SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

Nephropathy is also known as renal disease. It is any type of damage or disease relating to the kidneys. Though not everyone with diabetes has nephropathy, however, diabetic nephropathy can cause kidney failure.

How does diabetes affect the kidney?
Kidneys are responsible for taking waste out from your blood. They have a lot of tiny blood vessels to do this. High blood sugar may kill such blood vessels. Once these blood vessels are destroyed, the kidneys may not function as well or it may even lead to kidney failure.

What increases your risk of getting diabetic nephropathy?
There are several factors which increase your risk of getting diabetic nephropathy including: \
1. High blood pressure
2. High cholesterol
3. Smoking
4. Being native american, african american or of hispanic origin, for whom risk factors have proved to be magnified
5. If you have family history of diabetic nephropathy

Symptoms and diagnosis:
There are very few noticeable symptoms, which appear when you have diabetic nephropathy, except swelling in your arms and legs. The diagnosis is done by checking for a type of protein in your urine known as albumin, which is not supposed to be there. Getting the diagnosis done early is crucial.

Preventive measures
You can prevent kidney damage by doing the following:
1. Keeping your blood sugar levels under control - keep hba1c &lt; 6-7%
2. Keeping your blood pressure under control in the range of 130/80
3. Eating healthy food
4. Exercising regularly
5. Not eating too much protein
6. Not eating too much salt
7. Reducing smoke or excessive tobacco usage

Medicines for treatment
If you do get diabetic nephropathy, here are some medicines, which can help cure it
1. Ace inhibitors which are also called angiotensin-converting enzyme inhibitors
2. Angiotensin ii receptor blockers (arbs)

Possible complications
1. Blood pressure may rise
2. Triglyceride levels and cholesterol levels may rise.

All About Diabetic Nephropathy

The instance of diabetes are rising day by day. Being a silent killer, it is attacking the young generation secretly and two common impacts of taking modern medicines for diabetes are insulin resistance and various side effects. This eventually has led to a search for alternative methods, which can address the problem of diabetes. Ayurveda plays a vital role in curbing diabetes, if you use it the right way, it can address the root cause of diabetes through proper application of diet, drugs, panchakarma and yoga.

Simple ways to cure diabetes through Ayurveda

Bitter gourd juice: You can take up 30 ml of bitter melon juice every morning on an empty stomach. If you are unable to consume it raw, then you may prepare simple oil-free recipes with it. It is one of the best remedies of diabetes and you can see a lowered diabetes level with consistent consumption of bitter gourd juice.
Ground bay leaf and aloe vera: The mixture of half teaspoon of ground bay leaf, half teaspoon of turmeric and one teaspoon of aloe vera gel can be taken before lunch every day to control blood sugar level.
Fenugreek seeds: Commonly called the Methi seeds, this ingredient can be mixed with a little amount of turmeric along with a glassful of warm milk twice daily to reduce blood sugar problems. You can soak some fenugreek seeds in warm water overnight and chew it on an empty stomach in the morning.
Jamun seeds: The seed powder of Eugenia jambolina, commonly called the Jamun, is very helpful in reducing the blood sugar level. You can have one teaspoon of jamun seed powder followed by a glass of warm water or chew Jamun leaves to prevent the conversion of starch into sugar.
Indian gooseberry: This fruit enriched with high amounts of Vitamin C is commonly called Amla. Having 20 ml Amla juice every day can be prescribed for a diabetic patient. You can also take the amla fruit powder every day to get similar results.
Bark of the banyan tree: If you are suffering from increased levels of blood sugar, then you may consume the decoction of banyan tree bark twice regularly. You will have to take 20 grams of the bark and boil it in 4 glasses of water. When this mixture is reduced to approximately 1 glass, you can consume it after it cools down.
The level and symptoms of diabetes vary among different individuals. Therefore, before you jump on to trying any of these methods, it is recommended to consult an expert who can help you select the most suitable Ayurvedic solution for increased sugar levels.

Diabetes - 6 Effective Ayurvedic Remedies for Treating it!

