The liver can be transplanted either from the living-donor or from the deceased donor. Liver transplant surgery includes the transplantation of a part of the liver from the donor to the donee who has a damaged liver and does not function well. Living-donor liver transplant is more common especially among children as the number of liver donee are more than the available deceased donors of the liver.

Living liver donors are the alternative for the donee waiting for a liver transplant from a deceased person. The remaining liver of the living donor, after the transplant, regenerates itself and reoccurs to its usual capacity and volume within a few months post the surgery. The donated part of the liver to the donee also regenerates and restores to its normal functioning.

Most often, the living-donor of the liver is a close relative or friend. Everyone or anyone cannot donate a liver but only those can who have the matching liver depending on age, organ size, blood type, and other health and medical factors. Both the donor and the donee have to go through a thorough medical examination before the transplant to know the potential outcome and risk involved.

Procedure-
For the transplant, the donor is first operated and the required part of his/her liver is removed. The donee s damaged liver part is then replaced by the healthy liver part of the donor. Both the donor s and the donee s operated liver is then attached with the bile duct and the blood vessels. Both the patients are kept under observation for some days for the medical team to know if they are having any health issue due to the transplant. The operated liver regenerates itself within certain months and starts functioning normally.

Precautions for the Donor-
Although the donor can go back to normal life routine a few months after the transplant there are a number of precautions that should be taken into account to avoid any health issue or liver damage.
  Avoid smoking.
  Avoid consumption of alcohol.
  Eat on time or do not starve or overeat.
  Avoid having heavy meals.
  Avoid heavy exercise or weight lifting or physical work.

Take Away-
Liver transplant is a surgery conducted to remove the damaged or injured liver of the patient with the healthy liver of the donor. The donor of the liver can either be deceased or living depending upon the availability of the donor and the severity of the donee.

Various lab tests and examinations are conducted on the donor and the donee to confirm their match and assess potential complications before the transplant. The donor is usually someone close to the patient or the donee whose liver has been matched depending upon various factors. As the liver regenerates within a few months, the donor can lead a normal life after the transplant.

Know How To Choose A Liver Donor For Liver Transplant! 

Having some fat in your liver is legit. But, if you have too much of fat say more than 5%-10% of the organ's weight then you are at risk of getting fatty liver disease. At the onset, you can do one important thing to help your liver stop drinking. It causes fatty liver disease.

There are two main types of fatty liver disease

Alcoholic liver disease or ALD
Non-alcoholic fatty liver disease or NAFLD
If you are a woman who is pregnant, you can also get fatty liver disease.
Alcoholic Liver Disease (ALD)

You can get ALD from drinking lots of alcohol. ALD can also present itself after a short period of heavy drinking.
Genetics has a role to play in ALD. Genes can make you hit the bottle and increase your chances of becoming an alcoholic.
Genes can also impact the way your body breaks down the alcohol you drink.
Other root causes of ALD are:

Hep C doesn't cause ALD. it is one of the causes of fatty liver. 
Hep B is also a cause of fatty liver. There are certain medications which may be helpful from person to person besides lifestyle management.
Excess iron in your body
Obesity
Non-alcoholic Fatty Liver Disease (NAFLD)
The cause of NAFLD is not clear, but we know that it tends to run in families.
NAFLD is also more common in the middle-aged and the obese or, those who have high cholesterol and diabetes.

Other risk factors are:

Certain medicines
Viral hepatitis
Auto-immune or inherited liver disease
Gaining weight fast
Malnutrition
Acute Fatty Liver during Pregnancy
Fat can build up in your liver when you're pregnant, causing this kind of fatty liver disease.
It s a serious condition as it can be risky for both you and your baby. It can cause liver or kidney failure in you and your child, both.
Causes are unknown. But, hormones may play a role.
Symptoms of fatty liver disease
This disease can sometimes cause no symptoms for long. But, the things to look out for are-

Feeling tired all the time
Loss of appetite or weight
General weakness
Nausea
Confusion and trouble concentrating
Your liver can become larger
Pain in the centre or right upper part of your belly
In ALD, your symptoms get worse after bouts of heavy drinking. Fatty liver disease is diagnosed during routine exams when your doctor notices your enlarged liver. Ultrasound, blood tests to check for certain enzymes and biopsy of the liver are performed to confirm it.

Treatment

There is no specific treatment for the fatty liver disease.
You can manage it by managing your diabetes and giving up drinking. If you have ALD and you don t quit, you get complications like alcoholic hepatitis or cirrhosis.
Even if you have a non-alcoholic fatty liver disease, alcohol cessation helps.
Losing weight if you are overweight also helps to manage this disease and having a good balanced diet with exercise also shows benefits.

Fatty Liver Disease - Signs You Are Suffering From It!

