The Interstitium is a network of tissues in the lungs. It supports the functioning of microscopic air sacs in the lungs, known as Alveoli. Tiny blood vessels travelling through the interstitium help in exchange of gases between blood and air. In ILD or Interstitial lung disease, this important function of the lungs is disturbed. This can lead to ILD, including Sarcoidosis.

In general, the symptoms of ILD include shortness of breath, dry and non-productive cough and unexplained weight loss.

Causes Of Interstitial Lung Disease

It is estimated that regular exposure to irritants through inhalation, at work or otherwise, can precipitate ILD. Bacteria, Viruses, and Fungi are known to cause Interstitial Pneumonias. The following irritants can cause ILD:

  Silica dust
  Asbestos
  Coal dust and other dusts, such as those inhaled during working in mines
  Talc
  Bird proteins (such as Chicken or Pigeon food)
  Grain dust inhaled from farming

Drugs such as Amiodarone, Nitrofurantoin, Bleomycin etc. may also cause Interstitial Lung Disease. However, a fair chunk of the causes of Interstitial Lung Disease are unknown.



About Sarcoidosis

In Sarcoidosis, there is growth of tiny inflammatory cells in different organs of the body, such as the Lymph nodes, Skin, Eyes and the Lungs. Lungs are the most common organs which Sarcoidosis affects.

Symptoms of ILD and Sarcoidosis

  Symptoms may include Fever, Fatigue, Shortness of breath, Weight loss, Persistent cough, Swollen lymph nodes, Chest pain, Wheezing etc.
  There may be reddish-purple bumps on shins or ankles, sores on nose, ears and cheeks, growth of nodules under the skin, etc.
  The patient may have Blurred vision, Eye pain, Severe redness and Sensitivity to light.
  A patient may also suffer from Chest pain, Shortness of breath, Fainting, fatigue, Irregular heartbeats, Palpitations, Swelling due to Accumulation of Fluid, etc.

Treatment of ILD and Sarcoidosis

  Antibiotics for Interstitial Pneumonia condition
  Corticosteroids or Immunosuppressants for skewed immune response
  Oxygen inhalation for low oxygen level in body due to ILD
  Antioxidants to reduce the rate of decline in lung function.

Sarcoidosis

  Though there is no cure for this disease, a patient may be treated through medicine if the disease starts affecting the functioning of other organs.
  The patient may be given Corticosteroids to Suppress Inflammation.
  If the condition is worse, the patient may also be given Immunosuppressants and other medicines to overcome specific organic problems.

ILD and Sarcoidosis are common diseases nowadays due to increasing pollution all around. In case of any of the symptoms of ILD and Sarcoidosis show up in a patient, it is highly recommended to get advice from an experienced Pulmonologist. The treatment is mostly antibiotic-based, and curbs the infection out of the body. The sooner the treatment can start, the better it is.

ILD And Sarcoidosis - Causes, Symptom And Treatment Of Them!

Vitiligo is a skin condition that causes loss of pigmentation of the skin. Melanocytes, the pigment cells, within the skin are destroyed. This causes these parts of the skin to lose color and turn pale. It might affect different parts of the body including the arms, legs, face and even genitalia. It can affect a person of any age, ethnicity or gender.

Causes
The exact cause of vitiligo is not definitively known. However, there are a number of risk factors that might contribute towards the condition. These include-

Autoimmune disorders- Vitiligo might be a result of an autoimmune disorder where the overactive immune system destroys the pigment cells of the skin.
Exposure to Chemicals- Exposure to certain chemicals can increase the risk of vitiligo by causing depigmentation.
Hereditary factors- There might be a genetic pre-disposition towards vitiligo. Though a person can exhibit symptoms of the condition at any age, it is most commonly found to manifest itself around the age of 20 years.
Symptoms
Vitiligo may start with a simple spot of pale skin but over time, this spot expands and turns paler until it is white in color. Irregular in shape, the edges of these spots may inflame and cause itchiness.

Treatment
The treatment of vitiligo will be determined by a number of factors such as the number and the extent of the white patches and where they are located. Vitiligo treatment includes cosmetic, medical and surgical methods.

Cosmetic Treatment- Cosmetic and skincare products such as sunscreens, dye or makeup can help relieve and hide signs of the condition.
Medical Treatment- Oral medication or medicated ointments may be prescribed to treat Vitiligo. Photochemotherapy which involves the use of PUVA rays to induce re-pigmentation may also be prescribed. If the condition has spread to a considerable extent then the physician might advise that the color from the remaining areas of the skin also be removed in order to match the affected areas.
Surgical Treatment- Surgical treatments are at times prescribed which involve skin grafting or tattooing. This is usually prescribed for those with small patches of affected areas.
With ongoing and extensive research being conducted on this skin condition, we will in the near future be able to both understand and treat it better.

