Calcium is known for its role in maintaining the bone health, from keeping your teeth stronger to normal functioning of the cells.  But there are various factors, which lead to a deficiency of calcium in the human body and paves the way for several complications.

Here are the top three signs that indicate you are suffering from calcium deficiency.

Difficulty in sleeping: Sleep is essential for your bone health and calcium is directly associated with your sleep cycle. The level of calcium in your bones rises and falls when you are asleep and it reaches its peak when you are in deep slumber. This indicates that when you are unable to sleep properly, it is a warning sign of calcium deficiency. There are various researches that have confirmed, that by increasing the level of calcium, it is possible to restore the normal sleep cycle of an individual. This is also related to the role that calcium plays in the production of a sleep hormone called melatonin. When the calcium content in the body is really low, this hormone is not produced, thus, making it difficult for a person to sleep.
Difficulty in losing extra pounds: Yet another frustrating aspect of any individual s life is the inability to shed off excess pounds. This issue is also linked with the lack of calcium supply in the body. The calcium that s stored in the cells assists in the processing and storage of fat. So the fat cells with high calcium content burn faster, making you lose weight. Thus, if you have trouble losing weight in spite of having a well-regulated diet and regular workout, it s a sign that you are suffering from low calcium.
Paresthesia: Though this ailment is not much heard of, it could be a sign of calcium deficiency. Paresthesia is a nervous disorder, which causes tingling sensation, tremors, numbness and loss of sensitivity. It could also lead to poor concentration, amnesia, confusion, hearing impairment, twitches and other physical as well as neurological impairment. This is because low calcium in the blood is connected with the health of your nerves.
The deficiency of calcium can manifest itself in different intensity, ranging from the non-existent to minimal to severe levels. Chronic calcium deficiency can lead to life-threatening diseases like rickets, osteopenia, and even osteoporosis. Therefore, you shouldn t ignore these signs and consult an expert without delay.

Calcium Deficiency - 3 Signs You are Suffering from it

Most bone fractures mend very easily with proper medical treatment and rest. However, in rare cases, a fracture caused by trauma may not mend even after adequate treatment. When a broken bone fails to heal, it is known as non-union. There are two major reasons for non-union:

  Bone lacks adequate stability

All broken bones require stability to heal. In case of a fracture, doctors place the dislocated bone in its original place and use an external device to hold the broken part in place. Usually, this stability is provided by a splint or cast, but can also be offered by frames and rods as well. However, if the broken bone lacks the required support, it may not set or heal properly, leading to the non-union.

  Fracture lacks proper blood supply

Even with proper stability, a broken bone requires a proper blood supply to start the healing process. The blood carries oxygen and other chemicals that aid in the repair of the bone and makes it crucial during the recovery stage. However, if the blood supply is disrupted, the bone cannot heal and leads to non-union.



Risk factors of non-union:

You are more likely to suffer from non-union if one or more of the following is true in your case-

  People who engage in cigarette smoking and any other form of nicotine addiction have a higher risk of non-unions after a fracture
  Older people can often face non-union, which is why fractures may take longer to heal in these people
  Severe anaemia can often restrict proper blood flow to the broken bone, thus inhibiting the healing procedure
  Similarly, people suffering from diabetes face a greater risk of non-unions
  Lack of proper nutrition may also be blamed for the non-union
  Non-union risks may increase because of side effects from certain medication, such as prednisone, ibuprofen, and aspirin. Consult your doctor in such a case, so that proper precautions can be taken accordingly.

Non-surgical treatment can be used for treating the non-union. Electromagnetic and ultrasound waves are passed through the skin and into the affected bone, in order to treat the non-union. In most cases, this treatment is very effective in curing the fracture. However, if the non-surgical treatment proves ineffective, surgical procedures, such as bone grafts and allograft can be utilized.

Trauma And Nonunion - The Various Risks Involved With It!

