Photodynamic therapy or PDT is a relatively new and non-invasive treatment for non melanomaskin cancer. It is mostly used in cases where the cancer is superficial and has not spread too deep. PDT is used mostly to treat Actinic Keratoses on the face and scalp, Basal cell carcinomas, Bowen s disease, as well as other conditions such as head and neck, mouth, lung and gullet cancer.

How does it work?
This treatment involves the use of a drug known as photosensitize or a photosensitizing agent with a specific type of light. When the photosensitizing agents get exposed to a light of a specific wavelength, a form of oxygen is produced, which eliminates nearby cancer cells. Every photosensitizer gets activated by the special light. The wavelength of the light determines how much it can penetrate into the body.

Process of Photodynamic therapy
Skin cancer is cured by PDT in several steps. The first step involves the injection of a photosensitizer into the patient s bloodstream. The blood cells absorb the agent all over the body, but in the cancer cells, it stays for a longer duration. Within 72 hours after the injection is given, the skin is exposed to light. The photosensitizer agent present in the cancer affected cells absorbs the light. An active oxygen form gets produced, which kills the cancer cells.

Other than killing the cancer cells directly, PDT uses two other ways to destroy cancerous tumors. The blood vessels in the tumor are affected, which leads to its death. The immune system also gets charged up and activated for fighting the cancer cells.

The light used for PDT is usually in the form of a laser. LEDs are also used to treat tumors present on the surface of the skin. The primary photosensitizing agent used in PDT is called porfimer sodium or Photofrin.

PDT can be undertaken in the outpatient department in a hospital. After taking the treatment, you have to keep the cancer affected area of the skin dry and covered for 36 hours. The area should be treated with care while showering. In case of thick skin lesions, repeat treatments are required within 4 weeks.

When is PDT used for skin cancer
PDT can be undertaken instead of surgery for treating basal cell cancer, Bowen s disease and actinic keratosis. PDT is used in cases where surgeries are required. It is used to treat large skin cancers, which are not very deep and in the case when several cancers develop in an area. For many skin conditions, PDT is a better remedy than undergoing a surgery.

Advantages of PDT

    There are no long term side effects.
    The process is less invasive compared to surgery.
    A very short time is taken for this therapy to be undertaken.
    The process can be repeated several times in the same area.
    Very less scarring takes place in the affected area.
    The cost of this procedure is lesser than surgery.

Treating Skin Cancer with Photodynamic Therapy

Do you know not all foods can be consumed on an empty stomach? So, it is imperative that you should be aware of such foods and restructure your breakfast menu accordingly. Here is a list of foods to avoid on an empty stomach. 

Stay away from the following foods when you eat after a considerable gap

Citrus fruits: Citrus fruits contain fruit acids. When these acids enter an empty stomach, they can lead to heartburn. Hence, if eaten after a prolonged period post meal, a person is at risk of gastritis and stomach ulcers.
Soda: Consuming cold soda drinks on an empty stomach may cause damage to the mucosal membrane while reducing blood flow to the stomach. This may lead to a slow digestive process and difficulty in the abdomen.
Spicy foods: Spicy foods are known to cause irritation and damage to the digestive tract, and are especially not recommended for people who suffer from acid reflux issues since very spicy food leads to consequences such as acid reflux in the food pipe.
Cucumber and other green vegetables: Green vegetables and cucumber are rich in amino acids. If consumed on an empty stomach it may very well lead to pain and bitterness in the upper abdomen.
Tomato: Tomato is a fruit containing high levels of tannin. Tannin causes acidity in an empty stomach and leads to consequences and appearance of gastritis if frequently consumed in such a manner.
Fermented milk products: Fermented milk products such as yogurt typically come with loads of health benefits being full of probiotics. But if consumed on an empty stomach it can interfere with the balance of healthy bacteria as the hydrochloric acid produced tends to be destructive.
Sweets: Items such as candy or sweetmeats contain high levels of sugar and cause a sudden and sharp surge of insulin levels in the blood. Over a long period, this has a bad effect on the pancreas.
Products containing yeast: Edible items such as biscuits, puff pastry, vinegar and beverages such as beer and wine contain yeast which can significantly irritate the stomach and cause bloating.
So, be a little conscious and avoid consuming these items on an empty stomach since a little effort goes a long way. In case you have a concern or query you can always consult an expert & get answers to your questions!

Empty Stomach - 8 Food Types That You Must Avoid!

Umbilical hernia refers to a condition where your intestine protrudes through the opening of the belly button. This condition generally affects infants, but some people may suffer from it in adulthood as well. Umbilical hernias are common but do not cause any health issues in most cases. However, in some instances, the disorder leads to problematic symptoms.

Symptoms of umbilical hernia:

If you or your child suffers from the symptoms mentioned below, you should seek treatment.

