Autoimmune disorders are one of the least understood disorders in the whole of medical science. Systemic Sclerosis is also an autoimmune disorder in which the skin undergoes changes in texture and characteristics. 

However, the changes are not confined to the skin alone. It can affect blood vessels, muscles, digestive system, heart, kidneys, as well as the lungs. It typically affects people in the age group of 30 to 50 years, but the good thing is that doctors can diagnose this at any age. 

It has been observed that more women fall prey to this disorder than men. The severity of symptoms may also vary from person to person. Nevertheless, the real cause of worry is the progressive nature of the disease. Due to this, it is, in fact, sometimes referred to as Progressive Systemic Sclerosis. 

Causes of Systemic Sclerosis 

It is an autoimmune disorder in which the immune system attacks the skin and precipitates the problem. The attack by Immune System precipitates increased collagen production in the body, which accumulates in the skin tissue. This leads to changes in characteristics and the appearance of the skin. 

Symptoms of Systemic Sclerosis 

Systemic Sclerosis affects only the skin in the early stages. It may lead to thickening of skin and development of shiny areas around bony areas, such as nose, mouth, fingers etc. However, as the disease progresses, it may limit movement of these affected areas. So one may have a problem in opening the mouth, parting fingers etc. 

Other symptoms are: 

  Loss of hair 

  Deposit of lumps under the skin 

  Blood vessels under the skin getting dilated 

  Pain in the joints 

  Breathing difficulties 

  Dry cough 

  Constipation 

  Diarrhea 

  Swallowing difficulty 

  Reflux of food from esophagus 

  Feeling of bloating after taking meals 

In addition to the above, one may also sometimes experience spasms in the blood vessels of fingers and toes. Legs and hands may turn blue or white if a person is undergoing emotional stress or is in extreme cold. This is also known as Raynaud s phenomenon. 

Risk Factors

Though the causes of the disease are not yet known, there are some risk factors which can make a person susceptible to this disease: 

  If a person is undergoing chemotherapy with certain drugs like Bleomycin or are exposed to stuff like silica dust, organic solvents etc., one may become susceptible to this disease. 

  Women are more prone to acquiring this disease than men. 

  If a person is a Native American or an African-American then too he/she is more susceptible to this problem. 

Treatment of Systemic Sclerosis 

Systemic Sclerosis can t be cured, but its symptoms can certainly be reduced to some extent. So, treatment is specific to symptoms one is experiencing, and may include using the following: 

  corticosteroids 

  immunosuppressants 

  nonsteroidal anti-inflammatory drugs 

  blood pressure medication 

  aid to resolve breathing difficulty 

  physical therapy, light therapy etc. 

The fact that this disease really can t be fully cured makes this a pretty scare disease. Silver lining is that medication and other treatment options are able to suppress most of the symptoms.

Systemic Sclerosis - What Causes It?

Staying up late at night intentionally is not insomnia. If you find it difficult to fall asleep, or cannot sleep soundly for long, then it is indeed a case of insomnia. The inability to sleep can have terrible repercussions on your physical and psychological health.

A number of reasons could cause insomnia. Understanding the causes could help you identify your sleeplessness as insomnia and seek treatment right away.

What Health Issues cause Insomnia?

Here are some health problems of both the mind and body that can keep you awake  

  Stress Chronic stress and worry born out of our tense lives is a direct cause of insomnia. Long-term anxiety, panic disorders, as well as PTSD can induce sleeplessness.

  Irregular Sleep Patterns Your body would hate it if you deviate from the Circadian Rhythm   the body clock. It regulates the functions of your body, including your sleep patterns. But if you defy your body clock by sleeping at irregular hours   suppose you are staying up late to get some extra work done, or you may have opted for a night shift, or if you are experiencing a jet lag   then you will notice that when it is finally time for you to hit the bed, sleep will be elusive.

  Depression Depression is a horrific psychological disorder that makes a person lose interest in life itself. And one of the indicators of depression is loss of sleep. It is not just depression, but also other illnesses that cause psychological turbulence such as bipolar disorder and obsessive-compulsive disorders, triggering insomnia.

  Breathing Issues Sleep apnoea is a dangerous disorder that stops your breathing multiple times every night and will wake you up every time. Yet you will possibly not even remember waking up. However, this does disturb the quality of your sleep and affects your health adversely.

  Dementia Dementia is accompanied by a gradual loss of memory. But sometimes people who are suffering from dementia display anxiety, restlessness or even aggressive behaviour when it is time for them to go to bed. This is called the sundown syndrome and it might even keep them up all night.

  Pain Pain is one of the commonest reasons for losing sleep. Pain can originate due to any number of reasons   arthritis, a sprained joint, an injury, or if you are undergoing chemotherapy or radiotherapy, then it may keep you awake at night. This is actually a vicious circle because the inability to sleep will aggravate your pain. Talk to your doctor who will prescribe the appropriate pain medication.

  Parkinson s disease This disease is another reason behind insomnia. Parkinson s disease interferes with your nerve signals and this might cause disruption in your sleep.

  Menopause When a woman inches closer to her menopause, her body reduces the production of oestrogen and progesterone. This imbalance of hormones can trigger sleep loss.

How long can you go without sleeping?

There is no data on how long a human can function without sleep. The longest someone stayed awake is 11 days. Usually, the body cannot last that long without some sound shut-eye. Your brain flushes out the waste matter its cells produce during sleep. That is why even 24 hours without sleep can make your brain sluggish and disoriented. If you stay awake for more than 48 hours at a stretch, your cognitive abilities will start failing you. Sleep is instrumental to a healthy mind and body. If you are experiencing insomnia, talk to a doctor immediately or look up some remedies.

Health Problems That Keep You Awake!

Asperger's Syndrome or Asperger's Disorder is a neurotypical condition that affects the development of the child the effects of which continue into adulthood. This condition typically shows up as difficulties faced by the patient when it comes to social interactions as well as other nonverbal means of communication. It should not be confused with autism as the patient has no speech and cognitive development delay. 

Asperger's syndrome can show up as restricted and repetitive patterns in the behaviour of the patient. It lies at the higher end of the autism spectrum and the signs are usually less obvious. Here are a few ways with which you can effectively deal with someone who is suffering from this disorder.

1. Routine: The patient suffering from this condition will need a certain kind of stability as it is very difficult to predict what will happen in the near future or to even plan for it. The best way to tackle this scenario is with the help of a proper routine that can help the patient achieve some kind of control over the situation surrounding him or her so that he or she is better equipped and more capable of handling normal functioning and social situations as well.

2. Information: It is also a good idea to help these patients in looking at and in processing information. While normal people may easily be able to discard insignificant or unimportant information, the brain of the patient suffering from asperger's syndrome does not allow him or her to do so. In many cases, the patient is not able to filter the important and the unimportant information. This can debilitate many functions. So, it is important to be present to help the patient in making decisions and processing information that is actually relevant to his or her functioning.

3. Learning: One of the most crucial things to remember with the Asperger's patient is that they tend to understand and process things when they have a visual presentation rather than being told verbally. So showing them things practically in the proper manner is the right way to help them learn and process situations in a correct way. This will prevent them from doing things in the same old way even when their brains tell them that it will lead to wrong results.

4. Physical Abilities: Poor motor skills as well as lack of proper organisation skills are traits that usually characterise these patients. It is important to make them aware of this during games and activities that require management as well as use of social skills. For example, football and other such activities can be introduced in the routine. This will promote interaction with the team in order to play and enjoy the game.

How to Deal With a Patient Suffering From Asperger's Syndrome?

Parkinson s disease is a disorder involving the nervous system. It can start with a mere tremor of one hand and advances to slow movement and stiffness. The face might show little no symptoms in the beginning but the speech might become slurred. With every passing day, the condition worsens. This condition has no permanent cure but the symptoms can be improved with proper medication.

What are the symptoms?
Some unmistakable symptoms include the following:

A sudden shaking of the limb. A sudden tremor of the hand is a very common symptom of this disease.
Stiffness of the muscles that can limit the range of motion and sharp pain.
The posture of the body might get compromised. Often balancing problems are witnessed among many patients.
There could be problems with speech leading to soft, slurry or quick speech. The speech in some cases can become monotonous devoid of inflexions.
Parkinson s disease can lead to slow movement and makes performing of simple tasks difficult.
Patients often find writing very difficult
What are the possible causes of Parkinson s disease?

Specific genetic mutation can lead to Parkinson s disease in folks who have a family history of Parkinson s disease. Certain variations of the gene increase the risk of this disease
Exposure to certain environmental factors or certain toxins can trigger Parkinson s disease in an individual.
Certain cells in the brain known as Lewy bodies can trigger Parkinson s disease.
A certain kind of protein cells within the brain known as alpha-synuclein can trigger the Parkinson s disease in an individual
What are the risk factors?

Heredity: Having an immediate family member or close relative suffering from Parkinson s disease can increase the risk of getting this disease in an individual
Age: Although not a prime risk factor, but an individual over the age of over 60 have an increased risk of getting this disease
Toxins: Exposure to pesticide or certain herbicide increase the risk of Parkinson s
Sex: Men are more likely to get Parkinson s disease than women
What is the medication for Parkinson s disease?

Carbidopa-levodopa: This is a natural chemical that gets passed to the brain and is converted to dopamine by the body. The benefits of this medication might reduce with increased symptoms.
Carbidopa-levodopa infusion: A popular drug in this category is known as the Duopa. It is administered directly into the small intestine in the form of gel through a feeding tube.
MAO-B inhibitors: Drugs from this group include rasagiline and selegiline. This is powerful medicine. Many patient experiences hallucination during the initial days of consuming these drugs.
Anticholinergics: This medication is mainly used to counter tremors of the limbs in the early stage of Parkinson s disease.

Parkinson's Disease - Know The Risks Involved!

Epilepsy is a disorder in the central nervous system characterized by recurrent seizures. An unexpected rush of electrical activity inside the brain leads to a seizure. Brain activity becomes abnormal and leads to periods of unusual behaviour with loss of awareness at times.

Seizures do not always include unusual muscle movements or convulsions. Untreated seizures can seriously affect the lives of children having them. Epilepsy affects both men and women regardless of their ethnic background and age.

Signs of Epilepsy:

A staring spell
Momentary bewilderment
Loss of consciousness
Jerking movements of arms and legs.
Panic or anxiety
Kinds of Seizures:
Seizures are normally classified as focal or generalized depending on the commencement of abnormal brain activity.

Focal (partial) seizures result from abnormal activity in a particular area of the person's brain. Simple partial seizures may change emotions or the way things smell, appear, feel, sound or taste. It is characterized by tingling and dizziness.
Complex partial seizures or focal seizures with impaired awareness entail a modification of or loss of awareness and consciousness. Repetitive movements are performed during such seizures such as hand rubbing, walking in circles or swallowing.
Thorough testing is needed to differentiate epilepsy from other neurological disorders such as narcolepsy, migraine or mental illness.

Generalized seizures normally affect all areas of the brain and consist of:

Tonic seizures lead to muscle stiffness and normally affects muscles in the person's back, legs and arms.
Atonic seizures or drop seizures lead to a loss of muscle control which makes a person abruptly collapse or fall down.
Myoclonic seizures are visible as short jerks or twitches of a person's arms and legs.
Clonic seizures are characterized by repetitive or rhythmic jerking muscle movements.
Tonic-clonic seizures cause sudden loss of consciousness, quivering and body stiffening.
Absence seizures might take place in clusters and lead to momentary loss of awareness.
Symptoms of Epilepsy:
The main symptoms of epilepsy are seizures and it differs from one person to another.

Symptoms of Focal (partial) seizures include:

Dizziness
Change or modification in the sense of smell, taste, hearing, sight or touch.
Twitching and tingling of limbs.
Symptoms of Complex partial seizures include:

Unresponsiveness
Staring blankly
Performing repetitive movements
Loss of awareness or consciousness
Genetics may provide a person with a natural seizure threshold as a person who is susceptible to seizure triggers is said to have inherited a low seizure threshold. A higher threshold conversely makes a person less liable to have seizures.

Epilepsy is a comparatively common neurological disorder that affects innumerable people worldwide and treatments range from medication to surgery.

Epilepsy - Signs and Symptoms You Must Know!

Sleep problems, which can be defined as a sleeping pattern where the parents are unsatisfied, are one of the leading concerns of parents. Children should get a minimum nine hours of sleep so that their health and brain development can occur. Sleep problems can affect not only their health, but also their social and school life. Any interruption or abnormality in a child's sleeping patterns should be examined by a doctor and parents should make necessary efforts for knowing the actual causes of sleep interruption of their kids.

What are the causes of sleep disorders in children?

    Injuries and accidents
    Behavioural troubles
    Overeating
    Slow-reaction times
    Performance problems
    Mood problems
    Learning, concentration and memory troubles

Commonest signs of sleep troubles in kids:

    Difficulty in falling asleep
    Occurrence of unusual events at the time of sleeping like nightmares or sleep-walking
    Snoring and breathing pauses
    Difficulty in staying awake in daylight
    Daytime performances can be adversely affected

Best methods for dealing with sleep disorders in children:

    Regular bed-timing should be sincerely maintained at night.
    Relaxing routine for bedtime needs to be followed,including story-book reading, getting warm bath and others.
    Noise in the house, especially at night, should be minimized so that unwanted disturbances can be eliminated.
    If the room temperature is pretty comfortable, then your kids can sleep peacefully.
    Giving caffeine in excess quantity, especially before sleeping, should be reduced otherwise the kids will not sleep well.
    Meals should not be provided just before bedtime; rather they should be taken a few hours before sleeping.
    If your kids are so very addicted to different electronic gadgets or devices like telephones, televisions, computers and others, then they might face sleeping troubles. Thus, it is your duty to keep your kids away from this kind of addiction.
    If your kids are too very tired, then do not keep them awake forcibly; rather you should make them sleep immediately so that they can get a relaxed sleep at night.

If you think that sleep disorder has become a serious issue with your kids as well, then nothing can be a better option than consulting any health physician. They can best analyse the underlying cause of this issue with your kids.

How to Deal With Abnormal Sleep Behaviour in Children?

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