Thalassemia is a genetic (which is passed from parents to children through genes) blood disorder. People with Thalassemia disease are not able to make enough hemoglobin, which causes severe anemia. Hemoglobin is found in red blood cells and carries oxygen to all parts of the body. When there is not enough hemoglobin in the red blood cells, oxygen cannot get to all parts of the body. Organs then become starved for oxygen and are unable to function properly.

Symptoms

The symptoms depend on the type of thalassemia:

Thalassemia Minor: Thalassemia minor usually doesn t cause any symptoms. If it does, it causes minor anemia.
Beta-thalassemia: Beta-thalassemia comes in two serious types, which are thalassemia major, or Cooley s anemia, and thalassemia intermedia. The symptoms of thalassemia major generally appear before a child s second birthday. The severe anemia related to this condition can be life-threatening. Other signs and symptoms include:
fussiness
paleness
frequent infections
a poor appetite
failure to thrive
jaundice, which is a yellowing of the skin or the whites of the eyes
enlarged organs
This form of thalassemia is usually so severe that it requires regular blood transfusions.

Alpha-thalassemia: Alpha-thalassemia also has two serious types, which are hemoglobin H disease and hydrops fetalis. Hemoglobin H disease can cause bone issues. The cheeks, forehead, and jaw may all overgrow. Hemoglobin H disease can cause:
jaundice, which is a yellowing of the skin or the whites of the eyes
an extremely enlarged spleen
malnourishment
Hydrops fetalis is an extremely severe form of thalassemia. It occurs before birth. Most individuals with this condition are either stillborn or die shortly after being born.

Thalassemia - Symptoms Based on Types of Thalassemia 

Anemia refers to a condition wherein the body possesses fewer red blood cells than what it contains under normal circumstances. Oxygen gets carried by the red blood cells to tissues and organs all over the body, thereby enabling them to use the necessary energy from food. A person suffering from anemia, will have his red blood cells carrying less amount of oxygen to organs like heart and brain, thus interrupt smooth functioning of the organs. Kidney disease leads to the problem of anemia. In fact, it is a very common side effect of kidney disease, wherein the body fails to produce the required amount of red blood cells.

What results in anemia?
A person can suffer from the problem of Anemia, when sufficient amount of red blood cells are not there in the body. Oxygen is carried through a person s bloodstream by the Red blood cells, providing him energy and also ensure that the bones, muscles and organs function properly. Anemia can make a person feel weak and very tired as he or she is unable to receive the required amount of energy.

How can chronic kidney disease lead to anemia?
Anemia is common among people, who suffer from chronic kidney disease, though the problem can occur to anyone. People suffering from chronic kidney disease may have anemia during the early stages of their kidney disease and as the kidney problem gets worse, so does anemia. Improper functioning of kidneys generally link towards the problem of anemia. People, who suffer from complete loss of kidney function, tend to develop the problem of anemia. Kidney failure leads to a person, requiring dialysis or kidney transplant, for ensuring longevity.

Anemia becomes even more common in chronic kidney disease, if a person:

Has high diabetes.
Is suffering from heart problems.
Has a high level of blood pressure.
Some of the other causes of anemia in people, suffering from kidney disease include loss of blood from hemodialysis and lower levels of some of the nutrients like iron, folic acid and vitamin B12, found in food.
These three nutrients are essential for the red blood cells to make haemoglobin, which is the main carrier of protein through oxygen in red blood cells.

Signs and symptoms of anemia with chronic kidney disease
The signs and symptoms of anemia in someone, suffering from chronic kidney disease are:

He might have terrible weakness.
A person might suffer from headaches on a frequent basis.
There would be problems with regard to concentration.
The color of the skin would become pale.
Treatment
A doctor would try and increase the levels of iron in a person s body, as the first step of treatment. Iron pills would help in improving the levels of iron and haemoglobin. Red Blood Cell transfusion is another way to treat this problem. Transfusion would be done inside the patient s vein by raising the level of the patient s blood consisting of red blood cells, thereby also increasing the amount of oxygen. Vitamin B12 and Folic Acid supplements are also suggested by healthcare providers, to help treat anemia.

Anemia - How Chronic Kidney Disease Can Lead To It?

Did you know that Thalassemia is a common blood disorder in India, that?s passed through families (just the way it was passed to Abhishek Bachchan because megastar Amitabh Bachchan is a carrier). It is characterized by excessive destruction of red blood cells or genetic mutation, leading to anaemia. Today is World Thalassemia Day, lets understand about the disease.

Thalassemia can be classified into alpha and beta, depending on the globin genes that are affected.

1. Thalassemia Minor - Usually doesn?t have any symptoms, except for minor anaemia.

2. Beta Thalassemia - Has two serious types.

2.A) Thalassemia Major: This type usually happens before a child?s second birthday and requires regular blood transfusions. The condition is life-threatening. Symptoms include anaemia, fussiness, frequent infections, paleness of the skin, poor appetite, enlarged organs and jaundice.

2.B) Thalassemia Intermedia: It is a less severe form and doesn?t require blood transfusions. The symptoms include anemia, jaundice, extremely large spleen and malnourishment.

3. Alpha Thalassemia: Only in rare cases this severe form of Thalassemia may be present. Known as Hydrops Fetalis, this condition usually occurs before birth and children are either stillborn or die soon afterwards.

How to live with Thalassemia:

Take steps to be as healthy as possible. Follow a balanced diet eating plan as per the recommendation of your doctor. Take iron supplement only if prescribed. It is recommended that patients get themselves vaccinated whenever needed, especially if their spleen has been removed. Meanwhile, always be on a lookout for the signs of infections (such as fever) and lower your risk of infections. Thalassemia can spark fear, anxiety, depression and stress. That?s why, doctors recommend that patients receive adequate emotional support.

Treatment:

The treatments depend on the kind of Thalassemia an individual has. Usually, treatment procedures include blood transfusions, bone marrow transplants, removal of spleen or gallbladder specific medications and supplements.

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Read Dr. Jatin Soni's Health Tip on The Occasion of World Thalassemia Day

Your body goes through drastic changes when you are pregnant. Your body makes more blood during pregnancy; for instance, prior to pregnancy, your body made approximately 5 litres of blood, but now it produces 7 to 8 litres of it.
Producing excess red blood cells requires haemoglobin, which in turn requires plenty of folate, iron and vitamin B12. If there is a deficiency in any of these requirements, you might develop anaemia.
Anaemia is a condition, which is characterized by a lack of red blood cells in the body. The risks of becoming anaemic during pregnancy include:
1. Being extremely fatigued
2. Miscarriages, premature birth, or low birth-weight
3. The baby can inherit anaemia from the mother
4. The child can have certain developmental delays
5. Postpartum depression (post-childbirth depression)

How it can be prevented?
To prevent such risks, it is important to implement the proper diet. Here are some dietary tips to prevent anaemia during pregnancy: 
1. Consume iron-rich foods: Foods that provide you with the best source of iron are 
i. Poultry and eggs
ii. Dark green and leafy vegetables (for example: spinach, broccoli and kale)
iii. Seeds and nuts
iv. Beans and lentils
v. Tofu
vi. Beetroot
vii. Ripe bananas

2. Don't forget the supplements: Foods are great sources of the nutrients you require, but they may be lacking at times. Ask your doctor for supplements like vitamin, folic acid and iron supplements mostly. Consuming supplements before pregnancy can go a long way in preventing anaemia.

3. Folic acid is important: Folic acid is very important for pregnant women. You must consume 400 milligrams of it to prevent anaemia and birth defects in babies. Foods that are rich in folic acid include:
i. Beans
ii. Muesli
iii. Broccoli
iv. Brussel sprouts
v. Asparagus

4. Vitamins are crucial: Vitamin C helps in iron absorption which boosts haemoglobin production. Some foods rich in vitamin C include
i. Citrus fruits
ii. Strawberries
iii. Kiwis
iv. Tomatoes
v. Bell peppers

5. Be vigilant while cooking: Sometimes while cooking foods, the wrong method can strip them of their iron content. So be careful not to fry, boil or stew such foods too much. Certain foods are best consumed raw; read the labels properly if in doubt.

6. Abstain from certain habits: Alcohol, tea, cigarette and coffee hinder iron absorption. So stop consuming them if you are trying to conceive or have conceived.

Dietary Tips to Prevent Anaemia in Pregnant Women

Anemia, as known to many, is a medical condition triggered by low hemoglobin levels. More than often, iron deficiency acts as a catalyst giving rise to anemia. While fatigue, headache, palpitations, skin pallor, and dizziness are characteristic of anemia, many people also suffer from hair loss. Here too, the iron deficiency acts as contributing factor interfering with the healthy growth cycle of the hair. In some cases, the hair loss may mimic the male and female pattern baldness as observed in the case of Alopecia. While anemia and the related hair loss can affect anyone irrespective of their age and sex, women of reproductive age, as well as teenagers, are more susceptible to this. In this article, we will discuss the anemia and iron deficiency induced hair loss in brief and the preventive measures to deal with the situation.

Anemia-related Hair Loss
In anemia, there is a significant fall in the hemoglobin level. Hemoglobin acts as an oxygen carrier to different body cells and tissues, including those of the hair follicles to ensure healthy cell growth and repairment. Low hemoglobin levels result in inadequate oxygen supply, one of the prime factors responsible for hair loss.

Ferritin, a storage protein (cellular protein) for iron contributes significantly towards a healthy growth cycle of the hair (stimulates the anagen or the growth phase). In the case of anemia, to meet the iron requirements of the vital organs such as the heart, the body starts utilizing the ferritin stored in hair bulb and other non-essential tissues. This dip in the ferritin level affects the hair growth. A ferritin blood test often helps in the diagnosis of iron deficiency and anemia.

Preventive measures to deal with anemia related hair loss
With the iron deficiency and the associated symptoms being taken care of, the anemia triggered hair loss can be controlled and reversed. In addition to the medications and treatment, one also needs to take care of their general health and lead a healthy lifestyle.

Never go for self-medication. It will only worsen the situation. Two individuals can have the same medical problem but triggered by different factors. Always consult a doctor before trying any medicines.
Follow a healthy diet: People dealing with anemia and iron deficiency should enrich their diet with foods rich in iron such as lean meat, liver, spinach, beetroot, nuts and dry fruits (walnuts, almonds), prunes, parsley, broccoli (the florets), to name a few. Foods rich in vitamin C, almonds, are known to promote hair growth.
Avoid drinking tea between meals as this unhealthy practice is known to interfere with the absorption of iron.
Maintain a healthy hair care routine
Oil massage your hair at least twice a week.
Be gentle while combing the hair.
Try and use a mild shampoo (or as the doctor recommended).
Avoid excessive use of hair styling products and chemicals.

Anaemia And Hair Loss - What Should You Do?

Anemia (or anaemia) is a medical condition which generally occurs in a human body because of the lack of required healthy red blood cells (RBCs) or hemoglobin in the blood. Diagnosis of anemia is done through a blood test, a man is anemic when his hemoglobin level is less than 13.5 gram/100 ml and a woman is anemic when her hemoglobin level is less than 12.0 gram/100 ml.

Risk factors: People suffering from long-term or chronic diseases such as cancer are more susceptible of developing anemia. Hemoglobin is the salient constituent of red blood cells and is an iron rich protein. It provides the red color to the blood and binds oxygen. Red blood cells carry this oxygen to all the vital tissues and organs of the body. Due to lack of appropriate amount of red blood cells, the amount of blood required in a body to function normally is also low. One of the most prominent causes of occurrence of anemia is the deficiency of required amount of nutritional iron, vitamin B-12, and folate in the body. This iron is needed for the formation of hemoglobin. Apart from these causes, the other causes of anemia comprise of the following:

Loss of blood
Insufficient production of red blood cells (inadequate intake of iron, vitamin B-12)
Fast rate of destruction of red blood cells (disorders of liver and hemorrhage)
Diagnosis: It is relatively easy to detect an anemic person. The symptoms of anemia include pale appearance, complaint of cold, giddiness, unsteadiness, laziness, particularly when the person is in action or is standing up. Sometimes people suffering from anemia crave for eating clay, ice, or even dirt. Also, there are complains of exhaustion along with issues of constipation and concentration. Other indications of anemia are brittle nails, gasps for breath even in mild activities, and pain in the chest. Since the level of oxygen in the blood is low, there could be even scope of a heart attack.

A person suffering from anemia is usually diagnosed on the basis of a complete blood count. The blood test brings out if serum folate levels are quite low. In case the anemia is severe, sometimes doctors take the help of erythropoietin injections so as to foster the production of red blood cells in the bone marrow. In case there is bleeding or if the level of hemoglobin is low, it might become essential to carry out blood transfusion.

Treatment: Anemia is straightforward to diagnose and treat, but at the same time could prove to be deadly if it is left undiagnosed. Proper heed should be paid to the intake of adequate and required food which is rich in vitamins and minerals, dietary iron, folic acid, including other vitamins and minerals.

Anemia- How Does It Affect a Person's Health?

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