Knee is a hinge joint where the lower leg bone tibia meets the thigh bone femur. During osteoarthritis, cartilage or ligament defects and degenerative arthritis, knee replacement surgery is recommended world-wide to get relief from extreme pain. Knee replacement surgery, also known as knee arthroscopy, is a surgical procedure, in which the affected knee joint is replaced with synthetic material. The most likely candidates for total knee replacement are the patients with severe destruction of the knee joint coupled with progressive pain and impaired function.

Modern technological advances have made computer assisted knee replacement surgery extremely popular around the globe. In this surgery, the surgeon is assisted by a computer to remove the optimum amount and angle of the bone, which otherwise is done by inspecting manually. This is an excellent example of surgery through small incision and it eliminates the chances of human error. A perfect alignment and balance is achieved and hence longevity is also increased to 20 - 30 years. Knee replacement surgery is also specific to gender as the anatomy of male and female patients is different.

There are many types of knee replacements, most common being the total knee replacement or Total Knee Arthroplasty. In addition, there is partial knee replacement, bilateral knee replacement, revision knee replacement and knee arthroscopy.

In knee replacement surgery, the worn out surfaces of joints of knee are replaced with artificial implant of plastic and metal. The lower end of the femur bone is removed and replaced with a metal shell. The upper end of the lower leg bone (tibia) is also removed and replaced with a channelled plastic implant with a metal stem. A plastic ball is also added under the kneecap depending on its condition. These artificial components are commonly referred as prosthesis. The design of these highly flexible implants replicate knee, with the rotating knee replacement implants assist in backward and forward swing of the legs.

Patients whose knee joints have been damaged by either trauma or progressive arthritis should consider total knee replacement surgery. Post-surgical hospital stay after knee joint replacement is usually three to five days. The surgery has a very high success rate and shows dramatic improvement after a month. This improvement is most notable one month or more after surgery. The pain caused by the damaged joint is reduced significantly when the new gliding surface is constructed during surgery. Initially, patient will walk with the help of a walking aid until the knee is able to support full body weight. After six weeks, patient can walk comfortably with minimal assistance. Patients with artificial joints are prescribed to take antibiotics during the course of any elective invasive procedures including dental work. Physiotherapy is an essential part of rehabilitation and it will increase the muscle strength and patient can enjoy most activities, except running and jumping.

Knee Replacement

There are 27 bones in the human hand. An injury to any one of them or a disease that affects the bones, tendons, muscles or blood vessels in the hand, are the most likely causes for pain in the hand and tenderness.

Some of the most common conditions that cause hand pain are:

De Quervain's Tendinitis: Pain on and around the thumb is the characteristic sign of this condition. This pain may develop gradually or come on suddenly and can travel the length of the thumb and forearm. De Quervain's tendinitis is caused by the swelling of wrist tendons at the base of the thumb. Repetitive actions and overuse are the most common triggers for this condition.

Carpal Tunnel Syndrome: The symptoms of carpal tunnel syndrome are felt mainly in the thumb, index finger and middle finger. This pain is often worse at night and is caused by the swelling of inflamed tendons at the base of the hand that puts pressure on the median nerve. This syndrome can make it very difficult for a person to grip objects.

Fractures: The fracture can cause extreme pain along with stiffness, swelling and loss of movement. A fracture refers to the breaking of a bone and can be of many types including simple fractures, complex fractures, comminuted fractures and compound fractures. The type of fracture dictates the type of treatment required. Spraining a muscle in the hand is another leading cause of pain in the hands.

Arthritis: This is one of the most common causes of pain in the hand that is related to ageing. Arthritis causes loss of cartilage that makes the movement of one bone against the other extremely painful. It may or may not also be accompanied by swelling. When it comes to the hand, arthritis affects the base of the thumb and middle or top joints of the fingers. Osteoarthritis may also cause bony nodules to be formed on the fingers.

Trigger Finger: This condition is also known as stenosing tenosynovitis. This condition locks the fingers or thumb in a bent position. This condition is triggered by the flexor tendons getting irritated. These tendons control the movements of the thumb and fingers. As the tendon is inflamed, the sheath that surrounds the tendons may also thicken and nodules may form of the affected tendons. People suffering from rheumatoid arthritis, gout and diabetes are at a high risk of suffering from this condition.

Pain And Tenderness In Bones Of The Hand - Factors That May Cause it!

When there is a fracture of the bone, the affected site may be plastered for the fracture to heal. In some cases, this may not be enough to mend the bones and surgery may be required along with bone grafting to rectify the condition. A new form of therapy, involving a less invasive procedure has been developed. It involves culturing the stem cells and using the same to mend and regenerate parts of the bone.

What does the treatment involve?

In this process, one cultures cells from the patient s body. The cells are extracted from the bone marrow. These cells are cultured in the lab and injected back to the affected region of the body. Research has shown that after the injection, the treatment takes anywhere between 7 to 8 weeks to repair the fracture completely.

Since stem cells are being harvested from the patient and not from a third-party, the treatment does not have any ethical constraints. However, more studies are being conducted to prove without a doubt that the same does not cause any damage to the body of the patient in the long run.



It is likely that this procedure will replace rudimentary surgical techniques, such as bone harvesting, in the future. It is far less invasive and does not result in extreme pain or prolonged hospitalization.

The future of the treatment: 

While stem cell culture has been around for a few years now, the use of the same procedure to treat fractures is The Latest Technology. It is in its early stages, which is why such a form of treatment is not offered by all hospitals across the globe and very selective surgeons having experience of the procedure would perform it.

Additional research and studies are being conducted to further confirm the efficacy of the treatment. Research has revealed that stem cell insertion in the bone can be used to regrow defects and heal non-unions of a bone. In some cases, repeated stem cell insertion may be required. The bone that grows as a result is as strong as the other bones in the body.

Stem Cell Culture For Broken Bones - What Is It?

Knee replacement can be extremely painful. Previously, opioids or narcotics were administered for pain relief. But excessive addition of opioids is not exactly effective for controlling pain. 

Multimodal pain management has become an important part of the perioperative care of patients undergoing total joint replacement. The principle of multimodal therapy is to use interventions that target several different steps of the pain pathway, allowing more effective pain control with fewer side effects. Many different protocols have shown clinical benefit. The goal of this review is to provide a concise overview of the principles and results of multimodal pain management regimens as a practical guide for the management of joint arthroplasty patients.

Multimodal denotes administering two or more than two types of medications that work with different mechanisms. The following are the techniques used:

Pre-operative Femoral Nerve Block: Prior to the surgery, a catheter is placed beside the femoral nerve for blocking it. This nerve is located in the upper thigh. Medication is delivered through the catheter for the nerve to be numbed for 24 hours. Thus, pain signals to the brain are blocked. This method reduces the use of narcotics and the consequent side effects.

Patient Controlled Analgesia (PCA): This method is also known as  Pain Pump . An intravenous pump is used to administer pain relief medications, such as oxymorphone or morphine, after the surgery. The control button of the machine could be pressed, by the patient for 6 to 10 times per hour. The machine is used for two post-operative days.

Oral Medications: The oral medications include Non-Steroidal Anti-Inflammatory drugs or NSAID; such as Celebrex which is similar to aspirin, structurally. Alternatively, acetaminophen, such as Tylenol or its equivalent composition, can also be used.

Acetaminophen: It acts on the Central Prostaglandin Synthesis and relieves the patient of pain through multiple mechanisms.

Epidural Analgesia: It produces lower pain scores and involves less time for achieving physical therapy goals. However, this is subject to side effects such as dizziness, urinary retention and itchiness.

Gabapentinoids: These medications include membrane stabilizers such as Gabapentin and Pregabalin.

The objective of multimodal treatments is to provide quick relief to the patient and immediately so. Earlier the rehabilitation, more successful will be the knee replacement surgery.

Multimodal Pain Relief After Total Knee Replacement

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