Liver transplant in the only curative option available for patient who develop cirrhosis of liver due to any cause ( Chronic Hepatitis B , Chronic Hepatitis C, Alcoholic Cirrhosis, NASH etc). Once patient has been diagnosed with cirrhosis it can not be reversed with any non-surgical treatment . Over a period of time patient may develop worsening in liver function resulting in complications of cirrhosis (bloody vomitus, black stools, jaundice , altered sensorium, renal dysfunction, abdominal swelling etc) labeled as  decompensated cirrhosis . These patients require Liver transplant at the earliest and should be reffered to a liver transplant centre immediately. Ideally all patient diagnosed with cirrhosis should be under the follow-up of a gastroenterologist/Hepatologist. The source of graft liver can be from two sources namely from a deceased brain-dead donor or a Living-related donor and termed respectively as DDLT ( Deceased donor liver transplant) and LDLT ( Living Donor Liver Transplant) . However both DDLT and LDLT have nearly 90% success rate and both the procedures have their own benefits and lacunaes. Also the decision to go for DDLT and LDLT may vary for any particular patient. 

Before the Liver transplant 

All recipient and Living donor go thorough evaluation before the transplant process that includes blood investigations, Imaging studies, Cardiac and pulmonary fitness tests, multidisciplinary consultation before the clearance for liver transplant is achieved. The healthcare provider will explain the entire procedure. The healthcare provider is also supposed to answer all your questions. You would be needed to sign a consent form that allows the doctor to do the surgery. Eating food is not allowed at least 8 hours before the surgery. If you cannot stay relaxed before the surgery, a sedative will be given. 

After the Liver Tranplsant 
The recipient surgery lasts for anywhere between 12-16 hrs and donor surgery for 8-12 hrs. After the surgical procedure is complete, you will be taken to the intensive care unit (ICU)and will be closely watched for several days. 

Immediately After the Surgery 
You will most likely have a tube in your throat. This is so that you can breathe with the help of a machine (a ventilator) until you can breathe on your own. The ventilator tube will be removed on next morning when all parameters are found to be satisfactory. All parameters are monitored by round the clock critical care doctors and staff for a few days. The recipient has to stay in the hospital for three weeks and the donor is discharged in one week. 

Blood samples will be collected on a regular basis to check the functioning of the new liver. Antibiotics will be infused via IV channels to prevent you from infections. The area where the operation was done should always be kept clean after you have reached home. Any stitches or surgical sutures will be removed at a follow-up visit.

Complications that may arise 
Blocked blood vessels to the new liver, bleeding, an infection, leakage of bile or blocked bile ducts, or the new liver not working for a short time right after surgery are a few complications that may arise. Not to aggravate the condition, in the case of a complication, it is imperative to visit your doctor.

Liver Transplant - What To Expect Before & After The Procedure?

Excess fat cells in the human body can settle under the skin and cause obesity, Additionally, they may even settle in specific organs and liver is one of them. When fat starts accumulating in the liver, a condition known as fatty liver manifests itself.

There are two types of fatty liver disease alcoholic and non-alcoholic. As the name suggests, the former is triggered by excessive alcohol consumption, whereas the latter takes place due to other reasons. While non-alcoholic fatty liver disease interferes with the normal functioning of the liver, alcoholic fatty liver disease has specific symptoms such as jaundice, fever, spider veins, and increase white blood cells (WBCs) count.

In the world of Ayurveda, the liver is a pitta organ, which is absolutely essential for normal digestion and elimination. Therefore, the pitta dosha should always be in balance so that toxins are eliminated by the liver from the body. A liver disease results when the pitta is aggravated, which can be treated with the help of lifestyle and dietary modifications, in addition to Ayurvedic remedies.

The following are some of the Ayurvedic tips and guidelines that can support liver healing and reduce the symptoms of fatty liver:



Avoid fatty and fried foods as these can further aggravate pitta and heating and overstimulating.
Incorporate cool and non-acidic food items such as berries, pears and melons into your diet.
Eat a combination of steamed vegetable and whole grains such as quinoa.
Consume aloe juice in moderate quantities as it is cooling.
Regularly consume a mixture of 2 grams of long pepper powder and 1 teaspoon honey once a day for complete 1 month.
Consume a decoction of giloy (Tinospora cordifolia), 30 ml, mixed with a teaspoon of honey once a day. 7. Drink plenty of water to cool the body down and eliminate toxins.
Consume 10 to 20 ml of bhumi amla juice.
Take 1 to 3 grams of kakuti powder twice a day with water after meals.
In case you have a concern or query you can always consult an expert & get answers to your questions!

Fatty Liver Diseases - 8 Best Ayurvedic Home Remedies to Treat It

The largest internal organ in the body, the liver, is also one of the silent heroes, which performs close to 500 functions. It produces energy, fights infections, gets rid of wastes, and is a metabolic factory.

There are four major types of liver diseases out of which alcoholic liver disease accounts for about 40% of them. Other types include non-alcoholic liver disease, viral hepatitis and autoimmune (chronic) hepatitis.

Risk factors: The severity of drinking habit is directly proportional to the chances of developing alcoholic liver disease. People who consume more amount of alcohol are more likely to develop the disease. However, it is also not necessary that every person who consumes alcohol develops liver disease.

Following are obvious risk factors for developing alcoholic liver disease.

1. Alcohol dependency: While enjoying a drink is not barred, getting the body dependent on alcohol for regular functioning is definitely a no-no. The rate of developing the disease in people dependent on alcohol is as high as 70%.

2. Females: The way alcohol is metabolized in females could have an effect on the higher risk they face in developing alcoholic liver disease.

3. Obesity: Excessive weight puts additional stress on the metabolic effects of the liver and therefore has a higher tendency to develop alcoholic liver disease.

4. Family history: Strong familial history increases the risk of developing alcoholic liver disease.

Symptoms: The difficulty in diagnosing the disease lies in the fact that there are no clear-cut symptoms that can indicate the diagnosis. Initial general symptoms include fatigue, poor appetite, abdominal pain, nausea, weight loss, loss of energy, and red spider nevi (spider-like blood vessels) on the skin.

As the liver function continues to worsen, there are additional symptoms like swelling of the legs due to fluid accumulation, swelling of the abdomen, jaundice (yellow mucous membranes and skin), redness of palms, impotence, breast swelling, easy bruising, cognitive problems and clay-colored stools. This stage will see liver scarring and subsequent cirrhosis. The second set of symptoms is more diagnostic. An experienced practitioner will be able to suspect and diagnose the alcoholic disease with a detailed history and some liver function tests.

Treatment: If identified early and alcohol habits are reversed, the damages of the liver can be completely reversed. In addition, the following lifestyle changes are suggested:

1. Low-salt diet

2. Hepatitis vaccines (A and B)

3. Medications to manage fluid retention, spontaneous bleeding and infections as the case may be

4. Excessive fluid accumulation in the abdomen may require removal

5. Shunt in the liver to repair blood flow

6. If cirrhosis stage is reached, a liver transplant may be required

While there are many ways to manage alcoholic liver disease, prevention is the best way. Limiting alcohol consumption can definitely help in the prevention of the disease.

All About Alcoholic Liver Disease

Liver is one of the most important organs of the living beings, which performs various functions to keep the body healthy and fit. In some people, the liver will be malfunctioning due to several reasons. So, in these technology days, it is possible for the transplanting it from a healthy person to the patient. Though it is possible but, this transplantation will not be successful for all which can be due to individual health conditions and the stage of liver failure. In order to determine whether a patient can go for the liver transplant or not there are several tests to consider.

Steps to undergo liver transplantation
Liver transplantation is not as simple as it is said, but there are several steps to consider before one thinks of this surgery. Some of the primary steps involved in the process of liver transplantation are:

The first step is to visit the doctor and discuss about liver transplantation.
Then as per the suggestion of the doctor visit the referred liver transplant centre.
The patient is provided with the required information regarding liver transplant.
In this course of time patient will meet several members of the transplant team.
Next medical history of the patient is viewed and recommends some tests to determine the requirement of transplantation.
Then the results of the tests say about the patient condition.
After that, a donor is found out who can be either a living donor or deceased one.
Once the donor is found, transplant centre asks the patient to be prepared for the transplantation.
Process of determining liver transplantation
Determining the requirement of liver transplantation is the most important step which is evaluated by the specialists only. These specialists will be from various fields to know whether it is highly essential or not. This evaluation will be based upon the medical history of the patient, in some of the cases interviewing or discussions with the patient and huge number of tests. All these will be conducted by a professional liver transplant team at the liver transplantation centre only. This team includes:

Liver specialists are also known as Heptalogist
Transplant coordinator
Transplant surgeons
Psychiatrist
Financial coordinator
Social worker
Insurance manager
Anesthesiologist
Dietitian
Chemical dependency specialist
Tests to evaluate the need of Liver Transplantation
Patients are required to present all their previous health records which include X-rays, liver biopsy slides along with the medications during the pre-evaluation of liver transplantation. The common tests that are performed to evaluate the necessity of liver transplantation include following:

Computed tomography for generation of liver pictures
Doppler ultrasound for checking blood vessels from and to the liver is in open condition.
Echocardiogram for the evaluation of heart condition.
Pulmonary function to determine the condition of lungs in respiration process.
Blood test to check the type of blood, clotting ability along with the biochemical status of the blood.
In some patients, AIDS along with Hepatitis are also included.
All the above tests along with the exams help in diagnosing if a patient needs liver transplantation depending upon the condition.

How To Evaluate If Liver Transplant Is Required By A Patient?

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