Insulin is the most common treatment prescribed for people affected with diabetes. Diabetes is condition where high amounts of glucose prevail in the blood for an extended period of time. However, there are some drugs that offer an alternative to insulin in treating diabetes, which are:

1. Liraglutide: Liraglutide is a glucagon-like peptide-1 (GLP-1) drug that causes the body to release greater amounts of insulin so as to facilitate the movement of glucose from the blood to the cells. People with type 2 diabetes generally use this treatment. It slows the digestion process and can cause symptoms of headache and nausea. 

2. Pramlintide: It's an artificially produced version of amylin. It is taken by both type 1 and type 2 diabetic patients, facilitates slower digestion of food and therefore, controls release of sugar in the blood. It can cause tiredness and nausea.

3. Dulaglutide:This treatment is for people affected with type 2 diabetes and it is administered once a week. It causes more insulin to be released and pass the glucose to the cells. It can cause loss of appetite, nausea and abdominal cramps as side effects.

4. Albiglutide: This treatment facilitates pancreas to release insulin and limits the glucagon hormone production. It is used by type 2 diabetes patients who have not taken well to other treatments. The side effects are skin reaction, respiratory tract infection and nausea.

5. Exenatide: It is a drug that causes pancreas to release insulin that facilitates movement of glucose to cells. It is a treatment for type 2 diabetes and it restricts release of glucagon in the body. The possible side effects are acidity, constipation and vomiting.

Common Insulin Alternatives

Your skin is the largest and most sensitive organ of your body. Funguses that live in the human body especially armpits, groin area, nails, and feet, cause fungal skin infections. Weak immunity is the leading cause, with over 300 million people fighting fungal infections globally, every year.

Some of the common types of fungal skin infections are-

  Athlete s foot- Also known as Tenia pedis, Athlete s foot occurs when the tenia fungus begins to grow on your feet. It is most commonly associated with athletes because it grows in warm and moist climates such as in socks, near swimming pools and in locker rooms.

Symptoms of athlete s foot  

Infected area becomes soft and layers of skin begin to peel off
Redness, blisters, and cracking of skin
Treatment includes applying of topical antifungal ointments such as terbinafine while, severe cases may require oral medication.

  Ringworm   Ringworm is a highly contagious skin infection and is spread by person-to-person or pet to person contact. The fungus can also spread through infected towel, clothes, and mud.

Symptoms of Ringworm  

Red itchy patches on the skin which develop into raised ring like bumps
Formation of scales on the patches
Treatment of the infection includes medicines like miconazole.

  Jock  s itch- Also known as Tinea Cruris, these fungi thrive in moist and warm areas of the body such as the groin, inner thighs and buttocks.

Symptoms of Jock s itch  

Itchy red circular rashes over the body and burning
Chafing and peeling of the infected area
Treatment includes prescribed medication and maintaining personal hygiene.

Prevention is better than cure when it comes to fungal infections. Visit a doctor at the first signs of infection. A medical exam is the best way to detect the cause of a skin infection.

Fungal Infection Of Skin And Its Treatment!

Why osteoporosis and osteopenia are fast turning into diseases of the young

Did you know that osteoporosis causes more than 8.9 million fractures worldwide every year? what is frightening is many of these fractures are now taking place among the youth due to deficit diet and poor lifestyle coupled with genetic predisposition. Both osteoporosis and osteopenia are two forms of bone loss conditions, with the latter being a precursor to the former. To distinguish between the two a bone mineral density test is usually performed.

What is the difference between osteoporosis and osteopenia?

A BMD (bone mineral density) t-score between -1 sd and -2.5 sd indicates osteopenia with a high chance of osteoporosis. On the other hand, a t-score of -2.5 sd and below stands for osteoporosis. A higher bone density (above -1sd) is usually indicative of stronger bones. Fragility index is more accurate way to assess the risk of fractures.

In osteoporosis the bone loss or weakening of bones take place over a long period of time, and results in unexpected fractures and severe bone problems. Disfigurement, fractures in the spine, loss of mobility and independence are usual characteristics of this bone disease once it progresses further.

Prevention is better than cure, always!

