Neurological disorders are an enigmatic bunch. There are various ongoing researches to identify the exact cause and how to treat them. While some argue that schizophrenia is a chronic brain disorder, others do not agree with it and debate that the origin is yet to be identified and the factors which produce it are yet to be identified.

Factors supporting it to be a brain disease are listed below.

Scan images (MRI and PET scans) of people who have had schizophrenia are different and have a reduced volume of grey matter, especially in the frontal and temporal lobes. In some people, this loss could be as high as 25%. Serial images have shown that the loss begins in the outer (parietal) region and gradually spreads to the rest of the brain. There is a strong correlation between the extent of this grey matter loss and the severity of the symptoms more the loss, worse the symptoms. Severe symptoms include hearing voices, psychotic thoughts, delusions, hallucinations and severe depression. This grey matter reduction does not depend on whether the person has undergone treatment or not for the condition. 

The counter argument is that grey matter loss is not seen in patients with schizophrenia alone. A number of neurological disorders, including normal ageing, manifest as grey matter loss on the scan images. Also, another consoling news is that this grey matter loss is completely reversible.

The way neurotransmitters respond to stimuli in people with schizophrenia is also slightly different. There are two variations to this debate: that schizophrenia is caused by excessive amounts of dopamine or increased sensitivity to dopamine. There are two proofs for this hypothesis first, dopamine suppressants are useful as antipsychotic drugs and secondly drugs which produce the same effect as dopamine can cause hallucinations similar to those seen in schizophrenics. There could be other neurotransmitters involved too, but the dopamine connection is more strongly established.

The electrical activity of the brain as seen in EEG is very different and abnormal in schizophrenic people. This reduced brain activity is another indication of the fact that schizophrenia is another brain disorder. There is also a strong genetic component to schizophrenia. Family history correlation is also very strong. The correlation extends to the point that where there is a neurologic disorder in the first-degree relatives, the chances of developing schizophrenia is increased.

There are specific genes, mutations of which are also attributed to schizophrenia. While the risk factors are in place (as mentioned above), the environmental conditions (brain infections, head trauma, family/social stressors and toxins can all lead to the manifestation of the symptoms. With medications and support therapy, both prevention and symptom management are possible.

Schizophrenia - Is It Really a Brain Disease?

Schizophrenia is a psychiatric disorder in which a person s mood, knowledge, thought and several other characteristics gets disturbed. We can notice most of the adults and old people with few symptoms of schizophrenia, which are most commonly left unidentified. The exact cause of schizophrenia is not yet known. The person feels that they are being constantly watched, they feel the presence of someone or something, which is not actually there. They are always suspicious and think that other people are gossiping and thinking about them.

Possible causes of Schizophrenia
Though the exact cause of schizophrenia is not known there are few factors, which contribute to the cause of schizophrenia.

    Genetic factors: People with a family history of schizophrenia are at higher risk of getting schizophrenia.
    Environmental factors: Environmental factors include excessive stress during pregnancy or later stages of life. Several other factors during pregnancy and childhood are responsible for causing schizophrenia. These factors are:
        Decreased oxygen level during delivery due to premature birth or prolonged labour
        Parental loss or separation in early stages of life
        Parental exposure to virus or during infancy
        Childhood physical or sexual abuse
        Abnormal brain structures and brain chemistry

Sings and symptoms of schizophrenia

    Hallucination: To see, feel or hear anything that really does not exist is known as hallucination.
    Delusion: A thought or belief of a person, which is either false or impossible in reality is known as delusion.
    Thought and speech disturbances: The thought process and speech of a schizophrenic will be disorganized, due to which he or she  will fumble or is distracted as they are unable to align their thoughts.
    Difficulty in concentrating: It is difficult for people suffering from schizophrenia to concentrate on the task at hand.
    Erratic behaviour: People suffering from schizophrenia tend to behave erratically, either they will be too jumpy or will be perfectly still for hours at a stretch. Most people belief that those who are suffering from schizophrenia are often violent in nature, which actually is not the case.

Treatment for schizophrenia
Schizophrenia can be treated, if identified at an early stage. . It is best advised to consult a psychiatrist the moment you spot the symptoms. Anti psychotic drugs, self help behaviour change, counselling and rehabilitation are few treatment modalities available for schizophrenia.

Schizophrenia: Can Genetics be the Reason Behind it?

