Hypothyroidism is a condition in which the thyroid gland is not producing the thyroid hormones adequately. This is a fairly common condition.

What is thyroid gland?

The thyroid gland is a small butterfly-shaped gland located just below Adam s apple. It encircles the windpipe or the trachea. It is about 4 cms in height and weighs about 18 gms. This gland is responsible for the secretion of thyroid hormones. Hormones are chemicals produced by special glands like thyroid, adrenals, ovaries etc. They act as messengers and are carried by the blood to the various target organs.

What are the hormones produced by thyroid gland and what do they do?

The thyroid hormones are of two types   T3 (Tri iodo thyronine) and T4 (Thyroxine). These hormones are mainly responsible for the body s metabolism - a process in which food is converted into energy in the cells. They influence growth and development and regulate various bodily functions which are mentioned below:

Heartbeat
Body temperature
Breathing
Body weight
Metabolism of fat
Menstrual cycles in females
Functioning of Nervous system
Digestion
Burning calories etc.
What is Hypothyroidism?

Inadequate production of hormones by the thyroid gland is termed as hypothyroidism. This is also called Underactive thyroid state. Hypothyroidism can make the body s development to slow down and reduces metabolism rates.

What are the causes of Hypothyroidism?

Hypothyroidism can be caused by a number of factors:

Hashimoto's thyroiditis: This is the commonest cause. This is an autoimmune disorder (normally body s defence system fight against external infections. In autoimmune disorder the defence system attacks the healthy cells of the body by mistake). In Hashimoto s thyroiditis the immune system/defence system produces antibodies that attack the thyroid gland and destroy it.
Iodine deficiency in diet. For the production of thyroid hormones iodine is very important. The body does not produce iodine normally, so it needs to be supplemented from outside. Iodine is mainly present in the food we eat. It is mainly present in shellfish, salt-water fish, eggs, dairy products. If a person does not eat iodine rich foods, he may end up with iodine deficiency leading to hypothyroidism. Currently, this causative factor is on the decline due to government initiative of table salt with iodine.
Surgery: Surgery to remove thyroid gland (for e.g. thyroid cancer treatment, overactive thyroid etc.)
Radiation to the neck (to treat cancer in the neck area): The thyroid gland cells are damaged due to the radiation.
Treatment with radioactive iodine: This treatment is used for managing hyperthyroidism/overactive thyroid, where the thyroid gland produces excessive thyroid hormones. One of the treatment modalities is by radioactive iodine. Sometimes this radiotherapy destroys normal functioning cells which lead to hypothyroidism.
Certain medicines: Certain medicines used to treat heart conditions, cancer, psychiatric conditions etc.   for e.g. amiodarone, lithium, interleukin-2, interferon-alpha.
Pregnancy: Pregnancy (the reason is unclear but it has been noticed that the thyroid may get inflamed after delivery   this is called Postpartum thyroiditis.
Damage to the pituitary gland: Pituitary gland is a gland which is present in the brain. It produces a hormone called TSH (Thyroxine-Stimulating hormone).The TSH tells the thyroid gland how much thyroid hormone it should make. If the levels of thyroid hormone in the blood are low, then the TSH will stimulate the thyroid gland to produce more Thyroid hormone.
Hypothalamus disorders: This is an organ in the brain. This produces a hormone called TRH (Thyrotropin Releasing Hormone) which acts on the Pituitary gland to secrete TSH. So any disorder of Pituitary gland will indirectly effect the production and secretion of Thyroid hormones. These are very rare disorders.
Congenital thyroid defects: Some babies are born with thyroid problems. This is due to the thyroid not being developed normally during pregnancy. Sometimes the thyroid gland does not function normal. This can be identified by screening for thyroid disorders in the first week after delivery. This is usually by a blood test using a small drop of blood from the baby s heel.
What are the different types of hypothyroidism?

One classification is based on whether the defect is with the thyroid gland or not:

Primary hypothyroidism: The problem is in the thyroid gland itself and thus there is reduced production /secretion of thyroid hormones.
Secondary hypothyroidism: Here the problem is with the Pituitary gland or the Hypothalamus. This results in abnormal production of TSH or TRH, which indirectly leads to less production and secretion of thyroid hormones.
Another classification is based on the symptoms and levels of the thyroid hormones and TSH:

Overt hypothyroidism: Here the patient is having the symptoms. Further the T3/T4 are low and TSH is high
Subclinical hypothyroidism: Here patient may or may not have symptoms. The T3/T4 levels are normal but TSH is high. In this situation the patient is at an increased risk of developing overt hypothyroidism in the future especially if he has Thyroid peroxidase antibodies on testing.
Who are at risk of developing Hypothyroidism?

