Urinary tract infections (uti) can occur anywhere in the urinary system   the bladder, kidneys, urethra, and ureter. Most of these infections affect the lower part of the urinary system   urethra and the bladder.

An infection ;confined to the bladder can be frustrating and painful. You may experience pain during urination, and pus or blood in the urine. However, the condition becomes worse if the infection spreads to the upper part of the urinary system, particularly to the kidneys, triggering nausea, ;vomiting, and severe pain in the back.

If uti is left untreated, it can potentially lead to kidney damage   a condition known as pyelonephritis.

How does untreated uti affect the kidneys?

Untreated urinary tract infections can cause the kidneys to swell up and damage them permanently. The infections initially begin in the lower tract of your urinary system. Then the bacteria slowly enter your body through the urethra and begin multiplying and spreading up to the bladder. The bacteria eventually travel to your kidneys through the ureters.

Some people are at higher risk for kidney damage due to urinary tract infections. This includes  


	
	Pregnant women
	
	
	Elderly people
	
	
	People with kidney problems
	
	
	Someone with a weak immune system
	


Signs to watch out for

An untreated infection in the bladder that has spread to the kidneys is associated with symptoms, such as the following  


	
	Chills and ;fever
	
	
	Vomiting and nausea
	
	
	Pain in either side of your lower back
	


You should visit a doctor right away if you notice the above uti symptoms. The condition requires immediate medical intervention in order to prevent damage to your kidneys.

Symptoms of painful utis can be managed by combining medications and lifestyle remedies. Consult a specialist to diagnose the condition early and seek appropriate treatment to avoid complications.

Untreated Urinary Tract Infections And Kidney Damage: Know The Connection

Cushing syndrome occurs due to prolonged exposure to high levels of cortisol hormone. The condition, often referred to as hypercortisolism, affects women   usually between ages 25 and 40   more than men. Nearly 80% of adults and about 47% of children are diagnosed with cushing syndrome.

The most common cause of cushing syndrome is an overproduction of the stress hormone   cortisol   by the adrenal glands. However, it can also result from overuse of steroid drugs.

If you have cushing syndrome, you are likely to notice symptoms like muscle weakness, weight gain, a buffalo lump, irregular periods, sleep disorders, high blood glucose and high blood pressure.

Recent research has claimed to establish a relation between cushing syndrome and high blood pressure   or what is called hypertension in medical terms.

The link between hypertension and cushing syndrome

Hypertension refers to high blood pressure that causes the force of blood to raise against the artery walls. A number of conditions can lead to hypertension, such as poor diet and lifestyle, an underlying health issue, stress, pregnancy and so on.

As your body encounters stress, the adrenal glands produce and release cortisol in the bloodstream. Studies show that producing excess stress hormone can create a host of pathological problems in the body, including hypertension.

Hypertension is a distinguishing feature of endogenous cushing syndrome. High blood pressure in cushing syndrome has a significant correlation with the duration of hypercortisolism and results from the interaction between various pathophysiological methods regulating peripheral vascular resistance, cardiac output, and plasma volume   all of which are elevated in this state.

How to treat the condition

Cushing syndrome is usually treatable and curable. You will be prescribed to stop using steroid drugs that are likely to increase cortisol levels. If the condition does not improve after treatment, you will have to look for ways to manage the symptoms, especially by monitoring your blood pressure. Team up with your doctor and ask for ways to de-stress yourself.

Relation Between Cushing Syndrome And Hypertension: Know More

People suffering from sickle cell disease (scd) usually start showing symptoms very early. They can appear to show up even during the first year of life. Symptoms of a sickle cell vary from one person to another and can be mild to serious depending on the condition.

 

Sickle cell disease is a health condition that worsens with time. Despite the absence of any full-proof solution, some treatments prevent further complications. These treatments can help patients receive aid for a lifetime. Simply said, sickle cell diseases can be managed medically.

 ;

Treatment

Treatment in a sickle cell patient depends on the severity of the symptoms. Preventing complications and relieving pain is the primary aim of the diagnosis. They can range from medications to blood transfusions.

 

Concerns

Some of the concerns that need to be taken care of during the treatment of scd are-

 ;


	
	Prevent painful scenarios
	


A painful episode or sickle cell crisis can be avoided by consuming sufficient fluids, wearing warm clothing, and staying away from sudden temperature changes.

