Study of the brain has fascinated specialists all over the globe since time immemorial. The brain being the most vital organ for survival and coordination is perhaps the most complex of them all too. This has led to a limited understanding of its working in spite of the available advanced technology. However, with the advent of techniques for diagnosis and treatment, therapeutic strategies are evolving. This is a major step towards rendering Neurosurgery safer than ever in the history of mankind.

Neurosurgery through the 20th Century-

During the beginning of the 20th century, Neurosurgery was considered as a specialty. The clinical-neurologist would draw conclusions related to lesions in the brain through neurological examination and clinical history. It enabled diagnosis of vascular lesions, spinal disorders, and brain tumors. During the second and third decades of the 20th century, vascular pathologies and brain tumors could be diagnosed indirectly through techniques like angiography, ventriculography, and pneumoencephalography. But since the operative techniques were too crude and the lack of skilled professionals were rampant, there were high rates of morbidity and mortality due to neurological conditions. Generally, after diagnosing the nature of brain lesion and its site, surgery was performed with inadequate maintenance and control of intracranial pressure and through not too sophisticated surgical instruments.

During the fifth and sixth decades of the 20th century, chemotherapy and radiation treatment came into the picture for treating malignant brain tumors, thereby reducing mortality to a good extent.

During the seventh decade of the 20th century, Computed Tomography (CT) scan provided a better understanding of the location of lesions in the brain which slightly substantiated the earlier techniques. Then, the procedures for cerebrospinal fluid diversion significantly improved management of intracranial pressure during surgery.

It was only during the last decade of the 20th century that the Neurology saw a giant progressive leap through the introduction of Magnetic Resonance Imaging (MRI) and powerful high magnification microscopes. Combined with Neuroanesthesia and Intracranial Pressure Management, this aided surgeons to work on a relaxed brain. This promoted safe removal of the brain tumor and better management of vascular lesions. Moreover, the understanding of micro-surgical anatomy improved drastically, leading to a boost in confidence levels of the micro-neurosurgeons performing the operation.

Neurosurgery in the 21st Century-

The 21st century is actually a revolutionary era that uses powerful computers in almost all the fields possible. Computer-based applications such as Neuro-imaging, Neuronavigation, Intra-operative Neuro-monitoring, and Neuro-modulation are now used in standard neurosurgical practice as a part of the routine. Extremely powerful CT scans and MRIs are used for diagnosis before surgery. The advent of nanotechnology and its application in Neurosurgery is doing great and has a promising future ahead based on the current study of scenarios. Moreover, there is a possibility of most of the Neurosurgical procedures becoming minimally invasive. Frameless Stereotaxy is another technique that helps in locating the exact position of the tumor, which further helps the neurosurgeon in navigating with great precision the very sensitive, high-risk areas of the brain. Such techniques, to a great extent, have lowered mortality and morbidity, lessened the rate of recovery, and chances of infection related to Neurosurgery.

Take Away-

A number of techniques for diagnosis and precise location of the tumor in the brain have made Neurosurgery much safer today, due to advancement in science and technology, than it ever had been in the history of mankind.

Advancements In Neurosurgery - Know How Safe It Is!

Antibiotics are something which have changed are lives for eternity as well as for the better, to say the very least. With each day that passes, there are greater strides of advancement which are made in the field. Of late, it is said that antibiotics also have the potential to stop new cells in the brain from growing, which is quite a risk when it comes to their usage among people are sick.

Research has found that if the brain of the person under treatment is subject to sustained use of antibiotics, it is true that the brain can lose its functionality for a quicker time than what one would consider to be normal. So it can be said, this usually is not the advisable way to go.

Like most testing practices when it comes to medication, antibiotics which were tested on the brains of the subjects i.e. those of mice had an effect of mitigating their high-level memory. How this happened to be is rather interesting, to say the very least.

How dangerous can antibiotics be?
It is often said that eating right does wonder for a person s brain. Well, the mice that were not treated with the antibiotics were seen to lose the healthy bacteria present in their stomachs. In addition to this, they lost new brain cells. This led on to them performing worse in mental tests than their peers who had had some antibiotics administered to them on a consistent basis.

Now a cynic may point out that what is seen to be true for mice may really not hold true when it comes to humans being considered. However, if it is taken into due account that a lot of path-breaking research is carried out on mice, there is quite some credence to the results of the study.