Vitiligo - What Causes It and How Can It Be Treated?

Varicose veins are superficial, swollen, enlarged and twisting veins, often appearing dark purple or blue on the feet and legs. The condition occurs when blood through the veins flow in the wrong direction and starts accumulating.

Although varicose veins is not a serious condition, you should seek treatment if it causes symptoms like swelling and pain in the extremities. In severe cases, where a varicose vein ruptures or develops to form skin ulcers, your doctor may recommend laser treatment.

Can laser treatment cure varicose veins?

Laser surgery can effectively treat varicose veins. The procedure involves using a high-intensity beam of light to reduce enlarged, bulging veins that are observed usually on the calves or thighs.

How does the procedure work?

The heat emitted from the laser damages a vein, which causes scar tissues to form. This scar tissue shrinks and closes the vein. A closed vein gradually loses its source of blood and dies. After some time, usually in a year or two, the vein disappears on its own.

Two types of laser surgery are performed, namely  

  Simple Laser Treatment   This is done on the outer layers of your skin. It can cure small varicose veins and spider veins under the skin surface. Normally, more than one session, scheduled every 6-12 weeks is needed.
  Endovenous Laser Treatment   This particular procedure is used to cure large varicose veins that appear on the legs.
The steps of the procedure are as follows  
  Your healthcare provider will administer local anaesthesia to numb the area. You may be provided with an eyeglass to protect your eyes
  The surgeon will make a small incision on the skin and pass a laser fibre through a catheter into the veins while closely monitoring the vein on a screen
  As he/she pulls out the catheter, the length of the vein will heat up and shrink, and eventually close

This outpatient procedure is less painful than stripping and litigation. It has a shorter recovery period and can be performed under local anaesthesia or mild sedatives.

What to Expect

After the laser treatment, you can walk around without much complication. The recovery period is typically brief. You can expect to return to your daily activities following simple laser surgery. However, you might need to wear a compression stocking for a week or so after the endovenous laser procedure.
You may notice redness, bruising or burns on the skin after the treatment. That is only normal, so you need not worry. Do follow up with your doctor to see if the vein has closed.


Laser Treatment For Varicose Veins!

The period around the age of 45 to 50 is very delicate for most women as many changes occur within the body. The changes occur due to menopause or a cessation of the menstrual cycle for a period of at least 12 months or so. Along with a host of physical changes, post-menopausal women tend to suffer from mental problems as well. Some of the factors could be physical changes such as a decline or stop in hormone productions while some of them are psychological effects as well. Some of the common mental problems faced by women are mentioned below:

Depression: This is by far the most common mental disorder and affects women while they are going through the process of menopause. After a few years, post-menopausal women tend to recover from this or the symptoms at least taper off. It is estimated that almost 20% of women undergoing menopause suffer from this problem, although the risk of depression is much higher if you have prior history of it.

Sleep Disorders: This can be described as not only a mental disorder that affects women but also a symptom of menopause. Sleep disorders can range anywhere between disturbed sleep, insomnia or sleep apnea (breathing difficulty while sleeping), especially in older women. Women undergoing menopause may suffer from this due to hormonal changes which result in hot flashes. These can wake you up in the middle of the night almost daily.

Schizophrenia: This is a serious mental disorder and is mostly noticed in women who have a prior history of the disorder. This condition is characterized by delusions and a detachment from reality which often pushes the person to act on their inappropriate imaginations. Schizophrenia usually manifests itself in young adulthood and peaks again at the age of around 45 to 50. If you had episodes of schizophrenia in your early adulthood, then it may resurface during menopause, although most women do see a subsiding of symptoms some time after menopause has occurred.

Panic Disorder: Women tend to experience this problem, during or even after menopause, as a new disorder that suddenly develops. This can be quite disruptive in your life. Also, if you have a history of this disorder, menopause may trigger it to show up again.

Obsessive Compulsive Disorder: This disorder is another mental health issue that can cause you to be overly obsessive, more so among menopausal women. If you already have had OCD in the past, menopause can trigger a relapse or a bad episode.

Bipolar Disorder: In this case as well, menopausal women have a higher tendency for a relapse or the start of a bad episode if they already had even mild signs of it.

Mental Problems In Menopausal and Post-Menopausal Women!

Seasonal changes can be very exciting for most people. Each season brings with it a new set of colours and nature takes a new turn. However, for people with seasonal allergies, a seasonal change also comes with a set of allergies. From skin rashes to wheezing to breathing difficulties, the list of symptoms can be quite long. Asthma is the most common problem, and the attacks can be quite bothersome with wheezing attacks and breathing troubles.

