The three primary functions of the kidney are- eliminating waste materials and toxins from the body, producing hormones that help control your body mechanism and regulating blood pressure. Chronic Renal Failure, also known as Chronic Kidney Disease, refers to the condition where your kidney gradually stops functioning properly over time- weeks, months or years. As the condition worsens, wastes and fluids start to build up in your system instead of being filtered out. This leads to an end-stage renal failure/disease.

What causes Chronic Renal Failure?
Chronic renal failure is caused due to a condition or disease that impairs kidney function. The most common causes are- diabetes (Type 1 and Type 2), polycystic kidney disease, glomerulonephritis, interstitial nephritis. Glomerulonephritis occurs when the filtering units of the kidney become, inflamed. Interstitial nephritis refers to an inflammation in the kidney tubules and its surrounding regions. Prolonged obstruction of the urinary tract due to kidney stones or enlarged prostate, also can cause chronic renal failure.

What are the symptoms that you must watch out for?
Symptoms and signs of chronic renal failure develop gradually over time. Therefore, most of the time people suffering from this condition are diagnosed at the later stage when functioning of the kidney is significantly impaired. Nevertheless, if you encounter signs such as unintentional weight loss, weakness and fatigue, vomiting and nausea, swelling of face and legs, cramps and muscle twitches, change in the urinating pattern, easy bruising, blood in the stools etc., then you should see a doctor and have yourself diagnosed. In case the fluids get accumulated in the lining of your heart or lungs, you may experience chest pain and shortness of breath.

Role of homeopathy in curing Chronic Renal Failure-
Unlike conventional treatment methods which focus on the pathological condition, homeopathy takes a holistic approach to treat the individual. Homeopathy remedies and medicines are natural, and try to rectify the underlying causes of this condition. The medications are selected and prescribed after thorough analysis of the patient s medical history and health condition. A particular remedy is chosen keeping in mind the general symptoms of the condition. Among several homeopathic medicines, the frequently used ones are- Belladonna and a solution made from gold and sodium. Homeopathy remedies reduce swelling of the face, cures kidney inflammations, and reduce severe, recurring pain in the lumbar region. They work by stimulating your immune system so that the damaged kidney and other organs start functioning more correctly.

Homeopathy remedies do not provide substitutes for any organ of your body. They simply repair the damaged organs, improve your overall health and thereby prevent the person from suffering a relapse.

Chronic Renal Failure - How Homeopathic Treatment Is Best For You?

Colorectal cancer is otherwise known as cancer of the colon or the rectum. This can affect both men and women with age being a major risk factor. Majority of such cancers are seen to occur after age of 50 years.

Type: colorectal cancers can present as one of the following types: 

Adenocarcinomas are the most common type of colorectal cancers. These cancers begin in the cells making mucous and other fluids. Certain colorectal cancers begin as adenomatous polyps (adenomas) that turn cancerous over a period of time. This is precisely why the adenomas are regarded as pre-cancerous or pre-malignant.

Gastrointestinal (GI) carcinoid tumors, GI stromal tumors, primary colorectal lymphoma, leiomyosarcoma, melanoma & squamous cell carcinoma are certain other colorectal cancers

Carcinoid tumors: start in specialized cells that produce hormones, in the intestine.

GI Stromal tumors: start in the interstitial cells of Cajal (ICC), in the wall of the colon.

Lymphomas: start typically in the lymph nodes but they may also start in colon or rectum.

Sarcomas: can start in the muscle and the connective tissue in the walls of the colon and rectum.

Gender: it affects both male and female populace.

Etiology: mostly, the factors that are associated with increased risk of colorectal cancer include the following  

Age exceeding 50 years.

Racial & ethnic background such as African Americans, in the USA, are known to have the highest incidence of colorectal cancer, and mortality rates.

Low fibre and high fat diet. Excessive consumption of red meat (e.g. goat meat, beef, pork, lamb, or liver), processed meats, butter, refined grains, sweets, sugary drinks etc all can increase the risk of colorectal cancer.

Personal history of inflammatory bowel disease (IBD) (e.g. ulcerative colitis), Crohn s disease, adenomatous colorectal polyps, colorectal cancer etc all.

