Brain metastases from systemic cancer are the most common type of intracranial neoplasm in adults, being almost 10 times more common than primary malignant brain tumors, which cause a significant burden on the management of patients with advanced cancer (1). The lungs represent one of the most frequent sources of metastases to the brain, with a probability of (36 64%) (3). Symptoms suffered by the patients include headaches, epilepsy, focal weakness, numbness or changes in mental status. The prognosis of patients with brain metastases is not optimistic and the median survival time is  1 2 months if left untreated. The 1-year survival rate has been recorded as 10.4% (4,5). The treatment of metastatic brain tumors is complex; not only due to being able to provide local control and improve neurological function, but also due to factors such as age, performance and systemic disease status and the size, volume, location and number of metastases at presentation

CyberKnife is a robotic radiosurgery system with a linear particle accelerator (linac), which is coupled with real-time imaging to track and compensate for the patient s or target s motion. As a relatively non-invasive treatment modality, CyberKnife demonstrates certain benefits, including a more accurate target localization and improved dose delivery for the management of metastatic brain tumors that allows higher biologically effective dose delivery without increased incidence of toxicity.

In the present case, the results for the treatment of multiple brain metastases after CyberKnife surgery with a 7 8 Gy marginal dose was promising. CyberKnife for metastatic brain tumors is an effective and safe method for reducing the marginal dose prescribed for multiple brain metastases and for minimizing the radiation-related neurotoxicities. In conclusion, CyberKnife, a focused, highly-targeted radiosurgery and fractionated radiotherapy is particularly useful for multiple brain metastases. CyberKnife provides the advantage of the management of local recurrence and a tolerable complication rate. Although the treatment of brain metastases has been performed with CyberKnife, the clinical significance and optimal dose fractionation scheme require further investigation.

In case you have a concern or query you can always consult an expert & get answers to your questions!

CyberKnife Therapy Of 24 Multiple Brain Metastases From Lung Cancer!

The prostate is a vital organ that located between the penis and the bladder. The prostate is involved in the release of the prostate fluid that keeps the sperm properly nourished. Prostate cancer, as the term indicates, is characterized by the abnormal and uncontrolled growth of cancerous cells in the prostate. Though the incidences of prostate cancer are low in India, necessary precautions and diagnostic steps should be carried out to prevent the condition from jeopardizing our lives.

Prostate screening includes two tests known as the Digital Rectal Exam (DRE) and Prostate-Specific Antigen test (PSA). PSA combined with DRE helps to identify prostate cancer at a very early stage. If any of the tests show an abnormality, a doctor might prescribe an ultrasound such as MRI Fusion or Prostate Biopsy to confirm the diagnosis.

Immediate treatment may not be necessary
For low-risk prostate cancer, doctors often recommend active surveillance that includes periodic blood tests, rectal exam, and biopsies.
Active surveillance helps a doctor to continuously track the growth of cancer cells and the possibility of their spread to other areas of the body.
Surveillance is fit for those who are already suffering from a serious condition or for those patients who are above the age of 60.
A surgical procedure to remove prostate cancer
Surgery is considered when the cancer has metastasized to surrounding tissue and the lymph nodes. There are two kinds of surgeries that a patient can go through- a Robot-Assisted surgery and a Retropubic surgery.
Radical Prostatectomy might have risks involved. It is, therefore, wise to discuss the pros and cons of the surgery with the doctor well in advance.
Understanding the treatment options

Radiation therapy: Radiation therapy involves the use of high-powered and high-frequency energy beams to kill cancer cells. Radiation therapy is often used to shrink the size of the cancer cells. There could be two types of radiation therapy-Brachytherapy and External beam radiation. Radiation therapy too can have its side effects. Doctors prescribe several medicines during therapy.
Hormone therapy: Hormone therapy helps to stop the production of a male hormone known as testosterone. This treatment option includes medication that completely stops the production of testosterone, the medications may also block the flow of testosterone on the cancer cells, and surgery to remove the testicles. Hormone therapy is used in advanced cancer stages.
Chemotherapy: Chemotherapy is a drug that goes into the body and kills rapidly growing and metastasizing cancer cells. It is administered through IV (intravenous), or orally as pill or both. This treatment option is employed when cancer spreads to a remote body location and does not respond to hormone therapy.
Biological therapy: Biological therapy involves the usage of the body s immune system to fight cancer. A type of biological therapy known as the sipuleucel-t is used to treat patients with advanced cancer stage and recurring cancer as well.

