The inflammation of the kidneys as an effect of Systemic Lupus Erythematosus (SLE) is known as Lupus Nephritis. Like lupus, this is an autoimmune disease. Inflammation of the kidneys hinders kidney functioning by not allowing the kidneys to regulate the optimum amount and types of fluids in the body and restricts the removal of waste through urine. It can also cause the protein to leak out of the kidneys. If not managed in time, this can eventually lead to kidney failure by scarring the kidney tissue. However, this is a rare occurrence. 

On an average, 6 out of 10 lupus patients suffer from lupus nephritis. In most cases, this disease develops within the first five years of lupus symptoms making their appearance. The symptoms of this disease are mild and can vary from person to person. Very often, the first signs of lupus nephritis become visible only in lab tests as the symptoms are similar to those exhibited by other kidney diseases. 

Some of the common symptoms of this condition are: 

Swelling of the feet, ankles and calves 
High blood pressure 
Weight gain 
Frothy, dark urine 
There are five stages types of this disease and hence, the first step to treating this disease is to identify its type. For this, your doctor will begin with a thorough physical examination and understand your medical history. He or she will also ask for a few tests including urine tests, blood tests, an ultrasound and a kidney biopsy to confirm the diagnosis. 

Lupus nephritis is usually treated with corticosteroids and immunosuppressive drugs. Medication may also be prescribed to lower blood pressure and prevent the clotting of blood. However, in some cases, this treatment may not be enough to stop the progression of the disease and some kidney function may be lost. If both kidneys fail, dialysis is the next medical step. This involves the use of a machine in place of the kidneys to filter and removes waste products from the body. This may be followed by the need for a kidney transplant. 

Since lupus patients are at a high risk of lupus nephritis, here are a few conscious lifestyle changes that can help prevent this condition:

Have a diet that is low in salt 
Avoid smoking and alcohol 
Exercise regularly 
Avoid non-steroid anti-inflammatory drugs("pain killers") and unproven alternative medications that can affect the kidneys.

What Is Lupus Nephritis?

Soft growth occurring on the genitals are known as Genital Warts. Genital warts are infections that are transmitted through physical intimacy (STI). These are caused by certain behaviours of the human papillomavirus (HPV). These growths on the skin cause discomfort, pain and itching. They are particularly harmful for women since certain types of HPV might also cause cancer of the vulva and cervix. HPV is one of the most common sexually transmitted diseases. Due to this, sexually active people are most vulnerable to various health complications, including genital warts. Prevention of this infection requires essential protection and treatment.

Symptoms:

Transmission of genital warts occurs through sexual activity. Development of warts occurs several weeks after the infection. Sometimes, it is not possible to view them with the naked eye. The top of the growths might resemble a cauliflower and might feel slightly bumpy or smooth while touching. The person who is infected may have a single wart or a cluster of warts.

In males, the genital warts may appear in the following regions.

Groin
Scrotum
Penis
Thighs
Inside or around the anus
In females, they might occur in:

Cervix
Outside the vagina or anus
Inside the vagina or anus
In a case where the person has had oral sexual contact with the infected person, the genital warts might appear on the mouth, lips, throat or tongue of the person. In case the genital warts are not visible, the other related symptoms include:

Itching
Vaginal Discharge
Bleeding
Burning
Treatment

Even though the genital warts disappear with time, it is not possible to eliminate the virus once it is in the bloodstream. This would result in several outbreaks during the entire course of life. This is a vital reason why the symptoms should be managed so that transmission of the disease is prevented. Treatment is possible only for relieving symptoms that are painful or for minimizing their appearance. Some topical wart treatments prescribed by the doctor may include:

Podofilox and Podophyllin (Condylox)
Trichloroacetic Acid (TCA)
Imiquimod (Aldara)
Some surgeries that the physician might conduct to remove genital warts that do not disappear with time include:

Interferon injections
Laser treatments
Cryosurgery, or freezing warts
Electrocautery, or burning warts with electric currents
Excision, or cutting off warts
Periodic Pap smears after the initial treatment is recommended for women with genital warts to monitor changes in the cervix.

