Chromosomal abnormality happens when a cell has too many or too few chromosomes. The most common form of chromosomal anomaly is Down s syndrome. If a parent has a chromosomal anomaly, she/he will pass it on to the child. PGD or Pre-implantation Genetic Testing aims to select only the embryos with normal chromosomal count and only these embryos are implanted to achieve a healthy pregnancy and bring down the number of children affected with a chromosomal anomaly.

The risk of Aneuploid pregnancy:

The older a woman is when she tries to conceive (aged 35 or more), the higher the risk of Aneuploid pregnancy (carrying a baby with genetic or chromosomal abnormality). Most of these pregnancies end in miscarriages and the few that come to term produce babies with chromosomal abnormalities.

Causes of Chromosomal Abnormality:

Usually, chromosomal abnormalities occur due to an error in the cell division. Meiosis refers to the cell division, which the sperm and the egg undergo during the development procedure. Normally, meiosis breaks the chromosomal material into two equal halves, so that each of the parents contributes 23 chromosomes to the pregnancy. However, when the number of chromosomes in the cell goes up or down than the normal, it results in genetic/chromosomal anomalies.

PGD Procedure for a Chromosomal Anomaly:

If a couple elects to go for Pre-implantation Genetic Diagnosis, they have to undergo ICSI Cycle. ICSI cycle initiates a fertilization cycle to produce embryos. When the embryos reach upto day 5 and blastocyst are formed, they are biopsied and further sent to genetic lab for detecting the chromosomal abnormalities. The embryos are incubated for the entire duration of the genetic screening. Only the embryos that the genetic test clears are implanted. PGD never reveals the gender of the embryo.

PGD can help detect the single genetic disorders that may lead to the following ailments:

  Cystic fibrosis
  Muscular dystrophy
  Tay-Sachs
  Sickle cell anaemia
  Thalassemia
  Turner syndrome

PGD is a revolutionary science that can help root out incurable disorders linked to genetics. It ensures that pregnancy is sustained until term and a healthy baby is born.

Suffering From Genetic & Chromosomal Anomalies - Know About PGD!

Smith and Mackie (2007) term self-esteem as a set of positive or negative opinions about oneself. Self-esteem is an important predictor of success in career, relationships, marriage and public life. People who are depressed have a very low self-esteem about themselves. They think of themselves as good for nothings and persons having a nil value. There are three states of self-esteem. They are;

Shattered: An example of a person having shattered self-esteem is when he says,  I am old and useless to do this kind of work . This person sees himself as an absolutely useless person.
Vulnerable: In this state, a slight embarrassment or defeat may expose the vulnerable side of the person. Otherwise, such persons have a positive frame of mind.
Strong: People in this state are very strong emotionally. Defeats, embarrassments etc. do not affect them. These people have a very high sense of self-esteem.
Psychologists, however, have prescribed several ways through which one can improve one s self-esteem.

How to improve one s self-esteem

Control your thoughts- Watch out what your inner critic is saying to you. Every time you hear its voice, ask yourself- would this be the way your best friend would speak to you? If your inner critic is being merciless on you all the time, you need to silence it.
Focus on the good things that happen to you- Everyday, write at least 3 good things that happened to you. Avoid the obstructive or harmful things that came your way. Focus on the happier side of the day. Do not dwell upon the negatives.
No need to be perfect- In the quest to be perfect, many people lose control of themselves. It probably must do with the pressures of modern life where achievement is the be all and end all. But, not everyone can be perfect. Rather, focus on the effort or process. This way, you will be better able to appreciate yourself as a person.
Accept mistakes- Often we fail to realise that mistakes come to us masked as opportunities. But, we are too fixated by the mistakes we commit. We are obsessed with the thought,  Why did I commit this mistake?  rather than,  How to avoid this particular mistake? . If we learn how to avoid committing mistakes, we will tremendously improve our self-esteem.
Experiment with new skills- Try out new skills and then improve upon them. For example, you may pick up music and track your achievement levels. If you continually improve yourself in this new skill, you will obviously set new benchmarks. Give credit to yourself after achievement of every new milestone.
Accept your limits- You are no superman. You have your own limits. Once you accept your limitations, you will stop blaming yourself for all the wrongs that are happening to you. 

Self Esteem - How Can You Improve It?

