The gallbladder is a small organ in the abdomen that stores bile. Bile is necessary to digest fat that people take with food.

Unlike other cancers, Gallbladder cancer is not very common. It is also treatable in the early stages. However, in most cases, Gallbladder Cancer is detected in late stages. At these stages, the chance of a recovery is remote. What makes early diagnosis uncommon is the absence of specific signs or symptoms.

However, there are some signs that people need to look out for.

Signs of Gallbladder Cancer

Though there are not many specific symptoms, following signs can indicate a broad range of abnormalities, including some cancers.

Pain in the upper right quadrant of abdomen

Bloating

Fever

Weight loss

A feeling of nausea

Yellowing of the skin and eyes (sign of jaundice)

Many of these symptoms may involve other organs or indicate completely different ailments. This is why people need to see the symptoms in light of other concomitant symptoms and gauge the seriousness of the problems. If a person feels that a particular symptom is not solely a gastrointestinal problem, rush to the doctor immediately.

Causes of Gallbladder Cancer

Causes of Gallbladder Cancer are not entirely clear. However, in most cases, cancer spreads from the glandular cells of the gallbladder. These cells are found in the inner body of the gallbladder. This is also known as Adenocarcinoma. Slowly, it spreads from the inner body to other organs of the body.

Risk Factors

Though the reasons for Gallbladder Cancer are not yet known, certainly there are some factors that exacerbate the risk:

Gender
More women than men suffer from Gallbladder Cancer.

Age
The risk of Gallbladder Cancer increases with age.

History of Gallbladder Stone
It has been observed that most of the Gallbladder Cancer patients have had a history of gallbladder stones. However, this does not mean that Gallbladder Cancer is common in people with a history of gallbladder stone.

Chronic gallbladder infection, gallbladder polyps, etc. can increase the risk of Gallbladder Cancer.

Stages of Gallbladder Cancer

Gallbladder Cancer is categorized into different stages in accordance with its spread:

Stage I
If cancer is confined within the glandular cells of gallbladder, it is put in this stage.

Stage II
If cancer has grown out of the inner layers and has invaded the outer layer of the organ, it is put in the second stage.

Stage III
If cancer has grown to such an extent as to invade nearby organs like liver, stomach, small intestine, etc., Gallbladder Cancer is put in this stage.

Stage IV
The last stage of Gallbladder Cancer is characterized by large tumors, taking into their fold multiple organs in the vicinity. Tumors may also spread to distant parts of the body.

Treatments of the Gallbladder Cancer

The treatments depend a lot on the stage of cancer and overall health. The primary goal is to remove the diseased gallbladder. It may also be possible to resect part of the liver and bile duct along with the gallbladder.

However, if that is not possible, doctors may need to resort to other therapies to prevent the disease from spreading. This may involve Radiation Therapy or Chemotherapy or a combination of both.

There are many treatments available for Gallbladder Cancer depending upon the severity of the cancer. This is why it is important to consult a doctor before opting for any treatment.

Gallbladder Cancer - Signs, Causes & Treatment Of It!

Renal Tubular Acidosis is a medical condition. When the kidney is unable to acidify urine, it leads to the accumulation of acid in the body. Usually, when blood is filtered by the kidney, it passes through the tubules of the nephrons (the functional unit of the kidney).

Before it flows into the bladder from the kidney, the urine undergoes an exchange of salts, acids and other solutes. Renal tubular acidosis results in the formation of excessive amounts of acid because the kidneys cannot drain them. This may happen because the kidneys cannot reabsorb the alkaline bicarbonate ions from the urine in the early segment of the nephron or because of inadequate production of acidic hydrogen ions in the latter half of the nephron.

Renal Tubular Acidosis is simply associated with abnormal urinary acidification. Other functions of the kidneys remain unimpaired.
There are several different types of renal tubular acidosis-

  Distal Renal Tubular Acidosis (RTA)
This is the most fundamental form of RTA. It is characterized when the hydrogen ions are not secreted into the lumen of the nephron by the alpha-intercalated cells of the medullary collective duct of the distal nephron. When this happens the pH of urine cannot be brought down below 5.3. Renal excretion is inhibited and hydrogen ions are not eliminated which leads to academia. At the same time, Potassium ions cannot be absorbed by the cell which leads to hypokalemia. The end result is protein retention and potassium excretion. Distal RTA can lead to the urinary stone formation, calcium deposits in the kidney, rickets and osteomalacia and Sjogren s syndrome.

  Proximal RTA
When proximal tubular cells reabsorb 85% of filtered bicarbonates and 60% of filtered sodium from the urine, then this again leads to academia. The distal intercalated cells, however, function normally and so the academia is not as severe as in case of Distal RTA. The alpha-intercalated cells can acidify urine to a pH of 5.3 or less because they produce hydrogen ions. Proximal RTA is also associated with Fanconi Syndrome which is characterized by aminoaciduria, uricosuria, glucosuria, and tubular proteinuria.