Women have a higher risk of suffering from hypothyroidism than men.
Older people are at increased risk.
People suffering from other autoimmune diseases like Coeliac disease, Type-1 Diabetes Mellitus, Vitiligo, Pernicious anemia, Multiple sclerosis, Rheumatoid arthritis, Addison s disease etc.
People with psychiatric conditions such as bipolar disorder
People with Chromosomal abnormalities like Down syndrome, Turners syndrome also have a high risk of suffering from hypothyroidism.
What are the symptoms of hypothyroidism?

Symptoms vary from person to person. They may also mimic other conditions and hence be difficult to diagnose. Symptoms may also develop very slowly over a span of moths-years. Some of the characteristic symptoms of this disease are:

Depression
Constipation
Hair loss
Dry hair
Dryness of the skin
Tiredness
Body pains
Fluid retention in the body
Irregular menstrual cycle
Increased sensitivity to cold
Reduced heart rate
Increase in size of the thyroid gland   called Goitre. This is due to constant stimulation of the thyroid gland by TSH.
Weight gain
Carpal tunnel syndrome
Hoarse voice
Infertility
Loss of libido/sex drive
Confusion or memory problems especially in the elderly
What are the symptoms to look for in a baby if you suspect hypothyroidism?

Infants suffering from congenital hypothyroidism may show no symptoms or exhibit signs of excessive drowsiness, cold hands, cold feet, constipation, hoarse cry, poor growth or absent growth, poor appetite, bloating of abdomen, puffiness of face, swollen tongue, persistent jaundice.

How to diagnose hypothyroidism?

Blood tests:

TSH: This hormone is made in the pituitary gland and it stimulates the thyroid gland to produce thyroxine. If the thyroxine levels are low in the blood, the pituitary gland produces and secretes more TSH into the blood to act on the thyroid gland to produce more thyroxine. A raised TSH level indicates hypothyroidism. Other tests are not usually necessary unless a rare cause of hypothyroidism.
T4: A low level of thyroxine indicates hypothyroidism.
T3: these levels are generally not needed to diagnose hypothyroidism
Anti-Thyroid peroxidase antibodies (anti-TPO antibodies) or Anti- thyroglobulin antibodies are present in 90-95% of patient with autoimmune thyroiditis.
Other blood tests include Creatinine Kinase, Serum Lipids, Complete blood picture etc.
Ultrasound of the neck is done if the patient presents with a thyroid swelling.
What is the treatment of hypothyroidism?

Overt hypothyroidism is treated by synthetic Thyroxin hormone which should be taken every day on an empty stomach at least 30   45 minutes before breakfast. The treatment is continued for the rest of the patient s life. Regular thyroid function tests are done once every 8 weeks-12 weeks to adjust the dose of the thyroxine in the initial period of diagnosis. Once the thyroxine dose is stabilised, the tests can be done even once a year. This treatment is quite effective.

Sub-clinical hypothyroidism is only treated if the patient is a woman and is contemplating pregnancy, in patients with symptoms or if the TSH is quite high.

What are the side-effects of thyroxine medication?

There are few side effects if any. Most people tolerate these medications quite well. An important consideration before starting medication is to check if the patient has chest pain/angina. These people are started on the least available dose. If these patients are started on a higher dose they notice a worsening of their angina pains.

Side effects mainly occur if the thyroxine dose is high which leads to hyperthyroidism. The symptoms of this could be palpitations 9increased heart beat), weight loss, profuse sweating, anxiety, irritability etc.

There are some tablets which increase with thyroxine tablets. These include carbamazepine, iron supplements, calcium supplements, rifampicin, phenytoin, warfarin etc.

What are the complications of hypothyroidism?