  Pain
  Nausea/vomiting
  Discolouration and swelling at the region of the hernia

If one or more of these symptoms appear, seeking treatment at the earliest is necessary to avoid further complications.

Complications from umbilical hernia:

Even though complications from the disorder are rare in infants, they are not unheard of. The most common complication occurs when the portion of the intestine protruding from the belly button is trapped. In such a case, blood supply to this region is cut. This can lead to tissue death or gangrene. The infection slowly spreads to the rest of the digestive system, causing a life-threatening situation.

Adults who have umbilical hernia are more likely to suffer from complications of the condition.

Treatment for umbilical hernias:

Treatment differs based on the age of the patient. In most infants, the umbilical hernia does not produce any symptoms. In fact, such hernias typically disappear on their own after a year or two. A doctor may also be able to push the hernia in during a routine check-up. However, you should not try to do this yourself.

When is surgery needed for an umbilical hernia?

An infant requires surgery for the hernia if he/she experiences the following traits-

  Pain
  The hernia has a diameter larger than half an inch
  The hernia is large and does not decrease in size in the first two years of the child s life
  Does not disappear even when the child reaches the age of four
  The external portion of the intestine sticks out and gets trapped.

However, in the case of umbilical hernias affecting adults, a doctor will always recommend surgery to avoid possible complications arising from the disorder.

How is the surgery performed?
For both infants and adults with an umbilical hernia, the surgical procedure remains the same. The surgeon makes a small incision at the base of the belly button. The doctor uses this opening to return the external part of the intestine inside the abdominal cavity. Once this is complete, the doctor stitches the incision.

In adults, a supportive mesh is also used to ensure that the intestine does not protrude once more through the belly button.

Laparoscopic hernia repair is suitable for all types of a hernia such as an umbilical hernia. Just like an inguinal hernia, A camera is placed into the abdomen through the muscles. Two small incisions are made for the operating instruments to get through. This is followed by the cutting of the tissue that is placed between a hernia and the intestine. The hole thus gets exposed. Through one of the laparoscopic ports, the hernia mesh gets rolled and is placed into the abdomen. A hernia is then pulled up and the mesh gets secured with 4 sutures. A special device is used to fix healthy muscle.

Umbilical Hernia - Everything You Should Know About It!

Get off the mobile and go outside - Are these words being heard more commonly nowadays, than at any other point in time in life? The answer could be frighteningly real as humanity has just stepped in one of the newest forms of a psychiatric disorder. What's worse is that the medical world is divided whether if this should be considered as a disease and separate field to be dedicated to it or simply pass it off as a generation growth that the future has to embrace. 

Let us look a little deeper about the disorder and the serious nature that it weans.

What is internet & phone addiction?
Only recently did Internet addition and phone addition become part of the diagnostic and statistical manual of the mental disorder - Meaning that internet addiction is now effectively considered a psychiatric disorder and there are chances of identifying and treating it using medically approved means. As the name suggests, internet addiction and phone addiction means that the person is using his creative and designated time on the medium when he is no longer required to. Simply put it becomes an obsessive habit on the part of the person to look into the phone and use the internet as a routine activity. Long-term addiction can lead to many psychological factors such as withdrawal symptoms, depression, and general loss of awareness about the surroundings. For most people, the syndrome can be an underlying factor of an even more severe health condition that the person is trying to mask by whiling away his time with the internet and the mobile. Across the people who get affected by it, the common traits are the internet gaming and social media.

The addiction in today s world:
The velocity of the disorder is yet to take on the world. As of now only two countries- South Korea and China have identified the disorder as a disease and treatments are administered. Europe and United States have just categorized it as a disorder and research is being done on it. The general treatment plan that exists now aims to understand the patient first. The psychiatric treatment tries to successfully make a minor bridge between the user and his addiction. From practicing different time of using the internet to suggesting new schedules and goals, the person can be slowly be eased backed into the society. The purpose of the psychiatric treatment is not to block the internet/ mobile usage completely but to limit them. A person is educated to get his satisfaction in other forms like relations ships, outdoor activities than to depend on the internet. Apart from it some depression reducing drugs can also be had at the insistence of the psychiatrist.

Medical Possibilities
Professors argue that Internet addiction and mobile addiction is not exactly a disease. It simply determines an underlying medical condition of a person that needs more treatment. Though still in its early stages the medical world has made it clear that its contribution towards these mental addictions would increase by massive miles within the turn of the decade.

Internet & Phone Addiction - Can It Be A Sign Of A Medical Condition?

Autoimmune disorders are one of the least understood disorders in the whole of medical science. Systemic Sclerosis is also an autoimmune disorder in which the skin undergoes changes in texture and characteristics. 