  Combined distal and proximal RTA
Inherited carbonic anhydrase II deficit leads to combined distal and proximal RTA. This is accompanied by osteopetrosis, cerebral calcification, and renal tubular acidosis. Cases of combined distal and proximal RTA are very rare.

How is RTA understood?
The following steps are applied to analyze Renal Tubular Acidosis-
  Determining the anion gap in acidosis. The normal Anion Gap is 8-12 (4-6 mEq/L)
  Separating the renal from the extrarenal causes of normal anion gap acidosis
  Classifying the types of RTA
  If it is distal RTA, further tests will be necessary to support the diagnosis

How is RTA diagnosed?
Three types of tests can reveal if a person is affected by Renal Tubular Acidosis-
  Urine test
  Acid load test
  Physical examination

Treatment of RTA-
Doctors prescribe either or both of the following two types of therapies-

  Alkali therapy- The pH level of urine is restored and electrolytes are balanced
  Vitamin D supplements- If RTA leads to bone deformities or rickets, your doctor will prescribe vitamin supplements to strengthen your bones.

Timely diagnosis can prevent the effects of Renal tubular Acidosis from becoming compounded. With the right medication, a person can lead a healthy normal life.

What Should You Know About Renal Tubular Acidosis?

Irritable bowel syndrome (IBS) or spastic colon is a rather common intestinal tract disease which is characterized by sharp pain in the stomach, stomach gas, diarrhea or constipation. It is a chronic condition whose exact cause, although unknown, is sometimes attributed to the dysfunctional production of the neurotransmitter, dopamine.

There is no particular treatment for IBS. However, the symptoms can be brought under control through various methods. The symptoms of IBS can be controlled by making lifestyle changes such as incorporating certain modifications to your diet and reducing or managing stress levels. For severe symptoms, you may require medications.

Patients may also consider homeopathic treatment for a rather wholesome effect and lesser side effects. The purpose of homeopathic treatment is to stimulate the body s inner self-balancing mechanisms. In order to achieve this, this person must be provided with the right solution at the right time. Since homeopathy aims at treating the root cause of the problem, the treatment is stretched over a longer period of time. Additionally, homeopathy functions by stimulating the natural healing capabilities of the body. Some of the common homeopathic medications that can be used to treat IBS are listed below:

Pulsatilla: Prepared from a medicinal plant known as wind flower, Pulsatilla is effective in the cure of IBS with its remedying effect on the gastrointestinal tract.
Nux Vomica: This too is derived from a plant and has a positive effect on the digestive and nervous system, thereby being effective in the treatment of IBS.
Sulphur: It is one of the most common choices among homeopathic practitioners for IBS. Sulphur affects the digestive tract and is helpful in the treatment of intestinal gas and constipation. It is usually prescribed for individuals who are rather thin and physically weak.
Lycopodium Clavatum: This is mainly prescribed for people with diarrhea and stomach gas. This drug acts specifically on the gastrointestinal tract
Asafoetida: This drug is prescribed when there is a fairly common constriction in the bowel muscles.

Irritable Bowel Syndrome - 5 Homeopathic Remedies For It

Celiac disease is an autoimmune disease caused due to intolerance to the protein called gluten found in common foods like wheat, barley, and rye. The exact reason for the disease is not known, but gluten attacks the small finger-like projections in the intestine called the villi, which help absorb nutrients during the digestion, leading to malnourishment.

Onset of the disease is usually once the child has started on solid foods and can include diarrhea, abdominal discomfort, underweight, skin rashes, anemia, mouth sores, etc.
Diagnosis usually happens with a detailed discussion and checking the level of antibodies against gluten in the blood. In rare cases, an intestinal biopsy may also be required. Once confirmed, the following are ways to manage celiac disease-

Dietary changes: avoiding gluten-containing foods is the first step to treating celiac disease. These are common food substances like wheat and barley. In some cases, the entire family may choose to or need to take this diet, just to provide moral support to the child.
1. Breads, cakes (made from wheat)
2. Creamed or breaded vegetables
3. Processed meats
4. Dry roasted nuts (as agents used in processing could have wheat)
5. Fried chicken
6. Pastas
7. French fries (that are coated in flour)
8. Spreads, soft cheeses, and dips
9. Salad dressings
10. Gravies and sauces (including some tomato and meat sauces)
11. Soup mixes and canned soups
12. Crab or other seafood
13. Malt or malt-flavored drinks (usually made from barley)
14. Modified food starch (modified corn starch is ok; modified wheat starch is not)
15. Nondairy creamer
16. Soy sauce and soy sauce solids (may be fermented with wheat)
17. Wheat-free products (may contain barley or rye flour)
18. Yogurts containing wheat starch
Read the labels of foods to ensure they are free of gluten. Organic/natural food stores and health food stores contain wide range of gluten-free products that can be used with minimal effect on the child's food habits.

