The body has multiple chemicals called hormones, which regulate many of its functions. Increased or decreased levels of these hormones affect various functions including metabolism, growth and sexual functions. Thyroxin produced by the thyroid (situated in the front of the neck) is one such hormone, which has a significant role to play in metabolism.

Graves  disease is one of the main causes of hyperthyroidism, where there is excessive production of thyroid hormones. Graves  disease is an autoimmune disorder, wherein the body reacts against its own tissues. It is very common in women than men, especially after 20 years of age. Family history also has a strong correlation in developing Graves  disease. The high levels of thyroid hormone increase the rate of metabolism, thereby altering weight, mental energy levels, physical stamina, and also mood.

Thyroid hormone is related to metabolism and more amount of it lead to higher metabolism. This causes the following symptoms.

    Intolerance to heat
    Excessive sweating
    Nervousness and anxiety
    Inability sleep, as the mind is always excited
    Increased appetite (sometimes despite weight loss) due to higher metabolism
    Irregular menstrual cycles
    Palpitations (rapid, loud heartbeat)
    Irregular heartbeats (tachyarrhythmia)
    Fine tremors of the extended arms
    Breast enlargement in men, known as gynecomastia
    Extreme moodiness, causing irritability and anger
    Inability to focus and concentrate
    General fatigue and shortness of breath with any exertion
    Increased frequency of bowel movements

In addition, the eye symptoms are quite diagnostic including:

    Protrusion of the eyes (exophthalmos), giving an impression that they are going to fall out
    Double vision
    Excessive tearing
    Increased irritation in the eyes

Diagnosis: The first symptom would be the presence of an enlarged thyroid gland (front of the neck above the collarbone), and the some of the above symptoms would be present.
In addition, tests to check for thyroid gland functioning including T3 and T4 levels would reveal increased amounts of hormone in the blood stream.
As a confirmatory test, the radioactive iodine uptake test also is done, which will indicate increased uptake by the thyroid gland. This indicates that the gland is functioning at an increased pace and requires additional iodine for the production of thyroid hormones.

Treatment: There are two approaches to it, one to control the symptoms and the other to control the thyroid gland per se.

    Beta blockers are very useful in controlling rapid heart rate and anxiety.
    Prednisone may be used to control eye irritation and swelling
    Antithyroid drugs are used to control the production of thyroid
    Radioactive iodine is given orally to control excessive thyroid production
    In severe cases, thyroid gland may be surgically removed partially or completely

Graves  disease is not life-threatening and once symptoms are controlled, the patient s quality of life improves drastically.

Graves' Disease - Things You Should Know About It

Do you feel extremely tired many times in a day? Are you experiencing sudden weight gain, chills at night and hair loss? Is your neck a bit bloated up? If you are experiencing any of the mentioned symptoms, it might be that your body regulator- Thyroid- is unbalanced. Quick 3 tests can help you detect any abnormality - TSH, T3 and T4. Women were three times more likely to be affected by thyroid dysfunction than men. 1 in 10 adults in India suffers from hypothyroidism, with 50 per cent being women.

What is the thyroid gland?
The thyroid is a butterfly shaped gland in the front of the neck. It produces hormones that control the speed of your metabolism - the system that helps the body use energy. Thyroid disorders can slow down or rev up your metabolism by disrupting the production of thyroid hormones. When hormone levels become too low or too high, you may experience a wide range of symptoms.

What are the Symptoms?
Thyroid can be of 2 types - Hyper (Overactive) and Hypo (Underactive) Thyroid.
Low and Underactive Thyroid High and Overactive Thyroid
Fatigue Nervousness
Dry Skin & Hair Tremors - Hand Shaking
Brittle Hair Hair loss or thinning hair
Constipation Diarrhea
Low Pulse High Pulse
Weight Gain Weight loss without trying
Intolerance to cold temperature Intolerance to hot temperature
Depression Sweatiness
Swelling in lower part of neck Swelling in lower part of neck

The swelling in the neck is a major and most significant feature. Hence one should always do the Self Neck Test.

Who should be tested?
Women aged 35 and above or those with symptoms/risk factors/family history are the right candidates for screening. It has been estimated that 75% of the people suffering from thyroid are undiagnosed.

Diagnosing thyroid disorders - A simple blood test can provide an answer. TSH (Thyroid Stimulating Hormone) levels determine thyroid hypo and hyper function as it regulates the work of thyroid gland. Rarely an imaging study or biopsy is needed. Two additional tests may be required - T3 and T4.

