Renal Tubular Acidosis is a medical condition. When the kidney is unable to acidify urine, it leads to the accumulation of acid in the body. Usually, when blood is filtered by the kidney, it passes through the tubules of the nephrons (the functional unit of the kidney).

Before it flows into the bladder from the kidney, the urine undergoes an exchange of salts, acids and other solutes. Renal tubular acidosis results in the formation of excessive amounts of acid because the kidneys cannot drain them. This may happen because the kidneys cannot reabsorb the alkaline bicarbonate ions from the urine in the early segment of the nephron or because of inadequate production of acidic hydrogen ions in the latter half of the nephron.

Renal Tubular Acidosis is simply associated with abnormal urinary acidification. Other functions of the kidneys remain unimpaired.
There are several different types of renal tubular acidosis-

  Distal Renal Tubular Acidosis (RTA)
This is the most fundamental form of RTA. It is characterized when the hydrogen ions are not secreted into the lumen of the nephron by the alpha-intercalated cells of the medullary collective duct of the distal nephron. When this happens the pH of urine cannot be brought down below 5.3. Renal excretion is inhibited and hydrogen ions are not eliminated which leads to academia. At the same time, Potassium ions cannot be absorbed by the cell which leads to hypokalemia. The end result is protein retention and potassium excretion. Distal RTA can lead to the urinary stone formation, calcium deposits in the kidney, rickets and osteomalacia and Sjogren s syndrome.

  Proximal RTA
When proximal tubular cells reabsorb 85% of filtered bicarbonates and 60% of filtered sodium from the urine, then this again leads to academia. The distal intercalated cells, however, function normally and so the academia is not as severe as in case of Distal RTA. The alpha-intercalated cells can acidify urine to a pH of 5.3 or less because they produce hydrogen ions. Proximal RTA is also associated with Fanconi Syndrome which is characterized by aminoaciduria, uricosuria, glucosuria, and tubular proteinuria.

  Combined distal and proximal RTA
Inherited carbonic anhydrase II deficit leads to combined distal and proximal RTA. This is accompanied by osteopetrosis, cerebral calcification, and renal tubular acidosis. Cases of combined distal and proximal RTA are very rare.

How is RTA understood?
The following steps are applied to analyze Renal Tubular Acidosis-
  Determining the anion gap in acidosis. The normal Anion Gap is 8-12 (4-6 mEq/L)
  Separating the renal from the extrarenal causes of normal anion gap acidosis
  Classifying the types of RTA
  If it is distal RTA, further tests will be necessary to support the diagnosis

How is RTA diagnosed?
Three types of tests can reveal if a person is affected by Renal Tubular Acidosis-
  Urine test
  Acid load test
  Physical examination

Treatment of RTA-
Doctors prescribe either or both of the following two types of therapies-

  Alkali therapy- The pH level of urine is restored and electrolytes are balanced
  Vitamin D supplements- If RTA leads to bone deformities or rickets, your doctor will prescribe vitamin supplements to strengthen your bones.

Timely diagnosis can prevent the effects of Renal tubular Acidosis from becoming compounded. With the right medication, a person can lead a healthy normal life.

What Should You Know About Renal Tubular Acidosis?

When you have pain in the stomach that is accompanied by nausea and vomiting, chances of you having chronic gastritis are high. This is an issue that specifically affects the stomach and is caused because the lining of the stomach gets inflamed and swollen and in some cases it may get damaged. The deterioration of the lining may be caused because of a bacterial infection and that would have to be treated with specialised medicines and treatment methods.During that time you may feel like there is something wrong with your digestive system and you may need to see a doctor for the constant pain that you have to go through as soon as you eat something.

Getting help
There may be times when you can no longer cope with the pain that may be occurring in your stomach. You may want to go to sleep or just sit still and do nothing; however, you cannot spend your entire life in that manner and you may have to consult an expert to get relief from the problem. One of the first steps in coping with chronic gastritis is to make sure that you make important lifestyle changes, such as eating healthy, choosing the right timings for eating, cutting down on alcohol and smoking and making sure that you choose a well-qualified and experienced doctor for getting the treatment.

Treatment
Apart from lifestyle changes, it is highly essential to follow a medication routine in order to beat the chronic gastritis completely. Doctors may suggest you take the medication according to the severity of the problem, but before that, you may be asked to go through a number of tests to confirm the problem. The tests may range from regular blood tests, stool tests, to endoscopy or even biopsy in some severe cases. After the testes are done, the doctors may be further sure about the the problem and that would be of great help in treating the issue with much more ease and expertise.

