At present 3 out of the 5 people are suffering from diabetes and it is the 7th leading cause of death worldwide. Moreover, it is no more restricted just to adults and affects children as well. Diabetes is a metabolic disease resulting in increase in the level of glucose in the body. Glucose is a source of energy for the cells making up the muscles and other tissues in the body. But if the level of glucose goes up, it shows the sign of danger. Diabetes is of 2 types: 

1. Type 1: body fails to produce insulin.
2. Type 2: Body fails to produce enough insulin which is required by the body.

There are no definite signs of diabetes. It simply varies from person to person. In many of the cases it goes unnoticed. Such signs are as follows:

1. Sudden weight loss: You might experience a sudden weight loss of 5 to10 kgs within a month. This happens when sugar metabolism ceases very quickly.  Insufficient insulin prevents the body from taking in glucose in the body cells from the blood to use as energy. In such a scenario the body starts burning fat and muscle for energy. This results in weight loss.

2. Intense hunger: The cells in your body might not get enough energy either due to absence or improper functioning of insulin in your blood. This makes you hungry quite often.

3. Excessive urination and thirst: Due to diabetes, the glucose level in the body goes up. The kidneys are overloaded with the burden of working overtime for filtering and absorbing the excess glucose in your body. The excess sugar, which the kidney cannot store is excreted out of your body. This makes you urinate frequently.  Due to frequent urination the body gets dehydrated which makes you feel thirsty more often.

4. Blurred vision: Due to the high level of glucose in your body tissues gets pulled away from the lens of the eyes. This results in vision issues. If not treated on time, it may even lead to blindness.

5. Increased fatigue: The cells in your body might not get enough energy either due to absence or improper functioning of insulin in your blood. This makes you restless more often and you may even feel too weak to do your regular activities.

If you notice any of these signs, get the level of sugar in your checked and take the required remedies. It is good to get it treated as early as possible rather than facing immense trouble in future.

5 Common Signs of Diabetes That Often Go Unnoticed

Top 5 things all diabetics must do

As you are aware, diabetes is an increasingly common problem not only in adults but with children and young people too. Preventing or delaying diabetes is possible with a few lifestyle changes. And for those who have been diagnosed with type-2 diabetes, changes in lifestyle can prove beneficial to keep it under control. This is important and should not be taken lightly as diabetes can lead to other serious health complications. There are few simple things which if done regularly can keep you safe and absolutely fine.

5 ways to combat diabetes.

1) exercise - do minimum 45 to 30 minutes of exercise like brisk walking (for people with heart ailments make sure that you have done stress test/tmt). Keep yourself physically active all the time this will help you in losing weight, controlling blood sugar, blood pressure, cholesterol. It will also improve insulin sensitivity in your body. 
2) high fiber diet - include high fiber foods like fruits, vegetables, leafy vegetables, beans, nuts, seeds, and whole grains, cinnamon, green tea in your diet. This will improve your blood sugar level and also reduce your risk of developing diabetes and helps you to lose weight. Do not get into fad diets and tv commercials as they are often misleading.
3) reduce stress - tension and worry releases certain chemicals (stress hormones) which can increase your blood sugar level. Try relaxation therapy like meditation, yoga, music and soundful sleep.
4) restrict intake of alcohol - alcohol increases body weight, triglyceride (cholesterol) level and blood pressure. They may make you unaware of symptoms of hypoglycemia (low blood sugar which may be dangerous). They are empty calorie with no nutritional value. Permissible limit is 2 drinks (60ml) a day for men and 1 drink (60ml) for women, it is also not advisable to smoke.
5) regular check-ups - make sure that you regularly check your blood sugar levels and modify treatment from your diabetologist doctor (if required.) your body and your friend/ relative / colleague's body are different, so is your need of medicine for diabetes as well. What works best for them may not be right for you. So it is my sincere request is to avoid any self medication as it can be dangerous. Regularly undergo screening for early detection of diabetes complications like eye, nerve, heart, foot, kidney.

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Top 5 Things All Diabetics Must Do

Insulin is the most common treatment prescribed for people affected with diabetes. Diabetes is condition where high amounts of glucose prevail in the blood for an extended period of time. However, there are some drugs that offer an alternative to insulin in treating diabetes, which are:

1. Liraglutide: Liraglutide is a glucagon-like peptide-1 (GLP-1) drug that causes the body to release greater amounts of insulin so as to facilitate the movement of glucose from the blood to the cells. People with type 2 diabetes generally use this treatment. It slows the digestion process and can cause symptoms of headache and nausea. 

2. Pramlintide: It's an artificially produced version of amylin. It is taken by both type 1 and type 2 diabetic patients, facilitates slower digestion of food and therefore, controls release of sugar in the blood. It can cause tiredness and nausea.

3. Dulaglutide:This treatment is for people affected with type 2 diabetes and it is administered once a week. It causes more insulin to be released and pass the glucose to the cells. It can cause loss of appetite, nausea and abdominal cramps as side effects.

4. Albiglutide: This treatment facilitates pancreas to release insulin and limits the glucagon hormone production. It is used by type 2 diabetes patients who have not taken well to other treatments. The side effects are skin reaction, respiratory tract infection and nausea.

5. Exenatide: It is a drug that causes pancreas to release insulin that facilitates movement of glucose to cells. It is a treatment for type 2 diabetes and it restricts release of glucagon in the body. The possible side effects are acidity, constipation and vomiting.

Common Insulin Alternatives

Often, a medical crisis does not happen suddenly, and your body shows a few symptoms well before it reaches the critical phase. However, there are conditions when the symptoms occur quite suddenly, and one such is the Addisonian crisis.

Addison's disease is a condition that occurs when the body fails to produce sufficient levels of certain hormones that are secreted by the adrenal glands. In this disease, the adrenal glands produce too little cortisol and even low amounts of aldosterone at times. Often referred to as adrenal insufficiency, it may occur at any age, and both sexes are affected by it. The worst part is that the disease can be life-threatening.

The symptoms of Addisonian crisis-
While severe fatigue, hyperpigmentation, severe fatigue, lightheadedness, salt cravings, and muscle and joint pains are the common symptoms of Addison s disease, pain in your lower back, severe vomiting and diarrhea, low blood pressure, and high potassium and low sodium are the symptoms of acute adrenal failure (Addisonian crisis).

The low levels of cortisol associated with the Addisonian crisis are life-threatening; hence, when you experience one or more of these symptoms you must seek professional care immediately.

Treatment options that are available for Addison's disease-
Nearly all treatments for Addison's disease involve hormone replacement therapies for correcting the steroid levels that the body is not sufficiently producing. Some of the most effective treatment options for Addison's disease include:

Oral corticosteroid medicines- Prednisone, Hydrocortisone and Cortisone acetate may be used in the pill form for replacing cortisol. Sometimes, doctors also prescribe fludrocortisone for the replacement of aldosterone.
Corticosteroid injections- This is given to people who cannot take oral pills.
People diagnosed with Addison s disease are at risk of developing Addisonian crisis. Such people must be well-aware of how to tackle the condition if they are to face it. Some people have a home kit which includes hydrocortisone injection. One should not wait too long or wait to feel very weak before taking the injection. Also, it is important to call the emergency after taking the injection to get further treatment.

What should you do to prevent and manage the Addisonian crisis?

If you indulge in heavy workout sessions, you should take ample amount of sodium. This is also recommended when you are experiencing a stressful situation, including any infection, operation or some minor illness.
You should not skip your meals or indulge in binge eating, but focus on having a well-balanced diet. You should also take plenty of healthy fluids throughout the day. Avoid exercising or doing any physically strenuous job in hot and humid weather. Also, you need to balance your active stretch of time with adequate rest.

Taking the prescribed medications on time, and carrying a hydrocortisone kit is crucial. Also, you may carry a card stating the condition that can help during an emergency.

Addison s disease, in most cases, cannot be cured; so, it is vital to be aware of the symptoms and the ways to manage them to avoid an emergency.

Addison Disease - Treatment Options, Management and Prevention

Addison s disease is known as adrenal insufficiency or hypocortisolism. It is a hormonal disorder which occurs when adrenal glands which are located just above the kidneys do not produce enough of the hormone. The hormones produced by adrenal glands include cortisol and aldosterone, which are essential for a healthy life.

The disease is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and darkening of the skin also sometimes. Most cases of Addison's disease are caused by autoimmune disorders.
It is quite a rare condition. Only 1 in 1 lakh suffer from this condition. this condition can affect a person of any age group irrespective of sex. To live a normal life people, with this condition, a patient will be required to take their medication regularly.

Cortisol and Aldosterone - What do they do?
The most important function of the cortisol in the body is to respond to stress. It helps the body in using protein, carbohydrates, and fat. It maintains blood pressure, cardiovascular function; and controls inflammation. While as aldosterone helps kidneys in regulating the amount of salt and water in the body   which helps in regulating blood volume and keeping blood pressure under control.

Cause of Addison's Disease
Mostly Addison s disease occurs due to problems with adrenal glands themselves   which is known as primary adrenal insufficiency. While Autoimmune disease accounts for 70% of Addison s disease. In this condition, the body's immune system mistakenly attacks the adrenal glands. This attack destroys the outer layer of the glands.

Some long-term infections such as tuberculosis, HIV, and some fungal infections harm the adrenal glands. It is also caused by the cancer cells that spread from other parts of the body to the adrenal glands.
Less commonly, adrenal glands can also be affected by secondary adrenal insufficiency. It is caused by a problem with the pituitary gland or a problem with the hypothalamus, both located in the center of the brain.
These glands produce hormones that control the production of hormones in the rest of the body. A pituitary hormone called ACTH which turns on cortisol production in the adrenal gland. If ACTH levels are too low, the adrenal glands do not function.
One more cause of secondary adrenal insufficiency is also caused by the prolonged or abuse of steroid hormones such as prednisone.
Symptoms of Addison's disease
The symptoms of adrenal insufficiency grow gradually and the main characteristics are:

Chronic, worsening fatigue
Muscle weakness
Loss of appetite
Weight loss
About 50 percent of the time, one will notice:

Nausea
Vomiting
Diarrhea

A Quick Guide To Addison's Disease!

'Congratulations! You're pregnant!' Almost all women long to hear these words and nothing should come in the way, even diabetes. So, if you are a Type 1 or Type 2 diabetic, here are a few things you should keep in mind to have a healthy baby.

1. Your blood sugar must be monitored regularly-
The most important thing you can do to have a healthy baby is to keep your blood sugar as close to normal before and during your pregnancy. Testing is recommended a minimum of four times a day. Glucose passes through the mother's blood to the fetus and hence if your blood sugar fluctuates, so will your baby's. High blood sugar levels are especially harmful during the first 8 weeks of pregnancy when the baby's brain, heart, kidneys and lungs are formed.

2. Your pregnancy is considered high risk-
High blood sugar levels can increase the risk of a miscarriage as well as the risks of your baby being born with birth defects. Diabetes can also increase the risk of developing preeclampsia during the second half of your pregnancy. This could result in a C section or premature birth. Thus, maintain regular checkups and keep your doctor in the loop of all your activities.

3. You should watch out for signs of ketosis-
When you have low blood sugar, the body produces ketones that can be passed on from you to your baby. This production of ketones is a result of the body's burning of fat instead of glucose to provide energy and can develop a condition called ketosis. Symptoms you should watch out for are stomach aches, nausea, fatigue, muscle stiffness, frequent urination and fruity breath.

4. You need Vitamins and Supplements-
Most women require vitamin and mineral supplements at the time of pregnancy. Of these, folic acid, iron, calcium and vitamin D are the most important. These supplements help in the healthy growth of the baby.

5. You should exercise regularly-
Maintaining a regular physical activity routine is very important for diabetics who are expecting a baby. This will help you regularize your blood sugar, relieve stress and strengthen your heart. Avoid activities that increase your risk of falling and aim for at least thirty minutes of daily exercise such as walking, swimming or yoga.

6. Check your medication-
Some medication can be detrimental during pregnancy such as cholesterol and blood pressure medication. Consult your doctor to find a suitable alternative if needed. You may also need to change the kind of insulin you take and its frequency and amount. As you get closer to the delivery date, your insulin requirement may even double or triple.

The key to preventing complications during pregnancy is controlling your diabetes. So take your insulin regularly, maintain regular checkups and eat healthy. You need to be seen by your obstetrician more frequently. Your pregnancy will be monitored closely by more frequent ultrasounds and NST. If your sugar level remains under control and pregnancy is advancing well, a natural onset of pains is aimed for and normal delivery is expected.

Diabetes - How To Handle It While Pregnancy?

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