Eating out: just because the child has celiac disease, eating out is not ruled out. Carefully choosing what to eat is suggested. Also, letting the chef know is a good idea, as most chefs will prepare something safer for the child.

Cross-contamination: avoid cross-contamination: in schools or in cases where the child could potentially eat from other children's boxes, make sure the child is well informed and ensure he does not eat from other kids' lunch boxes. It is also a good idea to keep the class teacher and a couple of his close friends informed of the child's condition.

Most children are easy to educate and adapt well to the changes required, knowing very well that it is for their own good.

Tips to Deal With Celiac Disease in Children

Colitis is characterized by an inflammation of the large intestine (colon). It is generally caused due to reduced blood supply, autoimmune reactions (wherein the immune system erroneously starts attacking the body s healthy tissues) and infections in the large intestine.

Symptoms of colitis
1. Presence of blood traces in the stool.
2. Acute colitis can itself be a symptom of hemorrhoids (inflamed and swollen veins in the anus or the rectum)
3. Tenesmus (constant urge to empty the bowels) is also quite common
4. Occurrence of abdominal pain in regular intervals, thus resulting in diarrhea
5. Constant abdominal pain
6. Fever and sudden chills throughout the day

Types of colitis
1. Inflammatory bowel disease: This condition is characterized by inflammation of the intestines or all the parts of one s digestive tract
2. Microscopic colitis: This involves inflammation of the large intestine (colon), resulting in a cramping sensation that can be painful
3. Chemical colitis: This condition is caused due to prolonged exposure to certain harsh chemicals which results in intestinal swelling and inflammation
4. Ischemic colitis: The most common form of colitis, this occurs mainly due to an insufficient blood supply to the large intestine
5. Infectious colitis: Caused due to certain bacterial or parasitic infections

Treatment for colitis
1. Medications such as acetaminophen and ibuprofen can be recommended to ease the pain
2. The drug  Loperamide  can control the diarrhea. However, this should not be consumed if there is presence of blood in the stool
3. Colitis reduces your appetite. Thus, it is important to maintain a healthy diet in this regard. Avoid consuming dairy products or high fiber foods because they further inflame the large intestine.
4. Colectomy (surgically removing a part of the whole of the colon) is recommended in the most severe of cases.

Colitis - 5 Common Types!

A Gastroenterologist is a physician with dedicated training and unique experience in the management of diseases of the gastrointestinal tract and liver. If you are planning to visit one, you most likely have a problem in one or many organs like esophagus, stomach, small intestine, colon and rectum, pancreas, gallbladder, bile ducts and liver. 

Visit your doctor to understand the severity of your condition and the course of treatment, as it is obvious that during this time you must be suffering from anxiety and you may not ask the questions arising in your mind. That is why you need to prepare in advance for your first visit with a gastroenterologist. Being an active partner in the doctor patient relationship is bound to have its benefits. Here are some handy tips:

1. Come mentally prepared: Don't let the anxiety get to you. If you need some extra help calming down, try yoga or meditation. You can simply go out on a walk alone to help you focus your thoughts. This is just like any other doctor visit. The good part is that you are taking the first step in easing your discomfort and starting treatment, so go with a positive mind.

2. Maintain a diary of symptoms: It is likely that you are experiencing discomfort from past few days or weeks before you finally realize the need to seek out a specialist. Try to remember as much as possible about the symptoms you experienced in a chronological order. Write down any over the counter medicines you've tried or anything unusual that you may have consumed in the past week. 

3. Take stock of your medical history: It is likely that your doctor may want to know about any historic conditions you've suffered that may or may not relate to your present condition. Many ask you to fill out forms during your first time patient registration which includes many minor details about your medical past. List down any allergies, especially food allergies you have. 

4. Take stock of your recent medical tests: Bring your latest blood tests and imaging tests (X-rays, ultrasounds, MRIs, and CT scans) with you for the doctor's visit. If you have a pre-existing condition like diabetes, thyroid or you suffer from other chronic conditions like increased uric acid, carry your most recent medical reports with you. 

5. Make a list of questions for the doctor: In most cases, the first visit is a crucial factor in determining whether you want to continue the course of treatment with a particular doctor. This comes out of your ability to trust the doctor, his knowledge and diagnosis and an overall comfort level that comes with how well he handles your questions. Start by making a list of questions you want to ask about your specific condition and course of treatment and see if you get satisfactory answers. 

6. Brace yourself: If you want to suggest a treatment option, make sure you read up all about it before you tell the doctor.

6 Tips For Your First Visit With A Gastroenterologist

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