Causes and symptoms of acute tubular necrosis

Damage or destruction to tube-like structures known as tubules in the kidneys can bring about the development of acute tubular necrosis (ATN) and subsequently, acute kidney failure.

What causes acute tubular necrosis (ATN)?

A lack of supply of oxygen to the cells in the kidney is the most common cause of this condition. The reason as to why oxygen may not reach the cells and tissues of this organ could be restriction or blockage of the pathways. When this happens, the kidneys get damaged. Dehydration is the most important cause of ATN which may be because of loose motions, vomitings, heat stroke etc.

Health conditions such as diabetes, heart attack, and stroke can bring about a decrease in blood flow to the organs resulting in ATN and death of cells. Similarly, the presence of toxic substances in the blood can also lead to tubules damage and change the way the cells function in the tubules.

Other causes that may lead you to develop ATN may be medications, radiology dyes, anesthetics and chemicals that cause your body to react adversely.

In addition to these causes, a number of factors can put you at risk of ATN and there are:

- An injury to the body, more specifically your kidneys can cause clotting of the blood vessels
- An adverse response to blood transfusion
- Instances of septic shock can slow down blood flow to the organs
- A major surgery that can interrupt blood supply to the organs

What are the symptoms of the condition?

The symptoms associated with the condition can vary depending on the severity of the problem.

You may experience:

- Troubles in waking up
- Drowsy feeling even during daytime
- Feelings of lethargy
- Feelings of excessive thirstiness
- Problems with urination
- Fluid retention problems
- Instances of confusion
- Feelings of nausea



Can Acute Tubular Necrosis Cause Kidney Failure?

Blood in urine, medically known as Hematuria is not usually a cause of concern, but it can translate into an adverse condition if left unevaluated. The kidneys and other structures in the urinary tracts such as urethra (tube connecting the bladder to the outer part of the body); bladder (that stores the urine) and ureters (tube joining the bladder to the kidney) are the sources of blood flow to the urine. Hematuria can be accompanied by symptoms such as discharge of tea-colored, brownish-red or pink colored urine due to the presence of red blood cells, traces of which can only be detected under the microscope.

Underlying causes behind this disorder might be

Urinary tract infections is where the bacteria enter the body through the urethra and begin to proliferate in the bladder.
Kidney infections (pyelonephritis) is when bacteria infiltrate into the kidneys from the bloodstream or travel up from the uterus to the kidneys.
A kidney or a bladder stone is marked by the minerals in the concentrated urine precipitating out and molding into crystals that deposit on the bladder or kidney walls.
Enlarged prostate is a condition in which the prostate gland, that is situated just below the bladder surrounding the upper part of the urethra, starts growing as males head towards their middle age.
Kidney disease such as glomerulonephritis causes swelling of the kidneys, thus disrupting the filtering system.
Bladder, kidney and prostate cancer are also possible causes.
Hereditary disorders such as sickle cell anemia (a hereditary disease of the red blood cells in the hemoglobin) can also pose as a cause behind this disorder.
Kidney injury as a result of heavy blows, accidents or injuries sustained while playing a spot can also contribute to this condition.
Medications such as penicillin or the anti-cancer drug  cyclophosphamide 
Strenuous physical exercises like intense workout or running may also result in Hematuria.
Treatments
There is no fixed cure for Hematuria; instead the doctor would work on treating the repressed conditions behind the symptoms, such as prescribing antibiotics to heal the urinary tract infection or a medicine to shrink and normalize the enlarged prostate or administer a shock wave therapy to destroy the kidney or bladder stones.

Blood in Urine - 10 Causes Behind It

Urinary incontinence or the involuntary urination is a common and distressing problem, which may have a large impact on quality of life. The most common types of urinary incontinence in women are stress urinary incontinence and urge urinary incontinence. Women with both problems have mixed urinary incontinence. Stress urinary incontinence is caused by loss of support of the urethra which is usually a consequence of damage to pelvic support structures as a result of childbirth. It is characterized by leaking of small amounts of urine with activities which increase abdominal pressure such as coughing, sneezing and lifting. 