Drug addiction is one of the social menaces and in most people, what starts off as a result of peer pressure and trying to be cool ends up affecting lives significantly. It is not just social, but also affects financial, physical, emotional, and social well-being. The small periods of happiness given by the drug is followed by months and years of torment.

The National Institute on Drug Abuse (NIDA) has identified that drug addiction causes chemical and structural changes in the brain, leading to dangerous and self-destructive behaviours. The brain s response to stimulus like pleasure, joy, happiness, and pain are altered with constant drug abuse. For instance, the neurotransmitter called dopamine, which makes one feel good, is usually produced by the brain in small amounts. However, drugs increase this level to 2 to 10 times more, making the person feel extremely high and happy. Since the body is unable to reach the highest level of happiness on its own, the dependency on these drugs to feel good increases.

Repeated use of the drugs leads to increased dependency, wherein the brain refuses to feel good without reaching those high levels of dopamine. The issue is mostly seen in teenagers and young adults but can be seen in any age group.

October 2 is recognised as National Anti-Drug Addiction Day and nationwide campaigns and drives are done to help people overcome addiction. One of the main reasons a drive this size is required is because of the social stigma attached to the problem. Most families shun away from recognising it as a problem that can be easily treated, and so the affected person is sucked deeper into the problem.

Overcoming addiction: One of the main success factors for treating addiction is for the affected person to recognise that he or she is addicted and needs to get rid of the problem.

    There are national toll-free helplines that are set up, which can guide through the whole program. This way, if required, anonymity is maintained and support for overcoming addiction is increased.
    It involves a group effort involving the affected person, family and friends, medical and clinical personnel, and counsellors in some cases.
    Cognitive behavioural therapy: The person is made conscious of the change in behaviour and the way drugs affect it. Healthier patterns to be happy and joyful are discussed.
    In most cases, the underlying reason for reaching out to drugs needs to be addressed also to prevent relapse.
    Group therapies where the person makes friends who have faced similar issues and overcome the problem. This increases their accountability and commitment to getting rid of the problem.

Drug abuse is a national social menace and needs more free admittance and management.

National Anti-Drug Addiction Day - Overcoming Addiction

Schizophrenia is a debilitating mental and emotional condition that is characterised by a heavily distorted thought process as well as hallucinations and even extreme fear that borders on paranoia. Let us find out more about this debilitating disease:

Causes:
1. Genetics: genetic factors play an important role in the development of schizophrenia.
2. Environment: possible environmental factors include obstetric complications, the mother's exposure to influenza during pregnancy or starvation. It has also been suggested that stress, trauma even migration can lead to the emergence of schizophrenia. 
3. Neurodevelopmental factors: schizophrenia appears to be a neurodevelopmental disorder. That is changes that cause the illness have been occurring from the earliest stages of development even in utero, and may continue to influence the development of the brain over the first 25 years of life. 

Symptoms: 
This disease has a variety of symptoms include cognitive and emotional ones that can vary in the degree and severity. One of the most common symptoms included hallucinations and delusions where the patient may end up imagining things that do not really exist. The patient may also be gripped by sudden and crippling fear like paranoia, which can be debilitating as far as everyday functioning of the person goes. The symptoms can also interfere with the way a person deals with situations and life skills on a cognitive basis. Withdrawal and hopelessness are also a part of this disease.

Treatment: 
The earliest signs and symptoms must be referred to a psychiatrist. The treatment involves the management of the case of an individual basis along with psychological rehabilitation programs and inclusion of the patient in self-help groups. Housing and employment programs must also be availed so as to keep the patient busy. Also, behaviour therapy will be required in such cases. The mode of counselling should usually be on a one on one basis, although many doctors also suggest that group therapy can help in showing examples of progress so as to encourage the patient to change and get a new lease of life.

Schizophrenia: Causes, Symptoms and Treatment

We all have mood swings but not all mood swings have the same intensity. People who have extreme mood swings ranging from depression to manic highs are said to be suffering from bipolar disorder. These extreme moods are known as episodes and usually, last for a few days or even a few weeks. A person suffering from bipolar disorder could have an episode several times a year. This is a very common psychological problem and can affect both children and adults. Though it cannot be cured, this disease can be managed with medication.

There are no known causes for bipolar disorder but genetics may play an important role in triggering Bipolar Disorder. Hence, if a parent or sibling suffers from this condition, you have a risk of developing it as well. An imbalance in the neurotransmitters in the brain may also play a part in the development of this condition. Stress or traumatic events like the loss of a loved one can also increase your risk of suffering from this condition. Given that mood swings affect almost each one of us, bipolar disorder can be difficult to diagnose. Some of the things to look out for are:

Change in self-esteem
Unusual talkativeness or quietness
Being increasingly prone to distractions
Decreased need for sleep
Agitation
Recklessness in terms of spending decisions, relationships etc
It must be kept in mind that a person must display at least 4 of the above symptoms simultaneously to be diagnosed as bipolar. Also, none of these symptoms should be a result or side effect of any kind of medication, drugs, alcohol or other intoxicants.

There are four main types of bipolar disorder:

Bipolar I: In such cases, the person has at least one episode of elevated moods and associated abnormal behaviour in his or her life. This may be preceded or followed by depressive episodes.
Bipolar II: In these cases, the person must have suffered from at least one depressive episode. It is very similar to bipolar I except that in bipolar II the highs never reach the manic stage.
Rapid Cycling: Some people can have 4 or more manic and depressive episodes a year. In such cases, they are said to be rapid cycling. This condition affects 10-20% of bipolar cases.
Mixed Bipolar: Usually, bipolar patients show mood swings that alternate between manic and depressive moods. However, sometimes a person may experience both elation and depression simultaneously or in rapid succession of each other. These cases are known as mixed bipolar.
Once diagnosed, bipolar disorder can be managed with a combination of medication and psychotherapy. In some cases, electroconvulsive therapy may also be needed.

All About Bipolar Disorder

According to most experts, depression and diabetes have been intricately connected in a vicious cycle. While the prolonged and sustaining nature of diabetes directly makes one vulnerable to the bouts of depression, doctors tend to locate traces of depression in the family history of an individual in order to diagnose the roots of diabetes. It won't be too far-fetched to state that both causes as well as affects the other.

If you have diabetes, either type 1 or type 2, you have an increased risk of developing depression. And if you're depressed, you may have a greater chance of developing type 2 diabetes. The good news is that diabetes and depression can be treated together. And effectively managing one can have a positive effect on the other.

How diabetes and depression correlated? 
There are myriad ways in which diabetes affects depression and vice versa. 

Firstly, tackling such a long drawn disease and its various pitfalls might cause a lot of anxiety to one and lead to depression. Whereas on the other hand, depression reduces the zeal to live and thus results in poor lifestyle choices which in turn causes weight gain, unhealthy food habits, physical inactivity. As we are well aware, all these have the potential to wreak havoc for any patient of diabetes. 

Similarly, diabetes ushers in various other health complications, adversely impacting one's productivity. This may cause depression in a lot of people. 

On the flipside, depression impedes one's ability and enthusiasm to work or communicate, this in turn intervenes with one's monitoring of diabetes. Since these two extremely malevolent diseases have such close connections, medical science recommends ways to grapple with both. The rigors of managing diabetes can be stressful and lead to symptoms of depression.

Diabetes can cause complications and health problems that may worsen symptoms of depression.

Depression affects your ability to perform tasks, communicate and think clearly. This can interfere with your ability to successfully manage diabetes.

Treatment

Depression is just like any other illness, it can be treated. Treatment can lift the depression and improve diabetes control.

Looking after your diabetes will help decrease the risk of getting depression. If you already have depression, good diabetes management will help lessen the negative impacts it can have. Depression is no different to any of the other complication of diabetes. It is a genuine illness for which you need to seek help and support from health professionals.

The treatment for depression and diabetes involves a coordinated approach that monitors both diabetes control and the symptoms of depression. It is about finding the treatment that works best for each person. For example, people with diabetes and mild depression may find that regular physical activity improves depressed moods and also helps control blood glucose levels.

Helping yourself.

If you suspect you might have depression, take control of your health by:

Going to a doctor or other health professional
Getting involved in social activities
Engaging in regular moderate physical activity
Learning about depression and diabetes
Very particular about medicines prescribed for diabetes
Eating healthily and including a wide variety of nutritious foods
Achieving and maintaining healthy weight
Limiting your alcohol intake
Getting help, support and encouragement from family and friends
Asking your doctor to check your blood pressure, cholesterol and blood glucose levels.

Diabetes and Depression

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