 


	
	Avoid infections
	


Children with sickle cell anemia are made safe from infections by using penicillin. Adults with anemia might need to take penicillin all their lives. Doctors should ensure that all vaccinations in children and adults are periodically done to avoid any infections. However, during the covid-19 pandemic sickle cell patients should take extra care.

 ;

Medications

While there can be numerous ways to manage sickle cell treatment, medications help in a significant way. Some of the prescribed medicines are-


	
	Hydroxyurea- it reduces the frequency of sickle crises. Pregnant women should stay away from this according to experts.
	
	
	Crizanlizumab- this drug injected into the patient can help reduce the sickle crises in adults and children over the age of 16.
	
	
	Voxelotor- it is an oral drug used in children over 12. It lowers the risk of anemia by improving blood flow.
	
	
	Pain-relievers- narcotics to prevent excessive pain can also be used during the treatment.
	


 

Surgical procedures


	
	Blood transfusion
	


It is used to prevent stroke and other related complications in patients. This can increase the number of red blood cells in the body that can help reduce the symptoms.

 ;


	
	Stem cell transplant
	


It is also called a bone marrow transplant and is used to replace affected bone marrow with a healthy one. This procedure is carried out between matched donor and recipient. Although it is a known cure for sickle cell disease, various risks involved make it a less used practice.

 

Can Sickle Cell Be Cured?

Your body needs some cholesterol to produce hormones and vitamins that help in digestion. Two types of lipoproteins   ldl cholesterol and hdl cholesterol   are responsible for carrying cholesterol to and from the cells in your body.

Hdl or high-density cholesterol is good cholesterol. It carries bad cholesterol away from the arteries and other body parts back to the liver to be processed by the liver.

Ldl or low-density cholesterol, also known as the bad cholesterol, contributes to fatty build-ups within the arteries. This results in narrowing of the arteries and increases your risk of cardiovascular diseases like pad, heart attack, or even stroke.

Although there are medications to bring down ldl cholesterol levels, your doctor may recommend using therapeutic lifestyle changes to see how well your cholesterol levels can be managed without medications.

How to reduce  bad  cholesterol naturally

You can lower ldl cholesterol levels naturally with the following measures  

Diet and weight loss

Being obese or overweight not only increases the odds of developing high ldl levels but also contributes to cardiac diseases and chronic conditions. Studies suggest that losing even a little weight may help reduce ldl levels.

Your diet plays an important role in losing excess fat and maintaining ideal body weight. Eating the right kind of food   such as those that contain a good amount of monosaturated fats, phytosterols and soluble fibre   can help lower harmful ldl cholesterol and increase the levels of hdl cholesterol in the blood. Focus on eating whole grains, fruits and leafy vegetables, legumes, nuts and seeds, and fatty fish.

Exercise more often

Exercising regularly, in moderate amounts, can bring down your cholesterol levels and promote weight loss. Any form of cardiovascular activity, such as cycling, running, swimming and jogging benefits your heart health. You may also turn to other forms of exercise   weight training or yoga   as they also work to decrease the levels of bad cholesterol.

Quit smoking

Smoking causes a number of chemical changes in your body. Cigarette smoke increases bad cholesterol (ldl) and triglycerides levels. This leads to the accumulation of waxy plaque, which clogs the arteries. At the same time, smoking reduces the level of good cholesterol   the one that prevents the formation of plaque in your blood. Quit smoking and turn to a healthier lifestyle to see a difference in the levels of your ldl cholesterol.

Limit alcohol consumption

According to studies, heavy alcohol consumption or drinking more than what is considered moderate significantly increases bad cholesterol, which again raises triglyceride levels and ldl cholesterol.

Lifestyle changes are the natural and first line of treatment for people with high cholesterol levels. However, if your doctor suspects these levels could put you at risk of other medical conditions, he/she might recommend medications to manage bad cholesterol.

Reduce LDL Cholesterol With These Easy Steps

People with sickle cell disease often experience myriad symptoms of the disease that can be controlled by the right nutrition. Reports suggest that nutrition is an increasingly significant factor to prevent symptoms such as slow growth, lower body mass, joint issues, infections, pain crises, and anemia.

There is a greater than the typical requirement for both calories and micronutrients.

The nutritional requirement of a sickle cell patient emphasizes more on vegetables, fruits, whole grains, and more similar food items. These can prevent any deficiencies in the body and also decrease any chances of disease exacerbation.

