SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

The heart is a muscular organ that pumps blood to the entire body through a network of arteries and veins. This network contains big vessels which branch out further to supply blood to the distant organs. There is, therefore, some pressure that the heart and thereby the vessels need to exert to push the blood through these vessels. This is known as blood pressure, and normal pressure levels range from 90-140(systolic)/60-90(diastolic) mm of Hg. However, due to various reasons, this pressure could be more, which is one of the first signs of heart disease. 

Causes of increased blood pressure: 

Thickening of the blood vessels. With age, the elastic blood vessels naturally turn rigid and less elastic, so there is more pressure required to push blood. It is natural for people over 55 years of age to have higher readings of blood pressure. This is known as primary hypertension (HTN) 
Narrowed blood vessels. This happens due to cholesterol accumulation along the walls of the blood vessels. Faulty dietary habits along with sedentary lifestyle have increased the incidence of hypertension due to this condition, known as atherosclerosis. Critical atherosclerotic narrowing of renal arteries lead to renovascular HTN that is one of the commonest of secondary HTN. 
Other Causes of secondary hypertension are: 

Kidney problems 
Thyroid hormone disorders 
Congenital heart defects 
Chronic alcohol abuse 
Adrenal gland tumours 
Chronic use of medications like birth control pills, pain killers, etc. 
Unidentified and uncontrolled hypertension can be silent and can lead to more severe conditions like heart attack and stroke. India is fast becoming the new hypertension capital of the world. Some of the common risk factors are: 

Age 
Family history 
Being obese or overweight 
Sedentary lifestyle 
Smoking 
Alcohol consumption 
Excessive salt intake 
Stress levels 
Ethnic background 
Symptoms: 

Hypertension can go undetected for years together, but if there are risk factors like diabetes and high cholesterol, it is advisable to periodically monitor blood pressure. 
Headaches, nosebleeds, and shortness of breath should not be ignored. These can be the first warning signs of hypertension, and if detected early, preventive measures can be taken. 
If there are co-morbid risk factors, it is advisable to constantly keep a check on BP readings. 
Management: 

This includes a combination of diet and lifestyle modifications. 

Quit smoking and alcohol: Of the many wonders quitting smoking can do, reducing BP readings is just one. The improvement would be almost instantaneous. Quit or else reduce alcohol and see dramatic improvements. 
Weight management: Through a combination of diet and exercise, ensure that weight is brought under control. Set a target BMI (Below 26 kg/m2) and work towards it religiously. 
Diet: Reduce salt, increase potassium, increase vitamin D, eat a heart-healthy diet, and see the hypertension readings improve. Please find attached and reviewed copy for health tip for posting

High Blood Pressure - All You Need To Know About It!

A heart attack does not always have obvious symptoms, such as pain in your chest, shortness of breath and cold sweats. In fact, a heart attack can actually happen without a person knowing it. This condition is known as a  silent heart attack , medically known as  silent ischemia , occurring due to the shortage of oxygen supply to the heart muscle. The causes of a silent heart attack are similar to that of a heart attack. 

They include- 

Conditions like: 
Obesity or excess weight 
Diabetes 
High Blood pressure 
High cholesterol 
Heart Diseases 
Lack of exercise 
Age, usually above 65 
Consumption of tobacco or smoking 
High consumption of alcohol 
A silent cardiac arrest makes one more vulnerable to another heart attack that could be fatal. Diagnosis: The only method to diagnose if you had a silent heart attack is through imaging tests, such as echocardiogram, electrocardiogram, Holter Monitoring or others. These tests can show certain changes which might be indicative of a heart attack. An analysis of one s overall health and the symptoms can aid in deciding whether few more tests are required. 

How would you prevent a silent heart attack? 
1.   Get your cholesterol and blood pressure count tested regularly. 
2.   Refrain from smoking. 
3.   Get your VO2 max checked regularly. 
4.   Live a healthy lifestyle: Refrain from smoking and excessive alcohol consumption; exercise daily, eat healthy. 
5.   Control high blood pressure, cholesterol, and diabetes 
6.   Be aware of your body and call on a doctor if you feel there s anything which is bothering you. 

If you wish to discuss about any specific problem, you can consult a doctor and ask a free question.

Know Everything About Silent Heart Attacks

Be it burgers, bagels, muffins, sandwiches or simple toasts, bread has made headway into the diets of a huge portion of the populace. Although a staple diet for many since time immemorial, the consumption of bread has increased extensively in the recent past. But, which type of bread should we intake to incur the best health impacts is a question that bothers many. The general assumption is that the wholegrain variety is the best alternative. However, the barrage of marketing tactics makes it impossible to distinguish the best variety from the others. 

There are a whole lot of myths surrounding the best variety of bread and you must choose wisely before settling for one particular type. It is expedient to look beyond the overt appearance or the name of the bread, one needs to be wary of the ingredient before taking a call.

Mostly, white bread is made out of refined flour which is often striped off essential nutrients and fibers. To worsen the situation, white bread is often bleached with certain chemicals to enhance its appearance.
Certain assumptions deem brown bread as the healthier option. Unfortunately, it isn't true always. More often than not, brown bread is simply white bread with artificial coloring added to it or is caramelized. They essentially add no surplus nutritional value.

Similarly, multigrain bread can often mislead the consumers about its health impacts. Unlike whole wheat bread, multigrain breads are usually chemically treated with softened grains. This does not effectively recover the lost nutrients of the bread.

Whole wheat bread has more pronounced health benefits. It contains more wheat germ and fibers in comparison to the more processed varieties of bread. Having evaded the toxic additives, it has relatively healthier effects on our blood sugar levels.

As you realize that the bread that you eat does not necessarily affect your health favorably, wisdom lies in seeking out the least harmful variety. In that context, rye bread or spelt bread contains greater amount of minerals. Besides, bread made from barley, oats and millets have greater mineral content than the commercially hybridized varieties and promote better health.

Brown Bread Vs White Bread Vs Whole Grain?

The term 'chest pain  is a very common term and is usually used in day to day life. Basically, chest pain refers to the pain that may generate in your chest, shoulder and can travel to your ribs, jaws and towards your arms. The feeling of the pain can be sharp or dull, depending on the severity of your condition and cause.

There can be several reasons behind chest pain. You need to conduct a few tests to examine the real cause of the chest pain. It is always advised by health experts to take the symptoms of chest pain very seriously in order to avoid any serious problem in the future. Most of the severe and life-threatening diseases behind chest pain involve lung and heart problems. People having serious heart problems often feel discomfort, followed by pain in their chest area.

Symptoms
Chest pain which is related to any heart disease such as heart attack usually has symptoms like:

Feeling of fullness and tightness in the chest region
Vomiting
Nausea
Burning or crushing pain, which travels from the chest to jaw, hands and back region.
Weakness
Breathing problem
Usually, it is very tough to distinguish whether the pain is associated with a heart problem or not. But generally chest pains which are not related to heart problems involves symptoms like

Sensation in your mouth
Problem in swallowing food
Pain that worsens when you cough
Burning sensation in your chest
Common causes of chest pain

Angina: Angina is a medical condition described as a feeling of discomfort or pain in the chest region. This situation occurs when your heart muscles don't receive blood, which contains rich oxygen. Angina is a symptom of Coronary Heart Disease (CHD). The pain can take place in your shoulder, jaw, neck and arms also.
Lung problems: People with lung disorders can encounter various types of chest pains. But some common causes are:
Pleurisy: It is a type of medical condition, which occurs due to inflammation of the lining of chest and lungs. Due to this, you feel a sharp pain at the time of breathing, coughing or sneezing.
Pneumonia: It is a type of lung infection, which causes chest pain.
Pneumothorax: It is a type of lung disorder, which occurs when a portion of your chest gets collapsed.
Asthma: It is a type of condition, which occurs due to shortness of breath and causes chest pain while coughing, sneezing and breathing.
Gastrointestinal problem: Gastroesophageal reflux disease (GERD) is also a common reason for chest pain such as burning sensation in your heart.
Other causes of chest pain: There are several other reasons of chest pain such as muscle strain, ribs injury, shingles, anxiety and panic attacks. It is always important to visit a physician whenever you encounter any of such chest pain symptoms.

How Chest Pain Related to Heart Problems?

Breathing is life, without breathig, there is no life. Who knows this better than an asthmatic or someone with breathing problems like wheezing, coughing and shortness of breath 24/7? If you have breathing problems, read on about possible causes and treatments for them

Causes

There can be a number of causes of breathing problems. They can happen due to colds, acute sinusitis or inflammation of sinuses. This usually subsides in a week or two with the inflammation going down and the sinuses draining out.
But if you are still experiencing breathing problems, you could be in more dangerous territory.
Breathing difficulties can happen in a case of asthma, allergies, and infections of the lungs, bronchitis and even heart problems especially if you feel a shortness of breath during exertion. These can all be long-term problems that need proper management.
Symptoms
Chronic issues that cause breathing problems, especially asthma and allergies have a number of symptoms like

Nasal and chest congestion
Runny nose
Itchy or watery eyes
Cough
Wheezing
Laboured and/or shallow breathing.
A number of virus and allergens like pollen reach the lungs via the nasal passage. Any inflammation in the nasal passage due to an allergy is a major cause for concern because the number one trigger for asthma is allergies. If left undiagnosed and untreated, these can make life hell for you.

Chronic obstructive pulmonary disease or COPD, which includes emphysema and chronic bronchitis, also causes breathing problems. Breathing issues can also stem from other serious diseases like lung cancer, tuberculosis, and pneumonia. Most of these can be diagnosed by a specialist.


How are breathing problems treated?



Breathing problems caused due to asthma and allergies are usually treated by avoiding allergy triggers like air pollutants, pollen, dog hair, dust, mites or dander.
Wearing masks, avoiding peak traffic, staying indoors during low air quality days, all make a significant difference to allergy and asthma sufferers.
Medications are another way to treat breathing problems due to asthma and allergies. Allergy drugs such as antihistamines and decongestants can make it easy to breathe for some.
Inhaled steroids are also given to people with chronic allergies and sinusitis for reducing inflammation in the airways. Allergy shots to reduce sensitivity to allergens are another option.
Asthma is treated with inhaled or oral drugs that help open nasal airways and reduce inflammation. These cut down on breathing difficulties because the airways are cleared of excess mucus and inflammation.
If you have more serious issues like cancers, heart disease and lung diseases, the medication will vary according to your diagnosis. Your specialist will diagnose the problem first and set you on a proper course of medication.
The last piece of advice before we go, don t ignore breathing difficulties especially if they persist beyond 2-3 weeks, get yourself a doctor s appointment.

Breathing Problem - Common Causes Behind It!

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