Alzheimer s disease is a neurological, irreversible, progressive brain disorder. It is a chronic neurodegenerative dementia that causes the death of brain cells, causing memory loss and cognitive decline. It affects a person s thinking and behavior. The symptoms develop slowly and get worse as time passes.

Causes:
As it is a kind of dementia, Alzheimer s is caused by the death of brain cells. Over a course of time, brain cells die progressively and at the end, the tissue is left with fewer nerve cells and connections. As a result, the total brain size shrinks. Tiny inclusions called plaques and tangles can be seen in the postmortem. These cannot be seen or tested in a living Alzheimer s affected brain. These plaques are given the name  amyloid plaques  because they are found among the dying cells of the brain when a protein called beta-amyloid builds. The tangles stay in the neurons; they are formed from a protein called tau.

There are several reasons behind all this, some of which are listed below-

Anti-anxiety medications
Hitting on the head too many times
Regularly sleep-deprived
Loneliness
Diabetes in the brain
Old age
Genetic line
Down s syndrome
Cardiovascular diseases
Symptoms:
Alzheimer s disease damages the brain, so the clinical signs and symptoms begin to show very early. The symptoms are-

Memory loss
Agitation and mood swings
Poor judgment
The trouble with money calculations
Difficulty doing familiar tasks
Trouble in planning or solving a problem
Confusion with time and place
Difficulty in communicating
Loss of motivation
Inappropriate behavior
Aggressive personality
Childlike behavior
Preventing Alzheimer s disease:
Alzheimer s disease ultimately results in death. Even if there are treatments, they cannot fully cure it. So it s better to try to prevent it before it happens. Ways to prevent Alzheimer s disease are-

Eating more fruits and vegetables.
Eating berries every day.
Increasing omega-3 fatty acids.
Taking folic acid supplements.
Drinking grape juice or red wine with evening meal.
Doing the Mediterranean style diet.
Controlling the blood pressure.
Having strong social support.
Treatment of Alzheimer s disease:

Treatment of Alzheimer s disease is a long time process.
First of all, doctors perform a physical exam to check the overall neurological health. By this, they check muscle strength, reflexes, walking ability, sense of sight and hearing, coordination and balance.
Then comes the blood test to find the cause of confusion and memory loss by checking the thyroid disorder and vitamin deficiency.
Then they perform the neuropsychological test and check the mental status.
Then there are other tests, like MRI, CT, and PET.
After all this, drugs are given and a safe and supportive environment is created with proper exercise and nutrition.
Alzheimer s disease is undoubtedly the worst kind of disease. Hence, it is highly recommended to contact a doctor as soon as any symptom is noticed.

All About Alzheimer's Disease!

Proper rest and a sound sleep are prerequisites for keeping the physical and mental health in good shape. Difficulty to fall asleep or having a disturbed and interrupted sleep day after day can be a nightmare. In addition to the immense physical exhaustion and fatigue, insomnia can leave a person stressed out mentally which is bound to have an impact on their professional as well as personal lives and commitments. Over the last few years, incidences of insomnia have been rising at an alarming rate.

Insomnia does not always exhibit similar symptoms in all the affected individuals. In some, the condition may be short-term, lasting for a few days or weeks (Transient Insomnia). In some, the problem may appear on and off (Intermittent Insomnia). In extreme cases, insomnia and the associated discomfort may continue for months (Chronic Insomnia). In some instances, insomnia appears as a symptom associated with health conditions such as diabetes, Alzheimer's disease, Parkinson's disease, heart ailments, GERD, to name a few. Severe stress and anxiety along with unhealthy dietary and lifestyle habits are also known to play a pivotal role resulting in insomnia.