If untreated hypothyroidism can lead to:

heart problems like heart attack due to increased levels of bad cholesterol like LDL, or heart failure due to fluid retention
obesity
infertility
joint pains
depression
A pregnant woman with hypothyroidism is at increased risk of giving birth to a baby with congenital hypothyroidism, also known as cretinism. Further, the woman may have pregnancy related complications like pre-eclampsia, premature delivery, low birth weight baby, anemia, post-partum haemorrhage (bleeding after delivery) etc.
Myxoedema is another complication where the patient has extremely low levels of thyroid hormone. The body temperature drops drastically making the person lose consciousness or go into a coma.
References:

2013 ETA Guideline: Management of Subclinical Hypothyroidism; European Thyroid Association (Nov 2013)
Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee; British Thyroid Association (2015)
The diagnosis and management of primary hypothyroidism; Royal College of Physicians and others (June 2011)
Suh S, Kim DK; Subclinical Hypothyroidism and Cardiovascular Disease. Endocrinology Metabolism (Seoul). 2015 Aug 4.
UK Guidelines for the Use of Thyroid Function Tests; British Thyroid Association (2006)
Gaitonde DY, Rowley KD, Sweeney LB; Hypothyroidism: an update. American Family Physician. 2012 Aug 1 86(3):244-51.
Bindra A, Braunstein GD; Thyroiditis. American Family Physician. 2006 May 15 73(10):1769-76.
Wilson GR, Curry RW Jr; Subclinical thyroid disease. American Family Physician. 2005 Oct 15 72(8):1517-24.
British National Formulary; NICE Evidence Services (UK access only)
Baumgartner C, Blum MR, Rodondi N; Subclinical hypothyroidism: summary of evidence in 2014. Swiss Medical Weekly. 2014 Dec 23 144:w14058. doi: 10.4414/smw.2014.14058. eCollection 2014.

Know Everything About Hypothyroidism

Get rid of suntan: 6 effective home remedies

Sun tan is a common issue this time of the year. A severe sun tan not only robs the skin of its natural glow, but also makes it itchy, lifeless and unhealthy. Here are six simple remedies you can easily follow to remove your tan and get your glowing skin back:

1. Turmeric face pack
Turmeric is commonly known as the best home medication and it indeed has several beneficial effects. Mix a spoonful of turmeric in a bowl of milk and apply the mixture to your face. Keep for 15 minutes and remove.

2. Lemon juice
Cut a lemon and rub the sliced portion on the tanned areas of the body. Wash off after keeping for 5-10 minutes and follow this procedure on a daily basis.

3. Honey and papaya face pack
Honey helps keep the skin soft and supple whereas papaya contains enzymes that enable whitening of skin and effective exfoliation. Blend the mixture of papaya and honey and apply on your face for at least half an hour to experience effective tan removal.

4. Sandalwood paste
Sandalwood has the capability to soothe the skin and rejuvenate it to return its natural glow. Sandalwood paste should be applied right before bedtime on a daily basis to help reduce the effect of sun tan.

5. Yogurt
Yogurt is the best natural anti-tanning agent. Applying it on the tanned areas of your skin not only cools it off but also helps retain the natural complexion of the skin.

6. Aloe vera gel
Whether you extract it directly from the plant or use a product containing aloe vera, it greatly helps in moisturizing the skin and keeping it hydrated. Regular use of aloe vera gel can remove your tan in a short span of time.

If you have any further questions, ask me by clicking on'consult.

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Get Rid Of SunTan : 6 Effective Home Remedies

Cellulitis is an intense and chronic aggravation of the connective tissue of the skin, brought on by infection with a kind of bacteria (staphylococcus, streptococcus or other microbes). Cellulitis often occurs on uncovered areas of the body, for example, the arms, legs, and the face. It is basically characterised by excessive redness, swelling, warmth and pain or pain at even the most delicate touch.

Homeopathic medications are extremely productive in treating cellulitis, although these will have to be prescribed by a doctor only. The medicines work very efficiently by increasing the immunity of the patient along with a decrease in the swelling, pain and burning in cellulitis. Indeed, even in instances of cellulitis with blister formation, homeopathic medications are very effective and are usually administered in small doses of natural elements. Following are some of the homeopathic medications so as to cure cellulitis:

