PCOS (Polycystic Ovary Syndrome) is a common disease of the endocrine system among women who have attained the reproductive age. Women with this condition generally have ovaries larger in size than the usual, containing small pockets of fluids, also termed follicles. These 'follicles' develop in each of the ovaries as diagnosed with the help of an ultrasound exam. Abnormal or extended menstrual cycles, unusual growth of hair and obesity are some of the common accompanying conditions associated with PCOS. This disorder can interfere with a woman's menstrual cycles, thus making pregnancy difficult. More so, this condition can also impact the way you look and if left untreated for long, can lead to underlying disorders such as diabetes and other cardio vascular diseases.

Causes of PCOS
1. Excessive Insulin secretion: Insulin is a hormone secreted by the pancreas, which allows the body cells to utilize the sugar; the most important energy store of your body. If you suffer from insulin resistance, your body's ability to utilize the insulin gets affected adversely. This forces the pancreas to secrete more insulin in order to keep up with the body's energy supply. This excess insulin might result in an increase in the production of androgen, which in turn, might interfere with the ovulation ability of the ovaries.
2. Low- level inflammation: Inflammation is the process by which your body's white blood cells fight infections. Studies reveal that women suffering from PCOS have a low level inflammation which acts as a catalyst in the production of androgens.
3. Can be hereditary: If you have someone in your family suffering from this syndrome, you might automatically be at a higher risk of developing this disorder.

Symptoms accompanying PCOS
1. Abnormal menstrual is the most commonly observed symptom. Women suffering from PCOS may have less than nine periods in an entire year and in some cases, even none. 
2. Excess secretion of male hormone, which is related to excess androgen production may result in symptoms, such as abnormal body and facial hair, acne and baldness, which is identical to that in men.
3. Unexplained increase in weight and difficulty losing it as well.
4. Another fairly noticeable symptom is depression.
5. Infertility

PCOS- Causes and Symptoms

Kidney is the most vital organ in the body as it eliminates the waste material from our blood. When kidneys fails to carry out its work effectively the waste materials gets accumulated in the blood and end up with many serious disease condition that affects the other vital structures in our body. The function of the kidney is carried out artificially by an external device called dialyser to purify the blood and remove the waste products from it. This procedure is called as dialysis. There are two types of dialysis they are haemodialysis and peritoneal dialysis. In Haemodialysis, the waste products are removed from the blood and there by the fluid and electrolyte balance is maintained.

Things a person should follow if they are undergoing haemodialysis

Love your heart: Patients undergoing dialysis are at more risk of getting cardiac problems. So it is best advised to follow few of the following measures to take care of their heart
Keep your blood pressure and cholesterol levels under control
Quit smoking
Reduce stress
Have healthy low fat and heart friendly diet
Get regular physical activity but avoid excessive strainers activity that may require extra effort from your heart
Maintain a healthy weight
Diet: Dialysis not only removes the waste matters from your blood but sometimes also the essential electrolytes and nutrients. Protein, potassium sodium and phosphorus are the major things that are to be noted.
Encourage the patient to take high quality protein rich foods like meat, fish, milk, egg and chicken which is essential to improve your muscle strength and immunity.
Have a check of your sodium level and take sodium rich foods accordingly, as excess sodium may increase the fluid intake.
Limit your fluid intake: Use ice cubes instead of water or use small cups of water. Make sure you measure every sip of water you take.
Don't Overeat: Slow down while eating and stop eating when you feel full. don t over load your stomach

Haemodialysis - 4 Things a Person Must Follow if Your Undergoing it

Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks. A person s mood and emotions can be altered drastically due to bipolar disorder, but they do not have more than one personality. Split personalities problem is more commonly seen in those with personality/dissociative disorders. 

There are four basic types of bipolar disorder; all of them involve clear changes in mood, energy, and activity levels. These moods range from periods of extremely  up,  elated, and energized behavior (known as manic episodes) to very sad,  down,  or hopeless periods (known as depressive episodes). Less severe manic periods are known as hypomanic episodes.

Bipolar I Disorder  defined by manic episodes that last at least 7 days, or by manic symptoms that are so severe that the person needs immediate hospital care. Usually, depressive episodes occur as well, typically lasting at least 2 weeks. Episodes of depression with mixed features (having depression and manic symptoms at the same time) are also possible.
Bipolar II Disorder  defined by a pattern of depressive episodes and hypomanic episodes, but not the full-blown manic episodes described above.
Cyclothymic Disorder (also called cyclothymia)  defined by numerous periods of hypomanic symptoms as well numerous periods of depressive symptoms lasting for at least 2 years (1 year in children and adolescents). However, the symptoms do not meet the diagnostic requirements for a hypomanic episode and a depressive episode.
Other Specified and Unspecified Bipolar and Related Disorders  defined by bipolar disorder symptoms that do not match the three categories listed above.
The disorder has two strong phases: 1) Bipolar Mania and 2) Depression.

Mania-

Mania is a state of heightened energy and euphoria - an elevation of mood. It is in direct contrast to depression. Mania can vary in severity from hypomania, where, in addition to mood and energy elevation, the person shows mild impairment of judgement and insight, to severe mania with delusions and a level of manic excitement that can be so exhausting that hospitalisation is required to control the episode.

The mood, energy and other related symptoms define both mania and hypomania, with psychotic features being an 'add on' component experienced by a sub-set of individuals. 

You have an intense sense of well-being, energy and optimism. It can be so strong that it affects your thinking and judgement. You may believe strange things about yourself, make bad decisions, and behave in embarrassing, harmful and - occasionally - dangerous ways.
 
Like depression, it can make it difficult or impossible to deal with day-to-day life. Mania can badly affect both your relationships and your work. When it isn't so extreme, it is called 'hypomania'.
 
If you become manic, you may notice that you are:

Emotional:

very happy and excited
irritated with other people who don't share your optimistic outlook
feeling more important than usual. 
Thinking:

full of new and exciting ideas
moving quickly from one idea to another
hearing voices that other people can't hear.
Physical:

full of energy
unable or unwilling to sleep
more interested in sex.  
Behaviour:

making plans that are grandiose and unrealistic
very active, moving around very quickly
behaving unusually
talking very quickly - other people may find it hard to understand what you are talking about
making odd decisions on the spur of the moment, sometimes with disastrous consequences
recklessly spending your money
over-familiar or recklessly critical with other people
less inhibited in general.
If you are in the middle of a manic episode for the first time, you may not realise that there is anything wrong   although your friends, family or colleagues will. You may even feel annoyed if someone tries to point this out to you. You increasingly lose touch with day-to-day issues   and with other people's feelings. 

Depression- 

The feeling of depression is something we all experience from time to time. It can even help us to recognise and deal with problems in our lives. In clinical depression or bipolar disorder, the feeling of depression is much worse. It goes on for longer and makes it difficult or impossible to deal with the normal things of life. If you become depressed, you will notice some of these changes:

Emotional:

feelings of unhappiness that don't go away
feeling that you want to burst into tears for no reason
losing interest in things
being unable to enjoy things
feeling restless and agitated
losing self-confidence
feeling useless, inadequate and hopeless
feeling more irritable than usual
thinking of suicide.  
Thinking:

can t think positively or hopefully
finding it hard to make even simple decisions
difficulty in concentrating. 
Physical:

losing appetite and weight
difficulty in getting to sleep
waking earlier than usual
feeling utterly tired
constipation
going off sex. 
Behaviour:

difficulty in starting or completing things   even everyday chores
crying a lot   or feeling like you want to cry, but not being able to
avoiding contact with other people.
Causes:

Biological Causes: Experts say that patients with bipolar disorder often show physical changes in their brains. Nobody is sure why the changes lead to the disorder.
Genetic Traits: Researchers are involved in finding out whether or not the causes of bipolar disorder arise out of genes and other hereditary factors. If you have a first-degree relative or a sibling who is/was affected by this condition, you would probably have it too.
Neurotransmitters: Mood swing disorder is caused by an imbalance in brain chemicals known as  neurotransmitters .
Treatment Methods:

Initial Treatment: The initial treatment method is to take medications to balance and control the mood swings. After the symptoms are in control, one has to start working with his/her trusted doctor for chalking out an effective and practical long-term treatment procedure.

Recovery from substance abuse: Problems related to excessive alcohol and drug abuse are solved by this therapy. Failing this step, this disorder can be unmanageable.

Day care treatment: Day care treatment programs can be recommended by your doctor. This treatment method includes counseling and support which keep the bipolar traits under control.

Hospitalization: Hospitalization or immediate medical support is recommended in case of suicidal thoughts or when a person starts exhibiting erratic behavior (being psychotic).

Medications: Medications include the administration of antipsychotics (such as ziprasidone, olanzapine), antidepressants (usually in combination with a mood stabilizer or an anti-psychotic), mood stabilizers (such as valproic acid, lithium, divalproex sodium) and anti-anxiety medications.

Bipolar Affective Disorder - Symptoms and Treatments

Chronic kidney disease or CKD is the decreased function of the function of the kidney for a minimum of three months or more. In this the end stage renal disease usually refers to the end of the kidney function where the kidneys work for less than 15% of what they are supposed to. The kidneys play a vital role in the human body and if they do not function properly then a person can die. The functioning of many organs depends on the kidneys. However, the main function of the kidneys is to remove the products and regulate blood and water, control blood pressure, promote healthy and strong bones, and produce hormones.

Here are 5 facts about kidney disease you should know about:

1. Causes of the kidney disease: There are two main common causes of the end-stage kidney disease. These are preventable causes. These are diabetes and high blood pressure, but then kidney disease can be caused by other inherited diseases such as infection, trauma or polycystic kidney disease.