To supplement the evidence even further, it was also seen that for mice which were in possession of low levels of monocytes, which are a type of white blood cells. It was seen that there was a great dependency on monocytes for the generation of white blood cells. The part of the brain which is hindered by generating new cells on account of the sustained use of antibiotics is the hippocampus.

Antibiotics are the proverbial shot in the arm which can aid recovery by destroying the threat to a person s wellness. However, it is to be considered that they are not safe in general as there is collateral damage!

Antibiotics - Can They Stop The Growth Of Brain Cells?

Neurological disorders may creep in due to many reasons. It may be due to degenerative diseases, accidents, other health conditions, birth defects or genetics. The most common form of disorder occurs due to non-functional brain cells in some parts, and loss of myelin sheath in neurons, which protects the nerve signals in their complete transfer from origin to destination. These losses are irreparable, but further degeneration can be avoided with Ayurveda. Panchakarma, the branch of Ayurveda, which deals with detoxification of the body and mind, specially helps. Over a period of time, it can bring back the lost sensation in nerves. Yoga, pranayama and Ayurvedic treatments lead to recovery and relief to a huge extent.

Important facts about Panchakarma
There are 3 important steps in Panchakarma, which are followed one after another to get the result. The main objective of Panchakarma is to detoxify the body. Virechanam, vamanam, sneha vasti, nasyam and kashaya vasti are the 5 folds in Panchakarma.

Poorvakarma or preparing the body, followed by Abhyangam or massage, followed by Elakizhi or herbal paste massage, and finally podikizhi, or steam bathing makes the body ready for receiving further treatments.
Njavara Kizhi is the special treatment done in Panchakarma where the body is given a rice bolus massage to improve the joint and neuro functions.
What is Njavara Kizhi?
Njavara is a variety of rice, which is specially used for Ayurvedic treatment and massages. In this treatment the rice is made into a pudding by boiling it with milk. This pudding is then made into boluses. The boluses are filled in muslin cloth, and then using these muslin bolus dabs, the whole body of the patient is massaged. This full-body massage has excellent effects on neurological and joint functions. The deep tissues within the body are rejuvenated. The treatment is carried on for 45 minutes to 60 minutes by therapists or experts. Another form of the treatment requires the rice to be made into a paste, and then the paste is applied all over the body. But this is more preferred for beautification.

Other effective therapies
Siro Vasti, Kati Vasti, Ela Kizhi and Nasyam are all different forms of Panchakarma treatment, which detoxify the body and mind and rejuvenate the body and nerve functions. But these treatments cannot be conducted on the body on your own. You need a masseur who must be a specialist in Ayurveda to do this for you. Hence contacting Ayurvedic clinics, doctors or experts would be the best to start the treatment.

Neurological Disorder - How Panchkarma Therapies Can Help?

Surgery to remove abnormal growths of the brain, peripheral nervous system or the spine or any disorder can be tricky because the brain and the skull that shields it are complex areas. In the old days, open surgery was the only way to access the brain or spinal cord. But, with the invention of laparoscopy, keyhole surgery to treat neurological issues is gaining ground.

What is Neuroendoscopy? 
Neuroendoscopy is a surgical procedure that is favoured by doctors and patients alike because it is minimally invasive.
Before the surgery, you will be administered general anaesthesia so that you will be unconscious during the entire duration. During the surgery, the surgeon will drill a minute hole into your skull just above the eyebrows. You skull also has two natural openings. That is why the surgeon may make use of the nose or the mouth to access the region that needs to be operated upon.

Neuroendoscopy is useful because -

  It lets the surgeon reach regions that are not accessible with open surgery
  The tumour can be removed without any damage being done to surrounding tissues

An endoscope is a delicate device with a high-resolution camera mounted on it. There is an eyepiece on the other end. The device is also fitted with a light. When it is inserted into the brain, it lights up the passage and the eyepiece allows the surgeon to take a look inside. The camera sends a live feed of the path it is traversing and this guides the surgeon. When the tumour is reached, it is gently removed with other surgical instruments that too were inserted through the cavities or the drilled hole.

Benefits of Neuroscopy -
There are several advantages of relying on laparoscopy -

  The patient endures less pain
  Fewer chances of infection
  Faster recovery
  Very little scarring of tissues

Which Disorders call for Neuroendoscopy?
Any of the following disorders can be put to rights with a neuroendoscopic surgery -

  Pituitary tumours
  Rathke s cleft cysts
  Pineal area tumours
  Ventricular tumours
  Skull base tumours
  Brain inflammation triggered by an infection
  Chordomas
  Cerebrospinal fluid fistulas
  Trigeminal neuralgia
  Cerebral aneurysm

After Surgery-
Once you undergo the neuroendoscopic surgery, you will have to be rehabilitated so that your condition can be monitored round the clock. Neuroendoscopy is a state of the art clean and efficient surgery that is beneficial to both surgeons as well as the patients.

Know More About Neuroendoscopy And Its Uses!

Neurological disorders are the diseases of the brain and spine, and the nerves which connect the brain and spine.

Some of the most common types of Neurological disorders are:

Alzheimer s Disease (AD)

Multiple Sclerosis

Epilepsy

Migraines

Parkinson s Disease

Ayurvedic Approach of Neurological Disorders

Ayurveda is an ancient system of medicine which originated in India, having a holistic approach to focus on treating the entire being. Ayurveda treatments are based on vata, pitta, and kapha doshas, whose balance leads to harmony and whose imbalance leads to toxic accumulations inside the body. Ayurveda aims to maintain an equilibrium among the three. It has effective solutions for a number of Neurological Disorders, also called  Vatavyadhi .

Eighty types of Vatavyadhi are described in Ayurvedic texts which can be placed under four categories: Kevala vata (Vata alone), Samsarga (Vata in association with Pitta and Kapha), Avarana (due to entrapment by other Dosha/Dhatu/Mala), and Dhatu Kshaya Janya (neurodegenerative). 

Ayurvedic Treatment

Ayurveda is plant-based systems of medicine. Because of being natural and harmless, it is very popular in treating various diseases. Several herbs have excellent properties to treat panic and anxiety affecting the central nervous system. Nature s gift of herbs and minerals not only alleviates symptoms but ensures cure by regulating neural biokinesis, thus preventing recurrence, relapse, and adversity.

Ayurveda can cure a number of Neurological Disorders like migraine, sinus, Parkinson s disease, anxiety, stress, insomnia, epilepsy, hysteria, cerebral palsy, stroke, etc. For treating these Neurological Disorders Panchakarma therapy is adopted which focuses on holistic treatment for long-lasting results.

Some of the common remedies under Panchakarma therapy are:

Chamomile tea, roots of kava, passion flower, ginseng, Cannabis sativa are all prescribed for anxiety.

Valerian is used as a natural sedative and for treating insomnia and panic attacks.

Ginkgo biloba and Hypericum perforatum have neuroprotective properties and are useful in treating learning dysfunction and improving memory.

Inhaling powder of seeds of Achyranthes aspera or Prickly chaff flower relieves from stiffness and migraine.

Bark powder of Acorus calamus or Sweet flag root enhances memory by curing forgetfulness. When consumed with honey, it is beneficial for anxiety and epilepsy. Equal weights of this powder with ginger powder is recommended for facial paralysis.

Powder of Malabar nut with honey cures epilepsy.

Seed powder of Siris tree is used for treating insanity, psychosis, anxiety, and hysteria.

Coriander extract relieves vertigo and headache.

Juice of Dodder plant or Amarbel is taken in water to improve brain disorders.

Extract of branches of peepal tree cures madness.

Decoction of roots of drumstick plant is given for epilepsy and hysteria.

Velvet bean is effective in treating Parkinson s disease.

Poppy is beneficial in sleeplessness, delirium, convulsion, etc.

Decoction of leaves of guava is used to cure physical and mental deformities.

Leaves of pomegranate, when concentrated in boiling water and given in warm milk, cures fatigue and insomnia.

Leaves of pomegranate and rose petals when concentrated in boiling water and given in ghee, cure madness.

Cloves paste in water is applied on earlobes to cure migraine.

Almonds improve memory, especially when taken at an early age.

Yoga and meditation help in improving mental health by incorporating discipline and relaxation.

Take Away

For reliable cure with minimal side effects, Ayurveda is very well developed for treating many brain-related disorders with an approach of maintaining equilibrium among the three doshas and towards holistic, long-term treatment.

Neurological Disorders - How Ayurveda Can Assist?