What happens if Thyroid remains undetected?
As Thyroid disorders are hormonal imbalances, undetection can lead to a number of secondary complications:
Obesity
High Cholesterol and Hypertension
Hair Fall
Heart Disease
Complications in pregnancy

Understanding Thyroid Problems in Women: Did You Get the Test Done?

The body is controlled by chemicals known as hormones. These are produced in minute quantities by minute organs, but have great control on almost all body functions. There are different hormones, each determining different functions like how tall a person will grow, how strong the bones will be, how well a person can react to stress and the reproductive ages. There is also a master gland called the pituitary which is situated somewhere deep in the brain, which controls all these organs. Small variations in the amount of these chemicals in the body produce significant effect on their respective control organ.

Thyroid is one such major gland, which produces a hormone called thyroxine or T4 as it is commonly called. This controls metabolism and emotional health to a large extent. Reduced amounts of T4 is very common in women, and with altered metabolism, there is increased musculoskeletal pain in various joints.

Here are some of the best ways to reduce Joint Pain from Hypothyroidism:

Step Up to Low-Impact Aerobics: Twenty to 60 minutes of near-daily aerobics   really any exercise that gets your heart pumping   can help speed up your metabolism and counter weight gain, a common hypothyroidism symptom and a contributor to joint pain. But if you have joint or knee pain, choose low-impact aerobics. Swimming is the ideal low-impact aerobic exercise   the water buoys your body and cushions joints.
Strengthen Your Muscles: Strength- or weight-training exercises build muscle mass, which uses more calories than fat even at rest. That promotes weight loss and can ease the strain on your joints. Stronger muscles also directly help protect nearby joints. For example, strengthening exercises such as squats, lunges, and leg lifts develop the muscles that support the knees. Start slow with 15 repetitions of each exercise. Then build up to three sets of 15 reps each.
Get Plenty of Sleep: Sleep is the time for muscles and joints to recover. If you're not sleeping well, you are not recovering as fast as you could be. What's more, when you're sleep deprived, you're likely to crave junk and comfort foods that can contribute to weight gain, which adds stress to your joints and increases joint pain. Aim for seven to eight hours of quality sleep each night.
Stick to a Healthy Diet: Replace the junk food that can lead to weight gain with choices that enhance your health. For example, add fatty fish to your diet. It's a good source of omega-3 fatty acids, known to decrease inflammation, which may be contributing to your muscle and joint pain. Coldwater fatty fish such as salmon, mackerel, and tuna have some the highest amounts of omega-3s. Also be sure to get lots of fresh fruit and vegetables high in antioxidants, which may counter inflammation, too.
Practice Yoga: Yoga poses are a great way to provide relief for joint pain while also increasing flexibility. For shoulder pain, look for poses that open your chest, like this simple pose: Sit with your feet flat on the floor. As you inhale, stretch your arms over your head. Clasp your hands together over your head and then turn your palms up toward the ceiling. Drop your shoulders and straighten up as if pushing through your head. Hold for 30 seconds. Release your hands, bringing them down behind you. Next, clasp your hands behind your back and lift your arms. Hold for another 30 seconds.
Don't Let Fatigue Win: Fatigue is one of the most common hypothyroidism symptoms. Even though you might feel listless, you'll benefit from exercise because it will rev your metabolism and help you maintain flexibility despite muscle and joint pain. If you're too exhausted to complete a full exercise routine, break it up into several short bouts   even 10 minutes done three times a day will be effective. Also, stretching and relaxation exercises within two hours of bedtime may help you sleep better.
Meditate for Stress Relief: Having a chronic condition such as hypothyroidism can be stressful, and that stress can actually contribute to pain and tension. That's why it's important to find ways to reduce stress, such as the practice of mindfulness meditation. This form of meditation teaches you how to distract yourself from what's bothering you by refocusing your attention, often on your own breathing. 
Thyroid hormones help all your organs work well. They control how your body uses food for energy.

What Do Thyroids Do

Thyroid hormones affect your metabolism rate, which means how fast or slow your brain, heart, muscles, liver, and other parts of your body work. If your body works too fast or too slowly, you won t feel well. For example, if you don t have enough thyroid hormone, you might feel tired and cold. Or, if you have too much thyroid hormone, you might feel nervous, jumpy, and warm.

What hormones does my thyroid gland produce?

The thyroid gland produces thyroxine (T4), which is a relatively inactive prohormone and lower amounts of the active hormone, triiodothyronine (T3). Collectively, T3 and T4 are referred to as the thyroid hormones. Twenty percent of the body s triiodothyronine is made by the thyroid gland; the other 80% comes from thyroxine converted by organs such as the liver or kidneys.

The thyroid gland also produces calcitonin from cells called C-cells. Calcitonin is understood to play a role in regulating calcium levels in the body, but its exact function in humans remains unclear. Thyroid hormone is one such chemical which has effect on all organs of the body including the joints. Vague pains may be due to thyroid disorders. They are easy to manage with treatment.

Joint Pain Due to Hypothyroidism - Know How You Can Manage it!

Thyroid disorders are associated with the thyroid gland. A thyroid gland is a butterfly-shaped gland situated right at the base of one s neck. The role of the thyroid gland is to carry out numerous metabolic processes within the body. The brain regulates the functioning of the thyroid gland through a feedback mechanism. There are a number of disorders, both severe and trivial, which could affect the thyroid gland.

Main symptoms of thyroid disorders:

Weight loss and weight gain

Changes in heart rate (arrhythmia)

Hair loss

Frequent mood swings

Swollen neck

Sudden bouts of moderate to high fever

Other symptoms include:

Numbness or a tingling sensation in the hands

Constipation

Abnormalities or irregularities in menstruation

Brittle nails and dry skin

Blurred vision

Weakened muscle tone and frequent tremors in the body

Treatment Options:

Intake of thyroid hormone pills may prove beneficial. Once you start with the treatment, you may notice significant improvement within the first two or three weeks. Generally, once affected by thyroid disorders, one might have to be on these medications his/her entire life. Over time, this treatment procedure should result in lowering of the cholesterol levels, increased energy; but in certain cases, might throw up side effects in the form of sudden and unexplained weight loss.



Anti-thyroid medications help reduce and regulate the secretion of the thyroid hormone, thus treating certain thyroid disorders (such as hyperthyroidism).

Beta blockers are drugs help in reducing high blood pressure, heart palpitations and controlling heart rate.

In severe cases, such as enlargement of the thyroid gland, surgery is advised by the doctor, in which the thyroid gland is removed. Tumors or thyroid nodules are also treated by this surgical process.

In cases of thyroid cancer, besides the surgical procedure, radioactive iodine therapy (radioiodine) is recommended. This therapy helps destroy the thyroid gland and other thyroid (malignant) cells which may be taking up iodine. However, the side effects of this technique are minimal. This procedure helps to destroy those tissues which may not have been removed by the surgery. If the thyroid cancer has spread to the lymph nodes or to other parts within the body, this particular mode of treatment can be very effective.

Types of Thyroid Disorders:

Hypothyroidism: This is a condition characterized by an underactive thyroid gland. In this case, sufficient thyroid hormone is not secreted in the body.

Hyperthyroidism: This is characterized by an overactive thyroid gland, that results in overproduction of the thyroid hormone.

Thyroid cancer: It is a type of cancer of the thyroid gland.

Goiter: This is a disorder wherein the thyroid gland gets abnormally enlarged.

Thyroid nodules: This is marked by swelling of the thyroid gland. If you wish to discuss about any specific problem, you can consult a endocrinologist and ask a free question.

Thyroid Disorders: Symptoms, Treatment and Types

 Thyroid is a small gland situated in front of the neck and secretes hormones like thyroxine (T4) and tri-iodothyronine (T3). These hormones control various functions of our body like heart, blood pressure, digestion, metabolism, growth, blood formation, brain function etc. Any fluctuation in the functioning of the thyroid gland can have a great impact on health. The thyroid gland is primarily responsible for energy and metabolism. This gland triggers the genes that make all the cells in the body conduct their specific jobs. But over a period of time, the optimum functioning of the thyroid may reduce because of specific reasons. The gland may start to under-produce or overproduce the thyroid hormone, which may lead to conditions known as hypothyroidism or hyperthyroidism, respectively. 

Patients with hypothyroidism may feel extreme tiredness and fatigue even though they may be sleeping more than before. An unexplained gain in weight, constipation, inability to stand cold temperatures, and constant pain in muscles and joints are some of the other symptoms of hypothyroidism. 
Hyperthyroidism, or overactive thyroid, is an endocrine disorder. Patients with this disorder may experience excessive sweating, fatigue, and intolerance to heat. They may even experience restlessness, puffy or protruded eyes, hair loss, and muscle weakness. Such patients may lose weight and are unable to sleep properly at night. In some cases, palpitations or abnormal heart rhythm may also be experienced. 
Complications of Thyroid Disorder 

Hypothyroid and hyperthyroid can cause a number of complications if patients don t take medications. It is important for you to not to ignore any of the aforementioned symptoms and speak to your doctor as soon as possible. 

Hypothyroid complications

Myxedema: This condition is characterized by slowed thinking, swelling of tissues, and accumulation of fluid around major organs like brain, lungs and/or heart. This condition may prove life-threatening if not treated on time. 
Enlarged goiter: This is characterized by enlargement of the thyroid gland because of a constant increase in the TSH levels. High cholesterol and triglycerides: This may eventually pave way for heart disease and stroke. 
Sleep apnea: Sleep apnea is a disorder that affects nighttime breathing where the brain that temporarily stops sending signals to the muscles that control breathing, or by an obstruction in the airway. This may prove fatal if left untreated. 
Low blood pressure: This means not enough blood is getting to capillaries and tissues, particularly in your hands, feet, and brain. You may have chronic nail fungal infections and cold hands and feet if so. 
Hyperthyroid complications 

Heart disorders (cardiac arrest): If left untreated, excess thyroid hormones can lead to congestive heart failure and heart rhythm disorders. 
Osteoporosis: Too much thyroid hormones interfere with the body s ability to use calcium to build bone. This may lead to brittle bones and osteoporosis. 
Thyrotoxic crisis: This is a rare yet life-threatening complication characterized by high fever, vomiting, irregular heartbeat, and agitation. 
Hypertension or high blood pressure: It is a condition in which a patient has high blood force striking the walls of the artery An early diagnosis can help make the treatment of this disorder easier. 
Depending on the condition of the thyroid condition, it requires different ways to manage it. The conventional TSH (thyroid-stimulating hormone) and T-4 (thyroxine) blood tests will be advised and the results should provide a reasonable confirmation of the condition. If doubts still persist an ultrasound or scan can also be ordered. In case you have a concern or query you can always consult an expert & get answers to your questions!

Is Your Thyroid Gland Working Against Your Body? 

Your thyroid is a small, butterfly-shaped gland situated at the base of the front of your neck, just below your adam's apple. Hormones produced by the thyroid gland do everything from maintaining your heart rate to regulating your body temperature to controlling your body weight. 
Millions of people worldwide suffer from thyroid dysfunction and several don't know about it. This is primarily because people don't tend to link the common symptoms first with a thyroid disease. Some people suffer from mood swings, trouble with memory, weight gain or fatigue, all of which they look upon individually as a problem and hence not piecing together the puzzle of their real medical condition. Here are a few insights that'll help you cope:
How does the thyroid gland work?
About 85% of the hormone produced by our thyroid gland is t4, which is an inactive form of the hormone. After t4 is made, a small amount of is converted into t3, which is the active form of thyroid hormone. T3 is then converted to free t3 or reverse t3. It is the free t3 that forms the base of thyroid functions. 
What is hypothyroidism?
Hypothyroidism, or an underactive thyroid, accounts for 90% of all thyroid imbalances. The signs and symptoms of hypothyroidism develop slowly, often over a number of years, which is why it is often missed from regular treatment charts. For instance, fatigue and weight gain are often attributed to stress, lifestyle changes and natural ageing process. But as time goes by, some of the symptoms show a higher level of manifestation like muscle weakness, elevated blood cholesterol, thinning hair, puffy face, hoarse voice and slowed heart rate. 
If left untreated, hypothyroidism may lead to goiter (enlarged thyroid), increased memory problems, low blood pressure, decreased breathing and in extreme cases, unresponsiveness and coma. 
This disease may also occur in newborns, infants and children. Symptoms include excessive sleepiness, poor muscle tone and constipation. It is important to diagnose and treat it early, as in severe cases it may lead to mental and / or physical retardation. In children and teens, it can result in stunted growth, and delayed puberty.
What is hyperthyroidism?
It's the opposite of hypothyroidism, which means in this case the thyroid overproduces hormones. Common symptoms include lack of sleep, weakness, irregular heartbeat, elevated blood pressure and hand tremors. While genetics are partially responsible for it, it is also triggered by autoimmune disorder. Hyperthyroidism can be treated with medication, radioactive iodine (not the first or best choice as it harms white cells too) and surgery. Keeping a focus on your calcium and sodium intake is crucial to curb the disorder.
Treatments: 
Conventional treatments rely mainly on drugs and surgery. Alternative treatments involve diet and lifestyle changes. Taking multivitamins, going gluten free, getting a good night sleep, and reducing stress is all said to help heal your thyroid gradually.

Thyroid Dysfunction and Treatment

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