To keep bones strong and healthy, calcium and phosphate is continuously absorbed by the body. But after 30, the body?s ability to absorb calcium slows down and there?s a decrease in the production of new bones. In contrast, bone desorption (the process of transferring calcium from the bone to the blood) continues unabated.

When the body starts absorbing the store of calcium in the bones to meets its needs, it leads to calcium depletion and is one of the causes of the weakening of the bone.

At present, the age limit (50-60 years) for osteoporosis has seen a drop with many younger people increasingly suffering from the ailment. Factors like unhealthy lifestyle, late-night shifts, smoking and alcohol consumption have been found to be the culprits behind the rise in osteoporosis cases among the young. Recent studies have identified vitamin d deficiency as a major factor for poor bone health and bone mass density in the young.

How to keep your bones strong and healthy? and manage osteo - penia/porosis complications:

Bone loss can be prevented by adopting these very simple but effective ways:

- exercising can help in building strong bones and muscles, while preventing bone loss.

- maintaining a calcium intake of 1000 mg for pre-menopausal women and 1200 mg for women post menopause.

- staying out in the sun for 20 minutes to produce requisite amount of vitamin d for calcium absorption and using supplements of vitamin d.

- there are many safe medicines available to prevent and treat osteoporosis like alendronates, calcitonin, parathyroid, teriparatide preparation etc.

- in osteoporosis induced /associated fractures we have to to modify implants to negate weak purchase of implants in bone and improve mobility. We have been using these modifications in established osteopenia/porosis case in fractures treatment/joint replacement/ arthroscopic fixations and MIS spine fracture management.


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Are Osteoporosis and Osteopenia fast turning into diseases of the young?

Are you losing your sight day by day? Does it make difficult to see you at night? Is this the onset of Blindness? Get to know about Retinitis Pigmentosa with these tips.

What actually is Retinitis Pigmentosa? 
Retinitis Pigmentosa (RP) refers to a group of diseases, which causes a slow, but progressive vision loss. It is a genetic disorder that affects the ability to respond to light.This inherited disease causes a slow loss of vision, beginning with decreased night vision and loss of peripheral (side) vision and eventually results in blindness.

Causes:
Retinitis pigmentosa is often hereditary (runs in families). If you or your partner has retinitis pigmentosa, there may be up to a 50 percent chance that you will pass it on to your children. Ask your ophthalmologist about genetic counseling if you are planning to have children.

Symptoms:
1. Slow loss of vision
2. Beginning of decreased night vision
3. Loss of peripheral vision
4. Difficulty in identifying colours

Diagnosis:
If you have poor night vision or a loss of side vision or if there is a history of retinitis pigmentosa in your family, your ophthalmologist will conduct a comprehensive eye exam to determine if you have retinitis pigmentosa. Your ophthalmologist will dilate your eyes to look at the back of them for signs of disease.

Treatment:
Currently there is no known cure for retinitis pigmentosa. However, research has shown that vitamin A palmitate may slow the progression of certain forms of RP. Your ophthalmologist can advise you about the risks and benefits of vitamin A palmitate and how much you can safely take. Taking too much vitamin A palmitate can be toxic, and evidence of vitamin A palmitate effect on RP progression is not substantial.
Another recommendation for slowing vision loss from RP is to wear sunglasses to protect your retina from harmful ultraviolet (UV) light.

Retinal prosthesis is also an important area of exploration because the prosthesis, a man-made device intended to replace a damaged body part, can be designed to take over the function of the lost photoreceptors by electrically stimulating the remaining healthy cells of the retina.

Retinitis Pigmentosa: What You Should Know About It?

Peptic ulcer disease is a form of disease in which painful sores or ulcers are developed in the lining of the stomach or in the duodenum, which is the first part of the small intestine. Complications include severe blood loss and perforation of the stomach and intestines.

What can cause peptic ulcers?
Ulcers occur due to the imbalance of digestive fluids in the stomach or duodenum. Usually, ulcers are caused by the infection due to bacteria known as Helicobater pylori.
Here are the factors which may lead to peptic ulcer:

    One can use painkillers, which are known as nonsteroidal, anti-inflammatory drugs, by the likes of aspirin, naproxen, ibuprofen and several others.
    These kinds of ulcers may also occur due to excessive production of acid from gastrinomas.
    Excessive alcohol consumption may also cause peptic ulcer.
    Smoking cigarettes and chewing tobacco may cause such ulcers.
    Sometimes serious illness may cause peptic ulcer as well.
    Radiation treatment of the affected area may also lead to peptic ulcer.