A rising number of teenage girls in the country are getting affected with Poly Cystic Ovarian Disease or PCOD. Though an advanced menarche has become very rampant these days, there are many young women who are suffering from a delay in menarche which in turn is leading to PCOD as opined by gynaecologists. Obesity and sedentary lifestyle among young people have caused a rapid doubling of PCOD cases in the past five to eight years.

Occurrence and Symptoms:

Gynaecologists report that they get at least 15 fresh instances of PCOD cases, and a considerable number of teenagers aged 16-17 are not getting their menarche. Such patients are recommended to take a strictly balanced diet which will help them to lose weight. Initially, their mothers think that they would experience their menarche in proper time, but some girls are diagnosed with PCOD when taken to a family gynaecologist. Even worse, they could never imagine that their obesity can pave the way for such a grave health issue. PCOD can cause numerous other problems like delayed and irregular menses, rapid weight gain and tremendous difficulty in losing weight, developing acne and blocked skin pores.

Furthermore, it leads to thinning of hair and excessive growth of hair on chest, back and face. Infertility, continual miscarriage, high blood pressure and high blood sugar are also common with PCOD.

Help yourself with the right diet:

There is no proven evidence regarding the cause of PCOD though gynaecologists are of the opinion that some females possess a predisposition to this disease, and it may run hereditarily in the family. You can alleviate your PCOD symptoms to a considerable extent by regulating your diet properly.

Have loads of fruits and green leafy vegetables and try to abstain from dairy products as many experts believe that dairy products are a direct cause of an increase in insulin levels, which can aggravate skin troubles along with other PCOD symptoms. Avoiding red meat and eating lean meat instead will help the condition and reduce the chances of infertility. It is always recommended to avoid hydrogenated and saturated fats, which are normally found in animal and dairy-based food. Try to put a stop to cheese, cottage cheese, clarified butter, pork, lamb, beef, etc. and certain baked products like cookies, cakes and fudges as they will trigger a rise in your blood sugar and cholesterol levels.

The following dietary tips can be helpful with the condition:

High levels of the insulin hormone causes PCOS symptoms like high blood sugar, increased hair growth, weight gain etc. So, refined foods rich in fat and carbohydrates should be consumed in small amounts.
Whole foods in their natural, uncooked form should be consumed fruits, vegetables, nuts, beans etc. These are low glycemic foods that reduce the glucose circulation by insulin.
Intake of salt should be very limited. You should not consume more than 3 grams a day.
Green vegetables have antioxidants. These are good for women with PCOS because they have a high amount of oxidative stress.
Your daily diet should contain at least 30 grams of fiber to improve the digestion process and remove toxins.
Milk and dairy products are best avoided because milk helps to increase the level of testosterone (male hormone) in the body.
Soy products should also be avoided, especially if you are trying to conceive, because they interfere with the ovulation cycle.
Processed fat is harmful but essential fatty acids found in avocado, fish, olive oil and nuts are important for the body.
High levels of male hormones also cause high cholesterol. So foods which have high saturated fats like butter, cream, coconut oil and fatty meat should not be included in the regular diet of women with PCOS.
Protein-rich foods like lean meat, fish, legumes, whole grains are beneficial as protein can stabilize blood sugar. These foods also keep you feeling full and prevent over-eating.
PCOD is such a condition which you can never afford to overlook. If you had been facing any of the common symptoms, then it is probably time to pay a visit to a responsive gynaecologist.

Diet For Poly Cystic Ovarian Disease (PCOD) 

Cough is also known as a sudden reflex in which you have to clear your throat and breathing passage from microbes, irritants, fluids and mucus. You can also call coughing as the rapid expulsion of air from your lungs. Coughing can be both deliberate and involuntary. There are two types of cough which can make you suffer dry or wet. Wet cough is caused due to cold, cold extremities or viral attack. Dry cough is caused due to exposure to pollutants, smoke, environment and also if you have allergy from dust. Cough problems have an effect at your lungs, respiratory tract and immunity system. Ayurvedic treatment is oldest holistic medicine treatment and was developed thousands of years ago in India. Ayurveda promotes good health and can be used effectively for both wet and dry cough.

Ayurvedic remedy for wet cough:
Symptoms for wet cough includes pain in your throat and chest, fatigue and irritability.
1. Using liquorice powder (3 tsp), black peppercorn (1 tsp) and sugary candy (2 tsp) can make an effective natural home remedy. Crush all three ingredients all to form a powder and you should eat half tea spoon of this mixture 4 times a day.
2. Crush a little ginger to make a paste and paste it on a sieve. Extract the ginger juice and add honey (1 tsp). Mix well and heat it till it becomes lukewarm. You should eat 1 tea spoon thrice a day.

Ayurvedic remedy for dry cough:
The causes for dry cough include pneumonia, sinus infections and viral infections in your respiratory tract. Symptoms are fatigue and weak immune system along with an itchy throat.
1. Using almonds, butter and sugar makes for an effective natural Ayurvedic home remedy. Make a paste with 7 almonds (soaked overnight) and add 2 tea spoons of butter and sugar each to the paste. You should mix well and eat it twice every day, at morning and evening.
2. You can also make a paste by mixing small quantity of basil leaves, ginger and honey. Mix well and have 1 tea spoon thrice a day.
3. Take a glass of warm water and add 1 tea spoon each of turmeric powder and carom powder. Mix it well and drink the mixture about two times a day. This is an effective remedy for dry cough.

Ayurvedic Remedies for Cough

HIV or Human Immunodeficiency Virus is a type of immune disorder which attacks the immune system of the body and slowly destroys it overtime. The HIV virus targets the immune system and makes the body susceptible to other diseases. HIV infection can progress to AIDS although it may take up to 10 or 12 years to fully go into the last stage.

Risks and Causes
HIV is a communicable disease which spreads through only the following methods

    It can spread from one person to another by means of unprotected sexual intercourse due to the exchange of bodily fluids.
    The virus spreads if you share drug needles with someone who is already contaminated with HIV virus. It can also occur due to improperly trained medical staff that may reuse syringes although this is very uncommon.
    The HIV virus transmits from the mother to the child during pregnancy through the placenta.
    Any exchange of blood in significant amounts such as blood transfusion from a contaminated patient will result in infection as well although this is very rare.

Any other form of contracting the disease such as through kissing or food is a untrue and only propagates due to ignorance.

Symptoms
The initial symptoms of HIV infection are noticed after a few weeks although it can take a few months to come up as well. The initial symptoms may include
1. Severe headache along with intense pain in the muscles and the joints of the body.
2. Frequent appearances of rashes
3. inflation of the lymph nodes
4. Itchy skin
5. Disorders which stay for sustained periods such as an upset stomach or a cold.

The early symptoms disappear within 2 to 3 weeks without any treatment. The later symptoms might appear after few years (sometimes up to or more than a decade), which will stay. This is usually the time HIV is diagnosed. The symptoms now may also include
1. severe muscle fatigue
2. severe loss in body weight,
3. High fever and recurrent instances of sweating at the night time.
HIV is suspected if the later symptoms tend to last for a long time without any other diagnosable cause.

Treatment
HIV can be treated by means of antiretroviral therapy which reduces the rate at which the virus multiplies. However, there is no cure for HIV as of yet.
Prevention
In order to prevent yourself from getting HIV, you should adopt the following precautionary measures:
1. You should use protection every time when engaging in sexual intercourse and if you are unsure of your partner s HIV status.
2. You should use new blades in barbershops for shaving purposes in order to prevent yourself from HIV as well
3. If you are diagnosed with HIV/AIDS while you are pregnant, to prevent spreading it to your unborn baby, you might immediately need undergo a medical check-up and follow the doctor s advice.
4. Ensure that disposable syringes are used whenever they are being use for medical tests or treatments.

HIV / AIDS - Things You Should Remember About It

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