When there is a fracture of the bone, the affected site may be plastered for the fracture to heal. In some cases, this may not be enough to mend the bones and surgery may be required along with bone grafting to rectify the condition. A new form of therapy, involving a less invasive procedure has been developed. It involves culturing the stem cells and using the same to mend and regenerate parts of the bone.

What does the treatment involve?

In this process, one cultures cells from the patient s body. The cells are extracted from the bone marrow. These cells are cultured in the lab and injected back to the affected region of the body. Research has shown that after the injection, the treatment takes anywhere between 7 to 8 weeks to repair the fracture completely.

Since stem cells are being harvested from the patient and not from a third-party, the treatment does not have any ethical constraints. However, more studies are being conducted to prove without a doubt that the same does not cause any damage to the body of the patient in the long run.



It is likely that this procedure will replace rudimentary surgical techniques, such as bone harvesting, in the future. It is far less invasive and does not result in extreme pain or prolonged hospitalization.

The future of the treatment: 

While stem cell culture has been around for a few years now, the use of the same procedure to treat fractures is The Latest Technology. It is in its early stages, which is why such a form of treatment is not offered by all hospitals across the globe and very selective surgeons having experience of the procedure would perform it.

Additional research and studies are being conducted to further confirm the efficacy of the treatment. Research has revealed that stem cell insertion in the bone can be used to regrow defects and heal non-unions of a bone. In some cases, repeated stem cell insertion may be required. The bone that grows as a result is as strong as the other bones in the body.

Stem Cell Culture For Broken Bones - What Is It?

Most bone fractures mend very easily with proper medical treatment and rest. However, in rare cases, a fracture caused by trauma may not mend even after adequate treatment. When a broken bone fails to heal, it is known as non-union. There are two major reasons for non-union:

  Bone lacks adequate stability

All broken bones require stability to heal. In case of a fracture, doctors place the dislocated bone in its original place and use an external device to hold the broken part in place. Usually, this stability is provided by a splint or cast, but can also be offered by frames and rods as well. However, if the broken bone lacks the required support, it may not set or heal properly, leading to the non-union.

  Fracture lacks proper blood supply

Even with proper stability, a broken bone requires a proper blood supply to start the healing process. The blood carries oxygen and other chemicals that aid in the repair of the bone and makes it crucial during the recovery stage. However, if the blood supply is disrupted, the bone cannot heal and leads to non-union.



Risk factors of non-union:

You are more likely to suffer from non-union if one or more of the following is true in your case-

  People who engage in cigarette smoking and any other form of nicotine addiction have a higher risk of non-unions after a fracture
  Older people can often face non-union, which is why fractures may take longer to heal in these people
  Severe anaemia can often restrict proper blood flow to the broken bone, thus inhibiting the healing procedure
  Similarly, people suffering from diabetes face a greater risk of non-unions
  Lack of proper nutrition may also be blamed for the non-union
  Non-union risks may increase because of side effects from certain medication, such as prednisone, ibuprofen, and aspirin. Consult your doctor in such a case, so that proper precautions can be taken accordingly.

Non-surgical treatment can be used for treating the non-union. Electromagnetic and ultrasound waves are passed through the skin and into the affected bone, in order to treat the non-union. In most cases, this treatment is very effective in curing the fracture. However, if the non-surgical treatment proves ineffective, surgical procedures, such as bone grafts and allograft can be utilized.

Trauma And Nonunion - The Various Risks Involved With It!

Knee pain: causes and tips to manage knee pain

The knee is the largest joint of the body and is made up of upper and lower bones that are separated by two discs known as menisci. While minor knee pain may be experienced by many people, it should be handled with medical intervention when it becomes a serious and debilitating problem. Sudden injury or injury due to overuse as well as myriad conditions that affect the joints and muscles can bring about knee pain. Underlying conditions like osteoporosis or arthritis, which affect the bones and joints, can also cause knee pain. The symptoms include painful swelling and stiffness as well as severe discomfort. Let us learn more about the causes of knee pain and the ways in which it can be managed-

Injury: exercise and sports injuries are one of the most common causes that can be the start of acute knee pain, as well as chronic condition. These kinds of injuries can affect the ligaments and cartilage which leads to severe pain. The pain can even affect the way one functions in one's daily life. Knee ligament injuries can also cause this kind of pain. These ligaments are bands of tissues that connect the thigh bone with the lower leg bones. Sprains and tears in the acl or pcl are common in sports injuries, and may even require surgery in many cases. Knee cartilage tears can also take place in the hard yet flexible cartilage of the knee which can affect the meniscus around the knee. This condition may also require surgery.

Arthritis: this condition can affect the knees specifically and is one of the most common types of arthritis. This is a chronic condition which gets progressively worse over time and may even require surgery. Stiffness and inflammation are common symptoms. Rheumatoid arthritis is also a degenerative auto-immune disease that can affect the knees and cause knee pain. Furthermore, post traumatic arthritis can also be experienced after an injury. Osteoarthritis is another common condition that leads to knee pain. It basically occurs due to wear and tear of the knees over a prolonged period and is usually experienced by patients over the age of 50.

Managing knee pain: while pain medication and anti-inflammatory drugs may be prescribed for most cases, along with surgery in the long run, it is also possible to manage knee pain with the help of better lifestyle choices like regular knee and muscle strengthening exercises as well as rest - rest, ice, compression and elevation. These methods can help in relieving inflammation and pain. But very severe cases will require medical intervention, so it is imperative to get in touch with your doctor if the condition does not improve.

Knee Pain: Causes and Tips to Manage Knee Pain

Knee replacement can be extremely painful. Previously, opioids or narcotics were administered for pain relief. But excessive addition of opioids is not exactly effective for controlling pain. 