Family history of colorectal cancer or adenomatous polyps etc all.

Inherited syndromes such as familial adenomatous polyposis (FAP) and Lynch syndrome (hereditary non-polyposis colon cancer or HNPCC).

Sedentary lifestyle/ associated Obesity.

Type 2 diabetes.

Tobacco and alcohol abuse.

Features or symptoms can vary from person to person depending on the size and location of the tumour. Following are the signs & symptoms mainly -

Changes in bowel habits, diarrhea or constipation or an alternating diarrhea and constipation.

Occult/ blood in the stool, and 

Problems related to blood loss (e.g. anemia, weakness, fatigue, intolerance to exercise, shortness of breath, increased heart rate, chest pain etc all),

Abdominal discomfort (frequent gas/ flatulence, bloating, fullness, cramps, and pain), vomiting etc.

Unexplained weight loss,

Pain with bowel movement,

Feeling that bowel does not empty completely,

Stools are narrower than usual.

Diagnosis: Following are the diagnostics employed. Abnormal blood test results may be indicative of malignancy, but a follow-up imaging/ biopsy is always the gold standard for accurate diagnosis.
Blood: fecal occult blood test, Carcinoembryonic Antigen (CEA) assay values are raised, Hb/ RBC counts may be low.
Imaging: Colonoscopy, Endorectal Scan/ CT Scan followed by Biopsy clinches the diagnosis and the nature of the disease.
Apart from the above-mentioned barium enema X-Ray, USG, Chest X-ray, PET CT scan etc all help detect metastasis, if any. An increase in level of the serum tumor marker  CEA  is indicative of metastatic spread/ proliferation that can be ascertained through a PET CT scan.
Treatment: Conventional treatment includes surgery, radiation and chemotherapy as contextually appropriate. Simultaneously, an adjunctive/ integrative naturopathic treatment with suitable complementary & alternative medicines (CAM)/ therapies too can help improve clinical outcomes and facilitate recovery as feasible contextually.
Prognosis: preventive measures, earlier diagnosis and right early treatment is key for better prognosis and efficient/ effective therapeutic management. Usually, the chances of cure for an early stage cancer are more. Above-mentioned apart, recovery chances are influenced by the grade, stage of cancer, recurrence and the patient s general health & vitality etc all too.

Prevention: rightly said, prevention is always a better choice. Although genetic risks are difficult to modify, still an adherence to a Mediterranean diet, maintaining an ideal body weight and an active lifestyle with due emphasis on regular exercising (for at least 30 minutes daily), de-stressing and relaxation is highly recommended for prevention or reducing the risks of colorectal cancer. A healthy eating plate comprises essentially a low fat diet, fibre rich foods including whole grain cereals, green leafy vegetables cooked using healthy vegetable oils, fresh fruits of all colours as seasonally available and healthy proteins/ fats including fresh fish, poultry, beans, nuts etc all. It is advisable to limit milk/ dairy, preferably of low fat content, to 1 to 2 servings max daily. Although alcohol is optional and is not for everyone, the consumption of the same, if any, has to be strictly in moderation, and is best avoided. Smoking is to be avoided as well. Again, red meat, butter, refined grains, sweets, sugary drinks including carbonated beverages and other high calorie foods etc all, if any, are to be taken sparingly or are best avoided too. Apart from the generic preventive measures as mentioned above, certain pre-malignant conditions, of which adenomas are the most common, can be successfully treated with complementary and alternative medicines too.

Colorectal Cancer - In a Nutshell!

The spleen is a very important organ of the human body. A splenectomy is the process of removing the spleen from the human body. The spleen is a very small, fist-sized organ which is located under the rib cage, close to the stomach. The basic function of the spleen is removing the damaged or dead red blood cells. It also removes any kind of bacteria present in the bloodstream that can cause infections. When the spleen is removed, there are chances of infection that can be life-threatening if not treated. It is always better to prevent infections as soon as you see the symptoms.

