Irrfan Khan's saddening revelation about his health and diagnosis of Neuroendocrine tumour (NET) has undoubtedly created a rage amongst his fans, which is now being followed by good wishes for speedy recovery from his supporters all across social media.  

The actor shared in an emotional Twitter post that he s been diagnosed with NET, a rare tumour that develops from cells of the neuroendocrine system and grows predominantly in the digestive or respiratory tract - lungs, appendix, small intestine, rectum, and pancreas - it can occur in any part of the body.

Here is more on Irrfan s disease:

What is NET?

A neuroendocrine tumor is characterized by a rapid and abnormal growth that happens in the nerve cells which produce hormones. Hormones control how different organs in the body work.

It is a condition wherein, endocrine cells, the hormone-producing cells of the body, develop a tumor in any part of the body - while it can can grow in lungs or the thymus, or more rarely, in the ovaries, kidneys, or testicles - the most common is lung, intestines, and pancreas.

What causes NET?

A neuroendocrine tumour is quite a rare disease, occurs in less than one per million cases. The exact cause is not known.

The Symptoms-

It can cause a myriad of symptoms, depending on where in the body the NET is.

If it is in your digestive system, it can cause pain or discomfort in the abdomen area that comes and goes. You may feel sick, nauseated, vomited, or there may be a change in how often you pass stools.
If the NET is in the lung, it can cause shortness of breath, chest infections, or you can even have a cough up blood.
Weight loss and loss of appetite may also be some common signs of a neuroendocrine tumour.
Some NETs may overproduce a hormone-like substance called serotonin. This causes a group of symptoms called carcinoid syndrome. Symptoms include wheezing (like asthma), flushing of the skin and diarrhoea.
Who can be affected with NET?

These tumours, depending on the type, are more common in certain age or sex. And few have very strong family history too.
People who have a rare condition called multiple endocrine neoplasia 1 have an increased risk of developing a NET.
Did You Know?

Apple founder  Steve Jobs  died from the same disease in 2011. The tumour affected his pancreas.

Know The Different Types of NET:

Based on the organ that is affected, NET can vary a lot. When the chromaffin cells that produce adrenaline are affected, it is called Pheochromocytoma, and it is related to the stress levels of the body.

When a cell is formed abnormally under the skin and the hair follicles, it is called Merkel cell cancer. This is also called neuroendocrine carcinoma of the skin and the condition can occur anywhere in the body. The commonly occurring places include lungs, gastrointestinal tract, and brain.

The status of the tumour, cancerous (malignant) or noncancerous (benign), decides the survival rate. Often slow-growing and noncancerous, they can invade surrounding parts of the body and at times, turn cancerous and spread across the body. However, you can still choose to live a good quality life with strict modifications in diet and lifestyle. The changes are made after taking into consideration the symptoms of the tumor. The organ where the tumor is formed also matters.

How Is It Treated?

Treatment depends on the location of the tumour, its type, how severe it is and whether it has spread to other parts of the body. Usually, the first treatment choice is surgery to remove the tumour. And, if the NET cannot be removed, your will prescribed with a treatment that will not only relieve the symptoms but will also improve the quality of your life.

How can a NET be prevented?

The first thing you need to do for the prevention of NET is to curb stress. Stress affects the entire body severely.

Lifestyle modifications:

A healthy lifestyle is what you need to stick to if you want to manage its symptoms during the treatment cycle. Your doctor will prescribe you to do exercises at least 4 days a week for a minimum of 30 minutes. You can also try a walk instead of strenuous exercises.

People with carcinoid syndrome may be advised to avoid food or activities that may trigger flushing, such as eating spicy food or drinking alcohol.

Indulge yourself in therapies that help in gaining more positive energy. If you are already affected by NET, eliminate all the sources of stress and get a good night's sleep every day. Join the support groups that make you grow strong and happy. After all, the mind is devised to do miracles when it is full of life and positive thoughts.

Is Irrfan Khan's tumour curable?

Dr Saumitra Rawat, HOD, Surgical Gastroenterology & Liver Transplant, Sri Ganga Ram Hospital, said, "NeuroEndocrine Tumour is an abnormal growth of Neuroendo cells which are present in bodies. When there is an abnormal growth, then it forms a tumor - Normally seen in intestine, pancreas, lung, thyroid and other parts of the body".

On commenting on Khan's case, he said, "It depends on the location of tumour, its size, and what is its mitotic index".

"Depending on where the tumour is localized, you can take it out surgically and the chances of cure are very high", Dr Rawat explained.

Actor Irrfan, who has been diagnosed with the disease is one of the most versatile actors in India, has also made a name for himself in the west, where he has been an important part of critically-acclaimed films such as  The Namesake ,  Jurassic World , and  Life of Pi . At home, the actor has delivered remarkable performances in films such as  Haasil ,  Paan Singh Tomar ,  Maqbool ,  Lunch Box ,  Piku , and the most recent  Hindi Medium .

Irrfan Khan is not just a disarmingly natural actor, but also an endearing human being -- honest and humble to the core. It s time to stand together and pray for him a speedy recovery!