Belladonna for redness of skin during cellulitis: The Homeopathic cure Belladonna is a normal medicine for cellulitis where the skin is extremely red and swollen giving it a sparkling appearance. Patients that feel excruciating pain even at the slightest touch will also require Belladonna.
Apis Mellifica for cellulitis during swelling: Apis mellifica is suited for those instances of cellulitis where there is much swelling of the affected zone along with a burning and stinging pain. Apis mellifica helps those cases of cellulitis in which the smouldering pain is relieved by applying something cool over the skin and the pain that quickly spreads over various parts of the body.
Ledum Palsture for cellulitis due to insect bites: The Homeopathic solution Ledum palustre holds a very effective reputation in treating those instances of cellulitis that occur because of bug bites. This common homeopathic solution is used as a part of cellulitis when there is a cold sensation in the affected area with tearing pain.
Pyrogenium for septicaemia in cellulitis: Pyrogenium is a well-known solution for treating this condition. It is used for a number of symptoms. This could include a fever with the body temperature being 103 to 106 degrees. It rises rapidly with an unusually fast heartbeat and restlessness.
Calendula Officinalis in Post-surgical cellulitis: Without a doubt, the best homeopathic solution for cellulitis that has come after surgical cuts is Calendula officinalis. This prescription acts productively as a corrective as well as a preventive measure for pus formation on the skin after the surgery.
Silicea for treating cellulitis when blisters show up on the skin: The homeopathic cure Silicea gives great results when blisters or sores are shaped on the skin in extreme cellulitis cases. These blisters are usually filled with pus, which is quite harmful if the blister bursts. Silicea is also used when there is fever with chills and perspiration.

Treating Cellulitis with Homeopathy Remedies - 6 Best Cure

The inflammation of the kidneys as an effect of Systemic Lupus Erythematosus (SLE) is known as Lupus Nephritis. Like lupus, this is an autoimmune disease. Inflammation of the kidneys hinders kidney functioning by not allowing the kidneys to regulate the optimum amount and types of fluids in the body and restricts the removal of waste through urine. It can also cause the protein to leak out of the kidneys. If not managed in time, this can eventually lead to kidney failure by scarring the kidney tissue. However, this is a rare occurrence. 

On an average, 6 out of 10 lupus patients suffer from lupus nephritis. In most cases, this disease develops within the first five years of lupus symptoms making their appearance. The symptoms of this disease are mild and can vary from person to person. Very often, the first signs of lupus nephritis become visible only in lab tests as the symptoms are similar to those exhibited by other kidney diseases. 

Some of the common symptoms of this condition are: 

Swelling of the feet, ankles and calves 
High blood pressure 
Weight gain 
Frothy, dark urine 
There are five stages types of this disease and hence, the first step to treating this disease is to identify its type. For this, your doctor will begin with a thorough physical examination and understand your medical history. He or she will also ask for a few tests including urine tests, blood tests, an ultrasound and a kidney biopsy to confirm the diagnosis. 

Lupus nephritis is usually treated with corticosteroids and immunosuppressive drugs. Medication may also be prescribed to lower blood pressure and prevent the clotting of blood. However, in some cases, this treatment may not be enough to stop the progression of the disease and some kidney function may be lost. If both kidneys fail, dialysis is the next medical step. This involves the use of a machine in place of the kidneys to filter and removes waste products from the body. This may be followed by the need for a kidney transplant. 

Since lupus patients are at a high risk of lupus nephritis, here are a few conscious lifestyle changes that can help prevent this condition:

Have a diet that is low in salt 
Avoid smoking and alcohol 
Exercise regularly 
Avoid non-steroid anti-inflammatory drugs("pain killers") and unproven alternative medications that can affect the kidneys.

What Is Lupus Nephritis?

One of the most important functions of the skin is protection. During this process, it comes in contact with various substances including chemicals, pollen, dust, and other pollutants. While it does protect the overall body from all these, there is some damage that is inevitably done to the skin through these exposures. Different skin and different bodies react differently to these, and while some may have no reaction, others develop allergies. This is also defined by how strong the person s immunity is.

Hives is one of the most common skin allergy responses. While it is not easy to pinpoint what causes the allergy or the hives, the causative agent can be nailed by observing patterns and excluding out some of the causative agents. There are a set of regular household and surrounding items that could lead to urticaria, and working around these can help pin down the source.

Origin: When the body encounters a foreign body, it produces what are known as histamines. When they are produced, the plasma in the cell leaks out, producing a red and swollen appearance. Hives are red, itchy, raised patches on the skin. They are seen in about 20% of the population. Hives are usually allergic in nature, implying that they occur when there is a foreign substance that induces an allergic reaction. Hives can appear either due to coming in touch with some substance or due to eating some allergy-inducing substance.

Hives can be acute or chronic. Acute is when the hives appear in response to an allergic reaction. These usually disappear in a matter of days to a week at the maximum. In some people, they could be chronic and can last for months together.