Anger is among the gamut of emotions we exhibit as a reaction to a situation, and it is a'normal' emotion too as long as it is kept under control. Some people have the propensity to explode when pushed to the extreme. They keep swallowing their emotions until they can finally do it no more, and erupt like a volcano. Others dealing with extreme anger are like a ticking time bomb. You'll never know what you unwittingly say or do can trigger an explosion. In either case, anger that cannot be controlled comes with a physical reaction.

Your heart beats faster preparing you for both action and reaction. Your breathing quickens. You may clench your fist, tighten your shoulders and go into a defensive position. The problem arises out of the fact that it is almost impossible to feel anger and empathy at the same time. An angry person is seldom sensitive to the well being of his victim, and hence may lash out verbally and sometimes physically. Such things done in the heat of the moment mostly leaves us with regrets. So here are a few ways to deal with extreme anger.


	Acknowledge it: the first step in solving a problem is recognizing that you have one. The fundamental problem here is that people believe they are on the right track and refuse to budge from their views. It is essential to realize that this step is not about deciding whether you are right or wrong, but acknowledging the fact that your reaction to the situation can be channeled in a better way. When getting someone to acknowledge their anger problem, be careful as to not use negative words like wrong, false and shouldn't. Instead, influence with positive words like can and should. Instead of saying'you are wrong to react like this, you can say'i understand what you are feeling. Is there a way we can resolve this situation'
	Recognize the signs: once you know that your problems exist, you can try devising ways that will work for you in dealing with the situation. You can count to 10 to calm yourself or simply decide to not speak until you can calm yourself. Knowing that you may enter into an argument in a situation, you can list down the points that you feel strongly about and discuss each of them one by one. Working your way through a finite list gives a better opportunity to reach closure at the end.
	Find ways to let it go: not all arguments end in closure. A lot of unsaid justifications cloud our mind repeatedly leaving us seething from the inside. Research has shown that the neurological anger response lasts less than two seconds. Beyond that it takes a strong will to stay angry. Once you realize how much your anger is consuming your mind, decide to free your mind with meditation and other calming exercises. Tell yourself that some people and issues simply don't deserve your anger, emotion, reaction or time.


If you or someone you know is suffering from anger management issues, consult a doctor today.


How To Control Extreme Anger

Depression is often equated with isolation and brooding but this is not always the case. Many people may actually suffer from depression without showing the typical symptoms of this condition. Hence, this form of depression may go unnoticed for many years. Such cases are known as high-functioning depression. Some of the symptoms of this condition include:

Having difficulty expressing happiness: Though a person may be able to work normally, a person suffering from high-functioning depression will find it difficult to express emotions such as happiness. Thus he or she may not know how to act in the event of a promotion at work, the beginning of a new relationship or any other such happy events. In such cases, the happiness a person experiences from these events is temporary and muted.
Lowered energy levels: Unlike not being able to get out of bed when suffering from typical forms of depression, a person suffering from high-functioning depression can follow his or her usual routine. However, they often find themselves lacking the energy they would normally have and feel the need to put extra effort into their normal tasks. This reduces the amount of satisfaction derived from completing tasks.
Persistent self-doubt: While being self-critical is good to a certain extent, a person suffering from this form of depression is rarely satisfied with their work. Even when recognised by their peers or given an award for their work, they feel that this praise is misguided and have trouble accepting it. Thus, suffering from this condition is akin to swimming a race against the current and with additional unnecessary weights.
Substance abuse: Since this form of depression can go undiagnosed for many years, patients often turn to alcohol and other addictive substances in frustration. This can further delay diagnosis as many of the symptoms of this condition can also be attributed to substance abuse.
Feeling like a failure: Many people suffering from this condition feel as though they are constantly wasting time no matter how much they achieve in a day. This can make them feel hopeless and cause frequent changes in jobs.
The good news is that depression can be cured. Hence if someone around you or you, yourself experience such symptoms, talk to a doctor. Alternatively, you could make a few changes in your lifestyle to lift your mood. Try meditating in the morning or fit in some light exercise into your day. You could even take up a new hobby. However, this cannot replace cognitive therapy and psychological counselling.

High Functioning Depression & Anxiety!

Epilepsy is a relatively common disorder. Most cases of epilepsy can be controlled with a combination of drug therapy and healthy lifestyle. In some cases, surgery may also be advised. Epilepsy affects not only the lifestyle of the patient but also that of their caregiver. Each person reacts to epilepsy in a different way and hence the type of care needed also varies from person to person. While some patients have few seizures and require care only when they're having a seizure others need round the clock care. Here are a few tips to keep in mind if a loved one suffers from epilepsy.

