How many of us know that a deficiency of Vitamin B6, also known as pyridoxine can make you susceptible for heart disease, brain degenerative diseases like Alzheimer s as well as muscle pain, depression and dragging fatigue?

Vitamin B6 is one of the most crucial vitamins for health and it s a part of the vitamin B complex family. Now, all B vitamins, including vitamin B6, play an important role in a number of life-altering physical and psychological functions. All of them have a vital role to play in helping to maintain a healthy metabolism, nerve and liver function as well as skin and eye health, as well as good amount of energy levels.

Role of Vitamin B6
Vitamin B6 or pyridoxine has a number of derivatives, including pyridoxal, pyridoxal 5-phosphate and pyridoxamine. And all of these are involved in major body functions like movement, memory, energy use and blood flow. This is the primary reason why a vitamin B6 deficiency can show up in a range of symptoms from physical to psychological, temporary to chronic and serious.
Vitamin B6 also helps your body to

Maintain a healthy nervous system

To make more hemoglobin, blood cells that carry oxygen in blood
To provide energy from our food
To balance blood sugar levels
To act as a natural pain relief
To boost mood
To create antibodies for self-protection
Preventing a Vitamin B6 Deficiency
The recommended amount of vitamin B6 for an adult under the age of 50 is 1.3 milligrams. Normally, this amount is easy to get from your diet, assuming you are eating a balanced diet with enough calories. However, the amount the body s requirement for vitamin B6 jumps up as you age. Experts recommend that adults over 50 get up to 1.7 milligram daily of this vitamin.

As this requirement is not met, older people get more prone to a vitamin B6 deficiency and so do malnourished children and adults. Foods like poultry, pork, nuts and beans contain high levels of vitamin B6 and you can include more of these to get the recommended dose of vitamin B6. However, since vitamin B6 is a water-soluble vitamin, so you need to replenish your body with it daily as it doesn t get stored in the body.

Symptoms of Vitamin B6 deficiency:
Lack of energy and chronic fatigue: Vitamin B6 helps supply your body with energy by improving your metabolism. It has a vital role to play in protein metabolism   it helps your body break down the protein that you eat and produce energy quickly. So one very important pointer that you have a vitamin B6 deficiency is when you get fatigued quickly during exercise.
Brain function decline: Vitamin B6 vitamin helps your brain communicate with other parts of the body more efficiently. So, if you have a decline in muscle efficiency it could be a sign of vitamin B6 deficiency.
High Levels of amino acid Homocysteine: High levels of amino acid Homocysteine do not cause any symptoms that you can detect by yourself but tests can tell you if you have high levels of this amino acid in your body. And these high levels are directly linked to vitamin B6 deficiency. What high levels of homocysteine can do is cause heart attacks. But vitamin B6 helps keep a check on these levels to reduce your risk for a cardiovascular event.

Other symptoms of vitamin B6 deficiency are:

Changes in mood, such as depression, irritability, and anxiety
Confusion
Muscle pains
Fatigue
A worsening of PMS symptoms
And worsening of symptoms of anemia
As vitamin B6 is so important for nerve function, a deficiency is linked with neuro-psychiatric disorders like seizures, migraines, and chronic pain.
An increased risk of heart disease and rheumatoid arthritis
Higher risk for Alzheimer s disease and other forms of dementia.

Vitamin B6 Deficiency- Signs You Are Suffering From It!

Gastric (stomach) cancer occurs when malignant cells form in the lining of the stomach. By far, it is known to be the second most common cause of cancer-related deaths not only in Asia but also worldwide. Though it can affect both male and female populace, it is seen more commonly in men and in people aged 50 years or older.

