SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

The CAD (Coronary Artery Disease) is a condition where the blood flow in your arteries is impaired. This happens when the blood vessels that supply blood to your heart are damaged. As a result, plaque builds up in the arteries and the blood flow to the heart is decreased.

This will eventually lead to chest pain or angina and other symptoms. If the arteries are blocked completely, you may suffer a heart attack later on. It is one of the leading causes of death and heart attacks all over the world.

What are the causes of CAD?

The CAD may be caused due to an injury to the inner part of the coronary artery. This may be due to the following factors  

High blood pressure and cholesterol

Smoking

An unhealthy or sedentary lifestyle

Diabetes

If the inner wall of the artery is damaged, deposits made of cholesterol and other cellular wastes are collected in the region. The process is called atherosclerosis. If this plaque surface breaks, the platelets in your blood will try to fix the artery. In the process, these platelets are accumulated in the area. Too much accumulation can block the artery.

As the arteries are responsible for providing oxygen-rich blood to your heart, blockage in the region will lead to a heart attack.

Moreover, Coronary Artery Disease may be caused if you have a family history of heart diseases. It is more likely to occur when you are over 65 years of age. Factors such as obesity and high levels of stress can also lead to this condition. 

Symptoms

The common symptom of Coronary Artery Disease is angina or pain in the chest. However, the condition may be accompanied by other symptoms, like  

Tightness, heaviness, burning or a squeezing sensation in the chest

Sweating

Dizziness

Shortness of breath followed by extreme fatigue

Pain in the arms, shoulders or the back

Severe pressure in the shoulders and arms that lead to heart attack

The angina symptoms are commonly misunderstood as symptoms of indigestion. Be aware and seek medical assistance immediately.

Treating CAD with Ayurveda 

The following Ayurvedic herbs are helpful for preventing the deposits of harmful fats in your blood vessels  

Guggulu

Chandraprabha Vati

Combination of herbs like Amlaki, Arjuna, Punarnava, Kutki and Triphala

Another important treatment procedure for the disease, as prescribed by Ayurveda, is meditation. Meditating for about 20 minutes every day will help you relax and calm your nerves. It will help you enhance your mental health and happiness. This will keep your heart healthy.

This prevents the body from forming angiotensin is a hormone that causes your blood vessels to get smaller which increases your blood pressure. This baeltablet helps in Lower angiotensin levels, then help widen your blood vessels and let your blood flow more easily this reduces your blood pressure. This Bell tablet helps in blocking the effects of angiotensin on your heart which helps in lowering your blood pressure and these roots helps in preventing blood clots from forming, some do this from making substances called clotting factors and others keep the clotting factors from working or preventing other chemicals from forming so that clots cannot develop. What is most important is that all these herbs help in dissolving existing plaque. This drug also works as thromboxane it prevents platelet to stick together to form a clot.

You can also opt for Panchkarma therapy that is a rejuvenating experience consisting of massages and steam baths. High cholesterol is effectively treated using this therapy. 

To prevent risks of CAD, you must exercise regularly and avoid consuming foods high in fats and sugar. Reduce the amount of preserved foods. Eat more fresh fruits and vegetable daily. Furthermore, get plenty of sleep and stop consuming alcohol or cigarettes to stay healthy.

CAD (Blockage In Arteries) - How Can Ayurveda Handle It?

Arrhythmia is a disorder which is characterized by improper and irregular heartbeats; be it too slow or too fast. This problem occurs when the electrical impulses that are used to regulate your heartbeat don t work in the correct manner. Your heart may beat irregularly, too slow or too fast.

Symptoms
Although this disorder does not yield many symptoms, a few noticeable symptoms of arrhythmia are slow heartbeat, or a racing heartbeat, chest pain, breathing difficulties and dizziness. Arrhythmia can lead to inefficient pumping by the heart, leading to bouts of fainting. A severe symptom of this disorder is ventricular fibrillation, wherein the ventricles tend to quiver instead of transporting blood. This symptom can cut off blood supply to the vital organs, which may lead to death.

Causes

Coronary artery disease: In this disease, arteries of the heart can get blocked, leading to irregular heart beat and impaired heart functioning.
A heart attack: An ongoing heart attack usually leads to irregular heartbeats.
High blood pressure: High blood pressure problems make you more vulnerable to this condition.
Impaired functioning of the thyroid glands: An overactive or underactive thyroid gland can lead to heart arrhythmia.
Excessive smoking and alcohol consumption: These habits can cause problems with the blood vessels in the body, thus increasing risks of this particular condition as well as other cardio-vascular diseases.
Stress: Too much stress can lead to high blood pressure; that is again linked to heart arrhythmia.
Treatment
Mild symptoms of arrhythmia do not require treatment. However, complications resulting from it warrant treatment. The various treatment options for this condition are:

Pacemaker: A pacemaker is a device that is used to regulate your heart rhythms. It is placed in the body by a surgical procedure and an insulated wire is put, connecting the heart to the pacemaker. In case of an irregular heartbeat, the pacemaker sends out impulses to correct the improper heartbeat.
Implantable cardioverter-defibrillator: This device is used to prevent a dangerous symptom of heart arrhythmia, a symptom wherein the ventricle quivers. It is similar to a pacemaker as it is also placed near the collarbone. In case it detects an abnormal rhythm, it sends out shocks to reset the heart rhythm.
Maze procedure: This is a surgical procedure wherein incisions are made on the upper heart tissue to create a scar tissue. Scar tissues act as insulators to prevent stray impulses.
Alternative therapies: Alternative procedures such as yoga and meditation can help remedy the disorder.

Is Your Heart Missing a Beat Regularly - Could it be Arrhythmia?

Peripheral Artery Disease (PAD) is a disease of blood vessels that are located outside the heart and brain. The condition develops due to fatty deposits in the arteries and veins that stops the blood flow to the heart and mind as the case may be. It narrows the artery and restricts the blood flow, which causes problems to other organs of the body such as kidney, liver, and stomach.


Symptoms of Peripheral Artery Disease-
Peripheral Artery Disease is the most common type of condition in people. Some people may not even notice the symptoms. The symptoms include:

Pain in the hips and lower leg area.
Brittle toenails.
Short breath while taking stairs.
Pain in the calf.
Numbness and coldness in the leg around a calf
Hair loss on legs and feet
Erectile dysfunction in men
Repeated sores and ulcers in legs
Causes of Peripheral Artery Disease-
The most common cause of Peripheral Artery Disease is the deposit of fatty substances inside the arteries. The fatty deposits build in the arteries gradually with a process called Atherosclerosis. Most of the time people do not know that they are facing the problem of Atherosclerosis. With time deposits increase and the arteries become narrow. It restricts the blood flow and causes problems for other organs.
Another cause for Peripheral Artery Disease is clot created in the arteries due to diabetes. Also, this problem is common in diabetic patients and increases with old age.

The risk factors that contribute to the development of Peripheral Artery Disease are high blood pressure, bad cholesterol, obesity, and diabetes.

Diagnosis of Peripheral Artery Disease-
The primary way to test and diagnose Peripheral Artery Disease is to check the blood pressure in the arm and ankles. If the pressure is low as compared to arm in the ankles, one might be facing Peripheral Artery Disease. It is commonly known as the ankle-brachial index. Other ways to determine Peripheral Artery Disease are CT scans, angiography, and blood tests. Since the disease is prevalent and gradually progress, most of the time it remains undetected.

It is essential that Peripheral Artery Disease gets detected and treated well in time. If the condition persists for a more extended period of time, it may result in loss of leg, increased chances of coronary artery disease and carotid atherosclerosis.

Treatment for Peripheral Artery Disease-
The only way to treat Peripheral Artery Disease is to indulge in physical activity. A regular regime of exercise and physical work will help a person to burn fat and makes the arteries fat free. Doctors suggest that daily 30 minutes of walking or gyming will help treat Peripheral Artery Disease with significant effects. One may notice the signs in just a couple of months.

Along with exercise, one also needs to monitor the weight and eating habits. Foods that are rich in fats and bad cholesterol should be avoided. Make changes in the lifestyle and eat a healthy balanced diet. Include fruits and fresh vegetables in the diet and follow a low carb diet for regular food intake. If a person is addicted to smoking and alcohol, then he/she should consider leaving the bad habits for their own good health.

Take Away-
Above are some of the common and tried treatments. However, it is advisable to consult a doctor before opting for any of these options as these treatments are depended upon the condition of the patients.


Learning In depth About Peripheral Artery Disease!

Angioplasty is the procedure of opening a coronary artery blockage with the help of wire balloon and stent. This procedure is done to open the blocked coronary arteries if they are causing symptoms or acute heart attacks.

HOW IT IS DONE?

The procedure is usually done in local anaesthesia. A wrist artery (radial) or a groin artery (femoral) is used to gain access to the coronary artery as is done in angiography. A hollow tube called a catheter is passed upto heart artery and through this, a guidewire is passed across the blockage and over this wire balloon is passed and blockage dilated.

After this balloon is removed and the metallic stent is passed over this wire. The stent is then inflated and it takes its shape of the hollow tube so that the flow in the coronary artery is restored.

WHAT ARE INDICATIONS OF ANGIOPLASTY AND STENTING:

An acute Heart attack is the most definite indication of angioplasty and stenting. At the time of the heart attack, there is an urgent need to restore the blood flow of block coronary artery which is usually not possible with medicines alone. Angioplasty is the most effective and definite way of opening the artery urgently in such situation.

SHOULD ALL BLOCKAGES BE OPENED UP BY ANGIOPLASTY AND STENTING?

NO, all blockages do not warrant this procedure. There is some amount of risk involved in the angioplasty procedure itself. When the risk of blockage is considered more than the risk of opening the artery then the procedure is indicated. Patients who are doing good on medicines may be followed up without angioplasty.

All About Angioplasty!

Over the last few decades, the word cholesterol has assumed a different connotation. It has come to be known as a silent killer that spells doom for health. However, what we need to realize is that a certain amount of cholesterol is essential for the proper functioning of the body. The liver produces about 85% of the cholesterol that is required by the body normally. The ever changing food habits have introduced a lot of processed foods that are loaded with saturated fats. Along with this, reduced physical activity has led to accumulation of cholesterol in the blood.

The types of cholesterol are based on the density and we have 2 types of density that is Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). LDL is more dangerous than HDL, called as bad and good cholesterol respectively. In addition, the triglycerides and lipoprotein are also critical indicators of overall cholesterol levels. Depending on a person's age, height and weight, normal levels are derived for each of these four.

Because of their density of the cholesterol molecules, as they are circulating in the blood stream, they tend to get sluggish and settle down along the walls of the blood vessels, referred to as plaque. This plaque attracts more and more cholesterol from the blood and the layer gets gradually thicker. This reduces the thickness of the blood vessels and in severe cases even completely blocks blood flow to important organs like the brain and heart, leading to severe conditions like stroke and heart attack respectively.

However, it is not always that all cholesterol is bad. It is one of the essential things for the proper body functions with the main functions listed below.

1. Each cell in the body requires it to form the cell membrane, the protective layer around the cells
2. Synthesis of vitamin D is done with the help of cholesterol, which is very essential for skin health
3. It also helps in hormone formation. In addition to steroids, other hormones like testosterone, estrogen, cortisol require cholesterol as a main ingredient
4. Formation of neurotransmitters and overall nerve function requires cholesterol. This ensures optimal neurological functioning.

So, as noted above, there are, both good and bad aspects to cholesterol. It is not all that dangerous a thing that it is made out to be. The trick is to maintain a good level of cholesterol so that the body's requirements are met, and at the same time, the harmful effects are kept at bay. Some important parameters to manage, include the percentage of bad cholesterol in the blood and the ratio of triglycerides to HDL in the blood. These are considered fair indicators of heart health and if need be, lifestyle changes and/or medications can be undertaken to manage overall health and reduce risk of heart disease and stroke.

Cholesterol: Good and Bad of It

Don't wait any longer, manage your Cardiac Surgeon online with a Lybrate doctor today

Consult for Cardiac Surgeon - Online and Easy!

FilterClear All

COMMON SPECIALITIES

COMMON ISSUES