Genital Warts - Can They be Treated? 

4 Types of Life-Threatening Rashes

Rashes are common skin problems but shouldn't be taken casually at all. Although most rashes are mild and do not create much problem, some might turn grow to become life-threatening.

These are:

1. Stevens-Johnson syndrome (SJS)

This skin rash is the result of a severe allergic reaction to medication. The condition affects the skin and mucous membranes. Various medicines, such as nonsteroidal anti-inflammatory drugs, anticonvulsants, penicillin, and sulphonamides might trigger this type of rash. It is characterized by painful lesions emerging in clusters.

2. Staphylococcal scalded skin syndrome (SSSS)

Mostly affecting babies and young children under the age of five, this skin disease brings on extensive blisters with red skin that looks burnt or scalded. This syndrome is caused by infection with strains of Staphylococcus bacteria.

3. Pemphigus Vulgaris (PV)

This unusual autoimmune skin condition gives rise to excruciating blisters on the skin, which often go on to the mouth, throat, nose and even genitals. The open sores from this disease often lead to infections and acute cases can even cause lung infections and lesions. This rash has no cure but is often treated with corticosteroids, antibiotics or immunosuppressants. If untreated, it can even cause death.

4. Toxic shock syndrome (TSS)

TSS is often caused by an overgrowth of Staphylococcus bacteria with the infection spreading throughout the body. Besides these bacteria, infections from surgical wounds contaminated nasal packing after nasal surgery and infections after baby birth are probable causes. This life-threatening rash generally affects teens and young adults, most of them being women. It can affect mucus membranes of mouth and eyes although there are no blisters or skin bumps. One can experience slight dizziness and high fever as well as swelling of the joints and eyelids. This skin condition often affects the liver, kidneys, the heart, and the brain.

Apart from these, there are several other types of skin infections, which can be equally discomforting and critical. Toxic epidermal necrolysis, dermatitis herpetiformis, Ehlers-Danlos Syndrome, Toxic Epidermal Necrolysis and several other nasty skin diseases are cases in point.



4 Types of Life-Threatening Rashes

Vitiligo is a condition in which white patches appear on the skin. It can affect any part of the body. It can affect the inside of the mouth and the hair as well. It happens when the skin cells (melanocytes) that make or produce pigment (colour) of the skin die or stop functioning. This disease is not contagious or life-threatening, it cannot be caught from another person having vitiligo. All types of skin can be affected by vitiligo but it may be more evident in people with darker skin. It develops between the ages 10 to 30 and it often appears before the age of 40.

Causes

The main cause of this disorder is still not clear, why the cells die or fail. For some reason, the colour or pigment-forming cells called melanocytes dies. However, these are the following reasons that can cause this problem:

An autoimmune disorder, where the defences of the body turn on their own cells instead of attacking the germs that destroyed the melanocytes

A trigger or stressful events such as exposure to industrial chemicals, stress, or sunburn

Family history (heredity)

A neural cause

A virus

A genetic oxidative stress imbalance

Symptoms

The one and only symptom of this condition is the appearance of white patches or flat white spots on the skin. Those white patches are irregular in shape. They may stay the same for a while but may get bigger with time on different parts of the body. It generally affects body folds such as armpits, around body openings, or around moles. It can also affect hair and eyelids. It does not cause any irritation, dryness, discomfort, or soreness in the skin.

Treatment

There is no known way to cure or prevent the condition but the appearance of the affected skin can be improved with corticosteroid creams and cosmetics. The doctor can recommend melanocyte transplant surgery which includes a new needling micro-grafting technique. The surgery includes a split-thickness skin graft that is taken from the normal area. Later, it is cut into very small pieces in diameter ranging from 0.1 mm-0.3 mm. The local anesthesia is given to the recipient area to implant the micro-grafts into the dermis by using the needling technique. This new method of treating this condition delivers satisfactory and rapid pigmentation.

Takeaway

Vitiligo is a disorder in which flat white spots or patches appear and can affect any area of the body. It happens when the melanocytes die or stop functioning. The condition can be managed by cosmetics, corticosteroid creams, therapies, and surgeries. Out of all these methods, melanocyte transplant surgery is a new and effective technique to manage this disease. However, it is always advisable to consult a doctor before opting for any of these methods. 

Vitiligo - Its Causes, Symptoms And Treatments!

Oily skin and summers: what is the ideal way to handle it?

Oily skin is a condition that can be characterized by shine on the skin and a large number of pores. The oil in question is a result of overactive sebaceous glands that produce excessive sebum. This can result in acne and blackheads. Summer is a time of the year where skin problems due to oily skin are worsened by factors such as sweat and dust. So proper skin care is necessary in order to negate the effects of oily skin.

There are multiple ways to handle this condition in summers:

1. Using cleansers - Proper cleaning of skin is a very important step in lessening the effects of oily skin. Harsh cleansers have an opposing effect as they facilitate secretion of oil, so a mild cleanser is usually the best option. Some cleansers may contain ingredients that irritate the skin, so care is advised in selecting a proper one.

2. Hydration and food - Keeping the body well hydrated in summers combined with a diet free of greasy, oily food and less fats can help in reducing the effects of oily skin.

3. Using masks to clear the face - Masks such as clay masks, yogurt, and baking soda can help in cleansing the skin by clearing the oil. It should be noted that these treatments should not be overdone as they can cause the skin to dry up too much and over secrete oil.

4. Skin moisturizers - People often have this notion that oily skin does not require moisturizer application. Selecting a moisturizer that is fit for oily skin and using it will help moisturize the skin and keep it healthy.

5. Sunscreen - Sunscreen is a necessity during summers, and the sunscreen you choose should be specifically for oily skin in order for it to work effectively. Application of sunscreen can help prevent the UV rays of the sun from penetrating the skin and cause complications.

6. Dermatological treatment - In case of severe oiliness, treatments such as chemical peels and creams laced with tretinoin can help.



Oily skin and summers: what is the ideal way to handle it?

If stressed, consuming certain food and medications can trigger skin rashes. This kind of rash is called hives. It is also known as urticaria. Anyone can be affected by hives, at least 20% of people are affected by hives at some time or the other in their lives. The itching could be severe or mild. It starts as a patch of scaly white skin that develops into red welts over time. To make sure the itching does not worsen, scratching, emotional stress, alcoholic drinks and exercise should be avoided.

Symptoms
1. Itchy bumps that are raised and are either red or flesh coloured
2. If the hive is pressed in the middle, the skin whitens this symptom is called blanching.
3. The hive formation can appear anywhere, disappear and then reappear somewhere else.

Common Triggers
1. Certain food like shellfish, eggs, peanuts and other nuts
2. Certain medicines like antibiotics, ibuprofen and aspirin
3. Insect bites or stings
4. Physical causes like pressure, sun exposure, cold, exercise and heat
5. Latex
6. Blood transfusions
7. Bacterial infections
8. Pet allergens
9. Viral infections like the common cold, hepatitis and infectious mononucleosis
10. Certain plants like poison ivy and poison oak
11. Pollen

Treatment
There is no distinct cure for hives. But you can control its symptoms in the following ways:
1. Antihistamines help in blocking histamines, which cause the allergy symptoms. Non sedating or low sedating Antihistamines will be mostly recommended by your doctor.
2. If episodes of hives are several, it may require limited treatment with prednisone. Prednisone will be able to lessen the symptoms.
3. If the symptoms get severe enough so much so that it swells up your tongue and you have problem breathing, then the doctor might prescribe an epinephrine. However, these symptoms can mean another thing, an anaphylaxis shock. Epinephrine is the only treatment for an anaphylaxis shock.

Prevention
If what caused hives to break out is figured out, then measures should be taken to avoid or eliminate the triggers.
1. Avoid eating food items that triggered the symptoms in the first place
2. If harsh soaps, frequent bathing cause hives, they should be avoided
3. Tight clothing should be avoided
4. If cold triggers hives, then wear warm clothing, wrap a scarf and do not swim in cold water.
5. Avoid sun exposure and wear sunblock
6. If a specific medication is causing the hives, inform your doctor.

All About Hives

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