Irrfan Khan - Battle Against Neuroendocrine Tumour!

As much as you want to avoid, there are things you have no control over. Lung cancer (Bronchogenic Carcinomas) is one such nemesis that can throw life in shambles. The malignant tumor that originates in the lungs slowly spreads onto the other distinct and vital organs as well. Thought to be mostly affecting men who are chain smokers and into severe tobacco consumption, incidences of lung cancer in women are rising at an alarming rate over the past few years. Non-smokers may also be susceptible (to a lesser extent though) to lung cancer.

Lung cancer can be either

Non-small cell lung cancers: The NSCLC, accounting for ~85% of the lung cancer is one of the most common types of lung cancer affecting people, NSCLC may further be divided into
Adenocarcinoma: This type of NSCLC originates mostly in the peripheral regions of the lungs and may affect (spread) the lymph nodes. Non-smokers and women are mostly at the receiving end (other than the chain smokers).
Squamous Cell Carcinoma: Also known as Epidermoid Carcinoma, often affects men, epidermoid carcinoma may originate in the tissues that line the bronchial tubes. The lymph nodes are often affected by Epidermoid Carcinoma.
Large-cell Undifferentiated Carcinoma: The point of origin of large-cell undifferentiated carcinoma is the surface of the lungs. They have a higher probability of spreading to the lymph nodes.
Bronchioalveolar Carcinoma: Though rare, bronchioalveolar carcinoma originates close to the air sacs.
Small Cell Lung Cancer (SCLC, accounting for ~25% of the lung cancer): As the name suggests, SCLC is marked by the rapid proliferation of small cells into large malignant tumors. SCLC can move throughout the body (affecting vital organs).
Radiotherapy to treat Lung cancer:
Radiotherapy plays a pivotal role in the treatment of lung cancer. The radiation therapy is mainly of two types

External beam radiation therapy (EBRT)
Internal radiation therapy (Brachytherapy)
In external beam radiation therapy, high-energy rays are focused on the cancer cells (thereby resulting in the apoptosis of the cancer cells) externally, from outside the body. EBRT is particularly helpful in case of Non-small cell lung cancers.

The EBRT may be of the following types

3D-CRT (Three-dimensional conformal radiation therapy): An advanced radiation therapy, 3D-CRT accurately marks the position of the cancer cells (using advanced computers). The treatment ensures minimum damage to the other healthy cells and tissues (energy rays are directed at the affected cells from different positions).
SBRT (Stereotactic body radiation therapy): This is a radiation therapy used in the treatment of NSCLC, when it is at a nascent stage.
IMRT (Intensity modulated radiation therapy): As the name suggests, in IMRT, the intensity of the radiation reaching the normal tissues and cells can be modulated. Like 3D-CRT, the radiation in IMRT is directed from different angles (for maximum results).
Internal radiation therapy (Brachytherapy): This type of radiation therapy is generally used to deal with lung cancers that tend to block the airways. In this therapy, the radiation process is carried out through a narrow tube, thereby, shrinking and collapsing the tumor.
The effect, dosage, and duration of radiation therapy depend on the stage and severity of the condition. In some cases, radiation therapy may be given together with chemotherapy.

Radiotherapy - Is It Beneficial For Lung Cancer?

Lung cancer is the cancer killer of both men and women in the world. When you think of risk factors for lung cancer, what comes to mind? Most of us think about the risk associated with smoking cigarettes, but did you know that air pollution can also cause lung cancer? Overwhelming evidence shows that particle pollution in the outdoor air we breathe like that coming from vehicle exhaust, coal-fired power plants and other industrial sources - can cause lung cancer. Particle pollution increases the risk of dying early, heart disease and asthma attacks, and it can also interfere with the growth and function of the lungs. 

What is Particle Pollution?

Particle pollution is a mix of tiny solid and liquid particles in the air and can be made up of a number of components, such as acids, organic chemicals, metals, soil and dust particles. It can be emitted directly from wood stoves, forest fires, vehicles and other sources, and it can also form from other types of pollution that come from sources like power plants. 

Why does particle pollution harm our bodies?

While breathing in larger sizes of particle pollution can be harmful to our health, smaller particles are more dangerous. Bigger particles can irritate your eyes, nose and throat, but our natural defenses help us to cough or sneeze them out of our bodies. Unfortunately, those defenses don't keep out smaller particles, which get trapped deep in the lungs and can even get into the bloodstream, causing damage to our health.



Who is most at risk?

As for who is at risk for health problems from breathing in particle pollution. Those who live where particle pollution levels are high is at risk. Some people face higher risk, including children, the elderly, people with lung and heart disease and diabetes, people with low incomes, and people who work or exercise outdoors.

How do we protect ourselves from particle pollution?

Check the air quality index forecast for the day and limit your activity if pollution levels are high. Avoid exercising along heavily traveled highways regardless of the overall forecast.

As individuals, we can play our part in reducing air pollution levels by trying to avoid creating more of it. Choosing  active travel  options where possible, like walking and cycling, can help reduce pollution levels from transport and is also a great way to be more active, which is linked to a reduced risk of cancer and other diseases. In case you have a concern or query you can always consult an expert & get answers to your questions!

The Connection Between Lung Cancer & Outdoor Air Pollution!

Lungs are very important organs of your body as they play a pivotal role in respiration. Lung cancer refers to the gradual development of cancerous cells in the lungs. Many common symptoms can help you to identify lung cancer. They are stated below:

A) persistent cough
B) change in your voice
C) pain in the chest region
D) breathing problem
E) fatigue
F) loss of weight and appetite
G) sometimes a person may also cough up blood
H) cough accompanied by a wheezing sound

Lung cancer is very fatal and has less chances of getting cured. However, ayurveda offers effective and natural remedies for treating lung cancer. They are mentioned as follows:

1. Practice breathing exercises regularly: breathing exercises can help you to deal with the problem of lung cancer in an effective manner.

2. Quit smoking and avoid drinking alcohol: this is absolutely essential for treating lung cancer. Both smoking and consuming alcohol can cause severe damage to your lungs.

3. Practice meditation. According to ayurveda, meditation is known to have great healing powers for any health problem. This can help you to cope up with cancer as well.

4. Avoid junk foods and carbonated drinks: consuming these foods frequently can worsen your condition.

5. Massage therapy: sometimes massage therapy can work wonders in ayurveda. Massaging certain essential oils can be very helpful.

6. Aromatherapy: aromatherapy can also prove to be effective in treating lung cancer. It is a procedure in which essential oils are not only used for massaging your body but also for inhaling.

7. Ayurvedic herbs: there are many ayurvedic medicines and herbs also which can treat lung cancer efficiently.

Since lung cancer involves very less survival rate, it is of utmost importance that you go the doctor immediately once you start noticing any of the above mentioned symptoms.

Treating Lung Cancer With Ayurveda

Skin cancer most often develops on skin that has faced sun exposure. At the same time, it can also affect skin areas that haven't been exposed to sun's rays. Do you know, skin cancer can be prevented by consuming some foods? Yes, and there are some out there:

1. Fatty fish - Including fatty fish in your diet can shield you against melanoma as they contain the beneficial nutrient Omega-3 fatty acids. In fact, these kinds of fatty acids are considered to be best for consumption as unlike saturated fats, they don't increase your risk for certain types of cancer. A study in the International Journal of Epidemiology reveals that individuals who consume a diet containing fish that is high in these healthy fats have low rates of this form of cancer.
2. Vegetables - This is another food option that is known to possess strong skin cancer-fighting properties. Dark leafy veggies like spinach, kale and broccoli can aid fighting against melanoma. A pigment found in tomatoes called lycopene has properties that guard you against cardiovascular diseases as well as cancers of all kinds. Similarly, the pigment carotenoids found in vegetables like carrots, sweet potatoes, etc are known to protect against sunburn.
3. Herbs - Including herbs in your diet can help in replenishing the minerals and vitamins that get depleted due to the action of the sun. According to experts, about 80% of your body's vitamin levels see a reduction when you stay under the sun for 30-45 minutes. Basil, parsley, and rosemary are a few of the herbs that possess cancer-fighting qualities.
4. Flaxseeds - The unique qualities of flaxseed make it the best option against skin cancer. It contains both antioxidants and omega 3 fatty acids, making it an all-around solution to fighting skin cancer.

4 Foods That Help Fight Skin Cancer

How to become less prone to cancer

There are various known reasons why cancer takes root in a healthy body. The deadly disease takes away millions of lives worldwide and remedies in food to tackle it are constantly a subject of research. However taking this one food item off your daily diet can help becoming less prone to cancer.

Senior cancer experts stress that sugar feeds cancer. According to his belief, backed by years of research and medical expertise, it is possible to starve cancer out of a person’s body. When sugar breaks down in the body in a non-oxidative manner, adenosine triphosphate (ATP) is generated which causes cancer cells and tumor to grow.

Research states that cancer is a dysfunction of the mitochondria caused by fermentation of sugar in the cells instead of orthodox respiration of normal cells. This can be tackled by limiting the supply, just by cutting down the intake of sugar every day. A small amount of sugar in a healthy and requisite proportion is acceptable but excessive sugar must be avoided in order to choke cancer out from the body.

Specifically, the intake of sugar in processed foods must be cut down. Everything that is sweet isn't sugar! Avoiding processed foods will simply eliminate the bad salts and bad sugars from your diet. Eating at fast food joints too must be cut down completely as the food they serve is frozen and needs a lot of preservatives. You can always switch to fruits if you have a sweet tooth. Diet-wise, consume more green leafy vegetables, developing a plant and natural nutrient based diet is an ideal method to tackle cancer.

If you would like to consult with me privately, please click on 'Consult'.

From Lybrate: If you found this tip useful, please thank the doctor by clicking on the heart icon below. Also, spread good health by sharing this tip with your loved ones over WhatsApp, Facebook and other media.


Are You Aware That You Are Feeding Cancer Daily?

Don't wait any longer, manage your Gynaecologic Oncologist online with a Lybrate doctor today

Consult for Gynaecologic Oncologist - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES