The body has multiple chemicals called hormones, which regulate many of its functions. Increased or decreased levels of these hormones affect various functions including metabolism, growth and sexual functions. Thyroxin produced by the thyroid (situated in the front of the neck) is one such hormone, which has a significant role to play in metabolism.

Graves  disease is one of the main causes of hyperthyroidism, where there is excessive production of thyroid hormones. Graves  disease is an autoimmune disorder, wherein the body reacts against its own tissues. It is very common in women than men, especially after 20 years of age. Family history also has a strong correlation in developing Graves  disease. The high levels of thyroid hormone increase the rate of metabolism, thereby altering weight, mental energy levels, physical stamina, and also mood.

Thyroid hormone is related to metabolism and more amount of it lead to higher metabolism. This causes the following symptoms.

    Intolerance to heat
    Excessive sweating
    Nervousness and anxiety
    Inability sleep, as the mind is always excited
    Increased appetite (sometimes despite weight loss) due to higher metabolism
    Irregular menstrual cycles
    Palpitations (rapid, loud heartbeat)
    Irregular heartbeats (tachyarrhythmia)
    Fine tremors of the extended arms
    Breast enlargement in men, known as gynecomastia
    Extreme moodiness, causing irritability and anger
    Inability to focus and concentrate
    General fatigue and shortness of breath with any exertion
    Increased frequency of bowel movements

In addition, the eye symptoms are quite diagnostic including:

    Protrusion of the eyes (exophthalmos), giving an impression that they are going to fall out
    Double vision
    Excessive tearing
    Increased irritation in the eyes

Diagnosis: The first symptom would be the presence of an enlarged thyroid gland (front of the neck above the collarbone), and the some of the above symptoms would be present.
In addition, tests to check for thyroid gland functioning including T3 and T4 levels would reveal increased amounts of hormone in the blood stream.
As a confirmatory test, the radioactive iodine uptake test also is done, which will indicate increased uptake by the thyroid gland. This indicates that the gland is functioning at an increased pace and requires additional iodine for the production of thyroid hormones.

Treatment: There are two approaches to it, one to control the symptoms and the other to control the thyroid gland per se.

    Beta blockers are very useful in controlling rapid heart rate and anxiety.
    Prednisone may be used to control eye irritation and swelling
    Antithyroid drugs are used to control the production of thyroid
    Radioactive iodine is given orally to control excessive thyroid production
    In severe cases, thyroid gland may be surgically removed partially or completely

Graves  disease is not life-threatening and once symptoms are controlled, the patient s quality of life improves drastically.

Graves' Disease - Things You Should Know About It

Thyroid disorders are associated with the thyroid gland. A thyroid gland is a butterfly-shaped gland situated right at the base of one s neck. The role of the thyroid gland is to carry out numerous metabolic processes within the body. The brain regulates the functioning of the thyroid gland through a feedback mechanism. There are a number of disorders, both severe and trivial, which could affect the thyroid gland.

Main symptoms of thyroid disorders:

Weight loss and weight gain

Changes in heart rate (arrhythmia)

Hair loss

Frequent mood swings

Swollen neck

Sudden bouts of moderate to high fever

Other symptoms include:

Numbness or a tingling sensation in the hands

Constipation

Abnormalities or irregularities in menstruation

Brittle nails and dry skin

Blurred vision

Weakened muscle tone and frequent tremors in the body

Treatment Options:

Intake of thyroid hormone pills may prove beneficial. Once you start with the treatment, you may notice significant improvement within the first two or three weeks. Generally, once affected by thyroid disorders, one might have to be on these medications his/her entire life. Over time, this treatment procedure should result in lowering of the cholesterol levels, increased energy; but in certain cases, might throw up side effects in the form of sudden and unexplained weight loss.



Anti-thyroid medications help reduce and regulate the secretion of the thyroid hormone, thus treating certain thyroid disorders (such as hyperthyroidism).

Beta blockers are drugs help in reducing high blood pressure, heart palpitations and controlling heart rate.

In severe cases, such as enlargement of the thyroid gland, surgery is advised by the doctor, in which the thyroid gland is removed. Tumors or thyroid nodules are also treated by this surgical process.

In cases of thyroid cancer, besides the surgical procedure, radioactive iodine therapy (radioiodine) is recommended. This therapy helps destroy the thyroid gland and other thyroid (malignant) cells which may be taking up iodine. However, the side effects of this technique are minimal. This procedure helps to destroy those tissues which may not have been removed by the surgery. If the thyroid cancer has spread to the lymph nodes or to other parts within the body, this particular mode of treatment can be very effective.

Types of Thyroid Disorders:

Hypothyroidism: This is a condition characterized by an underactive thyroid gland. In this case, sufficient thyroid hormone is not secreted in the body.

Hyperthyroidism: This is characterized by an overactive thyroid gland, that results in overproduction of the thyroid hormone.

Thyroid cancer: It is a type of cancer of the thyroid gland.

Goiter: This is a disorder wherein the thyroid gland gets abnormally enlarged.

Thyroid nodules: This is marked by swelling of the thyroid gland. If you wish to discuss about any specific problem, you can consult a endocrinologist and ask a free question.

Thyroid Disorders: Symptoms, Treatment and Types

Thyroid disorders are conditions that affect the thyroid gland, which is a butterfly-shaped gland in front of the neck. There are specific kinds of thyroid disorders that include:

Hypothyroidism
Hyperthyroidism
Goiter
Thyroid Nodules
Thyroid Cancer
Epidemiology, Incidence, and Prevalence
It has been estimated that about 42 million people in India suffer from thyroid diseases.

Hypothyroidism

Hypothyroidism occurs when the thyroid gland produces an insufficient amount of thyroid hormone. It can develop from problems within the thyroid gland, pituitary gland, or hypothalamus. 

Symptoms of hypothyroidism can include:

Fatigue
Poor concentration or feeling mentally "foggy"
Dry skin
Constipation
Feeling cold
Fluid retention
Muscle and joint aches
Depression
Prolonged or excessive menstrual bleeding in women
Common Causes of Hypothyroidism

Hashimoto's thyroiditis (an autoimmune condition that causes inflammation of the thyroid gland)
Thyroid hormone resistance
Other types involving inflammation of the thyroid, such as acute thyroiditis and postpartum thyroiditis
Hyperthyroidism

Hyperthyroidism refers to the excessive production of thyroid hormone, a less common condition than hypothyroidism. Symptoms of hyperthyroidism are usually related to increased metabolism. In mild cases, there may not be apparent symptoms.

Signs and symptoms of hyperthyroidism can include:

Tremors
Nervousness
Fast heart rate
Fatigue
Intolerance for heat
Increase in bowel movements
Increased sweating 
Concentration problems
Unintentional weight loss
Common causes of hyperthyroidism

Graves' disease
Toxic multinodular goiter
Thyroid nodules that overexpress thyroid hormone (known as "hot" nodules) 
Abnormal secretion of TSH
Thyroiditis (inflammation of the thyroid gland)
Excessive iodine intake
Goiter: A goiter is an enlargement of the thyroid gland, regardless of cause. A goiter may be associated with hypothyroidism, hyperthyroidism, or a normal thyroid function. 

Thyroid Nodules: Nodules are lumps or abnormal masses in the thyroid. Nodules can be caused by benign cysts, benign tumors, or less commonly, by cancers of the thyroid. If nodules are excessively large, they may cause symptoms related to compression of nearby structures. 

Thyroid Cancer: Thyroid cancer is more common among adult women than men or youth. About 2/3rd of cases occur in people under age 55. There are different kinds of thyroid cancers depending upon the specific cell type within the thyroid that has become cancerous. Most cases of thyroid cancer have a good prognosis and high survival rates, especially when diagnosed in its early stages.

Investigations

Blood tests are done to measure levels of thyroid hormones. Blood tests are also done to identify antibodies against thyroid tissue, such as titers of antithyroglobulin, antithyroperoxidase, or TSH receptor-stimulating antibodies.

Treatment

Thyroid disorders can be treated with medications or, in some cases, surgery. The treatment will depend on the particular disease of the thyroid.Medications can be given to replace the missing thyroid hormone in hypothyroidism. Synthetic thyroid hormone is given in pill form by mouth. When hyperthyroidism is present, medications can be used to decrease the production of thyroid hormone or prevent its release from the gland. 

Thyroid Disorder - What All Should You Know 

Do you feel extremely tired many times in a day? Are you experiencing sudden weight gain, chills at night and hair loss? Is your neck a bit bloated up? If you are experiencing any of the mentioned symptoms, it might be that your body regulator- Thyroid- is unbalanced. Quick 3 tests can help you detect any abnormality - TSH, T3 and T4. Women were three times more likely to be affected by thyroid dysfunction than men. 1 in 10 adults in India suffers from hypothyroidism, with 50 per cent being women.

What is the thyroid gland?
The thyroid is a butterfly shaped gland in the front of the neck. It produces hormones that control the speed of your metabolism - the system that helps the body use energy. Thyroid disorders can slow down or rev up your metabolism by disrupting the production of thyroid hormones. When hormone levels become too low or too high, you may experience a wide range of symptoms.

What are the Symptoms?
Thyroid can be of 2 types - Hyper (Overactive) and Hypo (Underactive) Thyroid.
Low and Underactive Thyroid High and Overactive Thyroid
Fatigue Nervousness
Dry Skin & Hair Tremors - Hand Shaking
Brittle Hair Hair loss or thinning hair
Constipation Diarrhea
Low Pulse High Pulse
Weight Gain Weight loss without trying
Intolerance to cold temperature Intolerance to hot temperature
Depression Sweatiness
Swelling in lower part of neck Swelling in lower part of neck

The swelling in the neck is a major and most significant feature. Hence one should always do the Self Neck Test.

Who should be tested?
Women aged 35 and above or those with symptoms/risk factors/family history are the right candidates for screening. It has been estimated that 75% of the people suffering from thyroid are undiagnosed.

Diagnosing thyroid disorders - A simple blood test can provide an answer. TSH (Thyroid Stimulating Hormone) levels determine thyroid hypo and hyper function as it regulates the work of thyroid gland. Rarely an imaging study or biopsy is needed. Two additional tests may be required - T3 and T4.

What happens if Thyroid remains undetected?
As Thyroid disorders are hormonal imbalances, undetection can lead to a number of secondary complications:
Obesity
High Cholesterol and Hypertension
Hair Fall
Heart Disease
Complications in pregnancy

Understanding Thyroid Problems in Women: Did You Get the Test Done?

The thyroid hormones, namely T3, T4 and TSH (Thyroid Stimulating Hormone) play a pivotal role in various metabolic processes in the body. Any imbalance in the level of these hormones can interfere with the normal body functions. While an elevated level of the thyroid hormones gives rise to Hyperthyroidism, a reduced level of the same thyroid hormones can lead to a condition medically termed as Hypothyroidism. A proper diagnosis and treatment can bring about a significant improvement. However, there are some common mistakes that many people with thyroid problems often make.

Choose your diet with care: The health benefits of a balanced and nutritious diet are known to all. However, a food considered healthy may not be an ideal choice for a thyroid patient. Time and again, broccoli and kale have been recommended for its nutritive value. However, these vegetables may not be a good choice for thyroid health. Known to contain goitrogens, they may interfere with the production of the thyroid hormones. Gluten, a protein present in wheat, rye, and barley, though healthy should be avoided, especially in the case of Hypothyroidism.
Obesity may not be the trigger: While it is a healthy practice to maintain a healthy body weight, it is unfair to blame the extra kilos for every single disease that you suffer from. Many people believe that losing weight is the best way to deal with thyroid problems. However, the fact is quite different from what you believe. Thyroid problems can be an outcome of various triggers where losing weight may provide negligible or no assistance to reverse or improve the condition. In fact, rapid weight loss may give rise to some complications which may aggravate the condition further.
Thyroid glands are not always at fault: Many people associate thyroid problems with some abnormalities or improper functioning of the thyroid glands. There is no denying the fact that problems in the thyroid glands often trigger thyroid disorders. However, this is not the only cause. A host of other factors such as stress, medical conditions, certain medications and unhealthy lifestyle habits may be equally responsible for the thyroid problems. In some cases, the body may fail to utilize the thyroid hormones produced by the thyroid glands. In another condition, the thyroid hormone produced is unable to enter the cell (triggered by a problem in the cell receptor). It is important to identify the root cause of the problem rather than generalizing.
People with hypothyroidism do not need to gulp down tons of iodine. Always use the amount recommended by the doctor. Increased intake of iodine supplements (way above the recommended quantity) may result in unnecessary health complications such as Wolff-Chaikoff effect.
Many health organizations or individuals may promise instant relief and cure. They may lure you with some irresistible offers. However, it will be foolish on your part to fall for such claims. Always seek the help of experienced and genuine health professionals.

Thyroid - 5 Common Mistakes That Most People Do!

When the thyroid gland is affected, leading to the thyroid disorder of an underactive nature, it is termed as hypothyroidism. The thyroid gland which is found in the lower portion of the neck is critical to the proper functioning of the human body s metabolism. In simple words, the thyroid hormone being released by this gland has to travel throughout the body to help in the use of energy gained from the food consumed and to keep the vital parameters such as the heartbeat in the right condition. When some antibodies attack the thyroid gland, and don t permit it to release adequate amounts of hormones into the system, the hypothyroid condition results.

The Causes for Hypothyroidism
An inflammation caused to the thyroid gland can result in this condition. This is an auto-immune disorder, in the sense that some internal factors can trigger this inflammation. Medically, the inflammation is termed  thyroiditis . There are also other factors that can cause hypothyroidism. These include radiation therapy. If the therapy has been administered near the neck area and the rays have penetrated to the thyroid gland, the inflammation can occur. Even those suffering from hyperthyroidism, the overactive form of thyroid and given radioactive iodine treatment can suffer from this condition due to the damage caused to the gland. Lastly, certain specific medications, if consumed regularly, can cause the condition.

Particular Sections of the Community at Risk
While there is no strict division among the population on vulnerability to be affected by hypothyroidism, research has indicated that women, and that too older women, may be more at risk. Men may be at a lower risk. Besides this, there are other profiles such as race and age which can also have a bearing on the level of risk. Of particular significance is that people who already suffer from autoimmune disorders are more likely to suffer from hypothyroidism than others.

Symptoms and Diagnosis
Many symptoms might not be unique to the hypothyroidism condition and can be misleading. Constipation, depression, hair loss and fatigue are some of them and an experienced medical practitioner will weigh the other factors, including the profiles explained above to reach the proper conclusion. The conventional TSH (thyroid-stimulating hormone) and T-4 (thyroxine) blood tests will be advised by the physician and the results should provide a reasonable confirmation of the condition. If doubts still persist an ultrasound or scan can also be ordered.

Hypothyroidism Treatment
As mentioned, for the body s metabolism to function normally, it is essential that the thyroid gland releases the thyroid hormone in sufficient quantities. Treatment of hypothyroidism is therefore very essential. The most frequently followed treatment is to prescribe regular intake of the synthetic thyroid hormone called T4. It is usually available in the form of a pill and has to be taken daily. The physician will know the concentration and dosage to be advised. Periodically testing your blood is necessary to monitor the levels.

Inflammation Of The Thyroid Gland - Can It Be Safely Controlled & Treated?

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