. This treatment is mostly for women who decide to experience motherhood at a slightly older age.
IVF allows same sex partners and single women to bear an offspring.
It is extremely helpful for women who have their fallopian tubes damaged, blocked or surgically removed.

IVF - 9 Benefits You Must Know!

The fallopian tubes are not mere passages for the egg to travel from the ovaries to the uterus. It is here that conception occurs and hence healthy fallopian tubes are essential for the fertilization of an egg. 

Damaged fallopian tubes are the most common cause of infertility. This damage can fall under three categories. 

 Blocked fallopian tubes
 One blocked and one open fallopian tube
 Tubal scarring

The third is usually an effect of pelvic infections or natural healing after a pelvic surgery. Sadly, in most cases, this condition is discovered only after infertility has been diagnosed. Other causes of fallopian tubal scarring include:

 Stds such as chlamydia trachomatis and neisseria gonorrhea
 Adhesions caused by ruptured ovarian cysts
 Appendicitis
 Peritonitis
 A history of ectopic pregnancies

Fallopian tubal scarring has no recognizable symptoms. Chronic pelvic pain is the only known symptom of this damage and that too can be seen only in severe cases of tubal scarring. On diagnosing infertility, your doctor will perform one of these tests to determine the condition of your fallopian tubes.

 Hysterosalpingogram: this is a type of x-ray. Your doctor will open the vagina with a speculum and inject a liquid into the uterus with the help of a catheter. If the liquid does not pass through the fallopian tubes, it is said to be blocked. This however, does not say much about tubal scarring.
 Laparoscopy: a small incision is made below the belly button and a slim, flexible tube with a camera is passed through the incision. This gives your doctor a clear view of the condition of your fallopian tubes. A laparoscopy can also be used to rule out other causes of infertility such as endometriosis or blocked fallopian tubes. 

Treatment for infertility caused by tubal scarring is of two types:

 Surgery: this is suggested in cases where tubal scarring is minimal. Depending on the intensity and placement of scar tissue, your doctor may decide to perform one of many types of surgeries. He may choose to remove the scarred section of the fallopian tube, create a new opening (in case of blockages) or rebuild the damaged edges of the fallopian tubes.
 In vitro fertilization (ivf): women with badly scarred fallopian tubes usually have poor chances of conceiving naturally. Hence, ivf is the preferred treatment route. However, your doctor may still advise you to undergo surgery and remove the damaged tubes prior to ivf to prevent the tubes from filling with fluid.

Tubal Scarring and Infertility

Women undergo menopause in their 40s and this is primarily known as the age after which they can't bear children in their wombs any more. The ability to develop and maintain a healthy pregnancy wanes as a woman crosses the age of 30, which according to research is the optimal time for a woman to become a mother.

The body undergoes changes as it gets older and women slowly start losing the perfect conditions for pregnancy. However, with the rise of the IVF treatment for infertility, a great number of people are choosing to embrace parenthood at a relatively advanced age. However, the question is, can the same IVF treatment prove effective for a woman after her menopause?

The answer is yes. There have been several instances where a woman past menopause has been implanted with a fertilized egg and has been able to conceive a healthy offspring from the same. However, such an IVF treatment is much more complex and can require a lot of external hormonal treatments on the side as well.

How can IVF help menopausal women?
Women, who have gone into menopause more than 6 months ago, require additional care to achieve pregnancy through IVF. The uterus is usually shrunken in such people and the endometrial lining also develops a resistance to estrogen. Several cycles of estrogen treatment are needed for such women to achieve a healthy pregnancy.

Most doctors suggest at least a couple of months of estrogen and progesterone treatment prior to taking the actual IVF treatment. However, there is no guarantee that the same will be effective in every case.

By any chance, if the menopausal woman chose to store her eggs prior to her menopause, she can get those eggs fertilized and implanted after menopause, using the IVF method, in order to achieve a healthy pregnancy. Through, this procedure, the woman can not only become pregnant after menopause but can also ensure that she is the biological mother of the child who would be born.

At any rate, it is best to undergo the IVF treatment before menopause, as this improves the chances of conceiving. The hormonal treatments are often easier and most women can completely forego the progesterone and estrogen supplementation in such a case. This will not only reduce the time required to complete the treatment but will also significantly reduce the cost that the parents have to bear.

Can IVF Help Menopausal Women Get Pregnant?

When a childless couple is not able to conceive, there are myriad paths that the couple may follow to obtain a solution. If IVF does not help the couple, then they can go in for surrogacy. In this method, another lady conceives, carries and gives birth to the baby created by the sperm and eggs of the intended parents. Let us find out more about surrogacy today.

Who can use it?
Surrogacy can be availed by couples who are not able to conceive due to many conclusive reasons including the absence of a womb or the malfunctioning of the same. Also, recurrent miscarriages can be one of the reasons. Further, a couple who has been through IVF or In Vitro Fertilisation implantation failure a number of times can opt for surrogacy.

How does it Work?
Full surrogacy, as it is known, is a process of implanting an embryo in a host body. This embryo is usually created using the egg and the sperm of the parents, or even a fertilised egg that has been donated by a donor, which is then fertilised using the sperm from the intended father. Also, this embryo may be created by using donor eggs and donor sperms. Partial surrogacy is also a method that may be used. When artificial insemination or intrauterine insemination (IUI) is used to create an embryo with the sperm from the intended father and the egg from the surrogate mother, then the process is known as partial surrogacy.

Chance of having a baby with surrogacy
The chance of having a baby with surrogacy depend on various factors. It depends on the ability of the surrogate to get pregnant, as well as her overall health. Before choosing a surrogate, it is important to put her through all the necessary tests to ascertain a good state of health. Further, the age of the egg donor is also a factor in such cases. The success of related procedures like IVF or IUI will also determine the chances of conception through this method. Furthermore, the quality of the elements used by the couple or the intended parents will also make a difference to the process and its efficacy. Yet, the most important factor includes the age of the woman whose egg is being used.