Prostate Cancer - How Biological Therapy Will Help?

Does Viagra add to the risks of melanoma?

Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). This form of skin cancer is mostly caused by exposure to ultraviolet radiations or it may be congenital in nature.

The cancer is easily detected by the naked eye and in 99% cases, the disease can be efficiently treated if detected during its early stages. Women below the 40 year age benchmark have a higher risk of cancer.

Viagra is a health supplement which is consumed in the oral form to minimize all the signs and symptoms of an erectile dysfunction. Viagra is the generic name for Sildenafil, which is used by men.

What does research say?

A medical study has shown that men who frequently use erection-enhancing drugs are 84% more likely to develop melanoma within a period of 10 years. This does not mean that you are bound to get this cancer if you are frequently using an erection enhancing drugs, but it might increase your probability of getting Melanoma.

Risk Factors

Viagra when combined with some other medicine often leads to adverse effects which might lead to cancer as well. It is always desirable that you consult your doctor before taking a Viagra in general. Some of the dangerous factors are:

1 Taking Viagra with nitrate drugs such as nitroglycerin, isosorbide mononitrate, and such others.
2 If you are experiencing an unreasonably high or low blood pressure
3 If you have any kind of a liver disease
4 If you are suffering from a kidney disease that requires dialysis (blood purification process)

Precautions

While taking Viagra, you should always consult a doctor near you. Additionally, you should also follow certain precautionary measures like:

  1. You should avoid buying Viagra online, as there is a high probability that it is fake
 2. You should try going for natural alternatives to Viagra. Studies have shown that the medicines with nitric oxide can help you in having a proper and enhanced erection. Additionally, medicines containing L-arginine are also very popular as they help in generating nitric oxide.



Does Viagra add to the risks of melanoma?

Radiotherapy is a kind of treatment that kills the cancer cells by using high energy beams. Specialists use radiotherapy to treat a wide range of lung cancer. For early stage lung cancer, the radiotherapy may get rid of the cancer totally. For the small cell lung cancer you may have radiotherapy only. Then again you may have it with another treatment, for example, chemotherapy or surgery.

For small cell lung cancer, radiotherapy is used with or after chemotherapy. Chemotherapy makes the tumor in the lung shrink. You may have radiotherapy to your cerebrum, which tackles any cancer cells that may have spread to the brain. This is called prophylactic cranial illumination (PCI). In case of advanced lung cancer, the treatment contracts the tumor and controls it for a while. It additionally decreases symptoms like shortness of breath.

The types of radiotherapy used for the lungs include:

Outer radiotherapy: This kind of radiotherapy comes from a machine and is administered to the body through an external source. It depends on the kind of cancer and the progression of the same. You may have three radiotherapy sittings every day for around 12 days. This sort of radiotherapy is known as CHART ceaseless hyperfractionated quickened radiotherapy. A few people with small cell lung cancer may have treatment twice a day. If you are getting radiotherapy to control the side effects of lung cancer, you may have a single treatment or day by day medications for up to 3 weeks.



Inner radiotherapy: This is called brachytherapy or endobronchial treatment. This will be administered during a bronchoscopy. The radiation is given through a thin tube that the specialist puts inside your aviation route for a few of minutes. Specialists use this sort of treatment to shrink a tumor that is blocking or pushing your breathing track and making breathing troublesome for you.

These are some of the procedures that take place while you are having lung cancer radiotherapy:

Radiotherapy machines are enormous. The machines are fixed in one position or are sometimes ready to go around your body to give treatment from various angles.
Prior to your first treatment, your radiographers will clarify what you will hear and see. The treatment room normally have docks for you to connect to music players. So you can listen to your own choice of music.
You cannot feel radiotherapy when you really have the treatment. It takes anything from one second to a few minutes. It is essential to lie similarly situated every time, so the radiographers may take a short time to get you prepared.
Once you are in the right position, the staff will allow you to sit in the space for a couple of minutes. They watch you constantly on a closed circuit TV screen. They may request that you hold your breath or take shallow breaths during the treatment.
In case you have a concern or query you can always consult an expert & get answers to your questions!

Radiotherapy For Lung Cancer!

Cancer today is not as rare as it once was. Today, cancer affects the young and old alike. One of the reasons for this is the pollution in particular air and water pollution that we are exposed to on daily basis.
The air we breathe in today is a mixture of smoke, particulate matter and noxious gases that causes great harm to our bodies. Amongst these, particulate matter that is smaller than 2.5 millionths of a metre is the worst.

These particle matters are emitted into the air from car exhausts, industrial exhausts, coal fires, wood stoves etc. While the body s natural defences help keep larger particle matter out of the system by sneezing or coughing it out, smaller particle matter enters the body easily. These then get trapped in the lungs and enter the bloodstream. Particle matter has in particular been linked to increasing number of lung cancer cases. Apart from lung cancer, coal tar particle matter has been linked to bladder cancer, soot to oesophageal cancer and benzene and other pesticides to leukaemia.

Radon is another source of air pollution that is emitted from the ground. In some cases, radon can also be emitted through the water. As this gas decays, it releases tiny particles that when inhaled bombard the lung cells with radiation that can cause radiation. Smoking can worsen this effect and increase a person s risk of suffering from lung cancer. Both first-hand and second-hand smoking have also been linked to breast cancer. Apart from trying to reduce emissions to lower air pollution, it is also important to clean filets of air conditions, etc. regularly to lower indoor air pollution. Preventing the smoking of tobacco in public spaces can also help improve air quality.

All pollutants emitted by us eventually find their way into the water we drink. Even if you are not drinking contaminated water, merely, showering or swimming in contaminated water can make your body more vulnerable to the carcinogens in it. Common water pollutants include arsenic, hazardous waste, animal waste, radon, chemicals and asbestos. Drinking water with concentrated amounts of arsenic has been linked to cancer of the lungs, liver, kidney and bladder while the chlorine used to treat drinking water increases the risk of bladder and rectal cancer.

To reduce the risks of cancer caused by polluted water, it is essential to reduce disinfectant by products by keeping water treatment facilities updated and promote green chemistry and alternative assessments to reduce pollution as a whole.

Pollution - How It Has Increased the Risk Of Cancer?

Melanoma is a condition which mainly indicates a severe malfunction of the melanocytes or the melanin producing cells of the body. These cells are responsible for giving you your skin colour, tone and complexion. Usually, a person suffering from melanoma will have many normal and irregular moles as well as melanoma in the eye and digestive tracts too.

Some general facts on melanoma are mentioned below:
Melanoma is common in young women and causes many deaths.
More than one million new instances of skin cancer or melanoma are analyzed every year.
There has been a 2000% increase in rate of melanoma since the year 1930. One out of fifty get affected by this cancer.
There has been a high rise in the rate of melanoma from 1970 to 2008. There has been an 800% increase in young women and 400% increase in case of similar aged men.
Early recognition makes melanoma treatable. It is screened for growth very minimally.
Primary causes Melanoma may be caused primarily due to these causes:
The most primary cause of melanoma is ultraviolet light (UV) in people with a low level of skin pigment. The UV light might be from either the sun or from different sources, for example, tanning devices. Around 25% of cases occur from or in the form of moles.
The individuals who work on airplanes seem to have an expanded danger, due to more contact with UV rays.
Ultraviolet UV light of wavelengths between 315 - 280 nm from the sun react with the skin cell DNA and result in a kind of direct DNA harm called cyclobutane pyrimidine dimers (CPDs).
In order to stay away or avoid melanoma, you should:
Avoid the sun at peak hours.
Examine your skin at times for some kind of change.
Keep away from tanning salons.Melanoma is a dangerous form of cancer and causes a lot of deaths. You should stay away from anything that causes melanoma.


All About Melanoma

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