The goodness of Unani in treating Insomnia
Unani is one of the ancient forms of medications that has gained immense worldwide appreciation due to its effectiveness in treating various threatening and complicated health conditions including insomnia. In case of Insomnia, the Unani treatment involves a combination of Dietotherapy, Regimental Therapy, and Pharmacotherapy. The main aim of the Unani treatment is to treat insomnia by restoring the balance between the four humors namely, Blood (Dum), Yellow bile (Safra), Phlegm (Balgham), and Black bile (Sauda). It is these four humors that not only nourish the body and the vital organs but also keeps the various health conditions at bay.

With Dietotherapy or Ilaj Bil Ghiza, the aim is to bring the necessary dietary changes to deal with insomnia. The daily intake of banana, walnuts, kale, lettuce leaves, sweet potatoes, herbal tea (especially Chamomile), grapefruits, turkey and red meat (in moderation), whole grains, go a long way to improve the condition of insomnia. People with insomnia should, however, try and avoid processed foods, cheese, pork, aerated, caffeinated and alcoholic drinks, as much as possible. Unani also suggests that the dinner should be light and taken at least 2-3 hours before going to sleep.

Pharmacotherapy or Ilaj Bil Dawa involves the use of Unani medicine to alleviate the discomfort. Some of the medicines often used in treating insomnia includes:

Rogan Kaddo
Rogan Badaam
Hareera Magaz Badaam
To treat insomnia, a Unani specialist will also carry out a detoxification of the body, known as Regimental Therapy or Ilaj Bil Tadbeer, the detoxification is brought about through

Exercise (Riyazat)
Massages (Dalk)
Leeching (Taleeq-e-Alaq)
Venesection (Fasd)
Turkish bath (Hammam)

Role Of Unani Medication In Insomnia Treatment

One of the common ailments in the elderly people is the Parkinson s. A progressive disorder, when left untreated, results in worsening of the symptoms. Hence, it is essential to understand the treatment options available to manage the condition effectively. You may be suggested surgical therapies if medication is not effective enough to treat the symptoms.

Surgical treatment options can be beneficial for patients who are suffering from symptoms, but they do not help with treating the disease. In the past, surgical methods like Thalamotomy and Pallidotomy were used to destroy brain cells that contributed to the symptoms. While these methods are still used, they are very rare and situational.

Deep Brain Stimulation (DBS), an FDA-approved procedure, has become much more popular as it is much safer and does not involve invasive surgery. Instead of destroying brain cells like traditional methods, DBS involves sending electric pulses to the affected brain cells to reduce the symptoms. It is not a treatment procedure, but a means of bringing down the severity of Parkinson s to allow better and more comfortable treatment.

Deep Brain Simulation   Who are the right candidates?
Deep Brain Simulation is commonly used for Parkinson  s disease, but it is not recommended for everyone. It is a preferred method of treatment for people who have had Parkinson s for at least four years but have complications which include long periods of time where medications do not work, or symptoms return, uncontrolled and involuntary movements or the freezing/stiffness in the body.

Deep Brain Simulation is not recommended for those who have Dementia as it can lead to memory problems. The general rule of thumb that neurosurgeons follow is that Deep Brain Simulation can help with symptoms that do not get better with medication. DBS can help reduce medication requirements for patients as well as reduce the side effects that may occur due to medication.

Disorder specialists and neurosurgeons can conduct tests to determine if DBS is going to be effective for a patient before going ahead with such a procedure. An extensive assessment is necessary to understand the symptoms, the effect of Parkinson's drugs and also brain imaging is done. All of the expected benefits are then evaluated for the patients, and if the procedure can help alleviate the symptoms, DBS is given a green signal by neurosurgeons and patients can undergo the procedure.

How Does Deep Brain Simulation Work?
Deep Brain Simulation is a very complex procedure. Brain cells communicate with the rest of the body through electric signal, and these become irregular and do not work properly when affected by Parkinson's. DBS smoothens the functioning of these brain cells and reduces symptoms through electric pulses through the implantation of a medical device known as neurostimulator which is also referred as brain pacemaker.

But, as with any treatment procedure, DBS has potential risks and side effects, hence discuss with neurosurgeon thoroughly to access the suitability.

