Schnitzler s syndrome is a very rare condition described by a reddish rash that looks like hives (urticaria) and lifted levels of a particular protein in the blood (monoclonal IgM gammopathy). Symptoms connected with the Schnitzler disorder may include increased levels of fever, joint inflammation, joint pain (arthralgia), bone agony, and different discoveries, for example, swollen lymph nodes (lymphadenopathy). It also causes weight reduction, discomfort, exhaustion, and broadened spleen and liver. This condition should be treated in terms of taking care of the symptoms so that they do not become debilitating.

Some of the other symptoms include the following:

Urticaria (hives) depicts red raised patches of the skin. These are once in a while irritated. They may last for about 12 hours to 3 days. This may become severely painful if not treated in time.
80% of such patients suffer from painful or swollen. A few patients experience bone pain as well.
High fever might be there accompanied by chills and night sweating. This can give rise to further uneasiness and is usually caused when the immune system is attacked by the ailment.
One of the main symptoms of the Schnitzler disorder is monoclonal gammopathy. This mostly means a raised level of immunoglobulin M (IgM)
Reasons behind it

The main cause behind the Schnitzler syndrome is unknown. Specialists believe that particular parts of the immune system may not work appropriately in the end because of the Schnitzler syndrome. Individuals with the Schnitzler disorder additionally have monoclonal IgM gammopathy, in which abnormal production of immunoglobins result in elevated levels of immunoglobulin M (IgM) in the body. Immunoglobulins are proteins delivered by the white blood cells. A few analysts believe that IgM antibodies accumulate in the skin (epidermis), setting off a reaction that causes the rash. At the time of diagnosis, IgM levels may just be somewhat raised and may stay stable for quite a long time.

Diagnosis

The diagnosis of the Schnitzler disorder is based upon an intensive clinical assessment, patient history, rejection of different other disorders and proof of fever, joint pain or aggravation, bone pain, discernible lymph nodes, amplification of the liver or spleen, lifted quantities of white platelets (leukocytosis), raised red platelet (erythrocyte) or anomalies, which can uncover expanded bone thickness (osteosclerosis).

Treatment: 
Anakinra is a successful treatment for Schnitzler syndrome. It is also very commonly used to treat rheumatoid joint inflammation. The following medicines and therapies have been proven to be successful for treating the Schnitzler disorder over a period of time. These are as follows:

Antihistamines
Nonsteroidal calming specialists
Systemic steroids (prednisone)
Hydroxychloroquine
Colchicine
Dapsone
Pamidronate
Thalidomide
Pefloxacin
Phototherapy
Immunosuppressive specialists (ciclosporin, methotrexate, cycloposphamide)
Biologic specialists (tocilizumab, rituximab)
The Schnitzler disorder is a long-term infection, so stopping a promising treatment can tend to cause a relapse and may cause the disease to reappear. Also, the medicines mentioned above should not be taken without consulting a doctor as they can have sever side effects, if not administered under the guidance of a physician.

Schnitzler Syndrome - Things You Must Know About It!

Hives is a very common condition and about 20% of the world has got it at some point in their lives. There are many causes to it ranging from blood transfusions to certain allergic reactions to food. It starts off as an itchy patch of skin but slowly swells and turns into red welts. There are certain factors which makes the itching worse including stress, alcohol and scratching the area of skin which was itchy in the first place. 

Causes
Here are all the causes and symptoms of hives:
1. Food
Allergic reactions to foods such as nuts, eggs and shellfish are a common cause of hives.

2. Medications
Certain medications also have a side effect of causing hives. Penicillin and sulfa are two of the antibiotics, which can cause hives. Ibuprofen and Aspirin are also two other medications, which are commonly known to cause hives.

3. Infections
Both bacterial and viral infections can lead to hives. Strep throat, urinary tract infections, common cold and hepatitis are some of many bacterial and viral infections, which may cause hives.

4. Stimuli
Certain factors such as temperature, pressure, sun exposure and other physical stimuli may cause hives as well.

5. Plants and animals
Dander in animals are the flakes of skin in their fur. Moreover, coming into contact with certain poisonous plants may cause hives.

6. Insects
When insects sting or bite you, you may get hives.

7. Latex
Latex is a type of rubber used in many types of clothing. It has been said that wearing clothing made out of latex can cause hives.

8. Pollen
Pollen is a light powdery substance produced by plants such as oak trees. It travels through the air and may cause hives if it comes into contact with your skin.

Symptoms
1. Bumps
Itchy red bumps appear on the skin when you have hives. Sometimes, the bumps can be skin-colored as well.
2. Blanching
When the bumps turn white after you press them, it is known as blanching. Blanching is the only clear symptom of hives.

Hives: Causes and Symptoms

One of the most important functions of the skin is protection. During this process, it comes in contact with various substances including chemicals, pollen, dust, and other pollutants. While it does protect the overall body from all these, there is some damage that is inevitably done to the skin through these exposures. Different skin and different bodies react differently to these, and while some may have no reaction, others develop allergies. This is also defined by how strong the person s immunity is.

Hives is one of the most common skin allergy responses. While it is not easy to pinpoint what causes the allergy or the hives, the causative agent can be nailed by observing patterns and excluding out some of the causative agents. There are a set of regular household and surrounding items that could lead to urticaria, and working around these can help pin down the source.

Origin: When the body encounters a foreign body, it produces what are known as histamines. When they are produced, the plasma in the cell leaks out, producing a red and swollen appearance. Hives are red, itchy, raised patches on the skin. They are seen in about 20% of the population. Hives are usually allergic in nature, implying that they occur when there is a foreign substance that induces an allergic reaction. Hives can appear either due to coming in touch with some substance or due to eating some allergy-inducing substance.

Hives can be acute or chronic. Acute is when the hives appear in response to an allergic reaction. These usually disappear in a matter of days to a week at the maximum. In some people, they could be chronic and can last for months together.

Treatment: Given that they are allergic in nature, managing hives includes a combination of immediate treatment as well as preventive measures. While most are topically managed, others might require systemic intervention also.

Once the hives have developed, the following can help in the relief of symptoms and prevent from spreading further. The redness and swelling will take some time to disappear.

Avoid tight-fitting clothes
Use cool compresses on the hives
Avoid warm or hot shower
Stay in a cooler room
Avoid itching the hives
Use topical moisturizer to prevent dryness
Use topical steroid cream to manage the inflammation
Take a systemic antihistamine or an injection of epinephrine if required.
While these help in managing the hives which have occurred, preventing is via the following.

Avoid the source once identified
If the source is not yet known, record when the hives are occurring
Manage stress and see hives appear much less
Increase moisturizer use
Keep an antihistamine handy so you can take it immediately in case of suspected hives. 

Urticaria (Hives) - The Best Way It Can Be Treated!

Urticaria or hives are red, raised lesions that occur anywhere on the body, usually around the trunk, hands and legs. They appear as small round rings or large patches that changes shape, may itch and be surrounded by a red flare. They can be acute or chronic, with acute almost always being an allergic reaction. It is often due to unknown causes, ranging from chronic irritation to parasitic infection to temperatures to water types.

Homeopathy treats diseases as a whole, and similarly, when treating urticaria tries to identify associated symptoms and thereby treat the cause also. After a detailed discussion about predisposition and associated symptoms, a customized remedy will be prescribed, which may include one of the following common homeopathic remedies.

Apis Mell: The hives consist of isolated patches that are painful, tender, itch at night, feel like bee stings, become purple. There is burning pain, slight fever, and warmth of the surrounding skin. It is worsened by changing weather and exercise, causing severe itching and burning. The patient may already have asthma.
Arsenic Album: The urticaria is caused by eating shellfish and causes burning and restlessness. The condition gets worse being at the seaside and by getting into sea water. Arsenic is also useful to treat urticarial symptoms during the recession of the lesions. The person also could be down emotionally with depression, despair, indifference and irritability. If the lesions are more severe, the restlessness is also severe. It is worse after midnight, from 1 to 2 a.m.
Rhus toxicodendron: Prepared from the leaves and bark of the plant poison ivy, Rhus works on multiple body systems including skin, joints, eyes, extremities, and overall vitality. In addition to urticaria, it is also used in cellulitis, arthritis, fevers, etc. It is effective if the urticaria has a burning sensation, inflamed reddened rash that is worsened by cold and improved by warmth.
Urtica urens: Made from a plant called stinging nettle, which itself has a tendency to produce urticaria, it is used when there is urticaria from bee stings or after eating shellfish. The lesions are red with severe burning and itching, recurring every year, could be associated with weather changes.
Natrum Muriaticum: The common salt sodium chloride is potentized, and its inner healing power activated. It is used for chronic urticaria, where the lesions develop after severe irritation.
Dulcamara: The lesions develop followed a general prickly sensation setting in and at night when it is cold and damp. The hives are irregular white patches surrounded by a red area that itch badly. The hives are associated with violent cough, swelling of the lymph nodes, fever, restlessness, sleeplessness, decreased appetite, nausea, vomiting, bitter taste, and intense aching in pit of stomach.

Urticaria - 6 Homeopathic Remedies For Hives Disease

 Hives , also known as urticaria, is the outbreak of pale red, swollen bumps on the body. It can occur on any part of the body including the face, back, arms or legs. It is a type of hypersensitivity reaction in which the cause for the reaction is idiopathic (unknown). Also, it can come in various shapes and sizes. Hives can be associated with redness, itching, and a burning and stinging sensation. These can last for more than a minute or even more than that; up to days.

What causes hives?
Most of the times, hives are idiopathic, i.e. the reason that causes this type of hypersensitivity reaction is unknown. The bumps are caused by the action of histamine that makes the plasma in the blood leak out of the small blood vessels. Histamine is a substance that is released from a specialized cell and is what causes allergic responses in general. There are three types of hives- namely, acute, chronic urticaria and physical urticaria. Acute urticaria is when the hives last for less than six weeks. Chronic urticaria occurs when the hives last for more than six weeks. 

Physical urticaria refers to the condition when the hives are triggered due to causes such as heat, cold, sun exposure, sweating, pressure and exercise. Although, this condition is mainly idiopathic, there are common causes that may trigger this condition such as:

Foods such as nuts, fish, chocolates, milk and milk products
Environmental triggers such as pollen grains, dust etc
Medications such as ibuprofen or paracetamol
Insect bites
Latex
Blood transfusion
Bacterial infections including strep throat and urinary tract infection
Pet dander
Plants such as poison oak or poison ivy
What are the symptoms of urticaria?
Hives are usually self-diagnosable. The various symptoms of urticaria are:

Swollen red bumps known as weals
The red bumps can occur suddenly and subside all of a sudden as well
 Blanching which is characterized by the whitening of the swollen red part.
They occur on any part of the body and can change shapes, and sizes. It can become larger or it can reduce in size; it can also move around in the body.

Hives - Most Common 9 Reasons Behind It!

If stressed, consuming certain food and medications can trigger skin rashes. This kind of rash is called hives. It is also known as urticaria. Anyone can be affected by hives, at least 20% of people are affected by hives at some time or the other in their lives. The itching could be severe or mild. It starts as a patch of scaly white skin that develops into red welts over time. To make sure the itching does not worsen, scratching, emotional stress, alcoholic drinks and exercise should be avoided.

Symptoms
1. Itchy bumps that are raised and are either red or flesh coloured
2. If the hive is pressed in the middle, the skin whitens this symptom is called blanching.
3. The hive formation can appear anywhere, disappear and then reappear somewhere else.

Common Triggers
1. Certain food like shellfish, eggs, peanuts and other nuts
2. Certain medicines like antibiotics, ibuprofen and aspirin
3. Insect bites or stings
4. Physical causes like pressure, sun exposure, cold, exercise and heat
5. Latex
6. Blood transfusions
7. Bacterial infections
8. Pet allergens
9. Viral infections like the common cold, hepatitis and infectious mononucleosis
10. Certain plants like poison ivy and poison oak
11. Pollen

Treatment
There is no distinct cure for hives. But you can control its symptoms in the following ways:
1. Antihistamines help in blocking histamines, which cause the allergy symptoms. Non sedating or low sedating Antihistamines will be mostly recommended by your doctor.
2. If episodes of hives are several, it may require limited treatment with prednisone. Prednisone will be able to lessen the symptoms.
3. If the symptoms get severe enough so much so that it swells up your tongue and you have problem breathing, then the doctor might prescribe an epinephrine. However, these symptoms can mean another thing, an anaphylaxis shock. Epinephrine is the only treatment for an anaphylaxis shock.

Prevention
If what caused hives to break out is figured out, then measures should be taken to avoid or eliminate the triggers.
1. Avoid eating food items that triggered the symptoms in the first place
2. If harsh soaps, frequent bathing cause hives, they should be avoided
3. Tight clothing should be avoided
4. If cold triggers hives, then wear warm clothing, wrap a scarf and do not swim in cold water.
5. Avoid sun exposure and wear sunblock
6. If a specific medication is causing the hives, inform your doctor.

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