What are its signs and symptoms?
There are several symptoms of peptic ulcer. They include the following:

    People experience a sensation of burning or gnawing pain in the upper or middle part of the stomach, between meals and during night time.
    Bloating is experienced.
    A feeling or sensation of heartburn.
    Nausea and vomiting are likely to be accompanied.
    In severe cases of peptic ulcer, dark or black stool is produced because of bleeding.
    The patient may vomit blood.
    Weight loss and abdominal pain are indicated, especially in the upper to mid abdomen region.
    Indigestion and change in appetite are also noticed.
    There is pain in the chest.

How to treat them?
Peptic ulcers can be treated in various ways, which include medication, lifestyle changes or surgery.
1. Lifestyle changes: Elimination of substances which lead to peptic ulcer should be avoided. Smoking and drinking should be restricted. Certain NSAIDS may lead to ulcer, and they should be stopped.
2. Medication: Proton pump inhibitors help in reducing acid levels, which allow healing of the ulcer. Different types of PPI are esomeprazole, dexlansoprazole, omeprazole, pantoprazole and iansoprazole.

Several antibiotics may also be used when a patient has helicobacter pylori infection. Several combinations of antibiotics may be used for the treatment. Bismuth may be used as well.
Upper endoscopy can be done as a part treatment of ulcer to cure bleeding ulcers. In case the ulcer creates a hole in the stomach s wall, surgery is required. Peptic ulcer is a serious health condition and if not treated properly, it can cause several health hazards. There are several treatment options for peptic ulcer, and you should opt for the one that suits you the best.

Peptic Ulcers - 6 Possible Reasons Behind them

Role of relationship problems in depression and suicides - 
Almost everyday we read about people ending their lives by committing suicides from celebrities to common man to even children . Although this is not permitted in any religion and there is a legal debate on whether it should be legalized, the fact remains that people are driven towards this unfortunate step. Let's take a look at the common reasons for suicides to become so very common.

1) Lack of intimacy- We see that although we are surrounded by people most of people are having friends only on Facebook. Even among the people we interact everyday nobody wants to open up with anyone or allow you to open up with them.The fact that you are surrounded by people who don't share themselves with you intimately starts pulling your mind downwards. Work colleagues are bothered only about work, family is only bothered about the income you are generating, partners are obsessed with how much you can spend on them, friends are occupied with what benefits you can share with them. Therefore all in all, despite having all relationships, people feel left out and alone like as if their inner self has been left unwanted and uncared of. The monotony of mechanical life hastens the culmination of this abuse into drastic steps like suicide.

2) High demands- People are often left to fend with high demands from them from their social circle. Many people cannot attempt this and some who attempt are not able to make it. This leaves them with a feeling of failure which is often frowned and looked down upon whether it is a student or a professional. It is no surprise that today even below 10 years olds are successfully attempting suicides.

3) Inappropriate planning- Planning is a key necessity for successful results whether it is financial or relationships. but unfortunately many people are unable to obtain the correct know how which will enable to implement their plans successfully.

4) Inability to cope- Many people plan to do things but are unable to cope with the harsh realities that come with the plans. To some it may be unseen to some unbearable. So although they set out on doing something the journey is not what they had expected.

5) Lack of results- Sometimes although everything is planned well, executed well and completed well it does not fetch us the rewards that may seem appropriate to the level of efforts. This is something that is very difficult to deal for most people and is a result of many unfortunate casualties.

6) Lack of desire-It is very important to have something to look forward to in life. But unfortunately in an age where drinking water and using the toilet cost s money many people cannot think of having something to look forward to and hence this unfortunate step.

Therefore, you have to be very prudent in what we are doing today because we can never predict which way our lives may go and even importantly which way you may yourself go based purely on circumstances beyond our control dependent on the choices we make today or others make for us. Although suicide is not a sensible solution to any problem it does remain a common reality. If you are feeling suicidal please remember to seek help.

Please feel free to consult me privately for further assistance.

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Health Tip - Role of Relationship Problems in Depression and Suicides

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