Treatment: Given that they are allergic in nature, managing hives includes a combination of immediate treatment as well as preventive measures. While most are topically managed, others might require systemic intervention also.

Once the hives have developed, the following can help in the relief of symptoms and prevent from spreading further. The redness and swelling will take some time to disappear.

Avoid tight-fitting clothes
Use cool compresses on the hives
Avoid warm or hot shower
Stay in a cooler room
Avoid itching the hives
Use topical moisturizer to prevent dryness
Use topical steroid cream to manage the inflammation
Take a systemic antihistamine or an injection of epinephrine if required.
While these help in managing the hives which have occurred, preventing is via the following.

Avoid the source once identified
If the source is not yet known, record when the hives are occurring
Manage stress and see hives appear much less
Increase moisturizer use
Keep an antihistamine handy so you can take it immediately in case of suspected hives. 

Urticaria (Hives) - The Best Way It Can Be Treated!

Vitiligo, often known as leukoderma, is a specific kind of skin whitening disease resulting in white patches all over the skin. A gradual loss of pigment layers on the skin surface results in the patches. This type of skin disorder becomes socially challenging for the sufferers. As the discolouration of skin and the patches all over the body start getting noticed by people, the patients get depressed. But they should stay positive as the treatment of vitiligo with Ayurveda has proven to be one of the safest cure methodologies.

Symptoms

Vitiligo generally starts with small spots on exposed areas; especially the bone joints, which are the first areas to be affected by vitiligo. Due to the lack of blood circulation, the bone joints are inclined to get affected by vitiligo. Gradually the spots on the skin turn into white patches. This disease has nothing to do with germs or bad blood. Rather it is caused by de-pigmentation issues on skin layers.

Factors responsible for vitiligo

Women are more prone to vitiligo than men. The factors that cause vitiligo are:

Jaundice
Liver problems
Mental worry
Typhoid
Burn injuries
Parasites in alimentary canal
Apart from these above mentioned factors, hereditary factors also trigger this type of skin disorder.

Ayurvedic Treatment For Vitiligo

Decades of research and practices have established Ayurveda as one of the most ancient and holistic ways of treatment. Ayurveda means the goodness of all the natural elements and herbs. So treating vitiligo with Ayurveda doesn't only mean curing the disorder, but also the Ayurvedic medicines are known to enhance skin tones.

According to Ayurveda, Leucoderma is caused due to the aggravation of Pitta Dosha. Pitta is an Ayurvedic humor which symbolizes heat or fire, and is manifested in the skin. Aggravated Pitta leads to accumulation of ama (toxins) in deep layers of the skin, leading to the condition of Leucoderma.

Pitta is of five types; one of them is Bhrajak Pitta that gives coloration to skin. In the case of Leucoderma, Bhrajak Pitta is in an imbalanced state, and therefore, the skin starts losing its color and white patches appear. Along with Pitta Dosha, deeper body tissues like Rasa Dhatu (nutrient plasma), Rakta (blood), Mansa (muscles), Lasika (lymph) are also involved in the disease.

Treatment consists of pacifying imbalanced body energies, cleansing the blood and administrating herbs that restore skin color. Poor digestion is the root cause of this disease, as it causes the build-up of toxins in the tissues. An essential part of treatment, therefore, is restoring digestion. The patient will also be advised on the correct diet and lifestyle adjustments to prevent recurrence of the disorder.

One of the most effective Ayurvedic medicine for vitiligo is Agnijith. Its capability of producing pigmentation on needed areas is scientifically proven. It is capable of blocking the de-pigmentation issue on skin layers. This cream-based medicine is also known for contacting rich microbial properties, which get easily absorbed in skin and increase the level of blood circulation. Vitiligo is almost an autoimmune disorder, thus the Ayurvedic anti-vitiligo medicines are the best way to cure it.

There are a few Ayurvedic home remedies that are effective enough in removing the white patches. Turmeric is a common herb in everyone's kitchen. Applying a mixture of turmeric and mustard oil on the affected areas can help you cure vitiligo.

Bakuchi and coconut oil s mixture is another effective remedy for vitiligo. Apply the mixture, keep it for 15 minutes and then wash it off.

Vitiligo is a special case of skin disorder, which is triggered by a low immune system or pitta dosha. So leading a good lifestyle and eating healthy food are equally important in order to get cured.  

Vitiligo - Symptoms and Ayurvedic Treatments

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