SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

High blood pressure is a condition which occurs when the pressure of the blood flow through the arteries increases, resulting in intense pressure. Hypertension occurs when the systolic pressure (pressure at which the heart pumps blood) and the diastolic pressure (pressure at which the heart relaxes) is more than 140 and 90 respectively.

Symptoms of high blood pressure are: 

1. Shortness of breath

If you have high blood pressure, then you may experience regular shortness of breath.

2. Headaches

You may experience headaches on a regular basis.

3. Weakness of the heart muscles

Hypertension results in a weak heart which may not be able to pump blood properly.

4. Narrowing of blood vessels

Narrowing of blood vessels may lead to other complications such as failure of the kidneys, heart, and brain.

5. Vision problems

It may lead to vision problems as blood vessels in the eye may be affected.

The various causes of blood pressure are: 

1. Tobacco
If you smoke on a regular basis, you put yourself at an increased risk of getting affected by blood pressure.

2. Lifestyle
Not exercising regularly, eating a sodium-rich diet are all factors which can increase the chances of hypertension.

3. Age
The chances of getting affected by hypertension increase as you age.

4. Weight
Being excessively obese also increases your risk of getting affected by hypertension.

5. Diabetes
Being diabetic makes you more prone to getting affected by diabetes.

6. Hyperthyroidism
If you have an overactive thyroid gland, then it may result in hypertension.

Hypertension may result in various health complications in the body such as:

1. Aneurysm

This is a disorder of the blood vessels which causes the blood vessels to bulge and weaken.

2. Heart attack

High blood pressure causes the arteries to harden and thicken which may lead to a heart attack.

3. Metabolic syndrome

This syndrome refers to a group of complications such as high bad cholesterol levels and insulin levels in the body.

4. Impaired brain functioning
It may also impair your ability to learn and impact your cognitive skills.

Hypertension and High Blood Pressure

A polyp is a cauliflower-like growth on the skin or the mucosal surface. Colon is the medical term for the larger intestine and the rectum. A growth on the mucosal surface of this part of the intestine is known as a colon polyp. Although not visible, colon polyps is present with symptoms, which can lead to their diagnosis. The main cause for concern is that some colon polyps can turn into colorectal cancer, which is the third largest cancer in America.

Types: There are two main types of polyps

Hyperplastic or inflammatory: These are benign growths and do not carry the risk of developing into cancer.
Adenomas: These carry the risk of turning into cancer, and so early detection and intervention is essential.
Though not all polyps develop into tumors, yet all tumors develop from a polyp. There is a strong genetic component, which makes it worse. Someone with inflammatory bowel disease or Crohn s disease is also at a higher risk of mucosal inflammation, which can induce dysplasia and then polyps.

Risk factors:

Family history
Inflammatory bowel disease
Obesity
Diet rich in processed meat and red meat
Smoking
Lack of physical activity
Type 2 diabetes
Being male, being African American
Symptoms: Though often silent, some symptoms which also appear only after the polyp has grown considerably include:

Bleeding with stools   often small amounts intermittently, which is occult bleeding, not visible though
Altered bowel habits (constipation, diarrhea)
Abdominal pain and discomfort
Unexplained weight loss
Anemia (due to blood loss)
Diagnosis: If a person is at risk from medical history and has the above symptoms, then the following are done:

Sigmoidoscopy Viewing the colon and rectum to see if there are any polyps. A biopsy may also be taken to confirm cancerous growth.
Colonoscopy The entire colon is viewed to rule out polyps in other areas of the colon.
CT scan of the abdomen which is non-invasive and can be used as the first step.
Treatment:

If a polyp is diagnosed, then it needs to be removed.
If it turns out cancerous, then detailed evaluation should be done to rule out spread to other areas. Additionally, chemotherapy and radiotherapy may be required to completely eliminate the tumor and contain it.
The surgical removal of the tumor would be planned depending on the stage of the tumor.
Adapting a healthy lifestyle is very essential to managing polyps and preventing cancer. Quitting smoking, managing weight, eating healthy, and being physically active are some ways to prevent colorectal cancer.
Repeat colonoscopy needs to be done to ensure these are not recurrent.

Colon Polyps - What Are The Available Treatment Options?

For long, there have been campaigns and discussions about the harmful effects and diseases associated with alcohol consumption. In most cases, it is not the alcohol, but the quantity consumed that affects a person. Limited consumption of alcohol can, in fact, work to your advantage. Alcohol, when consumed in moderation, helps to avert, check or improve many medical conditions and health ailments.

Deal with common cold effectively: According to research, the antioxidants present in wine helps to fight common cold better. Limited intake of alcohol, red wine to be precise (~1-2 glasses per day), can, thus, help to reduce the instances of common cold significantly.
Weight loss made easy: Studies conducted by the Oregon State University suggest that certain varieties red wine (the Red Muscadine Wine) can play a pivotal role in weight reduction. The Red Muscadine, a variety of wine grapes used to make red wine contains ellagic acid. It is this ellagic acid that helps to cease or slow down the growth and development of the fat cells. Red wine also helps to manage fatty liver effectively.
Keep cardiovascular diseases at bay: The high-density lipoprotein (HDL), also known as the Good Cholesterol is indeed good for the body. It acts as a shield, keeping the heart hale and hearty. Moderate alcohol consumption helps to elevate the level of HDL. One of the main reasons attributing to heart attacks are the small blood clots that block the arteries of the brain, heart, and neck. Alcohol (limited intake) has been able to put a check in the formation of such blood clots.
Reduced instances of cognitive impairment: Reports suggest that people who consume alcohol within limits are less likely to develop dementia and Alzheimer's disease. Moderate consumption tends to make the brain cells fit and more active, thus, enabling the cells to deal with stress and other related factors.
A little wine for a better libido: Limited consumption of wine is good for a better sexual life. Research indicate that the antioxidants present in wine act as a catalyst, resulting in an improved libido (lowers the incidences of erectile dysfunction in men). A little wine can work wonders for women as well (increasing their sexual desires and feelings).
Enjoy a diabetes-free life: Type 2 Diabetes and the associated ailments and complications can make life miserable. However, people who consume a small quantity of alcohol (preferably 1-2 glasses per day) are at a lower risk of developing diabetes (Type 2). A path-breaking finding indeed!
People with moderate alcohol consumption are also at a lower risk of developing gallstones. The high silicone content in beer helps to strengthen the bones, but only when consumed within limits. Beer is also rich in calcium, magnesium, and vitamins (thiamine, riboflavin).

Alcohol In Controlled Quantity - Can It Be Good For You?

It is a common knowledge that beer has health benefits when used in masks, scrubs, as conditioners, etc. This reason is good enough for even non-drinkers to stock up their fridges with cans of beer. 
Here are a few ways by which we can use beer to make our skin and hair better:

Use beer as a conditioner - Beer happens to be an excellent conditioner. Mixing one cup warm beer with a teaspoon of jojoba oil makes a natural, non-greasy conditioner. Wash your hair with your regular shampoo and use this mix as a conditioner. The beer in it will give volume to your hair while jojoba oil will add shine and luster.
Use it for a face pack - Take two to three strawberries mash with a fork, add few drops of beer and make a paste. Rub this paste all over your face in a circular motion. Rinse after 15-20 minutes and apply moisturizer on your face.
Soak in beer laced water - Beer can be used in bubble bath too! Mix some soap with beer of your choice and add the mix to the running bath water. Soak in this water and feel your skin become soft and smooth.
Use beer as a hair-pack - Wash your hair with your usual shampoo. Now pour the mixture made of distilled water, beer, two teaspoon apple cider vinegar and few drops of essential oil (any scent), on your hair. Make sure it reaches the hair that is inside as well. Rinse this mixture with lukewarm water. You can do this once a month.
Get the beer glow - Take half a teaspoon of beer, one egg white and a drop of almond extract. Whisk them together and keep aside. On your washed and dried face, apply the mask and let it dry until your skin feels tight. Wash it off with lukewarm water.
From Lybrate: If you found this tip useful, please thank the doctor by clicking on the heart icon below. Also, spread good health by sharing this tip with your loved ones over Whatsapp, Facebook and other media.

Do You Know What Beer Does To Your Hair & Skin?

The prostate is a vital organ that located between the penis and the bladder. The prostate is involved in the release of the prostate fluid that keeps the sperm properly nourished. Prostate cancer, as the term indicates, is characterized by the abnormal and uncontrolled growth of cancerous cells in the prostate. Though the incidences of prostate cancer are low in India, necessary precautions and diagnostic steps should be carried out to prevent the condition from jeopardizing our lives.

Prostate screening includes two tests known as the Digital Rectal Exam (DRE) and Prostate-Specific Antigen test (PSA). PSA combined with DRE helps to identify prostate cancer at a very early stage. If any of the tests show an abnormality, a doctor might prescribe an ultrasound such as MRI Fusion or Prostate Biopsy to confirm the diagnosis.

Immediate treatment may not be necessary
For low-risk prostate cancer, doctors often recommend active surveillance that includes periodic blood tests, rectal exam, and biopsies.
Active surveillance helps a doctor to continuously track the growth of cancer cells and the possibility of their spread to other areas of the body.
Surveillance is fit for those who are already suffering from a serious condition or for those patients who are above the age of 60.
A surgical procedure to remove prostate cancer
Surgery is considered when the cancer has metastasized to surrounding tissue and the lymph nodes. There are two kinds of surgeries that a patient can go through- a Robot-Assisted surgery and a Retropubic surgery.
Radical Prostatectomy might have risks involved. It is, therefore, wise to discuss the pros and cons of the surgery with the doctor well in advance.
Understanding the treatment options

Radiation therapy: Radiation therapy involves the use of high-powered and high-frequency energy beams to kill cancer cells. Radiation therapy is often used to shrink the size of the cancer cells. There could be two types of radiation therapy-Brachytherapy and External beam radiation. Radiation therapy too can have its side effects. Doctors prescribe several medicines during therapy.
Hormone therapy: Hormone therapy helps to stop the production of a male hormone known as testosterone. This treatment option includes medication that completely stops the production of testosterone, the medications may also block the flow of testosterone on the cancer cells, and surgery to remove the testicles. Hormone therapy is used in advanced cancer stages.
Chemotherapy: Chemotherapy is a drug that goes into the body and kills rapidly growing and metastasizing cancer cells. It is administered through IV (intravenous), or orally as pill or both. This treatment option is employed when cancer spreads to a remote body location and does not respond to hormone therapy.
Biological therapy: Biological therapy involves the usage of the body s immune system to fight cancer. A type of biological therapy known as the sipuleucel-t is used to treat patients with advanced cancer stage and recurring cancer as well.

Prostate Cancer - How Biological Therapy Will Help?

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