With advancements in the field of medicine, there is a lot of relief for asthma patients. A little understanding on how asthma attacks happen will help in understanding how to control it. Asthma is an allergic reaction caused by narrowing of the airway with thick mucus, which makes breathing difficult. During an attack, the person can have a dry cough, face shortness of breath and wheezing.

Asthma is often triggered or worsened by some factors, and being aware of these can help prevent or manage an attack:

Common allergens like pollen, mites, ticks, furs of animals, bird feathers, specific foods (peanuts, milk products, eggs, etc.) and mold spores appear during change of season.
Environmental chemicals like cigarette smoke, car fumes, dust, etc., can also trigger an attack.
Attacks of cold or flu can lead to an asthma attack.
Workout during cold weather can be problematic, but exercise can also help control asthma attacks. Lung function improves sufficiently, but an exercise regime should be drawn up for the patient based on his condition.
Stressful emotions like anger and anxiety can also lead to an attack or make it worse.
Some medications like aspirin, beta blockers, glaucoma drops can aggravate attacks of asthma.
Once you know the triggers, here are some common measures that can help prevent and relieve the wheezing.

The preventers reduce the inflammation in the airway tube and the swelling. While they do not provide immediate relief during an attack, using these in the long term helps avoid attacks. These are low-dose inhaled corticosteroids such as beclomethasone, fluticasone, and budesonide. Doctors would advise their usage even when there are no symptoms, as asthma attacks can be triggered when they are not taking these medications for a while. Newer drugs include leukotriene antagonists like montelukast and zafirlukast. Relievers are used for symptom relief and include Salbutamol (short acting) and Salmeterol/Formoterol (long acting). Peak flow meter may be useful in acute attacks, wherein the peak flow rates can be reduced.
A good strategy is to use preventers regularly and rely on relievers during an attack. The first one helps build resistance and so reduces the incidence of attacks. Reach out to a doctor if a severe attack ensues (lasts more than 3 hours).


Tips to Control Allergy Driven Wheezing this Season

Hepatitis C is a Viral Infection That is Little Talked About, But Can Be As Dangerous As Hepatitis B

Most people have head or what became in the 1980s and '90s the dreaded AIDS virus. With time and the availability of medicines, it ceased to be a killer. However, the knowledge of it helped stem its spread. Most people, unfortunately, don't realize that hepatitis C is also a killer, simply because not much has been said about it. In fact, it is also a virus, but is 10 times more infectious than HIV.

Hepatitis C is transmitted through the blood, and is usually passed on to women through infected needles and sex. At-home glucometers are often shared, or sometimes a woman's own lifestyle or her partner's lifestyle before marriage may put her at risk, because the virus can stay in the blood for years. It is also transmitted through blood products, like in the case of a transfusion, though in the case of pregnant women, this is not so common.

The dangers
The virus affects 1 in every 100 people in India, while globally 180 million are infected with it. Sometimes, it may just pass through the body, like many other viruses do, but sometimes, it can remain. If detected quickly, within six months or so, cure rates are high. the problem is that it is often not easy to detect, as symptoms resemble those of a regular seasonal viral infection: fatigue, nausea, loss of appetite. If it remains in the body, becoming chronic, then it may progress to liver disease. But the hepatitis C virus (HCV) doesn't have to be a killer. You can conquer it with these moves. 

What you should do before
A number of couples who come to me have planned pregnancies-they opt for a baby, rather than the baby just 'happening' to them. This not only helps family planning, but it also helps us rule out infections or treat them if present. Usually, in the first trimester, your gynecologist will ask you to do a simple blood test for HIV, hepatitis B and C. In the case of a planned pregnancy, visit your doctor beforehand and ask if you need to take these tests before you conceive. However, there is no vaccine for HCV yet.

What you should do after
If a woman find out in the first trimester that she is hepatitis C positive, there's nothing much that can be done, as anti-viral medications cause birth defects, so a mother can only be put on them after delivery. She is advised to continue the pregnancy. A baby's chance of acquiring the infection in utero is between 5 and 7%. While this is not high, parents may like to avoid the risk. However, co-infection with HIV (if the mother is HIV positive) pushes the risk up to 19.4%. The pregnancy itself will not be hampered by the HCV infection. Nor does the risk of transmission to the child have anything to do with the mode of delivery-either vaginal or C-section. In India, there is little data on HCV transmission from mother to child. However, once the baby is born, the pediatrician may not do an immediate test to check for the virus, as it generally clears out from the baby's system in a year or so. Testing may only be done at 18 months.

Hepatitis C: Can Be as Dangerous as Hepatitis B

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