Most people believe kidneys to be organs solely responsible for the filtration of blood and production of urine. But the truth is that the kidneys perform a host of vital functions in the body which include regulation of blood pressure, blood volume, and blood Ph. Around half of the individuals affected by lupus suffer from kidney problems, and the most affected part is the glomerulus whose function is filtering substances from the blood.

Effects of lupus nephritis on the kidneys
Lupus itself doesn t lead to kidney infection or inflammation. But lupus nephritis, which is the Systemic lupus erythematosus (SLE) that affects the kidneys and the medications used for treating the condition tend to suppress the immune system. It makes the person affected with lupus vulnerable to the infections of various types. It is one of the most severe conditions of that could be encountered by a person wherein the immune system starts attacking various parts of the body as they would tackle a disease.

Lupus nephritis makes the kidney unable to remove the waste materials effectively from the blood. This leads to loss of control over the amounts of fluids regulating in the body. As a result, an abnormal amount of waste can build up in the blood resulting in edema or swelling.

When left untreated, these conditions can cause scarring along with permanent damage to the kidneys and end-stage renal disease. When a person has end stage renal disease, he or she needs regular filtering of the waste products of the body with the help of a machine. In severe cases, a kidney transplant may be required to ensure that at least one kidney is working properly.

Individuals who are susceptible to developing lupus nephritis:
A person with lupus may see the symptoms of lupus nephritis within 5 years and the people aged between 20 and 40 years are most vulnerable to it. In some common instances, it is seen that lupus nephritis is leading to unexplained weight gain along with swelling and puffiness in different parts of the body such as ankles, hands, eyelids, legs, and feet. During the first stages, these symptoms are often ignored which causes worsening of the condition. The urine may also become frothy or foamy with a reddish tinge in it. It is estimated that about 40 percent of children having lupus would develop kidney complications. Lupus nephritis may also cause increased urination, blood in the urine and elevated blood pressure.

If you have lupus, it is imperative to consult with a nephrologist. Testing a sample of the urine can help in showing the problems in the functioning of the kidneys. Your doctor will advise you about the diagnostic tests that can help in determining whether the disease has progressed to severe levels and start with the treatment process accordingly.

How Does Lupus Nephritis Affect Your Kidneys?

3 Causes of Acute Kidney Failure

You're said to suffer from the problem of acute kidney failure if your kidneys suddenly stop working and lose their ability to eliminate waste materials including excess fluids and salts from the blood. The condition usually develops quickly over a few days or even a few hours. When this happens, waste materials accumulate in your blood, disrupting the chemical balance of your bloodstream.

So, what causes this problem?

Acute kidney failure can occur because of any one of these reasons:

1. A drop or slowdown of blood flow to the kidneys - Adequate blood circulation to the kidneys is of great importance as without it the kidneys may end malfunctioning. If blood flow to the kidney is hampered, a part of or the entire kidney may die. You may suffer from acute kidney failure if blood flow to the kidneys gets impaired due to conditions like

-Heavy blood loss
-Sepsis (body's inflammatory reaction to an infection, which can bring about organ failure, tissue damage, and death)
-Injury
-Use of certain drugs
-Dehydration
-Burns
-Heart disease

2. Urinary obstructions - A sudden blockage that hampers your kidney's ability to eliminate urine can also bring about acute kidney failure. When this happens, it leads to a build up of toxins in the body, causing an overload of the kidneys. Conditions that bring about this urinary obstruction include:

-Cervical cancer
-Colon cancer
-Bladder cancer
-Kidney stones
-Enlarged prostate
-Prostate cancer

3. Disease within the kidneys - Even instances of clotting within the blood vessels of the kidneys can lead to acute kidney failure. This is because if the movement of blood cells within the blood vessels gets hampered, kidneys are not able to filter out toxins from the body. The conditions and diseases that may cause clotting, and subsequently damage to the kidneys include:

-Scleroderma (an autoimmune disease that affects connective tissues and skin)
-Build-up of cholesterol deposits
-Glomerulonephritis (an inflammatory condition of the kidney's ball-shaped structures called glomeruli)
-Hemolytic uremic syndrome (a condition that occurs due to untimely death of red blood cells)
-Lupus (a disorder of the body's immune system that brings about damage to the body's own organs and tissues)



3 Causes of Acute Kidney Failure

Causes and symptoms of acute tubular necrosis

Damage or destruction to tube-like structures known as tubules in the kidneys can bring about the development of acute tubular necrosis (ATN) and subsequently, acute kidney failure.

What causes acute tubular necrosis (ATN)?

A lack of supply of oxygen to the cells in the kidney is the most common cause of this condition. The reason as to why oxygen may not reach the cells and tissues of this organ could be restriction or blockage of the pathways. When this happens, the kidneys get damaged. Dehydration is the most important cause of ATN which may be because of loose motions, vomitings, heat stroke etc.

Health conditions such as diabetes, heart attack, and stroke can bring about a decrease in blood flow to the organs resulting in ATN and death of cells. Similarly, the presence of toxic substances in the blood can also lead to tubules damage and change the way the cells function in the tubules.

Other causes that may lead you to develop ATN may be medications, radiology dyes, anesthetics and chemicals that cause your body to react adversely.

In addition to these causes, a number of factors can put you at risk of ATN and there are:

- An injury to the body, more specifically your kidneys can cause clotting of the blood vessels
- An adverse response to blood transfusion
- Instances of septic shock can slow down blood flow to the organs
- A major surgery that can interrupt blood supply to the organs

What are the symptoms of the condition?

The symptoms associated with the condition can vary depending on the severity of the problem.

You may experience:

- Troubles in waking up
- Drowsy feeling even during daytime
- Feelings of lethargy
- Feelings of excessive thirstiness
- Problems with urination
- Fluid retention problems
- Instances of confusion
- Feelings of nausea



Can Acute Tubular Necrosis Cause Kidney Failure?

Kidney is the most vital organ in the body as it eliminates the waste material from our blood. When kidneys fails to carry out its work effectively the waste materials gets accumulated in the blood and end up with many serious disease condition that affects the other vital structures in our body. The function of the kidney is carried out artificially by an external device called dialyser to purify the blood and remove the waste products from it. This procedure is called as dialysis. There are two types of dialysis they are haemodialysis and peritoneal dialysis. In Haemodialysis, the waste products are removed from the blood and there by the fluid and electrolyte balance is maintained.

Things a person should follow if they are undergoing haemodialysis

Love your heart: Patients undergoing dialysis are at more risk of getting cardiac problems. So it is best advised to follow few of the following measures to take care of their heart
Keep your blood pressure and cholesterol levels under control
Quit smoking
Reduce stress
Have healthy low fat and heart friendly diet
Get regular physical activity but avoid excessive strainers activity that may require extra effort from your heart
Maintain a healthy weight
Diet: Dialysis not only removes the waste matters from your blood but sometimes also the essential electrolytes and nutrients. Protein, potassium sodium and phosphorus are the major things that are to be noted.
Encourage the patient to take high quality protein rich foods like meat, fish, milk, egg and chicken which is essential to improve your muscle strength and immunity.
Have a check of your sodium level and take sodium rich foods accordingly, as excess sodium may increase the fluid intake.
Limit your fluid intake: Use ice cubes instead of water or use small cups of water. Make sure you measure every sip of water you take.
Don't Overeat: Slow down while eating and stop eating when you feel full. don t over load your stomach

Haemodialysis - 4 Things a Person Must Follow if Your Undergoing it

There can be no better way to maintain a healthy lifestyle other than a regular exercise and fitness routine. Sometimes even after surgeries, doctors recommend exercise to the patients for a speedy recovery. A kidney transplant is one such surgery that requires you to follow a strict fitness regime after the operation process.

Importance of Exercise after a Kidney Transplant:

Exercise, as recommended by the doctor, should be an integral part of the lives of kidney transplant patients. The variations of exercise may differ depending on the age and general physical health of the patient. The need for exercise after a transplant is as follows  

  Helps to increase energy levels
  Increases overall physical strength and immunity
  Helps maintain a standard weight as an obese body is very harmful for patients suffering from kidney ailments
  Reduces stress, anxiety and depression
  Prevents after effects of kidney transplant like high blood pressure and cholesterol level
  Helps to strengthen bones
  Helps tone muscles and increases balance and joint flexibility
  Strengthens the heart and overall cardiovascular system
  Helps the patient to sleep better
  Boosts self-image and increases confidence

Types of Exercises that can be done:

  Stretching   Consistent stretching before any exercise helps increase muscle strength. It also prevents muscle strain and injury.
  Aerobic   Aerobic or cardiovascular exercises are generally recommended for younger patients. It includes moderately heavy exercises involving a greater number of muscles. This kind of exercise strengthens the heart and lungs and improves breathing. Aerobic exercises include walking, jogging, jumping rope, bicycling, skating, rowing and water aerobics. However, for most patients, brisk walking or jogging is recommended.
Ideally one should exercise for a minimum period of 20 minutes at least four times a week.

Things to Remember:

  It has been medically proved that patients who exercise regularly following a kidney transplant procedure are more likely to survive healthily for the upcoming 5 years compared to patients who lead a sedentary life.
  However one should not resort to heavy and strenuous exercises immediately after the surgery. It is advisable to start with mild forms of exercise like walking and increase the levels gradually depending on one s age.
  One should not eat a heavy meal just before exercising.
  It is important to stop for breaks in between exercise. The patient should not over exert himself.
  It is advisable to avoid lifting heavy weights like dumbbells.
  Stop exercising immediately if you experience chest pain, lightheadedness or pressure in chest, neck or arm.
  Consult the doctor for the kinds of exercises you can do depending on your condition.

With a healthy diet and regular exercise, there are fewer chances of reoccurrence of kidney ailments.

Fitness/Exercise/Games After Kidney Transplant!

If your doctor ever diagnoses you with chronic kidney disease, he/she will give you two options to choose from. The first option is to undergo dialysis for the rest of your life, while the other option is to undergo a kidney transplant. While you may prefer avoiding a major surgery, such as a transplant, dialysis is not the best solution for your condition.

Here are some reasons why you should consider kidney transplant surgery over dialysis if you are looking for better health for the long-term:

1. Increases your life expectancy: What you may not know is that people on dialysis treatment have a severely reduced life expectancy. For instance, if you are 30 years old when dialysis starts, the treatment will keep you alive at most for 15 more years. Therefore, you may not even survive until your fifties with dialysis treatment for your damaged kidneys.

However, if you transplant a healthy kidney your life expectancy increases by 30 to 40 years. Keep in mind that kidneys from living donors are better and will help you live longer.

2. Eliminates the need for undergoing dialysis: If you choose dialysis over transplant surgery, you will need to undergo the treatment on a daily basis. This is not only costly but also affects your quality of life. For instance, a patient on dialysis will need to make special arrangements if he/she wants to go on a vacation with family so that his treatment continues even during the trip.

With a kidney transplant surgery, once you recover from the operation, you can live a normal life, without the need for daily treatment.

3. Lower cost of treatment: While you may think kidney transplant surgery is the costlier option between it and dialysis, you would be wrong to assume so. In kidney transplantation surgery, you pay a hefty amount at the time of the operation. However, in the case of dialysis, you pay smaller sums over very long periods. When you add up these small sums over 10-15 years of dialysis, you will find that transplantation is the cheaper option.

If you are young and have a long life ahead of you, kidney transplantation should be the first and foremost choice of treatment for chronic kidney disease. You can undergo dialysis while you wait for a donor and then receive a healthy organ.

Why Kidney Transplant Should Be Preferred Over Dialysis?

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