Why do you need a Splenectomy?
There can be many reasons for the removal of the spleen from your body such as  

In case, the spleen is damaged due to an accident, injury or in the process of an abdomen surgery.
For treating some medical conditions such as lymphomas or leukemias.
Overactivity of your spleen.
In case any abnormalities found in the red blood cells of the body.
Collagen vascular diseases
In some rare cases, a person may be born without a spleen.
Sepsis:
The infection that is caused due to the removal of the spleen is called sepsis. This is a life-threatening condition where the bacteria that causes the infection keeps on spreading to the entire body and bloodstream. It is going to impact the normal functioning of the human body. Symptoms of sepsis include high fever, shivering, headache, confusion, drowsiness, severe pain in the abdominal area and increased heartbeat. But all this starts with a simple respiratory problem such as a respiratory tract infection.

Tips to prevent infections after a Splenectomy:
If you have had a splenectomy, then it is very important for you to take certain precautions such as:

You need to take certain vaccines such as HIB, pneumococcal or meningococcal and they will reduce the risk of getting an infection after the removal of the spleen.
You will have to take some additional doses of the above vaccines in order to maintain the effect on your body.
You need to take antibiotics on a daily basis to prevent a sepsis infection.
The first stage or symptoms start with chills or fever and hence you should make sure to maintain a set of antibiotics. Start taking them as soon as you see these symptoms.
If you are travelling to another country, then make sure you carry the antibiotics with you. If you notice any kind of symptoms, you need to take the medicine immediately.
You need to discuss the above-listed points with your doctor, especially if you require more information about how to prevent infection after the spleen is removed.

Tips To Prevent Infections After A Splenectomy!

The tube that carries food to your stomach from your throat is called the oesophagus. When the muscular valve (lower oesophagus sphincter) in the oesophagus fails to relax and carry the food to the stomach, the condition is termed as achalasia.

Achalasia has a variety of causes, and can be difficult for your doctor to diagnose the exact cause. Some common causes of Achalasia include:
1. Hereditary predispositions
2. Autoimmune disorders (The immune system erroneously destroys healthy cells in the body)
3. Nerve degeneration in the oesophagus
There other medical conditions that often lead to symptoms identical to achalasia, such as oesophageal cancer and Chagas  disease (an infectious disease caused by a parasite).

Other symptoms of achalasia include:

The most prominent symptom of achalasia is dysphagia, which is characterised by swallowing difficulties or sensations of food stuck in the oesophagus. Dysphagia often triggers coughing and shortness of breath or choking on food.
1. Discomfort or pain in the chest
2. Weight loss
3. Heartburn
4. Intense discomfort or pain after eating

Some of the treatments include:

Most of the methods to treat achalasia focus on the lower oesophageal sphincter (LES). The treatments used can either permanently alter the sphincter s function, or reduce symptoms.
1. Oral medications such as calcium channel blockers or nitrates are prescribed, which can relax the LES to let food pass through with more ease. Your doctor may also treat the LES with Botox.
2. For a more permanent treatment, the sphincter can be dilated or altered. In dilation, a balloon is inserted into the oesophagus and it is inflated. This will stretch out your oesophagus to improve function.
3. To alter the oesophagus, oesophagomyotomy is performed. It is a kind of surgery where minimal incisions are made to gain access to the LES, and then it is carefully altered to improve flow of food to the stomach.

Unlike dilation, which can cause complications such as tears in the oesophagus, oesophagomyotomy has a greater success rate. However, certain complications may still arise, such as:
1. Acid reflux
2. Respiratory conditions that are caused by food entering your windpipe

Achalasia - Can Autoimmune Disorders be the Cause Behind it

Gastroesophageal reflux disease (GERD) is also called as acid reflux. It is a long-term digestive disorder that affects the lower esophageal sphincter, the ring of muscle between the esophagus and stomach which causes the stomach contents to come back up into the esophagus resulting in either symptoms or complications. Gastroesophageal reflux disease is mild acid reflux that occurs at least twice a week or moderate-to-severe acid reflux which occurs at least once a week.

Epidemiology

In western populations, GERD affects approximately 10% to 20% of the population and 0.4% newly develop the condition. In developed nations, the prevalence rate of GERD is associated with age; with adults aged 60 to 70 being the most commonly affected.