Adopting Deep Brain Stimulation For Parkinson's disease

With age, most body organs begin to deteriorate in their function. This happens to the brain also, thereby reducing the overall speed of functioning of most organs. While slowing of bodily movement is visible, the internal organs functioning also slows down, which is not that obvious. Memory loss or dementia is one of the main manifestations of this degeneration of the brain.

Alzheimer s is the most common form of dementia, and the associated symptoms includes reduced reasoning abilities and cognitive defects. Though it is seen only in the elderly, not all elderly people will have Alzheimer s. The overall quality of life of the affected person is reduced with difficulty remembering things that were recently learned. It is a progressive disease and as it gets more severe, a full-time caretaker may be required.

Causes: The brain cells are affected by protein masses known as plaques and tangles. These hamper the way communication between the brain cells happens as well as affect nutrition from reaching all parts of the brain. This leads to shrinking of the brain, eventually leading to memory loss and other problems. There is also a strong genetic linkage, as most people with Alzheimer s have the lipoprotein A gene.

Symptoms: Though memory loss is the most common symptom, there are other symptoms:

Being confused about places, people, and times
Inability to find the right words during conversations
Regular objects are misplaced
Becoming irritable, (in someone who was not so previously)
Mood swings
Personality changes
Inability to organise thoughts
Not able to make the right decisions
Repetitive talks and actions
Forgetfulness (not something the person always does)
Difficulty with numbers (again, not something calculations
Difficulty managing everyday tasks and minor problems
Suspicion of others (like immediate family members and friends)
Risk factors: While age is definitely a risk factor, the fact that not all aged people develop Alzheimer s is to be borne in mind. Other risk factors include the history of stroke, high cholesterol, high blood pressure, diabetes, smoking, obesity, and poor lifestyle choices.

Diagnosis: While there is no definitive way to diagnose Alzheimer s, symptoms along with brain scans and neuropsychological function testing are useful ways to confirm the diagnosis.

Treatment: This is aimed at two things reducing the rate of disease progression and treat (or reverse) symptoms if possible.

Cholinesterase inhibitors improve cellular communication in the brain and also manage depression and agitation. Memantine is used to slow the pace of disease progression.
In people with the disease, small changes are useful to help them with the symptoms. These include keeping essential things like keys and wallet in the same place, keep a daily diary to help them remember things, keep pictures of friends and family within visible distance.

Alzheimer's - An Overview!

The brain contains numerous nerve cells which help in its normal functioning. Epilepsy or seizures occur when there is a disruption in the activity of the nerve cells in the brain. A neurological disorder of the CNS (Central Nervous System), epilepsy can affect all and sundry, irrespective of their age, sex and ethnicity. However, children and aged people (above 60 years) are more susceptible to the condition. A study suggests approximately 10 million people in India suffer from epilepsy.

Types of Epilepsy
Based on the activity of the brain that causes an epileptic attack, Epilepsy can be of two types - Focal or Generalized
Focal Epilepsy: An epileptic attack triggered by unusual activities restricted to a particular area of the brain.

In some cases, focal epilepsy may result in unconsciousness. A person may also lose awareness and become unresponsive (keeps staring into space), a condition termed as Focal Dyscognitive Seizures. A person with this condition may behave strange, such as walking in circles, chewing or rubbing their hands.
In another type of focal epilepsy known as Focal seizures without loss of consciousness, a person does not lose consciousness. In such cases, there may be sudden and involuntary jerking of the arms or the legs. There may also be dizziness or a tingling sensation.
Generalized Epilepsy: Here, the seizures or epilepsy result from unusual activities throughout the brain. Generalized epilepsy, may, in turn, be of the following subtypes

Tonic seizures: This affects the muscles of the legs, arms, or the back, causing them to stiffen and tighten up.
Atonic seizures: Here, a person may suddenly fall down due to loss of muscle control. The condition is also known as Drop Seizures.
Absence seizures: Mostly affecting children, the affected person may lose awareness (temporary) and behave strangely such as staring into spacing, smacking their lips, or blinking their eyes continuously.
Clonic seizures: They are characterized by sudden and continuous jerking movements of the arms, face, and neck muscles.
Tonic-clonic seizures: Here, a person may suddenly lose consciousness. There are violent shaking and stiffening of the body. Some people may even be seen biting their tongue.
Myoclonic seizures: In this arms, and legs of a person suddenly twitches and jerks.