Type: Gastric cancers can present as one of the following types - 

Adenocarcinoma: Begins in the glandular cells lining the inside of the stomach. This forms a majority of the stomach cancers.
Lymphoma: Begins in immune system cells present in the walls of the stomach. Occurrence of lymphoma, in the stomach, is rare.
Carcinoid Tumor: Begins in hormone producing cells of the stomach.  Occurrence of carcinoid cancer, in the stomach, is rare.
Gastrointestinal Stromal Tumor (GIST): begins in nervous system cells of the stomach. Occurrence of GIST, in the stomach, is rare.
Gender: It affects both male and female populace.

Etiology: The factors that are associated with increased risk of gastric cancer include the following mostly  

 Helicobacter Pylori  bacterial infection in the stomach is a common cause of gastric cancer of both the intestinal (expanding) & diffuse (infiltrative) type. Furthermore, studies indicate that high salt intake is synergistic with H. Pylori infection in the manner that it is likely to increase the risk of gastric cancer that is induced by H. Pylori bacteria.
Smoking, consuming alcohol, red meat, salty/ smoked/ processed foods, low intake of fruits and vegetables, diets rich in nitroso compounds, eating foods contaminated with aflatoxin fungus etc all.
Atrophic gastritis characterized by chronic stomach inflammation is known to increase the risk multi-fold. Chronic gastric inflammation can lead to atrophy of the gastric mucosa, metaplasia, dysplasia and finally carcinoma.
History of pernicious anaemia, gastric ulcers, adenomatous gastric polyp etc all.
Family history of gastric cancer. Several familial syndromes that have been associated with a pre-disposition to gastric cancer include familial adenomatous polyposis, Lynch syndrome, Peutz-Jeghers syndrome and e-cadherin mutation (diffuse type)
Blood group A, Obesity etc all are known to be associated with diffuse or cardia gastric cancer.
Low socioeconomic status - persistent lifestyle issues/ irregularities including high stress coupled with an improper diet/ dietary pattern.
Epidemiological evidence is indicative of a risk or pre-disposition to gastric/ stomach cancer for people suffering from diabetes mellitus (DM).
Very high dose ionizing radiation exposure is an uncommon risk for gastric cancer.
Features: There are often no early stage symptoms. Early stage symptoms, if any, are non-specific and are likely to be ignored, thus delaying the diagnosis most often. Hence, gastric/ stomach cancer is often detected at an advanced stage where the disease is either locally advanced or metastatic. The various presentations (of signs & symptoms), by stage (early or advanced), of gastric cancer are as enumerated below:

Early Stage   can present with one or more of the following non-specific symptoms/ signs -

Dyspepsia (Indigestion),
Stomach/ Epigastric discomfort,
Bloated feeling after eating,
Mild Nausea/ Vomiting,
Blood in Vomit (Haematemesis),
Heartburn,
Weight loss (Cachexia)
Anaemia,
Occult blood in stool/ Melaena,
Advanced Stage   presents with one or more of the following symptoms/ signs -
GI Bleeding with black tarry stools (Melaena),
Persistent Nausea/ Vomiting,
Blood in Vomit (Haematemesis),
Early Satiety,
Anaemia,
Loss of Appetite (Anorexia),
Weight loss (Cachexia),
Persistent pain in the abdomen,
Fluid build-up in the peritoneal cavity (Ascites),
Edema of the lower extremities,
Liver Enlargement (Hepatomegaly)/ Jaundice,
Difficulty swallowing food (Dysphagia)
Screening: Is generally recommended for asymptomatic populations in high incidence areas or as surveillance for high risk individuals. The goal of screening, as usual, is to be able to detect & diagnose gastric cancer at an early stage which is potentially curable. It is mostly endoscopic/ radiologic.
Diagnosis: Following are the diagnostics employed in gastic cancer - 

Physical Examination: May be remarkable for palpable abdominal mass, weight loss (cachexia), abdominal distension, ascites, hepatomegaly, lower extremities edema and lymphadenopathy for gastric cancers in the advanced stage. For early gastric cancers, however, physical examination is largely uninformative.
Blood: Hb- may be low, ESR   raised, tumor markers CEA & CA-19-9 could be raised sometimes in adenocarcinoma but are not frequently elevated. Abnormal blood test results may be indicative of malignancy, but a follow-up gastroscopy/ biopsy is always the gold standard for accurate diagnosis.
Stool: Occult blood may be +ve
Barium Meal X-Ray: Could show a filling defect at the site of the carcinoma/ cancer growth.
Gastroscopy/ Biopsy: Clinches the diagnosis.
Endoscopic Ultrasound: Maximizes tumor staging as it helps determine the depth of invasion of the tumor.
CT Scan: Of chest, abdomen & pelvis helps detect metastatic disease, if any, and also helps stage the disease (TNM) appropriately.
Bone Scan: Helps detect osseous metastasis (bone mets), if any.
Treatment: Conventional treatment includes surgery, chemotherapy and radiotherapy as contextually appropriate. Surgery (i.e. gastrectomy either sub-total or total), with an adjuvant chemotherapy and/ or radiotherapy as contextually relevant, is the only treatment that is known to cure the disease in light of the prognostic indicators as briefly enumerated in the section below. Chemptherapy and/ or radiation alone cannot be curative. Mostly, it can improve symptoms, and may prolong survival. Simultaneously, an adjunctive or integrative naturopathic treatment with suitable complementary & alternative medicines (CAM) too can help improve clinical outcomes and facilitate recovery as feasible contextually.
Prognosis: For gastric cancer is variable. Preventive measures, earlier diagnosis and right early treatment is key for an effective therapeutic management & better prognosis. Like most other cancers, the chances of cure for an early stage gastric cancer are more. The cure/ recovery chances are influenced by the grade, stage of cancer, recurrence and the patient s general health & vitality etc all. Distal tumors are known to be cured more often than the proximal ones. Again, intestinal-type gastric cancers are known to have a better treatment outlook in comparison to the diffuse-type gastric cancers.

Prevention: Rightly said, prevention is always a better choice. Although genetic risks are difficult to modify, still an adherence to a relative Mediterranean diet, maintaining an ideal body weight and an active lifestyle with due emphasis on regular exercising, de-stressing and relaxation is highly recommended for reducing the risks of many cancers including gastric cancer. A healthy eating plate comprises essentially a low fat diet, fibre rich foods including whole grain cereals, green leafy vegetables cooked using healthy vegetable oils, fresh fruits of all colours as seasonally available and healthy proteins/ fats including fresh fish, poultry, beans, nuts etc all. The consumption of alcohol, if any, has to be strictly in moderation, and is best avoided in a high risk scenario. Smoking is to be avoided too. Again, red meat, butter, refined grains, sweets, sugary drinks including carbonated beverages and other high calorie foods etc all, if any, are to be taken sparingly. Not only it is important to eat healthy, but also it is equally important to eat properly. Insufficient chewing, eating until full, eating meals within a short time etc all are best avoided so as to ease off digestive burden on the stomach/ other organs in the GI tract. Last but not the least, consumption of clean and filtered water, natural probiotics like freshly prepared yogurt/ butter milk, maintenance of cleanliness & hygiene including oral hygiene etc. all can help guard against H. Pylori infections. Breastfeeding is known to be protective against H. Pylori infections too.

Gastric Cancer - In a Nutshell!

What you must know about body ache


Affecting your entire body, body ache is usually an indicator of a condition that requires your attention for the pain to stop or a reaction of your body's immune system to an infection. Understanding the symptoms and the cause of the pain is the first step towards getting the right treatment for your problem.
The causes of body ache can be any one of these:
  an increase in your body's lactic acid as a result of overused muscles (that you normally experience when you perform strenuous exercises) leads to body aches that are not severe but temporary in nature.
  temporary body aches can also occur if you suffer from flu caused by the influenza virus and other medical conditions like fever and viral infections, among others.
  a cause of body aches can be the presence of a serious condition such as Lyme disease or pneumonia that brings about major infection affecting your entire body.
  inflammation of body cells or damage to your body's nervous system in the form of chronic ailments like autoimmune diseases and psychiatric problems can also cause pains and aches to develop all over the body.

What can you do to manage it?
There are simple ways that you can employ to relieve your body aches based on the root cause and these are:

  if the cause of your body ache is the flu, the best way to alleviate your condition is to take a hot bath. The hot water works by eliminating the body pains you may be suffering from. Even a gentle massage can soothe the ache affecting your entire body.
  for body aches that are caused due to overused muscle, you need to apply ice packs for 2-3 weeks on the affected area to bring down the inflammation. Even the application of a heating pad can help in relieving body aches brought on by muscle soreness.
  shoulder and neck pains can be easily prevented by performing simple exercises from time to time such as shoulder shrugs or head turns. Also, the practice of using wrist and forearm rests can reduce your chances of getting shoulder and neck aches.
  reducing your stress levels can also help in effectively lowering the instances of body ache. From sleeping on time to meditating for about 20 minutes a day can help in lowering stress.

In case, you do not get relief from any of the suggested ways, you need to consult a qualified doctor who will guide you on the right treatment course. 

If you would like to consult with me privately, please click on 'consult'
Related Tip: Why does PAIN occur? Understand the Mechanism of Pain

Body Ache? Here's What You Must Know about Body Pain

Mind your headaches (All about headaches)

Headaches and migraines are one of the most common types of pains that patients can face. There are many types of headaches that may afflict people and there are a number of reasons that can be attributed as their cause.

Let's look at some of the types of headaches and their causes:

Facial headaches

This is an ache, which is usually centered on the face, the crown, and the forehead. In this headache, movements of the head and face may also cause problems.

Causes: The main cause for facial headaches tends to be sinusitis, a condition in which the cavities in the skull get blocked. Sinusitis may also happen due to a cold as this has often been accompanied by a runny nose as well.

Treatments: The best treatment for this issue would be to treat the underlying condition, i.e. the cold or the blockages. Using the prescribed variety of decongestants and inhalers can vastly improve the situation.

Migraines

This is an intense pain on one side of the head that can last for a few hours to a few days. Most of the pain is sometimes centered behind the eye, and many people report extreme sensitivity to light as well as sound. It can be debilitating to some people who suffer from a severe form of it.

Causes: Migraines are one of the most complicated problems to diagnose and there can be a variety of reasons for it. Triggers may include food or lack of it and also be caused by other underlying physiological reasons.

Treatments: Although there are certain painkillers, which are available, it is best to consult a doctor to know the root cause and thus, avoid the triggers or take appropriate medicines if necessary.

Tension Headaches

These headaches are induced by periods of stress, anxiety, anger and other mental distresses.

Causes: These headaches are a result of stress, which may result in the decrease of the blood flow to the brain due to the stiffening of the head and neck muscles.

Treatments: Over the counter drugs such as paracetamol or ibuprofen can help improve them, but it is better to consult a physician before undertaking self-medication.

Cluster Headaches

These are the most potent form of headaches that can be very painful. They usually originate as a piercing pain in the head with pressure on the eye and can even lead eye inflammation, and watery and droopy eyes.

Causes: Certain neural functions originating from the hypothalamus can cause this issue and this type of headache may be triggered by alcohol, smoking or other forms of strong smells.

Treatments: Generic painkillers may not be able to correct the issue quickly enough and this may require the administering of special injections or nasal sprays.



All You Need To Know About Headaches

The coronary arteries supply the heart with oxygen-enriched blood and nutrients. If these arteries become damaged or diseased; they could cause Coronary artery disease or CAD. Plaque deposits on the walls of the arteries are the most common cause of this disease. This plaque is usually the result of high cholesterol levels. As the plaque builds up, the passage of blood flow is reduced. This reduces the amount of blood that reaches the heart. In cases of a complete blockage, CAD can even cause a heart attack. Because of its slow progression, this disease is often not diagnosed until it reaches a dangerous stage. However, it can be prevented and treated if diagnosed in time.

In the early stages of CAD, symptoms are not very noticeable. Symptoms become visible only when blood flow to the heart reduces and the heart has to pump harder than normal. The most common symptoms experienced include:

Chest Pain: This is also referred to as angina. It may feel like a tightening of the chest or pressure on the chest as though someone is pressing against it. This type of chest pain may be triggered by emotional or physical stress. It is usually relieved within a few minutes of stopping the activity. Women may experience this pain as a sharp, fleeting pain in the back, arm or neck.
Breathlessness: When the heart does not receive enough blood, it has to work harder to pump blood through the body. This may be translated to breathlessness of shortness of breath when performing any type of physical activity. It can also cause extreme fatigue.
Heart Attack: A heart attack is the most severe symptom of coronary artery disease. This is caused by the complete blockage of a coronary artery. A heart attack can occur without any symptoms or be preceded by slight symptoms. The signs of an impending heart attack include pain in the chest and shoulder, shortness of breath and extreme sweating. The chest pain may also travel to the lower jaw. These symptoms are more pronounced in men as compared to women. Women have a higher tendency of experiencing atypical signs such as extreme fatigue.
Other symptoms that might indicate coronary artery disease are dizziness, nausea and an irregular heartbeat. The good news is that this disease can be prevented. Staying physically active, maintaining a healthy weight, reducing stress and eating a low fat and low salt diet can help reduce the risk of CAD.

Coronary Artery Disease (CAD) - What Are The Symptoms?

Irritable bowel syndrome is a disorder, which generally affects the colon (large intestine). It usually show symptoms like abdominal pain, cramping, bloating, diarrhea, gas and constipation. IBS is a long term condition. It can result in sudden mood swings, depression and thus, holds you back from living your life to the fullest. IBS can be controlled by managing lifestyle, stress and managing your diet. Medication and counseling could also be required to manage IBS.

Symptoms of IBS:
1. Immense cramping and pain.
2. A feeling that your belly is bloated all the time
3. Severe gas
4. Alternating and sudden bouts of constipation and diarrhea.
5. Presence of mucus in the feces.

Whenever you experience such kind of symptoms, it is always advisable that you must consult a doctor, so that it doesn't lead to a serious condition.

When should you consult a doctor for IBS?
IBS is not a chronic disorder and can be controlled by home remedies. It may also require medical treatment if the symptoms become acute and persist for too long. If you experience certain symptoms like rectal bleeding, weight loss and heavy abdominal pain that might increase at night, you may be at a risk for colon cancer. If such symptoms persist, you should visit a doctor as soon as possible.

Causes of IBS:

Foods: Most people are susceptible to IBS if they consume foods like spices, fats, fruits, cabbage, beans, broccoli, cauliflower, carbonated beverage, milk or alcohol. These foods irritate the lining of the stomach and trigger IBS. However, the trigger may vary from person to person.
Stress: Signs and symptoms of IBS can also increase if you are very stressed out. Stress makes your muscles too worked up and this may result in IBS. However, you should know that stress aggravates or triggers the symptoms but doesn't cause IBS.
Hormones: Women are more likely to develop IBS. Fluctuations in the hormonal cycle can trigger IBS. This usually occurs around or during menstruation.
Other illnesses - Sometimes illness such as gastroenteritis (infectious diarrhea) or bacterial overgrowth in the intestines can trigger symptoms of IBS.
Age: You will be more likely to develop IBS if you are 45 years of age or above.
Hereditary: People having a family history of IBS are more susceptible to develop IBS.
Mental problems: Depression, personality disorder, anxiety and a history of sexual abuse can also trigger symptoms of IBS.

Irritable Bowel Syndrome - Can Severe Gas be a Sign of it

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