Signs and Symptoms

Esophageal symptoms include:

Heartburn
Regurgitation of food or sour liquid
Dysphagia
Sensation of a lump in the throat
Extraesophageal symptoms include:

Coughing and/or wheezing
Hoarseness, sore throat, or 
Otitis media
Noncardiac chest pain
Enamel erosion or other dental manifestations
New or worsening asthma
Disrupted sleep
Risk Factors

Obesity
Pregnancy
Hiatus hernia
Scleroderma and systemic sclerosis
The use of medicines such as prednisolone 
Delayed stomach emptying Zollinger-Ellison syndrome which can show an increase in gastric acidity because of gastrin production
A high blood calcium level which can increase gastrin production, leading to increased acidity
Visceroptosis or Gl nard syndrome, in which the stomach has sunk in the abdomen upsetting the motility and acid secretion of the stomach.
Factors that can increase acid reflux involve:

Smoking habit
Eating heavy meals or eating late at night
Eating fatty or fried foods
Drinking certain beverages, such as alcohol or coffee
Medications, such as aspirin
Tight clothes
Increased intra-abdominal pressure
Differential Diagnosis

Heart disease causing chest pain
Laryngopharyngeal reflux OR extraesophageal reflux disease
Infection
Peptic ulcer
Esophageal spasm
Complications

Narrowing of the esophagus (esophageal stricture): Stomach acid causes the formation of a scar tissue which narrows the food pathway.
An open sore in the esophagus (esophageal ulcer): Acid causes an open sore which bleeds, causes pain, and makes swallowing difficult.
Precancerous changes in the esophagus (Barrett's esophagus): Damage from acid can cause changes in the tissue lining the lower esophagus
Anemia
How to arrive at the diagnosis?

Upper gastrointestinal endoscopy/esophagogastroduodenoscopy
Esophageal manometry
Ambulatory 24-hour pH monitoring
Treatment

The goals of treatment are controlling symptoms, healing esophagitis, and prevention of recurrent esophagitis or other complications. Lifestyle modifications include the following:

Losing weight (if overweight)
Eating small and frequent meals instead of large meals
Waiting 3 hours after a meal to lie down
Elevating the head end of the bed by 8 inches
Avoiding bending or stooping positions
Medications

H2 receptor antagonists (ranitidine, cimetidine)
Proton pump inhibitors (omeprazole, pantoprazole)
Prokinetic agents (aluminum hydroxide)
Antacids (magnesium hydroxide)
Surgery

Transthoracic and transabdominal fundoplication
Placement of a device to augment the lower esophageal sphincter

Gastroesophageal Reflux Disease - What Causes It?

Kidney transplant surgery is a surgical procedure where a healthy kidney is used to substitute a diseased one. The healthy kidney is obtained from either a deceased donor or a family member who has a good blood type match with the recipient. Usually, the recipient receives one kidney if the donor is alive and/or both the kidneys from a deceased donor.

Certain reasons for going for a kidney transplant surgery might include:
1. Kidney failure due to diabetes
2. Infections in the urinary tract
3. Autoimmune disorders such as lupus (an autoimmune disorder)
4. Polycystic kidney disorders
5. Obstructions in the kidney
6. Glomerulonephritis, where inflammation occurs in the kidney

Preparation for the surgery
Before the procedure, certain tests are carried out to determine your suitability for the procedure. The tests start with a psychological evaluation followed by blood tests and diagnostic tests to check for health problems. Once the tests are done, you will be placed on the waiting list for kidney recipients. Once the donor is available, you will be asked to get ready for the surgery.

Procedure: The procedure begins with you being administered general anesthesia. An incision is made in the lower part of the stomach, through which the donated kidney is inserted in the body. The next step involves attaching adjacent blood vessels to the kidney so that it has a proper supply of blood. Finally, the ureter of the kidney is linked with the bladder, facilitating normal disposal of bodily wastes. A plastic tube, known as a stent, is placed in the ureter to facilitate urine flow. This is later removed by a procedure called cystoscopy. Once the surgery is completed, the incision is closed by stitches.

Aftercare: After the procedure is completed, you will be given painkillers to ease the pain. Immunosuppressant medications will be prescribed to prevent your immune system from destroying the cells of the donated kidney. Usually, the duration of stay at the hospital post-surgery is about a week. 

Kidney Transplant Surgery and What You Should Know About It

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