Additionally, frequent exercise in high-impact activities can cause athletic incontinence to develop. Urge urinary incontinence is caused by uninhibited contractions of the detrusor muscle. It is characterized by leaking of large amounts of urine in association with insufficient warning to get to the bathroom in time.

How to diagnose urinary incontinence?

Stress test: The patient relaxes, then coughs vigorously as the doctor watches for loss of urine.
Urinalysis: Urine is tested for evidence of infection, urinary stones, or other contributing causes.
Blood tests: Blood is taken, sent to a laboratory, and examined for substances related to causes of incontinence.
Ultrasound: Sound waves are used to visualize the kidneys, ureters, bladder, and urethra.
Cystoscopy: A thin tube with a tiny camera is inserted in the urethra and used to see the inside of the urethra and bladder.
Urodynamic: Various techniques measure pressure in the bladder and the flow of urine.
Ayurvedic Management of Urinary Incontinence: 
Ayurveda is a very effective natural treatment for Involuntary Urination. Medicines help to treat the root cause of disease. Ayurveda remedies are known to be perfectly safe and have been tried by thousands of patients all over the world bedwetting are perfectly safe. These natural remedies do not have any side effects at all

Urinary Incontinence and How It Can Be Treated with Natural Remedies?

Chronic kidney disease or CKD is the decreased function of the function of the kidney for a minimum of three months or more. In this the end stage renal disease usually refers to the end of the kidney function where the kidneys work for less than 15% of what they are supposed to. The kidneys play a vital role in the human body and if they do not function properly then a person can die. The functioning of many organs depends on the kidneys. However, the main function of the kidneys is to remove the products and regulate blood and water, control blood pressure, promote healthy and strong bones, and produce hormones.

Here are 5 facts about kidney disease you should know about:

1. Causes of the kidney disease: There are two main common causes of the end-stage kidney disease. These are preventable causes. These are diabetes and high blood pressure, but then kidney disease can be caused by other inherited diseases such as infection, trauma or polycystic kidney disease.

2. Serious Stages: The kidney disease has five stages and stage 5 is known as the end stage renal disease; this is the point where patients usually need dialysis or kidney transplant to lead a sane life. The stages of kidney disease are:

Stage 1   Slight kidney disease
Stage 2   Mild decrease in kidney function
Stage 3   Moderate decrease in kidney function
Stage 4   Severe decrease in kidney function
Stage 5   End stage renal disease

3. Detection of the disease: Kidney disease is usually difficult to detect because of the presence of very few symptoms. Age, gender along with the blood test is one way to determine information regarding kidney function. The people who are at a risk of getting kidney disease are:

    Over the age of 55 years
    People who suffer from hypertension and diabetes
    Ethnic groups such as Asians, Africans, Americans, Pacific Islanders and Hispanics

4. Signs and Symptoms: CKD is usually considered to be a silent disease and many people don t know that they are suffering from the disease. The signs and symptoms of the disease are:

    Fatigue and weakness
    Nausea, vomiting and loss of appetite
    Dizziness
    Numbness and headaches in hand and feet
    Frequent urination

5. Renal Replacement Treatment: This is the treatment for the end stage of the kidney disease. Dialysis involves the replacement of some part of the lost function of the kidneys and is usually continued throughout life. There are 2 types of dialysis:

    Hemodialysis: This cleans the blood via an artificial kidney which is hooked to the machine
    Peritoneal Dialysis: This removes the excess water and waste products and cleans the blood of the body by using the peritoneal cavity as a filter. 

5 Facts About Kidney Disease You Should Know

Many people are embarrassed to talk about their urine colour or urine problem with anybody, including their doctor. But, what people always forget is that strong smelling urine and the change in the colour of the urine is a serious issue. Your urine colour directly tells you about your health, especially your inner body. So, without being embarrassed you should consult a doctor, if and when, you find foul odour in your urine. Following are some of the reasons for the causes of strong smelling urine.