Difference between IVF and Surrogacy
In IVF, the eggs are gathered from the woman and the sperm is taken from her partner before an embryo is created and affixed in the uterus of the intended mother. In surrogacy, it is actually another woman who carries this lab-created embryo through methods like artificial insemination. The sperm may come from the father and the egg may be donated by someone else, in many cases involving full or partial surrogacy.

What is Surrogacy and how it is different from IVF

Egg Freezing, which is also known as mature oocyte cryopreservation, refers to the method through which reproductive potential is restored among women. Eggs get harvested from the ovaries, frozen and in an unfertilized manner and are stored for purpose of using them later on. The egg freezing procedure is recommended for those women, who would like to delay conceiving baby due to various kinds of reasons.

Before the freezing of eggs, it is important to first retrieve the eggs. Let us look at how the eggs are retrieved, followed by the procedure of egg freezing through two different ways.

Retrieval of Egg

Egg Retrieval takes place just like it is done in case of in vitro fertilization (IVF). Women would need to be put under medication for hormones or through injections, which shall lead to the stimulation of ovaries, leading to more eggs getting matured. After this women would receive the necessary medication to stimulate ovulation and then the extraction of eggs takes place through the use of a needle. Specialists perform this whole procedure by putting women under the effect of anesthesia and are also guided by ultrasounds. Once the extraction is completed, the freezing takes place.

There are two different techniques involved in the egg freezing process. They include:

Slow Egg Freezing Method

A substance called cryoprotectant is used in order to protect the biological tissues from getting damaged out of freezing. This slow freezing method of getting eggs freezed relies on low initial concentrations of crytoprotectant. The cryoprotectant in low concentration is introduced when the egg is at a relatively warm temperature and still continues to experience the usual functions of a living cell. Then the cryptoprotectant would spread all throughtout thus fill the egg, hence replacing most of the water inside the egg. The egg is then inserted into a small container made of plastic and ultimately get placed inside a cooling chamber. The lowering of temperature, to around -6 degree centigrade, takes place through injecting very tiny amounts of liquid nitrogen into the cooling chamber. The cooling process is controlled by a computer.

The main purpose of these techniques is to avoid ice crystals from getting formed in the egg. During the spreading of the cryoprotectant, if the ice crystals are still present, they can cause damage to the egg and hence the egg may not survive the process of thawing. Then the temperature is lowered further to around -32 degree centigrade. By this time, the egg s metabolic rate become slow. The container where the egg was placed, is then dipped inside the liquid nitrogen, forming a solid.

Rapid Egg Freezing Method or Vitrification

At the time of rapid freezing method, there is high concentration of initial cryoprotectant whereas the cell remains at room temperature. The egg is unable to stay for long in this temperature and thus gets poured immediately onto the liquid nitrogen. Cryoprotectant spreads at a rapid rate so as to avoid ice-crystal from getting damaged. Vitrification is a very new method for freeing eggs. Recent research has shown that vitrification of eggs largely improves the possibility for survival after thawing and the rates of pregnancy.

Different Techniques That Can Be Used For Egg Freezing!

In vitro fertilization (IVF) is a process of fertilization in which eggs (ova) from a woman's ovary are removed. They are combined with sperm outside the body in a laboratory procedure, and then the fertilized egg (zygote) is transferred to the same or another woman s uterus for a successful pregnancy.

IVF is one of the several assisted reproductive techniques (ART) used to help infertile couples to conceive a child.

Causes of Infertility

Blocked fallopian tubes
Hormonal imbalance
Endometriosis
Women with ovulation disorder
Uterine fibroids
In the man, low sperm count or poor quality sperm
Genetic disorder
Procedures
Two procedures are done to gain access to ovaries

It involves inserting the needle through the vagina (transvaginally). With the help of an ultrasound machine, the physician guides the needle to the location of the ovaries
In the other procedure, called laparoscopy, a small thin tube with a viewing lens is inserted through an incision in the navel. This lets physician to see inside the patient, and locate the ovaries.
Method
Without additional techniques, the chances of pregnancy would be extremely small. The additional techniques used in IVF include-

Ovarian hyperstimulation- Stimulation to induce development of multiple follicles of the ovaries.
Final maturation induction- Induction of final oocyte maturation is performed, generally by an injection of human chorionic gonadotropin (HCG), when the ovarian follicles have reached a certain degree of development. This is known as the "trigger shot  
Egg and sperm preparation- Semen is prepared for fertilization by removing inactive cells and seminal fluid in a process called sperm washing. An oocyte selection may be performed prior to fertilization to select eggs with optimal chances of successful pregnancy. 
Co-incubation- Eggs are removed from the woman and placed in one of the fallopian tubes, along with the man's sperm. This allows fertilization to take place inside the woman's body. Therefore, this variation is actually an in vivo fertilization, not in vitro.
Embryo culture- The main durations of embryo culture are until cleavage stage (day two to four after co-incubation) or the blastocyst stage (day five or six after co-incubation)
Embryo transfer- The number to be transferred depends on the number available, the age of the woman and other health and diagnostic factors. Embryos are transferred to the patient's uterus through a thin, plastic catheter, which goes through her vagina and cervix.
Aftercare
After the IVF procedure is performed the woman can resume normal activities. A pregnancy test can be done approximately 12-14 days later to determine if the procedure was successful.

Risks

Multiple pregnancies
Ectopic pregnancy
Ovarian rupture, bleeding
Infections
Complications of anesthesia

In Vitro Fertilization - Quick Facts!

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