While it may be obvious to you that you suffer from chronic gastritis due to the constant pain in the stomach, it is also important to understand that the problem should not be taken lightly and that the right steps of the treatment should be taken in time before the problem gets worse.

Chronic Gastritis - How to Cope with it?

Celiac disease is a condition in which the small intestine becomes sensitive and reactive to gluten, leading to difficulty in digesting food. Gluten is a kind of a protein found in wheat or barley. In reality, if either of the partners is suffering from celiac disease then you are prone to fertility related issues.

Impact of Celiac disease

As compared to men, this disease is more common among women in general. Women suffering from the disease are generally more prone to infertility and other genealogical problems like preterm births and miscarriages. In the case of men, the disease causes the infertility problems including sperm abnormalities such as low count, abnormal shape, reduced function and such others. Additionally, men with the untreated celiac disease might also have reduced levels to testosterone.

Infertility and Celiac disease

Infertility is one of the lesser known effects of the celiac disease, which is relatively uncommon amongst people. The disease causes infertility by affecting the menstrual cycle among women either in a direct or indirect manner. Some of the infertility related problems caused due the disease are listed below.

Delayed occurrence of menstruation
Early menopause
Secondary amenorrhea (a medical condition associated with sudden cessation of menstruation for 6 months or more)
Hormonal disruptions and abnormal changes

Diagnosis

Celiac disease is usually diagnosed by its own set of underlying symptoms such as chronic fatigue syndrome, irritable bowel syndrome (IBS), iron-deficiency anemia, and such others. Additionally, the condition can be diagnosed if a person is having repeated miscarriages or inability to conceive for unidentified causes.

What can you do about it?

If you experience symptoms of Celiac disease, consult your doctor at the earliest and follow the treatments and preventative measures suggested. Additionally, you can also consult a dietician who will help you to move on to a low grain or no grain diet that would help you further to avoid the disease.

Does Celiac Disease Reduce Fertility?

The inflammation of your pancreas over a short period of time indicates acute pancreatitis, which is a serious health condition. You may experience symptoms such as severe abdomen pain all of a sudden, diarrhoea and feeling of being sick. Acute pancreatitis occurs when there are some problems with certain enzymes in the pancreas. This condition is often associated with gallstones and alcohol consumption.


Treatment
Acute pancreatitis can be cured in a hospital, where you will get monitored for signs of serious issues. In some cases, supportive things like oxygen and fluids are required. Here are the various ways by which the condition can be treated:


1. Fluids: The body may get dehydrated during acute pancreatitis. Fluids are provided via a tube connected to one of the veins of the patient. This is known as intravenous or IV fluid. These fluids may help in the prevention of a problem called hypovolemic shock, which occurs when the amount of blood in your body gets lowered due to a drop in fluids. 
2. Nutrition: Diet is usually not restricted for people with acute pancreatitis, but some patients are recommended not to consume solid food for some time. Attempting to digest solid food may cause a strain on the pancreas. You may need to avoid solid food for some days. You should use a feeding tube to get essential nutrients. This process is called enteral feeding and it may involve the insertion of a tube into your stomach via the nose. 
3. Oxygen: For ensuring sufficient oxygen supply to your vital organs, you will be supplied with oxygen through the tubes on your nose. The tube may be removed when your condition improves. In some cases, ventilation equipment may be required for assistance to breathe.
4. Painkillers: Acute pancreatitis causes severe abdominal pain and strong painkillers such as morphine may be given to the patient. These may make the patient feel drowsy. 


Treatment of underlying cause
After controlling the symptoms, the underlying cause must be treated. They are as follows:
1. Gallstone: When pancreatitis occurs because of a gallstone, you may require a process known as endoscopic retrograde cholangiopancreatography or ERCP. The gallbladder may have to be removed, if necessary. 


2. Alcohol consumption: After getting treated for acute pancreatitis and you have recovered from this condition, you should try to avoid alcohol completely. Alcohol may spoil your recovery and the condition might reoccur or the symptoms may reappear. For freedom from alcohol, you may try counselling, joining self-help groups such as Alcoholics Anonymous (AA) or take a medicine which reduces your craving for alcohol. 


It is recommended that you visit a doctor immediately after experiencing any slight or severe symptoms of acute pancreatitis. This will help in early diagnosis and the chances of the symptoms getting worse are prevented.

Acute Pancreatitis - Can it be Cured?

If you are finding certain symptoms like stomach pain, cramping, frequent diarrhoea, weight loss of your child or fever, then there are chances that he is suffering from crohn's disease. Crohn's disease is a bowel disease that causes swelling and inflammation along the digestive tract of your child. Mostly, it affects the end of the small intestine, but it can occur anywhere from the mouth to the anus.

Causes behind the disease
It is not common in children, but if your child is showing symptoms, then one of the following may be the reason:
1. Immunity system of the child,
2. Genetics, and
3. Environment.
The main cause behind such a disease can be any of the above. However, it has been found that if you have someone suffering from this disease in the family, then your child has more chances of getting affected by it.

Diagnosing crohn's disease
If you find the above-mentioned symptoms in your child, then it is better to take him or her to a doctor. Mostly, this disease is chronic in nature, meaning that it will continue even if it is treated. However, with proper treatment the symptoms can be reduced.
For diagnosing this disease the following tests may be done
1. Different lab tests that include a blood test for blood count and white blood cell count, and stool test to look for the bacteria that cause the inflammation and urine.
2. X-ray for detecting whether your child is suffering from crohn's disease and what is the exact position of it in the digestive tract.
3. If further required, they may do an endoscopy to find out the exact location and get more details.

Complications arising out of crohn's disease
If your child is suffering from this disease and is left without treatment for long, he or she may suffer from the following complications.
1. When the disease thickens, it may obstruct the intestinal walls by swelling of the intestine. Thus, the space from where the digestive matter passes becomes less and may lead to bowel obstruction.
2. Fissures may develop at the mucus membrane of the anus.
3. Fistulas or ulcers can occur as they tunnel through the affected area to the nearby tissues. All these are painful for your child to bear.
4. Your child cannot absorb the nutrients of the food like any other child and hence there are chances that they suffer from nutritional deficiencies.

With such problems that may not seem very huge in the beginning, your child may lose his appetite and forget about normal living. Thus, the moment you find any such symptoms, discuss them with your doctor.

What You Must Know About It if Your Child Suffers From Crohn's Disease

If you think fissure and fistula are the same, you are mistaken. While the term fissure refers to the tear of the skin, fistula refers to the abnormal tube-like passages or connections between organs. Fissures get cured with or without treatment in a few days to few weeks, and do not lead to complications. On the contrary, fistulas when left untreated may lead to complications.

So, read on further to know about the distinction, how to recognize the symptoms and avail treatment.

What is anal fissure?
An anal fissure can occur due to various reason, such as prolonged diarrhea, anal sex, vaginal childbirth, rectum cancer, etc. For majority of the cases, it is usually due to constant constipation or strained bowel movements, that tear down the muscles controlling the sphincters to the inner rectum or the anal canal.

What is anal fistula?
Anal fistulas are not tears but abnormal abscesses near the anus, filled with pus. In fistula, a tunnel is formed under the skin which connects these abscesses to the infected glands. Fistulas are usually the results of present or previous abscesses. If ignored or left untreated, one single fistula can lead to the development of a more complex fistula, where the single fistula tract ends up creating multiple openings.

Symptoms of anal fissure and anal fistula
Some of the common symptoms of an anal fissure are excruciating pain in the anal area every time the bowel movement occurs, constant itching or burning sensation in and around the anus, bloody stool and visible tears and cracks around the anus.

For anal fistula, some of the very common symptoms are a throbbing pain in the anus, which continues to increase, difficulty in sitting down for longer period, swelling and redness around the anus, accompanied by skin irritation, discharge of blood and pus, and at times fever.

Treatment options
To completely cure anal fissure and fistula, it is the various surgical options that are the most effective ones. However, when diagnosed in its earliest form, medications like antibiotics, analgesics, and antipyretics can often help. It is solely depending on the location, type, and size or severity of the fistula or fissure, the treatments may vary from person to person and so does the recovery time.

Though, these conditions cannot be cured with dietary changes or exercise, following a healthy diet can boost healthy bowel movement, reducing chances of constipation or diarrhea that results in fissures.
Prevention is always better than cure. Therefore, it is essential that you visit the nearest medical facilities once you notice any signs of fissure or fistula , to avail the right treatment and get relief from the symptoms quickly.


Don't Confuse Fissure With Fistula!

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