Brain tumor refers to the development of unusual cells in the brain or around the nearby tissues and structures. Pediatric Brain Tumor means the development of these unusual cells in the brain of children. There are two types of brain tumors: Benign or non-cancerous and malignant or Cancerous. Tumors like ependymoma and medulloblastoma are quite common among children. The treatment of the tumor is determined by its severity, type, location, age, and overall health of the child. The treatment of Brain Tumor in children is different from the adult s treatment. One should ensure to consult with the pediatrician with the specialty in cancer and neurology. Brain Tumors in children are Primary Brain Tumors that develop in the brain or nearby tissues. This Primary Brain Tumor develops when the usual cells have DNA mutations or alterations. The alterations in the DNA permit the cells to develop and distribute or split with an increased rate and destroy the healthy cells. This leads to the development and collection of unusual cells forming a tumor. In most Primary Brain Tumor cases, the cause is not clear. Children with a family history of the genetic syndrome and Brain Tumor are more prone to the problem.

Symptoms-

The symptoms of the Pediatric Brain Tumor depend upon the severity, location, and type. There are a number of symptoms that are really common and are shared by other diseases. Other than this, there are symptoms which are possibly the signs of Brain Tumor among children. Adults and parents should consult a doctor if they find their children having the symptoms and signs for an unusual time.

Hearing issues

Frequent and severe headache

Fuller fontanel (soft spot) on the baby s skull

Vomiting or nausea

Behavior changes

Seizures

Sudden vision problems like double vision

Abnormal or strange eye movement

Increased heaviness or pressure in the head

Irritability

Slurred speech

Difficulty in swallowing

Weakness

Loss of appetite

Drooping on one side of the face

Difficulty feeding in babies

Loss of sensation on one side of the body

Imbalance or difficulty in balancing

Difficulty in walking

Diagnosis-

The diagnosis for the Pediatric Brain Tumor includes many lab tests. The doctor may initiate with some neurological examination like hearing, vision, reflexes, balance, and coordination. Any abnormality in these tests will lead to further examinations. There are some imaging tests that are used to determine the size and location of the tumor in the brain. These tests include MRI (Magnetic Resonance Imaging), PET (Positron Emission Tomography), and CT (Computerized Tomography). After the confirmation of the presence of a Brain Tumor, the specialist will further move to the Biopsy. It includes the removal of a sample tissue for analysis or testing. The type of biopsy that will be performed on the patient depends upon the location of the tumor. Other than the biopsy, the tumor tissue can be examined for molecular basis and genetic mutations. After that, Drug therapy can be designed according to the individual s requirements. It is important for the doctor and the patient to know if the tumor has been spread through cancer in other parts of the body. If it is true, then the doctor will perform more tests and examinations to know the root and initial location of cancer for further treatment.

Treatment-

The treatment of the Pediatric Brain Tumor is determined by the severity, location, size of the tumor, and age and health of the child. There is a number of treatments available with modern technology but their usage depends upon the patient s requirement.

Surgery that is used when the location of the tumor is approachable via surgery. When the brain tumor is small, it can be completely removed by the surgery. But when the tumor tissues are located nearby sensitive areas of the brain, then the surgery becomes risky and maximum tumor tissues are tried to be removed through surgery. The risk of the surgery depends upon the location of the tumor. An example can be vision loss if it is anywhere near the nerves connected to the eyes.

Targeted Drug Therapy helps to destroy the abnormalities of the cancer cells resulting in the destruction of the cancer cells.

Radiation therapy is used to kill the tumor cells by using high-energy beams. Radiation therapy can either be given by an external machine (external beam radiation) or in exceptional cases, radiation is positioned within the body (brachytherapy) near the tumor.

Chemotherapy includes the consumption of drugs to destroy the tumor cells. These drugs can be consumed in tablet form but for children, the drugs are mostly injected (intravenous chemotherapy).

Stereotactic Radio Surgery includes various radiation beams to perform extremely focused radiation therapy to destroy the tumor cells located in a small part.

Proton Beam Therapy carries higher targeted radiation doses to the tumor cells with minimum exposure of radiation to the healthy cells and tissues. It decreases the chance of development of fresh cancer cells.

Take Away-

Pediatric Brain Tumor is the development of unusual cells in the brain or around it. Although this is a life-threatening problem, however, with advanced technology, it can be treated successfully. There are no specific causes discovered by specialists but genetic mutations and family history cause it. The symptoms can be really common like headache and nausea but can also be specific like difficulty in coordination, reflexes, speech, and many more. The timely diagnosis and treatment can give a new life to the child and reduces the chance of development of fresh tumor cells in the future.

Pediatric Brain Tumor - Know In Detail About It!

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