Multimodal pain management has become an important part of the perioperative care of patients undergoing total joint replacement. The principle of multimodal therapy is to use interventions that target several different steps of the pain pathway, allowing more effective pain control with fewer side effects. Many different protocols have shown clinical benefit. The goal of this review is to provide a concise overview of the principles and results of multimodal pain management regimens as a practical guide for the management of joint arthroplasty patients.

Multimodal denotes administering two or more than two types of medications that work with different mechanisms. The following are the techniques used:

Pre-operative Femoral Nerve Block: Prior to the surgery, a catheter is placed beside the femoral nerve for blocking it. This nerve is located in the upper thigh. Medication is delivered through the catheter for the nerve to be numbed for 24 hours. Thus, pain signals to the brain are blocked. This method reduces the use of narcotics and the consequent side effects.

Patient Controlled Analgesia (PCA): This method is also known as  Pain Pump . An intravenous pump is used to administer pain relief medications, such as oxymorphone or morphine, after the surgery. The control button of the machine could be pressed, by the patient for 6 to 10 times per hour. The machine is used for two post-operative days.

Oral Medications: The oral medications include Non-Steroidal Anti-Inflammatory drugs or NSAID; such as Celebrex which is similar to aspirin, structurally. Alternatively, acetaminophen, such as Tylenol or its equivalent composition, can also be used.

Acetaminophen: It acts on the Central Prostaglandin Synthesis and relieves the patient of pain through multiple mechanisms.

Epidural Analgesia: It produces lower pain scores and involves less time for achieving physical therapy goals. However, this is subject to side effects such as dizziness, urinary retention and itchiness.

Gabapentinoids: These medications include membrane stabilizers such as Gabapentin and Pregabalin.

The objective of multimodal treatments is to provide quick relief to the patient and immediately so. Earlier the rehabilitation, more successful will be the knee replacement surgery.

Multimodal Pain Relief After Total Knee Replacement

Causes and symptoms of knee pain

Knee pain is characterized by a feeling of pain in the knee joint caused by injury or overuse. The knee joint consists of small bone structures, the kneecap, supporting ligaments and cartilage of the knee. This joint bears the full weight of the body, which makes it very vulnerable to injury.

Causes of knee pain

Knee pain is usually caused by injuries to the knee such as exposure to a direct force on the knee, abnormal twisting of the knee or falling on your knees. Some causes of knee pain are -

Knee strains and sprains - Overworking the knee joints can damage the tissues of the knee joint resulting in knee sprains and strains

Osteoarthritis - it is condition where the protective cartilage around the kneecap is damaged, resulting in knee pain

Bursitis - Excessive movement of the knee or kneeling down for extended periods can irritate the bursa (a fluid sac below the skin above the knee joint) that causes swelling and pain, thereby giving rise to this condition

Gout - This condition is characterized by the accumulation of uric acid in crystal form around the knee joint, causing inflammation and pain

Tendon disorders - Tendons connect the muscles to the bones, and overworking the knee can cause the tendons around the knee to become sore and painful

Kneecap dislocation - Injuries may cause the kneecap to shift out of its position, this causes swelling and pain in the knee joint

Symptoms of knee pain

Severe knee pain can restrict movements such as walking or standing. The symptoms vary according to the extent of the damage suffered by the knee. Most common symptoms of knee pain are problems in climbing stairs, inability to extend the knees, limping and swelling of the knee joint. In some cases, knee pain may also cause fever.

Causes and Symptoms of Knee Pain

The spine or the backbone is responsible for the fluid movement of the body, especially standing, bending, and sideways movement. It also is an important part of the nervous system and carries multiple nerves to the lower part of the body. The lower spine has sacral and iliac vertebrae, which have disks between the vertebral bones where these nerves are located. With age, infection, tumors, or injury, this soft tissue becomes hardened and get the bones to fuse. This is a type of arthritis known as ankylosing spondylitis and limits movement between the disks.

Causes: With age, the soft vertebral tissue gradually hardens. There is a genetic component also to this, so it runs in families. In addition, infection or tumors of the spine and injuries involving the spine can also lead to this condition.

Symptoms: When AS ankylosing spondylitis (AS) onsets, there is usually morning pain and stiffness in the low back and upper buttocks. The intensity of this gradually reduces over the course of the day. The range of movement also is reduced, with bending, stooping, and sideward movement becoming gradually difficult. It is believed that people with AS have an overactive immune system, and homeopathy helps by suppressing this activity. A homeopath will have a detailed discussion with the patient and based on the presenting symptoms, an appropriate product would be prescribed.

Aesculus: The patient would have extremely painful and stiff low back and hips. It would be constant ache with walking and stooping, and it is not easy to rise from a sitting position. The patient also feels that the legs would give way, making them hesitant to walk.
Rhus Tox: When the patient presents with low back pain that is present at rest, with sitting and inactivity, Rhus is usually preferred. The pain improves with activity and movement and radiates down the legs all the way to the foot.
Kali Carb: If the patient presents with extreme weakness also and feels like a paralytic attack, as if the back is broken. The patient feels the symptoms are worse in the morning and changing position in bed.
Kalmia: If the patient has pain associated with a prickly, numbing sensation, then this is used. There also could be burning sensation. The pain appears in bursts in the late evening and early night hours and could also go down the legs or up into the neck.
As with any other disease, homeopathy looks at the person holistically and treats the symptoms. The patient should not go for self-medication based on some reading and friends suggestions. Each person is unique in terms of symptoms and treatment, and so the doctor is the best person to decide the appropriate medicine.

Homeopathy Treatment For Ankylosing Spondylitis!

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