Know what type of epilepsy he/she is dealing with: Not all epileptic seizures are the same. Find out what type of seizures your loved one suffers from and what are the possible triggers associated with Involve yourself in their lifestyle. Epilepsy should not be a reason for your loved one to lock themselves in a room to stay safe. Participate in activities with them of you feel the activity may be a safety risk if they were to have a seizure; for example - swimming.
Notice seizure triggers: Often an epileptic patient may not remember the seizure after it has occurred. As their care giver, keep a seizure diary to track their seizures and its related triggers. Look for patterns in the triggers to their epilepsy attacks.
Keep them safe during a seizure: When experiencing a seizure, the patient will lose consciousness, experience muscle convulsions and may grit his teeth. If the person is standing, hold them so that they do not fall. If they are lying down, try turning them onto their side. Do not put anything into their mouth.
Take care of them after a seizure: After the seizure, people are most likely to be confused, tired and have a headache. Check for injuries and keep them calm till medical help arrives. Loosen clothing around their neck and ensure that there is nothing inhibiting their breathing.
Medical identification: While someone who suffers from seizures often is likely to always have someone with them, others who have rare seizures may often venture out alone. In such cases, ensure that they always have medical identification on them. Also make sure that their friends, colleagues etc are aware of their medical condition.
Help them maintain a healthy lifestyle: Staying active is essential for people with epilepsy. Avoid contact sports and pick low impact exercises like walking, running or swimming. Following a buddy system is essential when an epileptic person works out. If you wish to discuss on any specific problem, you can consult a neurologist and ask a free question.

How to Deal With Epilepsy?

Symptoms for Bipolar disorder varies from patient to patient. Bipolar 1 and bipolar 2 can vary in terms of signs and symptoms. Both diseases have a different set of symptoms and they are diagnosed according to the merit of the symptoms.

Bipolar 1
Bipolar 1 is characterised by a manic episode. This may be followed by a hypomanic or depressive instance. Symptoms of mania can cause major impairment in life and extreme cases may require hospitalisation. Bipolar 1 patients can suffer from psychosis as well.

Bipolar 2
Bipolar 2 is characterised by a hypomanic instance that lasts for at least four days and one depressive instance lasting for a minimum of two weeks. Bipolar 2 doesn t involve a manic episode. Frequent mood swings and violent behaviour can be major challenge in a patient s life.

Warning signs of manic and hypomanic behaviour:
a. Quick passing thoughts
b. Unusual talkativeness
c. Distraction
d. Increased social activity
e. Inflated sense of self-esteem

Symptoms of bipolar disorder

    Anxious distress: Apprehensions about not finishing a task on time, feeling of restlessness, feeling of losing control, difficulty in concentrating due to distress, fearing an awful event will occur in the near future, etc., are key symptoms of anxiety distress.
    Melancholic features: Patients suffering from bipolar disorder like to be left alone. They may not seek pleasure in any activity and even good things may not have much effect on them.
    Catatonia: This is a condition wherein, a person stops reacting to the environment. Not speaking and holding unusual body positions are some signs of these symptoms. There might be a tendency of mimicking too.
    Psychosis: This is one of the classical symptoms of bipolar disease. It is characterised by hallucination, constant depression and delusions.
    Seasonal pattern: There is a pattern of manic, hypomanic and depressive episodes throughout the year. The pattern might change within a month or season.
    Rapid cycling: The number of mood swings can exceed four or more times in a single year.
    Peripartum onset: This is a condition where bipolar disorder symptoms are witnessed in a pregnant woman during pregnancy or within the four weeks following delivery.

Symptoms in children: It is difficult to find symptoms of bipolar disorder in children and teens. Along with bipolar disorder, kids are most often diagnosed with other mental health problems as well. The problems can result from stress, trauma or chemical imbalance of the brain. Perhaps the biggest symptoms of bipolar disorder in children and teens are their frequent mood swings, chronic depression and feeling of despair. There might be a tendency of oversleeping as well. Reaching out to a doctor or professional help is very necessary for cases related to children and teens.

Bipolar Disorder - 7 Signs You Should Be Aware of 

Don't wait any longer, manage your Dyslexia Consultant online with a Lybrate doctor today

Consult for Dyslexia Consultant - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES