When a childless couple is not able to conceive, there are myriad paths that the couple may follow to obtain a solution. If IVF does not help the couple, then they can go in for surrogacy. In this method, another lady conceives, carries and gives birth to the baby created by the sperm and eggs of the intended parents. Let us find out more about surrogacy today.

Who can use it?
Surrogacy can be availed by couples who are not able to conceive due to many conclusive reasons including the absence of a womb or the malfunctioning of the same. Also, recurrent miscarriages can be one of the reasons. Further, a couple who has been through IVF or In Vitro Fertilisation implantation failure a number of times can opt for surrogacy.

How does it Work?
Full surrogacy, as it is known, is a process of implanting an embryo in a host body. This embryo is usually created using the egg and the sperm of the parents, or even a fertilised egg that has been donated by a donor, which is then fertilised using the sperm from the intended father. Also, this embryo may be created by using donor eggs and donor sperms. Partial surrogacy is also a method that may be used. When artificial insemination or intrauterine insemination (IUI) is used to create an embryo with the sperm from the intended father and the egg from the surrogate mother, then the process is known as partial surrogacy.

Chance of having a baby with surrogacy
The chance of having a baby with surrogacy depend on various factors. It depends on the ability of the surrogate to get pregnant, as well as her overall health. Before choosing a surrogate, it is important to put her through all the necessary tests to ascertain a good state of health. Further, the age of the egg donor is also a factor in such cases. The success of related procedures like IVF or IUI will also determine the chances of conception through this method. Furthermore, the quality of the elements used by the couple or the intended parents will also make a difference to the process and its efficacy. Yet, the most important factor includes the age of the woman whose egg is being used.

Difference between IVF and Surrogacy
In IVF, the eggs are gathered from the woman and the sperm is taken from her partner before an embryo is created and affixed in the uterus of the intended mother. In surrogacy, it is actually another woman who carries this lab-created embryo through methods like artificial insemination. The sperm may come from the father and the egg may be donated by someone else, in many cases involving full or partial surrogacy.

What is Surrogacy and how it is different from IVF

In vitro fertilisation (IVF) is a medical procedure followed for those women or couples suffering from infertility or for certain specific genetic problem. In the normal course, women or couples experience positive results within a few IVF cycles. However, in spite of reasonable pregnancy rates, some women may require few more cycles to achieve pregnancy. In such cases, in order to ensure a healthy pregnancy, the gynecologist may suggest the women undergo Endometrial Scratching before IVF. 

Endometrium explained in brief: 

The uterus is located in the pelvic region and it is in the size and shape of a pear. The inner cavity of the womb or uterus is protected by the tissue lining called endometrium, also called endometrial. The endometrium plays a significant role in supporting the pregnancy. 

The enhanced success of achieving pregnancy: 

The endometrial scratching procedure is a very simple one, which is resorted, so as to improve the results of IVF procedure. In this procedure, the gynecologist uses a very fine catheter and makes a small scratch on the endometrial lining. In fact, the scratch causes a kind of inflammatory reaction in the uterus. This inflammatory reaction induces the endometrium to be highly receptive to embryos during the successive menstrual cycle. This added receptivity enhances the success of pregnancy during the next menstrual cycle. 

Considering the higher level of success in achieving pregnancy, the endometrial scratching procedure has gained popularity in the IVF procedure. However, some of the other issues related to endometrial scratching may be as follows: 

Endometrial scratching optimises the uterine lining and thereby, makes it easier to continue the embryo implanting procedure. Normally, before the endometrial scratching procedure, the gynecologist may suggest endometrial biopsy. 
The endometrial procedure is usually suggested for those women who had two or more unsuccessful IVF procedures, despite having good quality embryos. However, in some cases, depending on the health of the patient and various other factors, the gynecologist may suggest this endometrial scratching at the very first IVF procedure. This procedure can be availed either for fresh embryos of the couple or frozen embryos or for the donor egg. 
Although this is a part of a surgical procedure; endometrial scratching is very simple and painless and it is done without administering anesthesia. The procedure does not require any hospitalisation. In fact, the patient can go home soon after the procedure. Except for a few pain killers, this procedure does not require any extensive medication. 
This is a safe and easy procedure. Neither does it lead to any side effects, nor is the procedure burdensome for your wallet. Many couples have been benefited by this endometrial scratching procedure.

Endometrial Scratching and IVF - Can it Help You Get Pregnant?

When we talk about infertility attention usually falls on treatment for women. However, infertility can affect men as well. The condition of infertility, can be described as the inability to become pregnant for a period of 1 year despite having unprotected, well-timed sexual intercourse. A low sperm count is one of the primary reasons for infertility in men.

Typically there should be fifteen million sperm per milliliter of semen. Low sperm count refers to the ejaculation of less than a normal amount of sperm in semen. This can also be termed as oligospermia. A complete absence of sperm in semen is known as azoospermia. Low sperm count does not mean that you cannot impregnate your partner but it reduces the chance of a successful conception. Thus, one of the most common ways to treat infertility caused by low sperm count is IVF.

IVF involves harvesting eggs from the woman s uterus and sperm from the male partner and combining them in a laboratory to form a zygote. When IVF is used to treat male infertility, a semen analysis is the first step. This helps determine the patient s sperm count, sperm motility, volume, pH levels, white blood cell levels etc.
The ejaculated semen is then processed so as to separate the sperm cells from the plasma. In this process sperm cells with higher motility are identified and segregated. These cells have a higher chance of fertilizing the egg.
Sperm cells are then injected into the harvested egg. Some techniques may require the injection of 50,000 or more sperm cells while others such as intracytoplasmic sperm injection (ICSI) can be effective with a single sperm cell. Once the egg is fertilized, it is allowed to develop for a few days in the laboratory. 
Two or three embryos are then selected to be reintroduced into the woman s uterus with the help of a catheter. The remaining fertilized embryos are preserved in an embryo bank in case the pregnancy is not successful. If these need to be used later, the woman does not have to go through the initial stages of IVF treatment to stimulate the follicles and harvest eggs from the ovaries.
When it comes to IVF, the success rates are very high. However, one of the most common side effects is the birth of twins or triplets. This is because multiple embryos are inserted into the uterus. The number of babies born then depends on the number of embryos that are implanted successfully.

Declining Sperm Count - How IVF Can Help Deal With It?

Frozen Embryo Transfer or FET is an extremely effective method to conceive a pregnancy. Recent studies have proved that there is a increased chance for pregnancy when the embryos, which get used are frozen and get placed inside the uterus at a time right after the ovaries are stimulated. Still, certain issues can arise with the transfer of frozen embryo, such as:

A Thin Lining of the Uterus
Research has shown that there are not many women who get pregnant if the lining in their uterine does not tend to thicken enough. It is not clear exactly why this problem occurs in most women and moreover there is no sure shot treatment to make the lining of the uterine thick. The experts on fertility would try out different methods like increasing the amount of estrogen or change the way how estrogen is given. There are other instances when women might be given supplemental medicines, while for some, the problem will continue to exist.

What Should Be Done In Case The Problem Persists?

In case the problem continues for some women, then there are certain approaches which experts might look to adopt. The first one is to cancel the transfer of embryo and try once again at any later stage, that too with a different treatment method.
The second option which they could think of is to go ahead with the transfer, wherein they might feel that a thin lining does not necessarily mean that it is impossible for a woman to get pregnant but definitely the efficiency would be reduced.
One last option is to make use of the opportunity for undergoing additional tests which would help them to assess the ability of the uterus to allow implantation of the embryos.
Unexpected Ovulation
For enabling the embryos to get implanted into uterus, placing them very precisely and at the appropriate time is important. This is regarded as the window of implantation. The time taken, is based on the time frame since progesterone reaches the lining of the uterine.

Doctor knows the exact time to place the embryos, right from the time he or she instructs a woman to start having progesterone supplements. In case a woman was to ovulate, the production of progesterone would begin earlier than the normal time and would lead to the shift of the window of implantation. As identifying the correct time of ovulation is almost impossible, so that would lead to some sort of uncertainty into the timing.

Due to this reason, there are doctors who would use medication in order to prevent unexpected ovulation from occurring. Generally an injection called Lupron is usually used as medication.

Timing for the Embryo Transfer is Inappropriate
This is a problem related to early ovulation. There are case when the implantation window is shifted, still the timing of the transfer becomes accurate. Recent studies have shown that quite a nominal percentage of women might have a window of implantation, which could be either earlier or later than normal time. A test called the Endometrial Receptivity Array can help determine at what time is the window of implantation open.

Frozen Embryo Transfer - Complications Associated With It!

Intracytoplasmic Sperm Injection i.e. ICSI is different from conventional IVF i.e. In Vitro Fertilization because a single sperm is selected by the embryologist to be injected by a needle into the egg rather than a dish with many sperms placed near the egg so that the fastest swimming sperm enters it. Once the sperm is injected directly into the egg, it fertilizes, after which the embryo is transferred into the womb or uterus. 

Your doctor might recommend ICSI treatment for you if you have an extremely low sperm count resulting in infertility or other medical sperm conditions such as poor motility or poor morphology. It may also be suggested if prior attempts at IVF procedures have failed in fertilizing the egg or the fertilization rate is extremely low. You must also consider ICSI treatment if you resort to embryo testing or if the sperm needs to be collected from the epididymis or testicles surgically. 

However, you must keep in mind that if your partner has a genetic problem resulting in low sperm count, it could be passed on to your child, if you decide to use your husband's sperm for this process.

Success Rates of ICSI:
The success rate of ICSI treatment depends on your age and your fertility problem. Your eggs are healthier when you are young and as you age, chances are that they will become less healthy.
1. 35 per cent if you are under 35 years of age
2. 29 per cent if you are between 35 to 37 years of age
3. 21 per cent if you are between 38 to 39 years of age
4. 14 per cent if you are between 40 to 42 years of age
5. 6 per cent if you are between 43 to 44 years of age
6. 5 per cent if you are above 44 years of age

Advantages of ICSI Treatment:
Intracytoplasmic Sperm Injection gives you a chance to conceive a child genetically when most other options are exhausted. Males may be unable to ejaculate on the day the eggs are collected due to anxiety. ICSI proves to be advantageous because sperm may also be surgically extracted for this process. It is extremely helpful for those couples who suffer from unexplained infertility. However, one of the most important factors is that ICSI treatment does not affect your child's physical or mental health.

Intracytoplasmic Sperm Injection (ICSI)

As we all know that IVF stands for In vitro fertilisation. It is a method of stimulating the ovaries in a female body, to release an ovum (egg), which is taken out of the body and fertilised artificially in the laboratory with the help of a sperm. After this, the embryo is transferred back to the uterus where it grows and develops naturally.

Understanding the Procedure

The doctor attempts to have complete control over your menstrual and ovulation cycles, so as to know the correct time of the month when you ovulate. This includes, charting basal body temperatures, hormonal therapy drugs etc.
Frequent blood tests, ultrasound will be required to map the progress of ovulation.
Injections, drugs will be prescribed in required dosage to stimulate the ovaries.
During this time, the doctors will monitor the growth of oocytes (eggs).
After a suitable growth of the oocytes follicles, the eggs are retrieved for artificial insemination. (Fertilisation with the use of sperm cells in the laboratory).
After the successful fertilisation, the embryo is transferred back to the uterus.
Can IVF have side effects?

As a side effect it has a major chance of multiple pregnancies. People intending to have just one child, may not be mentally or economically prepared to take the responsibility of more than one child.
The drugs and medicines used throughout the IVF procedure may create hormonal complications in the long run. It bears a risk of ovarian hyperstimulation syndrome, if the mother has to go through the cycle multiple times.
But it offers a number of benefits too...

IVF increases the chance of pregnancy by a large percentage. It is one of the most successful methods of boosting fertility and pregnancy.
Couples, who have repeatedly failed to bear children naturally, can opt for this treatment to produce their own offspring.
In case the couples are completely infertile, donor eggs or sperms may be used in the process. However, in that case, the offspring will not bear the DNA of both parents.
IVF can greatly reduce the chance of surgery on the fallopian tubes.
IVF also provides an opportunity to choose the healthiest embryos before implanting it back in the uterus. A procedure, known as the pre-implantation genetic diagnosis, determines the presence of any abnormal genes or other chromosomal absurdity.
The procedure of IVF has a very high success rate and with technological advancements in the field of medicine, it has also become much safer.
IVF allows women, who go into premature menopause, to be able to bear a child. This treatment is mostly for women who decide to experience motherhood at a slightly older age.
IVF allows same sex partners and single women to bear an offspring.
It is extremely helpful for women who have their fallopian tubes damaged, blocked or surgically removed.

IVF - 9 Benefits You Must Know!

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