What triggers an Epilepsy?
Epilepsy may be an outcome of the following factors

Medical conditions such as stroke or even brain tumors may affect the normal activities of the brain, thereby resulting in epilepsy. Diseases such as Viral Encephalitis, AIDS or Meningitis act also act as a trigger, accelerating the chances of epilepsy.
Developmental disorders such as Neurofibromatosis or Autism can also trigger epilepsy.
In some cases, epilepsy may be a genetic predisposition. Thus, a person with a family history of epilepsy may suffer from the condition.
Epilepsy may also be an outcome of a prenatal brain injury due to oxygen deficiency or an infection to the mother.
People with dementia may also suffer from an epileptic attack.

Epilepsy - Know The Most Common Types!

Migraine headache is characterized by a severe headache usually affecting one side of the head. There are other symptoms along with headache like nausea/vomiting, sensitivity to light and sound. Some patients experience neurological phenomena like changes in vision, temporary loss of sensation and altered sensation, a phenomenon known as an aura (flashes of light, zigzag patterns, bright spots, tingling in the arms and the legs). Migraine headache can last for 2 to 3 days. 

Symptoms: The symptoms depend on the stage of a migraine attack. The stages of a migraine attack can be: 

Prodrome, Aura, Headache or attack, and Postdrome. 
Prodorme: One to two days prior to the migraine attack, patient may experience; 
Mood swings. 
Cravings for food. 
Increased yawning. 
Stiff neck. 
Constipation and frequent thirst and urination. 
In case of an aura (during or before a migraine), there may be visual, motor, speech, and sensory illusions and disturbances such as, 

Loss of vision. 
A strange sensation of needles pricking an arm or a leg. 
One side of the body becomes weak and numb. 
There are visual illusions such as the appearance of flashes of light, zigzag patterns, bright spots. 
There is a problem in hearing and speaking. 
In some cases, there may be a hemiplegic migraine (the limb becomes weak). 
During a Migraine Attack (lasts for 4 to 72 hours), there may be 

A throbbing pain on either one or both sides of the head 
Blurred vision, light-headedness. 
Nausea and vomiting 
Sensitivity to light and sound 
Sensitivity to touch and smell (though rare) 
In Postdrome (after a migraine), there can be 

Mood swings. 
A person may be sensitive to light and sound. 
Dizziness and weakness 
Confusion 
Extreme fatigue 
An amalgamation of environmental and genetic factors may be responsible for a migraine. Trigger varies for each patient: 

Stress and extreme physical exertion 
Obesity 
Alcohol and caffeinated drinks and beverages 
Salty and processed foods 
Altered sleeping habits 
Hormonal alterations in women (Constant fluctuation in the level of oestrogen) 
Oral contraceptives and certain vasodilators (nitroglycerin) 
Preservatives like MSG (monosodium glutamate) and Aspartame (sweetener) 
Sunshine, certain odours, travel, etc can trigger migraine. 
Treatment and Prevention: 

Medicines under supervision to abort an attack of migraine and special drugs to stop attacks. 
Lifestyle changes are helpful to decrease attacks: 
Avoid your trigger for migraine. 
Follow regular sleep -wake cycle. 
Regular exercise, meditation. 
Avoidance of alcohol, caffeine containing beverages. 
Other treatment options that can be availed from pain specialist: 
Transcutaneous supraorbital nerve stimulation 
Intramuscular stimulation. 
Botulinum toxin injection. 
Occipital nerve block.

Migraine Pain - Facts About It!

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