Autoimmune disorders are one of the least understood disorders in the whole of medical science. Systemic Sclerosis is also an autoimmune disorder in which the skin undergoes changes in texture and characteristics. 

However, the changes are not confined to the skin alone. It can affect blood vessels, muscles, digestive system, heart, kidneys, as well as the lungs. It typically affects people in the age group of 30 to 50 years, but the good thing is that doctors can diagnose this at any age. 

It has been observed that more women fall prey to this disorder than men. The severity of symptoms may also vary from person to person. Nevertheless, the real cause of worry is the progressive nature of the disease. Due to this, it is, in fact, sometimes referred to as Progressive Systemic Sclerosis. 

Causes of Systemic Sclerosis 

It is an autoimmune disorder in which the immune system attacks the skin and precipitates the problem. The attack by Immune System precipitates increased collagen production in the body, which accumulates in the skin tissue. This leads to changes in characteristics and the appearance of the skin. 

Symptoms of Systemic Sclerosis 

Systemic Sclerosis affects only the skin in the early stages. It may lead to thickening of skin and development of shiny areas around bony areas, such as nose, mouth, fingers etc. However, as the disease progresses, it may limit movement of these affected areas. So one may have a problem in opening the mouth, parting fingers etc. 

Other symptoms are: 

  Loss of hair 

  Deposit of lumps under the skin 

  Blood vessels under the skin getting dilated 

  Pain in the joints 

  Breathing difficulties 

  Dry cough 

  Constipation 

  Diarrhea 

  Swallowing difficulty 

  Reflux of food from esophagus 

  Feeling of bloating after taking meals 

In addition to the above, one may also sometimes experience spasms in the blood vessels of fingers and toes. Legs and hands may turn blue or white if a person is undergoing emotional stress or is in extreme cold. This is also known as Raynaud s phenomenon. 

Risk Factors

Though the causes of the disease are not yet known, there are some risk factors which can make a person susceptible to this disease: 

  If a person is undergoing chemotherapy with certain drugs like Bleomycin or are exposed to stuff like silica dust, organic solvents etc., one may become susceptible to this disease. 

  Women are more prone to acquiring this disease than men. 

  If a person is a Native American or an African-American then too he/she is more susceptible to this problem. 

Treatment of Systemic Sclerosis 

Systemic Sclerosis can t be cured, but its symptoms can certainly be reduced to some extent. So, treatment is specific to symptoms one is experiencing, and may include using the following: 

  corticosteroids 

  immunosuppressants 

  nonsteroidal anti-inflammatory drugs 

  blood pressure medication 

  aid to resolve breathing difficulty 

  physical therapy, light therapy etc. 

The fact that this disease really can t be fully cured makes this a pretty scare disease. Silver lining is that medication and other treatment options are able to suppress most of the symptoms.

Systemic Sclerosis - What Causes It?

Bipolar disorder is one of the conditions which most people are aware of. However, not many can truly understand. Lets see some signs that inform a person of possible bipolar disorder in a child or a teenager:

While most kids go through a series of ups and downs on a regular basis, in the case of a child who has bipolar disorder, both the ups and downs can be characterised by relative extremes. Not only does the mood of the child change, but also there are other changes which take place. These changes affect the sleep cycle as well as the clarity of the affected child s intuition and the level of energy that is displayed. The set of people who are at the highest risk of developing bipolar disorder are those who have reached their late teen years and are entering adulthood.

There are ways to treat bipolar disorder, but the fact remains that it stays for life.
When a person has bipolar disorder, the manic phase may result in him or her acting happy or silly in an unusual manner, at least for a person who is around that age. In addition to this, a short temperedness may be displayed and there are problems in getting proper sleep. It is important to keep in mind the fact that in the manic phase, the person is quite likely to commit risky actions. As such, one must keep an eye on his/her affected child.

On the other hand, over the course of the depressive phase, the patient is likely to feel guilty and cut down on the amount of food that is eaten. There is a general loss of energy and even activities, which normally seemed engaging and fun may seem to have lost their allure during this phase. In some cases, thoughts of death and suicide may also be considered.

As a parent, it is important to be aware of the fact that bipolar disorder may not necessarily occur on its own. In fact, there are quite a few cases when it occurs with Attention Deficit Hyperactive Disorder (ADHD). It, in fact, has been seen that ADHD has spurred the success of a few sportsmen, like Michael Phelps. Having said that, it is important that we make efforts and ensure that such disorders do not affect the minds of people. Treatment is especially important as bipolar disorder can also lead to substance abuse and in extreme cases untimely death. 

Bipolar Disorder - Can It Be Detected?

In recent times, the advancement of medical science has substantially contributed in comprehending the Alzheimer s disease. Unfortunately, the number of individuals suffering from the disease is expected to rise in the next ten years which pose a threat to the allocation of health care resources and public health. Alzheimer s disease is thought to be a complex disease which influences a person s behavior as well as cognition through numerous mechanisms.

Can surgery be deemed as a treatment for Alzheimer s disease?
The surgery is a multicenter clinical trial which is making a new direction in clinical research. It is devised to halt or slow down the problems caused by the disease which gradually erases a lifetime of memories in elderly patients. Though there is no cure for Alzheimer s disease, it has been found that low-voltage electric charges delivered right at the brain. Only the symptomatic therapies for Alzheimer s disease are provided which do not have any effect on the evolution of the disease. The standard medical treatments for Alzheimer s disease include cholinesterase inhibitors along with a partial N-methyl D-aspartate antagonist. In most cases of mild to moderate symptoms of this disease, a combination of treatments is used according to the clinical history, age and condition of the patient.

Mental activity supporting cognition
Many patients having normal cognition or mild impairment have a fear that they may develop AD. Many experts are of the opinion that mentally challenging activities including brain teasers and crossword puzzles can be helpful in reducing the risks in such patients. Clinical trials are under the way for determining whether or not these types of activities have any substantial effect on halting the progression of AD.

Treating AD in its moderate to the severe stage
Numerous studies have shown that blockade of NMDA receptors by memantine can be used safely in combination with ChEls. This combination has been shown to delay the institutionalization in patients with Alzheimer s disease.

Treating secondary symptoms
A variety of behavioral as well as pharmacologic interventions can help in overcoming the clinical manifestations of the disease. These include anxiety, psychotic behavior, depression and agitation among others. The effectiveness of this disease can range from modest to excellent. No particular agent or dose of it can be unanimously accepted to be the sole treatment option for the wide range of clinical issues. Moreover, in the recent time, the FDA has not accepted any psychotropic agent for treating AD.

Along with these treatment options, there are behavioral interventions that can range from patient-centred approaches to caregiver training for helping manage the cognitive and behavioral manifestations of Alzheimer s disease. Last but not the least, it is very crucial to point out the significance of treatment in the early stages of AD in order to cure it better.

Alzheimer's Disease - Can Surgery Help You Treat It?

A bad habit could range from smoking or drinking to knuckle breaking or nail biting. A bad habit is one that causes or is likely to cause you or the others in your life, harm. Here are eight steps that can help you break your bad habit:

Try to understand your habit: The most important thing to break a bad habit is to know it first. In case that some habit is hurting you then you certainly need to let go of it. You initially need to set your mind about bringing an end to that habit. It is also important to understand how this habit of yours is hurting you or the ones around you.
Change your thinking: Even when we get to know we have some unfortunate habit, more often than not we are not prepared to separate it since we have practised that habit since a long time and it is by all accounts intense to break that one. We have to change our reasoning about the habit and take a look at it in negative viewpoints since a thing having negative perspectives will be simpler to quit.
Begin small: In case that you have a negative behaviour pattern since quite a while then go slow to break it down in light of the fact that a bad habit is hard to separate at once. Try not to attempt to do everything at once since you would not have the capacity to do as such.
Make tiny improvements: Try not to make extreme improvements to your habit since it is your habit and it will some way or another takes its time to break. Rather make little improvements with the goal that it will not aggravate you and soon you will encounter a noteworthy change in your behaviour and afterwards you will separate the habit totally on a more lasting basis.
Change your environment: A few habits are built because of the environment we live in. The steady surrounding makes us construct that habit in a manner that it gets stronger day by day. So in case that you understand that some negative behaviour patterns have overtaken your life and are not going down, attempt to change your surroundings.
Keep a check: Simply going ahead to bring an end to any habit will not give you appropriate results. Keeping a survey helps you in checking on how much of your bad habit you have defeated and how far you are from breaking it completely.
Reward yourself: Offer yourself a reward each time you see that you have stopped behaving in a certain way, or practising a certain habit. This goes a long way in motivating the individual to strive towards that end goal of breaking the habit completely.

Want to Break a Bad Habit - 7 Steps You Must Follow!

Parkinson s disease is a disorder involving the nervous system. It can start with a mere tremor of one hand and advances to slow movement and stiffness. The face might show little no symptoms in the beginning but the speech might become slurred. With every passing day, the condition worsens. This condition has no permanent cure but the symptoms can be improved with proper medication.

What are the symptoms?
Some unmistakable symptoms include the following:

A sudden shaking of the limb. A sudden tremor of the hand is a very common symptom of this disease.
A stiffness of the muscles that can limit the range of motion and sharp pain.
The posture of the body might get compromised. Often balancing problems are witnessed among many patients.
There could be problems with speech leading to soft, slurry or quick speech. The speech in some cases can become monotonous devoid of inflexions.
Parkinson s disease can lead to slow movement and makes performing of simple tasks difficult.
Patients often find writing very difficult
What are the possible causes of Parkinson s disease?

Specific genetic mutation can lead to Parkinson s disease in folks who have a family history of Parkinson s disease. Certain variations of the gene increase the risk of this disease
Exposure to certain environmental factors or certain toxins can trigger Parkinson s disease in an individual.
Certain cells in the brain known as Lewy bodies can trigger Parkinson s disease.
A certain kind of protein cells within the brain known as alpha-synuclein can trigger the Parkinson s disease in an individual
What are the risk factors?

Heredity: Having an immediate family member or a close relative suffering from Parkinson s disease can increase the risk of getting this disease in an individual
Age: Although not a prime risk factor, but an individual over the age of over 60 have an increased risk of getting this disease
Toxins: Exposure to pesticide or certain herbicide increase the risk of Parkinson s
Sex: Men are more likely to get Parkinson s disease than women
What is the medication for Parkinson s disease?

Carbidopa-levodopa: This is a natural chemical that gets passed to the brain and is converted to dopamine by the body. The benefits of this medication might reduce with increased symptoms.
Carbidopa-levodopa infusion: A popular drug in this category is known as the Duopa. It is administered directly into the small intestine in the form of gel through a feeding tube.
MAO-B inhibitors: Drugs from this group include rasagiline and selegiline. This is a powerful medicine. Many patient experiences hallucination during the initial days of consuming these drugs.
Anticholinergics: This medication is mainly used to counter tremors of the limbs in the early stage of the Parkinson s disease.

Parkinson's Disease - What Are The Risk Factors?

Do you believe that the world is a hostile place and you are a victim? Are you the one who often doubts his or her abilities? If so, you might be showing signs of low self-esteem. Interestingly, self-esteem has nothing do with your actual ability or talent. Your looks, weight or skills are not responsible for your low self esteem. It largely depends upon the fact that how you value yourself.

It has been observed in most cases that self-esteem is often affected by a number of reasons, including ill-health, unpleasant memories from the past, and termination of relationships. Low self-esteem is generally marked in survivors of physical or sexual abuse, victims of racial discrimination or people who have had a traumatic past life.

If you don t pay attention towards this issue, you might end up developing certain serious mental disorders. Low self-esteem is also the root cause behind the occurrence of mental disorders like borderline personality disorder, depression, etc. However, there is nothing to worry about it. There are certain simple things that are useful in building up your self-esteem.

Here s all that you need to do to start believing in yourself and be confident about your capabilities:

1. Remember your strong points: Make three separate lists of your strengths; achievements and your qualities that you admire. Take help from your friends, parents and other well-wishers for preparing these lists. These lists will help you in understanding your abilities and goodness. You will be able to believe in your strengths. You must read through these lists at least once daily.

2. Be positive: Optimism and a positive approach towards life are the key to success. Your self-esteem is influenced by the fact that how you look at life. Life is not a bed of roses. It is unavoidable that you will have to face critical situations or problems in life. But, what is important is to face them with courage and a faith in your own abilities. Be positive and stop developing negative thoughts about yourself. Get rid of thoughts like  I am a loser ;  I can t get rid of this problem ; etc.

3. Take care of your body: Your outward appearance sometimes works wonders in lifting up your inner-self and spirits. Keep yourself clean, trim your beard or hairs; cut your nails; don t forget to floss your teeth and maintain overall personal hygiene to develop a feeling of goodness.

4. Sleep well: A good night s sleep is essential for boosting up your self - esteem.

5. Eat right: A balanced diet is a key to good health. Eating the right food in the right way keeps your mental and physical health all right. Include minerals and vitamins in your regular meals. Avoid distractions like television or radio while taking meals.

6. Exercise: Regular workouts keep you away from mental-ill health.

7. Be cool and comfortable first: When it comes to your dressing, try to put on attires that you can carry well. Wear stuffs that you love the most.

How to Build your Self Esteem?

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