2. Serious Stages: The kidney disease has five stages and stage 5 is known as the end stage renal disease; this is the point where patients usually need dialysis or kidney transplant to lead a sane life. The stages of kidney disease are:

Stage 1   Slight kidney disease
Stage 2   Mild decrease in kidney function
Stage 3   Moderate decrease in kidney function
Stage 4   Severe decrease in kidney function
Stage 5   End stage renal disease

3. Detection of the disease: Kidney disease is usually difficult to detect because of the presence of very few symptoms. Age, gender along with the blood test is one way to determine information regarding kidney function. The people who are at a risk of getting kidney disease are:

    Over the age of 55 years
    People who suffer from hypertension and diabetes
    Ethnic groups such as Asians, Africans, Americans, Pacific Islanders and Hispanics

4. Signs and Symptoms: CKD is usually considered to be a silent disease and many people don t know that they are suffering from the disease. The signs and symptoms of the disease are:

    Fatigue and weakness
    Nausea, vomiting and loss of appetite
    Dizziness
    Numbness and headaches in hand and feet
    Frequent urination

5. Renal Replacement Treatment: This is the treatment for the end stage of the kidney disease. Dialysis involves the replacement of some part of the lost function of the kidneys and is usually continued throughout life. There are 2 types of dialysis:

    Hemodialysis: This cleans the blood via an artificial kidney which is hooked to the machine
    Peritoneal Dialysis: This removes the excess water and waste products and cleans the blood of the body by using the peritoneal cavity as a filter. 

5 Facts About Kidney Disease You Should Know

Diabetes refers to the condition when there is an excess of glucose in your body. Though glucose is beneficial for the proper functioning of the body, an excess can lead to serious consequences. Over the years, diabetes has over the years emerged as one of the fatal diseases, one that once developed has no known cure. This condition is preceded by various perceptible symptoms, some of them are-

1. Insatiable thirst

The onset of diabetes is almost always accompanied by a nagging thirst, one that refuses to be quenched despite drinking plenty of water.

2. Frequent tendencies of urination

A frequent tendency of urination is one of the primary precursors of diabetes.

3. Acute hunger

Having bouts of acute hunger is one of the most predominant premonitions of diabetes.

4. Exhaustion and fatigue

In case you are suffering from diabetes, you will inevitably feel tired and exhausted all the time.

5. Blurring of vision

Diabetes is one of those rare conditions that threaten to affect and damage the eyesight. The blurring of vision comes hand in hand with the onset of diabetes.

6. Sores which take a long time to heal

One of the most fatal symptoms of diabetes is when the sore that you have suffered from takes a longer time than necessary to heal.

Some of the complications which diabetes invite are-

1. Cardiovascular problems

Diabetes considerably increases the risk of a host of cardiovascular problems and ailments like heart attacks, chest pain, and stroke.

2. Damage to the kidneys

The pair of kidneys that human beings are endowed with has the responsibility to remove the toxins from the body. An excess of diabetes in the body unsettles the purging ability of the kidneys.

3. Damage to the eyes

The onset of diabetes, among other things, puts your eyes at great risks. The condition tends to damage the blood vessels of the retina and can even cause blindness in some.

4. Skin disorder

Diabetes puts your skin at great risks. You may suffer from various bacterial and fungal infections among other ailments, due to an excess of glucose in your body.

Symptoms and Complications of Diabetes

While we all know substance abuse is a social issue and learning that a loved one is affected by the problem can be nearly heart-breaking. It is definitely not something that can be easily accepted. At the same time, the affected individual needs all your love and attention and more importantly support to get through the situation. It is important to not show anger or frustration at the person but to empathize and help them get out of the situation. 

Read on to know some of the ways in which you can play an active role in supporting your loved one under such circumstances. This involves both of you coping with the situation at hand, as well as helping the person come out of the abuse. 

Educate yourself: When you are trying to help a person, you should know in detail about the substance that was being used and its ill effects. This gives you greater credibility, unlike the person who got carried with the happy feeling it gave and got into abuse. 
Ensure safety: This is both for the affected individual and yourself. With the required substance not being available, the person could look at harming either self or others, especially ones who are trying to get them out of the abuse. Though the intent is to help, they are looked at as people who are depriving the feel-good feeling produced by the substance, which is no longer easily available. Therefore, ensure safety. 
Talk openly: In the beginning, be a good listener. Once you get their confidence, make them understand that the entire situation is making you upset and perhaps angry or frustrated too. Get them to focus on your proposal of getting out of the habit together. If they are willing then this can ensure greater success in quitting the habit. Get to understand how exactly the habit developed including the people responsible for it, the circumstances leading to it, and the various chemicals that were used. The duration and frequency are also important. Tell them it is okay and that you will both get out of it with each other s support. 
Participate in therapy sessions: Individual counseling will work effectively for the primary client, but it is also important for family members to get involved. The counselor also would need support beyond the few counseling hours for completely getting rid of an individual s habit. Therapy can help you learn how to manage the issues back at home. 
Find your  me-time : With all that is going on, you will need some time for yourself to just be. Eat well, stick to your workouts, sleep well, keep your friends, and make time for your hobbies. These will ensure you are in good shape to support the affected individual. It is not possible for you to help another person when you are not in great shape yourself.

Substance Abuse - How Should You Cope With Someone Going Through It?

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