There can be a number of reasons that lead to infertility in women. Endometriosis is one of them. It is a benign condition where the endometrium, which includes the tissues that form the lining inside the uterus, grows outside the uterus. Apart from infertility, it may also cause pelvic pain in women.

There are no such symptoms of endometriosis apart from pelvic pain and it cannot be detected without surgery. Thus, it is very difficult to diagnose this disease and state how common it is. However, research says that the prevalence of this disease in women in their reproductive age is between 3 to 10 per cent.
It is found that endometriosis sometimes leads to infertility. Here is how:

Abdominal Adhesions and Infertility
Normally, the endometriosis implants develop in the abdomen. Then the body surrounds them with connective tissues. The reason for doing so is isolating the implants, so that they cannot harm your body.
Now, sometimes these adhesions can create a blockage in the opening of the fallopian tube or may also pinch off the fallopian tube. This will result in obstruction in the fertilisation of egg and the sperm and thus fertilization will not take place; so there are no chances of conceiving. These obstructions when diagnosed can be treated with surgery.

Secretions from implants
Endometrium plays a vital role in conception where the tissues secrete a wide variety of hormones and nutrients. Now, the endometrial implant also functions in the same way and secretes those hormones. The difference is that it does not deposit them in the lumen of the womb, and it is released in the abdominal cavity. In these substances, there may be some hormones that are responsible for infertility.

Prostaglandins
Prostaglandins are other hormones that are secreted by the endometrium normally. It helps in a lot of body processes that include various stages of menstrual cycle and pregnancy. This hormone is required for a lot of functions such as ovulation, sperm mobility, and regression of corpus luteum, immune interaction, menstrual cramps and contraction of the uterus at birth.

Just like the endometrium, the implants also secrete these hormones. And, the problem that is caused by the implant secreted prostaglandin hormone is that they are released in the abdomen and not in the womb. Moreover, they are not secreted at the right time, thus sending a wrong message to the brain.

A woman with a few days of pregnancy may face a miscarriage because the ovary will get a signal to start the menstrual cycle, and the womb lining where the egg is implanted will be expelled.

How Endometriosis Leads to Infertility and Miscarriages?

Every woman desires to experience the sweetness of motherhood but unfortunately, some fail to get it. It is because either they have low fertility or because they have developed a disease or disorder like endometriosis and Polycystic Ovary Syndrome (PCOS) due to which they fail to conceive.

Endometriosis is always associated with infertility. To get relief from troublesome problem is to get pregnant earliest may be by IUI if tubes are patent or by IVF. Endometriosis is conditions which lead the womb cells (endometrial cells) to develop in other parts of the body because of which women experiencing this disease fail to release the menstrual blood and also fail to conceive. But these days nothing is impossible it this medical advancement era. There are many ways and methods by which one can conceive.

So here we are providing a useful set of information on some of the best Fertility treatments.

Intrauterine Insemination or Artificial Insemination: It is a normal process in which the sample of a prepared sperm from the husband or the partner is injected directly into woman s uterine cavity during ovulation.
In Vitro Fertilization: In this process, specific medication is used for the stimulation of the ovaries which lead them to produce more eggs in a while. Then eggs are then removed and fertilized with the husband or partner s sperm in a laboratory. The fertilized eggs are placed for 3-5 days to develop an embryo and then the embryo is transferred to woman s uterus.
It is considered as one of the best and last stop infertility solution which proves to be a boon for a sterile couple. As in this process, fertilization takes place outside the body because of which there is no problem of conception even in the condition of any blockage and also minimizes the risk of endometriosis-related infertility. The endometriotic deposits produce and releases toxin into the uterus, fallopian tubes and ovaries thus the egg gets toxic and fail to fertilize the sperm. 

In such condition, many patients rush for many other infertility treatments like fertility medications, intrauterine insemination, etc and when they lose hope of getting the desired result then they find a ray of hope by this ultimate treatment. There are five times more chances of conceiving by this method regardless of the age of women and the stage of endometriosis. The treatment is a boon not only for woman grappling with endometriosis but also for other critical issues like severe male infertility factor, blocked fallopian tubes, and reduced ovarian reserves. In such cases instead of wasting the money on other treatments doctors advice for IVF.

IVF minimizes the chances of miscarriage and also increases the chances of having a healthy baby. So if you are grappling with any such infertility issue than this informative guide may aid you in the journey from infertility to hearing child squeal at your home.



Endometriosis - How IVF Is Beneficial In This Case?

A woman s body goes through a number of changes during her lifetime and therefore, it is always better to undergo regular health check-ups at proper intervals to ensure that all organs of her body function well.

Endometriosis is something, which every woman is likely to have heard about. However, not many women are aware of what it exactly is. Even fewer know about what they should look out for when it comes to having endometriosis or understanding what it means to be suffering from it. Is it not a lot better to be informed about all of this?


The condition of endometriosis is when the tissue that is supposed to be inside the uterus also known as the womb and lining starts existing outside it. What effectively happens is that the lining of the uterus, known as the endometrium, finds itself to be trapped in the pelvic area.


Some amount of discomfort is usually experienced by women who are menstruating. However, when a woman has endometriosis, the amount of pain is pretty persistent, sometimes extending to a month-long duration. Some women also suffer from excess bleeding.


Unfortunately the symptoms are not only limited to this. Women who are adversely affected by endometriosis usually find having sex painful as well, ironic as it is supposed to provide pleasure.

Also fertility is the primary function affected by it. There are so many complications in this regard. It is said that about 50 percent of women who have endometriosis have trouble getting pregnant and carrying a baby. Effectively, as sad as it is, endometriosis has the potential to take away the entire prospect of motherhood from a woman.


In addition to this, a fair number of cases, show that the symptoms, which are experienced worsen over the course of time. So, what this means is that the lifestyle of the woman may be severely affected as the symptoms get progressively worse; which is just one of the reasons why treatment is something, which should be resorted to sooner than later.


One of the lifestyle changes which may be beneficial in reducing the severity of endometriosis includes a change in your diet. Increased intake of green vegetables and fresh fruits along with a reduced consumption of red meat is definitely worth a try. Regular exercising is also helpful in treating the condition.


Endometriosis - What are the Symptoms and Consequences of it?

Endometriosis is a painful condition where the endometrium tissue lining the walls of the uterus, grows as implants outside the womb of the patient. This can lead to a number of painful conditions and is often considered as a common cause behind severe pelvic pain, as far as women are concerned. Here is all you need to know about endometriosis and pelvic pain.

 Painful menstruation: depending on the stage of the condition, the implants could remain on the surface or go deeper into the ovaries which may cause acute and severe problem during ovulation as well as the menstrual cycles. This is one of the symptoms that one must not ignore. If you are having painful cramps that affect the pelvic area and the abdomen, and if these cramps last throughout the duration of the cycle, then there are strong chances that you are experiencing the pain that comes with endometriosis. 
 Pain during and after intercourse: while there are many reasons why women may face pain during intercourse, it may be noted that vaginal and pelvic pain that come during and after intercourse could point towards the presence of endometriosis, which is causing irritation and discomfort due to the implants. 
 Bowel movements and urination: usually, pelvic pain may trickle down to and also get activated by the bowels when there is a motion as well as urination. This is a common problem that can cause pain, which spreads throughout the region if the patient is suffering from endometriosis. 
 Bloating and other symptoms: when the abdomen and nearby regions face bloating due to the implants and their painful spread, the pelvic region as a whole bears the brunt in terms of severe pelvic pain. The bloating and other symptoms like loose motions and constipation can also create pain in the abdomen and pelvic region on a persistence basis. Sharp pains may also shoot up and down the lower back due to such symptoms which should not be ignored if they do not abate within a few days. 
 Misdiagnosis: many times, the bloating and pelvic pain may be linked with pelvic inflammatory disease, which causes pain in the muscles and joints. But if you are having pain in the abdomen as well as problems during your menstrual cycle, then it may be helpful to have the tests for endometriosis done as well. 

In order to diagnose the condition, the doctor must ensure that proper imaging tests like mri and ct scans as well as an ultrasound with lab tests based on blood samples have been conducted. The pelvic pain that comes with this condition can be treated with the help of pain relievers like ibuprofen and aspirin.

Could Your Pelvic Pain be Endometriosis?

An often painful condition usually involving the bowel, ovaries or the tissue lining the pelvis, endometriosis is characterized by the abnormal growth of the endometrial tissue beyond the premises of your uterus or your pelvic region. The endometrium, in fact, functions perfectly normal with each menstrual cycle, but because of it being displaced, it cannot exit the body and consequently gets trapped.

Besides causing severe pain and distress, endometriosis can also adversely affect fertility. When the ovaries get involved, certain cysts known as endometriomas tend to develop which often result in the formation of scar tissues and adhesions.

Complications associated with it

Infertility: Impaired fertility is the most common kind of complication arising from endometriosis, with approximately one-third to one-half women having problems with pregnancy. During endometriosis, the fallopian tube gets obstructed, thereby restricting the union of the egg and sperm.
Ovarian cancer: Women with endometriosis are more likely to suffer from ovarian cancer. Moreover, they are also more susceptible to acquiring endometriosis related adenocarcinoma, which is another variant of cancer, but a comparatively rarer phenomenon.
How best to treat it?

Depending upon how severe your symptoms are, endometriosis can be treated via the use of medications or through the advent of surgery.

Pain medications: Certain medications, including pain relievers and anti-inflammatory drugs, are particularly useful in providing relief to painful menstrual cramps.
Hormone therapy: Undergoing hormonal therapy can help ward off or reduce the pain of endometriosis, but it should be kept in mind that it is only a temporary fix and that symptoms might reoccur. Hormonal therapies include:
Hormonal contraceptives
Medroxyprogesterone
Gonadotropin-releasing hormone (Gn-RH) agonists and antagonists
Danazol
Conservative surgery: This can either be done through laparoscopy or, in more extensive cases, through traditional abdominal surgery.
Assisted reproductive techniques: These include in-vitro fertilization, and are sometimes more preferable over conservative surgery.
Hysterectomy: This is usually done in more severe cases of endometriosis whereby ovaries are also removed with uterus and cervix

Complications and Treatment of Endometriosis

When endometrial tissue that usually grows inside the uterus, starts growing outside uterus, it is called Endometriosis. Pain during or before periods, pain during intercourse, pain while urinating or bowel movements, heavy bleeding, infertility are some of the symptoms of endometriosis.

Treatment of endometriosis usually depends on the following factors:

Age of female
Severity of symptoms
Duration of the symptoms
Future plans for children/ fertility
Associated pathologies
Accordingly the doctor might choose any of the treatment options like:

Medication for Pain: If the symptoms are mild, then the doctor will prescribe some pain  relieving medications like Nonsteroidal anti-inflammatory drugs (e.g. Diclofenac) or anti-spasmodics(e.g.drotaverine)
Hormone Therapy: Hormone therapy is effective, but once you stop them, your symptoms may recur. Some of the hormone therapies include: 
Hormonal Contraceptive pills: Useful in controlling the hormones that are responsible for endometrial tissue growing outside the uterine cavity.
Medroxyprogesterone: This helps to counter effect estrogen hormone which is responsible for endometrial tissue growth.
Gonadotropin-releasing hormone (GnRH) agonists: Gonadotropin hormones that stimulate ovaries are blocked by these. They bring down oestrogen levels and hence symptoms. It can cause absence of menstruation in some females which is reversible.
Danazol: It is synthetic androgen, suppresses growth of endometrial tissue temporarily.  However, Danazol may not be a favourable option because of its side effects. Females should avoid pregnancy while on this drug.
Dienogest: This newer progesterone molecule, which does not have major side effects and is apporved for use in endometriosis.
Other medications like selective progesterone receptor modulators, immunomodulators, anti angiogenic factors are being evaluated.
Conservative surgery: If you are trying to conceive, then surgical excision or ablation of endometrial tissue is one treatment option.Suboptimal surgery with conservation of maximum ovarian tissue is considered suitable in such cases.
Hysterectomy: In severe endometriosis cases where female has completed her family, hysterectomy is offered wherein the uterus, cervix & if required ovaries can be removed.

Endometriosis - Ways To Manage It Well!

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