You are dehydrated: Urine is not supposed to leave odour. It should be odourless, but if you find strong smell in your urine, you should consult a doctor immediately. The most common reason of foul odour in your urine is dehydration. If the amount of water needed in your body is not enough then, there will be less water in your body as a result the waste products will not be diluted in water being more concentrated making the urine darker and more odour. But once you start drinking water, it should go normal. Normally, this kind of situations occur in early morning when your water intake is less or not at all. But drinking lot of water will solve this issue immediately.
More alcohol or caffeine intake: If you are habituated to drink a lot of coffee then it may happen that you find strong smell of coffee in your urine. Although it is not very problematic yet it is healthy if you reduce the intake of coffee in your daily life in order to have a healthy digestive system. Not just coffee but even alcohol could be the reason of irregular or need to urinate a lot more than usual.
Bacterial Infection: There could be bacterial infection or kidney infection which could lead to strong smell of urine. In order to ensure you should go to a doctor and get important tests done. Then the doctor can suggest treatment according to your results and if all the results are normal then you could be suggested to maintain a balanced diet on regular basis.
Imbalanced Diet: The problem can sometimes come from the use of certain vitamins from imbalances in your diet. There are substances like nitrates and phosphates in the urine which can give dark colour and odour. You should always have a proper diet and follow it in order to have a healthy digestive system. Eating lot of garlic and onion can also bring odour in your urine.
Diabetes: If you are diabetic, it may be possible that you find dark urine and odour in your urine. It indicates that your sugar level is not normal and gone much high than normal. If you are not diabetic then it may be a sign of diabetes so you should get diagnosed immediately with your doctor.
There are multiple causes of strong smelling urine but most of them could be cured easily if diagnosed immediately. But in order to avoid this issue it is better to be careful with your diet and drink a lot of water. At least three litres of water a day is an absolute necessity!

Strong Smelling Urine - 5 Common Reasons Behind it!

A problem pertaining to the storage function of the bladder that results in bouts of sudden, often uncontrollable urge to urinate is referred to as an overactive bladder. This condition which is marked by unconditioned or involuntary loss of urine can sometimes be quite difficult to stop. People who experience such a condition often feel humiliated and as such tend to limit their social and work life. Despite such, only a few are conscious that a brief evaluation can help them manage and overcome an overactive bladder.

Mechanism of urination

During urination, the urine proceeds from the bladder and flows into the urethra which is located at the tip of the penis in men and above the vagina in women. As the bladder fills, the nerve signals in the brain prompts urination by coordinating the relaxation and contraction of the urinary sphincter muscles.

Causes and symptoms of an overactive bladder

Primarily caused due to involuntary contraction and relaxation of sphincter muscles, several conditions can lead to overactive bladder. 

Some of them are: 
1. Parkinson's disease, alzheimer's and other neurological disorders
2. Poor kidney function due to diabetes
3. Medications that lead to increased production of urine
4. Bladder abnormalities like tumors or stones
5. Constipation
6. Excessive consumption of caffeine or alcohol

Some of the common signs of an overactive bladder are:
1. Bouts of sudden, uncontrollable urge to urinate
2. Awakening at night frequently to urinate
3. Urinating more than eight times a day

Risks
The risk of an overactive bladder gradually increases with age. Conditions, such as diabetes and an enlarged prostate results in the increased likelihood of an overactive bladder. People who have previously faced strokes and heart attacks experience cognitive decline, which often times lead to the development of an overactive bladder.

Urinary incontinence as well as a host of associated factors can be detrimental to your life. Emotional distress, interrupted sleep cycles and depression are some of the observed complications of this condition.

Thus if you experience or entertain suspicion of an overactive bladder, you should consider visiting a general physician who might refer you to a specialist, if need be.

All about Overactive Bladder

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