However, the changes are not confined to the skin alone. It can affect blood vessels, muscles, digestive system, heart, kidneys, as well as the lungs. It typically affects people in the age group of 30 to 50 years, but the good thing is that doctors can diagnose this at any age. 

It has been observed that more women fall prey to this disorder than men. The severity of symptoms may also vary from person to person. Nevertheless, the real cause of worry is the progressive nature of the disease. Due to this, it is, in fact, sometimes referred to as Progressive Systemic Sclerosis. 

Causes of Systemic Sclerosis 

It is an autoimmune disorder in which the immune system attacks the skin and precipitates the problem. The attack by Immune System precipitates increased collagen production in the body, which accumulates in the skin tissue. This leads to changes in characteristics and the appearance of the skin. 

Symptoms of Systemic Sclerosis 

Systemic Sclerosis affects only the skin in the early stages. It may lead to thickening of skin and development of shiny areas around bony areas, such as nose, mouth, fingers etc. However, as the disease progresses, it may limit movement of these affected areas. So one may have a problem in opening the mouth, parting fingers etc. 

Other symptoms are: 

  Loss of hair 

  Deposit of lumps under the skin 

  Blood vessels under the skin getting dilated 

  Pain in the joints 

  Breathing difficulties 

  Dry cough 

  Constipation 

  Diarrhea 

  Swallowing difficulty 

  Reflux of food from esophagus 

  Feeling of bloating after taking meals 

In addition to the above, one may also sometimes experience spasms in the blood vessels of fingers and toes. Legs and hands may turn blue or white if a person is undergoing emotional stress or is in extreme cold. This is also known as Raynaud s phenomenon. 

Risk Factors

Though the causes of the disease are not yet known, there are some risk factors which can make a person susceptible to this disease: 

  If a person is undergoing chemotherapy with certain drugs like Bleomycin or are exposed to stuff like silica dust, organic solvents etc., one may become susceptible to this disease. 

  Women are more prone to acquiring this disease than men. 

  If a person is a Native American or an African-American then too he/she is more susceptible to this problem. 

Treatment of Systemic Sclerosis 

Systemic Sclerosis can t be cured, but its symptoms can certainly be reduced to some extent. So, treatment is specific to symptoms one is experiencing, and may include using the following: 

  corticosteroids 

  immunosuppressants 

  nonsteroidal anti-inflammatory drugs 

  blood pressure medication 

  aid to resolve breathing difficulty 

  physical therapy, light therapy etc. 

The fact that this disease really can t be fully cured makes this a pretty scare disease. Silver lining is that medication and other treatment options are able to suppress most of the symptoms.

Systemic Sclerosis - What Causes It?

The human spine has 33 vertebrae. However, some conditions can fuse these vertebrae. Ankylosing Spondylitis is one such condition. This disease may also be known as AS or Bechterew's disease. It is an inflammatory disease that can make the spine less flexible by fusing the vertebrae of the lower back together. In some cases, it can also affect the rib cage and make it difficult to breathe. This disease typically affects more men as compared to women. Most patients begin showing symptoms in early adulthood.

Ankylosing Spondylitis affects the sacroiliac joints. These joints are located just above the tailbone. It causes inflammation of the spinal bones that in turn cause pain and stiffness. With time, this inflammation spreads to the entire spine and the vertebrae begin fusing together. This can make movement difficult and painful. In severe cases, it can also lead to the development of a hunchback. This disease also affects the other tissues of the body. For example, it can affect other joints and aggravate arthritis or affect organs such as the kidney, heart, lungs, and eyes.

A specific cause has not yet been identified for Ankylosing Spondylitis. However, studies show that genetic factors can be a trigger. In particular, the presence of the HLA-B27 gene increases a person s risk of developing symptoms pertaining to this condition. However, it is important to note that merely the presence of this gene does not make Ankylosing Spondylitis inevitable. Other genes that are associated with this disease are ARTS1 and IL23R. These genes influence the functioning of the immune system. While it can affect people of all ages, adults are at a higher risk of suffering from this condition.

In many cases, the initial inflammation of the spine is due to a bacterial infection of microbial infection. Though the infection itself may be treated and cured, it may cause the immune system to react and trigger inflammation. Once activated, if the immune system cannot be turned off, this inflammation will continue and can trigger Ankylosing Spondylitis. In each case, the disease presents a unique pattern of progression.

There is presently no cure for this condition, but with an early diagnosis and treatment, the symptoms can be managed and progression can be slowed. This treatment usually takes the form of medication to relieve pain, inflammation and discomfort and physical therapy. Surgery cannot be used to treat Ankylosing Spondylitis but in cases where it has caused severe joint damage, surgery may be advised to replace the damaged joint.

Ankylosing Spondylitis - What Are The Causes?

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