 


	
	High-calorie nutrient-dense diet
	


The usual energy intake in a sickle cell patient is normally lower than the average values. It is a case even when the condition is asymptomatic where the requirement drops to half the level. As a result, people with sickle cell diseases (especially kids) are at higher risk for impaired growth and considerably lesser fat and fat-free mass, with obesity also posing a risk. It is suggested to have adequate energy supplements in the diet to reach the minimum sufficient requirement of the body that can be done only by proper nutritional assessment.


	
	Adequate fluids
	


Avoiding dehydration is another significant factor to avoid any severe symptoms of sickle cell disease. Sickling of the erythrocytes aggravates in patients who perform hardcore physical work in the heat without drinking enough fluids. This leads to dehydration and can even result in constipation.


	
	Micronutrients
	


Micronutrient deficiencies can be found in sickle cell patients up to a great extent. Several vitamins and minerals like vitamin a, b6, c, e, carotenoids, zinc, and magnesium are often found in fewer numbers in scd patients. A significant drop in blood-antioxidant status may result in acute chest syndrome. The supplementation of these vitamins and minerals can reduce the number of sickled cells in the body. Plant phenols and flavonoids may also help in lowering oxidative stress.


	
	Calcium-rich food
	


Getting plenty of calcium-rich food like dairy products, leafy vegetables, cereals, and fruit juices aids the child's growth and development. This may lead to a stronger physical structure and a greater resistance to the disease.


	
	Omega-3 fatty acid
	


There are reduced proportions of omega-3 polyunsaturated fatty acids in sickle cell patients. These acids aid the fluidity of red blood cell membranes. As a result, they prevent sickle cell crises. Supplemental docosahexaenoic (dha) and eicosapentaenoic (epa) have shown numerous therapeutic benefits in scd patients.


 ;

Role Of Nutrition In Sickle Cell Disease

Blood is one of the most crucial elements of human existence. It works as a commute for oxygen and various nutrients in reaching the cells. These functions make blood a vital source for the body to operate. That said, india needs 38, 000 blood donations every day, which adds up to 5 crore units required in a year. However, only 2.5 crore units are available against the huge unfulfilled numbers. Hence, it is essential to recognize the importance of blood donation.

 

Why is blood donation important?

While blood donations are essential to help people with surgeries, they are equally vital during cancer treatments, chronic diseases, and gruesome injuries. Moreover, they also benefit the donors in a significant way.

 ;

Types of blood donations

Blood donations are of several types through which a single donor has the potential to help nearly three people.

 

Whole blood donation

It is the most common process of donating blood. One pint of blood collected supports numerous patients in the process. It is, then, divided into different components that aid the donation.

 ;

Plasma donation

The process of plasma collection is carried out through a method called apheresis. It divides plasma from other blood components. Its blood clotting abilities help trauma patients and people undergoing cancer treatment.

 

Platelet donation

The collection of platelets is also done using apheresis. Once identified in the donor s blood, the rbcs and the donor gets other fluids back. Cancer patients are the chief beneficiaries of platelets as they play a prominent role during cancer treatments.

 ;

Double red cell donation

Red blood cells are also collected through the apheresis process. It helps donors to donate twice the dose of a whole blood donation. One can help a patient suffering from blood loss using this method.

 

Advantages of blood donation

Blood donations have several advantages that people should know. They help fight many severe health conditions in the human body. Some of them include-


	
	Loss of blood due to internal or external injuries caused by accidents
	
	
	Sickle cell disease or other abnormalities that affect the blood
	
	
	In the treatment of cancer
	
	
	Cardiovascular or orthopedic surgeries
	
	
	Blood disorders
	
	
	Transplant processes
	
	
	Treatments involving plasma
	


 ;

Covid-19

According to food and drug administration (fda) reports, patients who have recovered from covid-19 can help others by donating blood plasma. They contain antibodies that fight the infection, helping their body fight the virus.

 

Benefits for the donor

Even the donors receive many health and social benefits because of blood donation. Where donated blood saves lives, experts suggest that donors can also benefit from the same. Some of these advantages include:

 ;


	
	Boosting cardiovascular health
	
	
	Maintaining blood pressure
	
	
	Contributing to the community
	
	
	Reducing the iron levels
	
	
	Improving overall health
	



 

Why Blood Donation Is Important?

Get in touch with a top Diabetic Foot Surgeon online and consult with Lybrate's doctors today.


Consult with a Diabetic Foot Surgeon - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES