Most people believe kidneys to be organs solely responsible for the filtration of blood and production of urine. But the truth is that the kidneys perform a host of vital functions in the body which include regulation of blood pressure, blood volume, and blood Ph. Around half of the individuals affected by lupus suffer from kidney problems, and the most affected part is the glomerulus whose function is filtering substances from the blood.

Effects of lupus nephritis on the kidneys
Lupus itself doesn t lead to kidney infection or inflammation. But lupus nephritis, which is the Systemic lupus erythematosus (SLE) that affects the kidneys and the medications used for treating the condition tend to suppress the immune system. It makes the person affected with lupus vulnerable to the infections of various types. It is one of the most severe conditions of that could be encountered by a person wherein the immune system starts attacking various parts of the body as they would tackle a disease.

Lupus nephritis makes the kidney unable to remove the waste materials effectively from the blood. This leads to loss of control over the amounts of fluids regulating in the body. As a result, an abnormal amount of waste can build up in the blood resulting in edema or swelling.

When left untreated, these conditions can cause scarring along with permanent damage to the kidneys and end-stage renal disease. When a person has end stage renal disease, he or she needs regular filtering of the waste products of the body with the help of a machine. In severe cases, a kidney transplant may be required to ensure that at least one kidney is working properly.

Individuals who are susceptible to developing lupus nephritis:
A person with lupus may see the symptoms of lupus nephritis within 5 years and the people aged between 20 and 40 years are most vulnerable to it. In some common instances, it is seen that lupus nephritis is leading to unexplained weight gain along with swelling and puffiness in different parts of the body such as ankles, hands, eyelids, legs, and feet. During the first stages, these symptoms are often ignored which causes worsening of the condition. The urine may also become frothy or foamy with a reddish tinge in it. It is estimated that about 40 percent of children having lupus would develop kidney complications. Lupus nephritis may also cause increased urination, blood in the urine and elevated blood pressure.

If you have lupus, it is imperative to consult with a nephrologist. Testing a sample of the urine can help in showing the problems in the functioning of the kidneys. Your doctor will advise you about the diagnostic tests that can help in determining whether the disease has progressed to severe levels and start with the treatment process accordingly.

How Does Lupus Nephritis Affect Your Kidneys?

The bladder is a hollow storage organ that collects urine from the kidneys and stores it until it can be passed out of the body through the urethra during the process of micturition or urination. It has a thin inner lining of cells called urothelial cells and a thick muscular wall, which exerts pressure to push the urine out of the body.

Causes of Bladder Tumors

In most cases, the bladder tumor develops on the inner layer due to a combination of some of the following factors.

1. Hereditary: A strong family history of cancer predisposes a person to cancer.
2. Gender: Men are 3 times more prone for bladder cancer than women.
3. Ethnicity: White people are more prone for bladder cancer black people.
4. Smoking: Smokers develop bladder cancer 2-6 times more frequently than non-smokers. cigarettes contain toxic, carcinogenic substances which reach the kidney and are stored in the bladder, leading to their damage.
5. Occupational hazards: Some workplaces have a higher likelihood of causing bladder cancers, especially dye and rubber industries. The effects can be damaging, and the person may develop cancers years after the exposure has happened.
6. Recurrent bladder infections: In some people, this can also lead to bladder cancer in the long run.

Types of Bladder Tumor

Depending on the extent of the cancerous spread, it can be of two types:

1. Non-muscle-invasive bladder tumors: The tumor spread is limited to the inner part of the bladder (urothelial cells)
2. Muscle-invasive bladder tumor: The tumor has spread to the thick muscular outer layer. This is more advanced and prognosis is poor compared to the noninvasive type.

The most common and diagnostic symptom of bladder cancer is the presence of blood in the urine, known as hematuria. This will be intermittent and happens whenever the tumor bleeding happens. Other symptoms include pain in the lower abdomen and frequent urination.

Diagnosis

From the most noninvasive to the most invasive diagnostic test, these include:

1. Urine microscopy to detect cancer cells in the urine
2. Cystoscopy A tube inserted into the urethra to look into the inner wall of the bladder is highly diagnostic
3. Ultrasound, CT Scan, and biopsy can also be further used to identify severity of the tumor.

Treatment

Once the tumor is diagnosed, treatment would depend on the severity of the tumor. For both invasive and noninvasive tumors, definitive therapy is surgery, known as transurethral resection of the bladder tumor (TURBT). The cancerous bladder tissue is removed through a cystoscope as done for diagnosis. The bladder is then flushed with chemotherapy agent to kill any residual cancer cells in the bladder. This is then followed by BCG vaccine, which is again done 1 to 4 weeks for several months to avoid recurrence. In some cases, radiotherapy may also be included.

Bladder Tumor and Its Common Causes

Many people are embarrassed to talk about their urine colour or urine problem with anybody, including their doctor. But, what people always forget is that strong smelling urine and the change in the colour of the urine is a serious issue. Your urine colour directly tells you about your health, especially your inner body. So, without being embarrassed you should consult a doctor, if and when, you find foul odour in your urine. Following are some of the reasons for the causes of strong smelling urine.

You are dehydrated: Urine is not supposed to leave odour. It should be odourless, but if you find strong smell in your urine, you should consult a doctor immediately. The most common reason of foul odour in your urine is dehydration. If the amount of water needed in your body is not enough then, there will be less water in your body as a result the waste products will not be diluted in water being more concentrated making the urine darker and more odour. But once you start drinking water, it should go normal. Normally, this kind of situations occur in early morning when your water intake is less or not at all. But drinking lot of water will solve this issue immediately.
More alcohol or caffeine intake: If you are habituated to drink a lot of coffee then it may happen that you find strong smell of coffee in your urine. Although it is not very problematic yet it is healthy if you reduce the intake of coffee in your daily life in order to have a healthy digestive system. Not just coffee but even alcohol could be the reason of irregular or need to urinate a lot more than usual.
Bacterial Infection: There could be bacterial infection or kidney infection which could lead to strong smell of urine. In order to ensure you should go to a doctor and get important tests done. Then the doctor can suggest treatment according to your results and if all the results are normal then you could be suggested to maintain a balanced diet on regular basis.
Imbalanced Diet: The problem can sometimes come from the use of certain vitamins from imbalances in your diet. There are substances like nitrates and phosphates in the urine which can give dark colour and odour. You should always have a proper diet and follow it in order to have a healthy digestive system. Eating lot of garlic and onion can also bring odour in your urine.
Diabetes: If you are diabetic, it may be possible that you find dark urine and odour in your urine. It indicates that your sugar level is not normal and gone much high than normal. If you are not diabetic then it may be a sign of diabetes so you should get diagnosed immediately with your doctor.
There are multiple causes of strong smelling urine but most of them could be cured easily if diagnosed immediately. But in order to avoid this issue it is better to be careful with your diet and drink a lot of water. At least three litres of water a day is an absolute necessity!

Strong Smelling Urine - 5 Common Reasons Behind it!

Hunner's ulcers, simply put are painful ulcers in your urinary bladder. These ulcers are inextricably linked to another disorder called the painful bladder syndrome or intestinal cystitis. They occur in 10 to 15 percent of people with interstitia cystitis. These, in fact, are red patches or lesions on the bladder wall which can stiffen tissue and cause reduced bladder capacity. Hunner s ulcers bleed, ooze pus and can be of different sizes. The ulcers in the bladder can be extremely painful and uncomfortable.

These are called Hunner s ulcers because they were first described by Dr. Guy LeRoy Hunner, a Johns Hopkins gynecologist, in 1915. Since Hunner s ulcers are seen only in people with intestinal cystitis, it s important to know more about this painful life-altering bladder disorder before we can even understand how to deal with them.

Interstitial cystitis (IC)
IC is also called painful bladder syndrome. Another important thing to know about IC is that it strikes more women than men. IC is a chronic disorder and there s no cure for it. It causes recurring bouts of pain and pressure in the urinary bladder and the pelvic area. This is often accompanied by an urgent and frequent need to urinate. Sufferers may have to rush to the  loo  as much as 40, 50, or 60 times a day.

Diagnosis
Hunner's ulcers can only be accurately diagnosed by doing a cytoscopy which involves inserting a fibre-optic tube through the urethra to look at the bladder wall closely. During this procedure, a tissue sample from the bladder wall is usually also taken to rule out bladder cancer. Cytoscopy is usually done with hydrodistention under local anesthesia. This involves filling the bladder with a liquid for stretching it to provide a closer view of the bladder wall. Usually, a urologist performs this surgery along with a gynaecologist. IC and also Hunner s ulcers are both a diagnosis of exclusion. This means that they re diagnosed only after a number of other conditions have been ruled out.

Hence, the urologist will first take your thorough medical history, followed by a physical exam and a pelvic exam for women patients and perform tests for ruling out infection, and other disorders like bladder stones and cancer, kidney disease, multiple sclerosis, endometriosis, sexually transmitted diseases amongst others. Only after these tests are inconclusive or uncertain and if there is blood in urine, will the urologist go for cystoscopy.

Treatment
There's no cure for IC, but Hunner s ulcers can be cured by burning them off the bladder wall. Called fulguration, the process uses electricity or laser to burn the ulcers on the bladder wall. Resection is also used in which skin from around the Hunner s ulcer is cut for removing both the ulcer and the inflamed tissue around it. The problem is that ulcers may recur in the same location.
So, managing IC becomes critical. Your doctor can try to treat the patient with one treatment or with a combination of treatment depending on the condition of the patient.

Pain medicines are the first line of treatment to manage Hunner s ulcers and IC both, and many patients do go in for this. Patients also find relief by modifying their diet to remove foods and drinks like caffeinated beverages- tea, coffee, colas etc. Sodas, artificial sugars and fruit juices, especially Cranberry juice can trigger intense pain and discomfort, so these are usually contraindicated. Another important aspect is patient education about normal bladder function and tips on self-care and behavioural modifications like stress control to manage Hunner s ulcers.

Hunner's Ulcer In Urinary Bladder - How They Can Be Treated?

Cystitis is a condition which is characterized by bladder inflammation that is usually a result of bladder infection. This disorder is very common among women. The condition tends to get better in a few days without any treatment. In case of chronic cystitis, long term treatment may be required.

Symptoms
Common symptoms include excessive urination (may be dark in color) and a burning pain during urination. One might feel generally unwell, tired and may experience cramps in the lower abdomen. In case of children, there may be a rise in the body temperature, coupled with weakness and vomiting.

Causes

Engaging in sex (irrespective of whether one is using protection or not) can result in this condition.
Inserting objects such as tampons into the urethra to release the bladder can most definitely result in this condition.
Using contraceptive measures such as diaphragm.
It occurs when bacteria which is present in the bowel or on the skin comes in contact with the bladder via the urethra. Women are at an increased risk as their urethra is shorter and the anus is close to the urethra.
Homeopathy and Cystitis
Homeopathy is a system of treatment that is natural and holistic. It does not have any side effect like the other conventional treatments. The various homeopathic remedies for cystitis are  

Cantharis: Cantharis is a homeopathic remedy that is very effective in treating infections. In case of bladder inflammation and pain while urinating, this remedy is preferred. For cystitis with an inflamed bladder as the root cause, this remedy is very effective.
Apis Mellifica: In case of chronic bladder infection, Apis Mellifica is administered. It cures the inflammation and also gets rid of the swelling. This also helps in relieving any burning symptom that you may experience while passing urine.
Staphysgaria: Staphysgaria is a homeopathic remedy which is used to treat symptoms of cystitis that include a sharp pain in the urethra accompanied by involuntary discharge of urine. There may also be a constant urge to urinate.

Bladder Inflammation - Effective Homeopathic Treatment for it!

Stone diseases are a part of health issues related to the urological system in our body. Depending on their position, they may be classified into kidney stones and ureteral stones. Stone diseases are extremely common in nature and if treated timely it does not cause much damage to the body.

Types of Stones in the Human Body:

There are four types of kidney stones and ureteral stones in the human body namely   calcium, uric acid, struvite and cystine. The main difference between kidney stones and ureteral stones is that of the location. Kidney stones are transformed into ureteral stones when they pass from the kidney into the ureter.

Warning Signs to detect Kidney and Ureteral Stones

Kidney stones may be present in your body but they do not cause any obstructions unless they move into the ureter. Symptoms to detect the presence of stones in your body include  

  Intense and shifting pain in the lower abdomen and groin
  Frequent and painful urination
  Presence of blood in urine
  Nausea and vomiting
  Frequent fever accompanied by chills

Modes of Diagnosis:

The following methods are used to diagnose kidney stones/ureteral stones in the body-

  Imaging Tests   X-rays and CT scans are used to detect the presence of bigger and smaller stones respectively.
  Urine Tests   They help to detect the presence of stone forming particles in urine thus helping to diagnose stones in the kidney.
  Blood Tests   They help display levels of calcium and uric acid in the blood and monitor the general health of kidneys.

Treatment of kidney/ureteral stones:

Treatment of stones depends on their size and severity. For smaller stones, doctors recommend drinking 2-3 litres of water per day that help in flushing out the stone through urine. Doctors also prescribe medicines which helps break down the stone and reduce pain.

If the stones are large in size and exhibit severe complications, then the urologist will resort to the following treatment procedures-

  Shock Wave Lithotripsy (SWL)   In this process, a machine called lithotripter is used which passes ultrasonic waves through the skin to break up the stone into smaller components. The shattered pieces then pass out of the body through the urinary tract.

  Percutaneous Nephrolithotomy (PNL)   This is an endoscopic method used to remove large stones, which are not possible to eliminate through SWL. This is an invasive procedure and general anaesthesia is done prior to surgery.

  Ureteroscopy   In this process, a ureteroscope is inserted into the urethra to locate the stone and a tool is used to break it into smaller pieces or is taken out as a whole.

Prevention of Kidney and Ureteral Stones

Certain lifestyle changes can go a long way in preventing stones in the body. Some of them include drinking lots of healthy fluids, reducing consumption of oxalate-rich foods and animal protein, reducing sodium intake and controlling one s body weight.

Maintaining a healthy lifestyle and taking prompt medical action in case of detection of stone lessens the harmful effect of kidney and ureteral stones in the body.

Stone Disease - All You Should Know About It!

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