SGLT2 (sodium-glucose-co-transporter 2) inhibitor is an oral tablet used in conjunction with exercise and diet to improve blood glucose control in Type 2 diabetes mellitus patients.

The medication works by targeting and helping prevent sodium-glucose transport proteins from allowing glucose that has been filtered by the kidneys to be reabsorbed into your bloodstream.

Who is SGLT2 Inhibitor suitable for?

This drug is not suitable for everyone. Selection of the right patients is crucial to understand the mechanism of the medication and see improvement in the condition.

SGLT2 Inhibitor is given to patients with Type 2 diabetes mellitus as a second-line drug in case the first line of treatment, metformin, fails to keep high blood sugar levels in check.

If the patient has hyperglycemia i.e. high, uncontrolled blood sugar, and a Body Mass Index (BMI) equal to or greater than 30 due to the accumulation of fat in the abdominal region (central obesity), then SGLT2 Inhibitor could be a useful medication. The drug not only works to reduce high blood glucose but also helps with weight loss. However, in patients with normal BMI, the medication does not induce weight loss.

SGLT2 Inhibitor may not be suitable for patients with a history of urinary tract infection. Hence, it is advisable for all patients to undergo a urine test before starting with the dosage. If the test results are normal, then only you can discuss the dosage with your doctor/healthcare provider and start taking the prescribed medications immediately.

Benefits of Taking SGLT2 Inhibitor :

The benefits of using SGLT2 Inhibitor are as follows  

Helps reduce excess weight if the patient is obese. If taken in the correct dosage as prescribed, you can lose up to 5 Kgs in about three months.

Helps reduce Systolic blood pressure   if a diabetic is living with hypertension, SGLT2 Inhibitor can bring down systolic blood pressure.

As an anti-diabetic drug, SGLT2 Inhibitor works to control high blood glucose and improves glycemic control. Thus, with the help of the drug, Type 2 diabetes mellitus patients can keep their HbA1c levels at 7% or less.

Side Effects

One major side effect of SGLT2 Inhibitor is urinary tract infection. SGLT2 Inhibitor drug filters excess blood sugar from the body in the form of urine. Frequent urination or filtering of wastes through the urethra may lead to infections. Therefore, it is imperative that patients are informed about the mechanism of the drug and its probable side effects before taking the medication. One way to avoid urinary tract infections is to maintain good hygiene   wash and clean your private areas after urination.

SGLT2 Inhibitor can also cause dehydration in the patient, as a lot of fluid is drained out of the body. Patients are advised to have a glass or two of water more than what they usually drink.

SGLT2 Inhibitor is an effective oral medication for Type 2 Diabetes mellitus. Speak with your doctor and get yourself thoroughly checked before you start taking the drug.

SGLT2 Inhibitor - Know Merits & Demerits Of It!

Food plays a vital role in lowering the cholesterol apart from timely medication. Here is a list of 10 foods that contribute to a great extent in lowering the cholesterol level:

Oats: Changing the morning meal is the first action you should take. Oatmeal can bring down the LDL level to a staggering 5.3 percent in a matter of 6 weeks. It contains beta-glucan, which is capable of absorbing the LDL present in the blood.
Red wine: You can cheer to reduced cholesterol with a glass of red wine in hand. A study conducted by the Universidad Complutense de Madrid in Spain found that red wine can reduce the cholesterol level up to 9 percent owing to a vital component known as Rioja present in it.
Salmon Fish: Fatty and salmon fish contains Omega-3 fatty acids. They are known to be extremely effective for diseases such as dementia, cardiovascular diseases and much more. A study conducted by the Loma Linda University found that Omega-3 can increase the HDL by up to 4 percent. 
Nuts: Nuts can reduce the cholesterol by up to 9.3 percent, a study by the American Journal of Clinical Nutrition revealed. 1.5 oz of regular consumption of nuts greatly helps in bringing down cholesterol. Since nuts are very rich in protein, portion control is necessary to refrain putting on weight.
Beans: A research conducted by the Arizona State Polytechnic University revealed that adding beans to soup can bring down the LDL up to 8 percent. Owing to their rich fibre content, they effectively absorb cholesterol. Some of the beans that can be tried include kidney, black and pinto beans.
Cocoa: A study conducted by the AJCN reported that the daily intake of cocoa increases the HDL by over 20 percent in 3 months. Due to its high antioxidant content, it streamlines the blood flow and doesn t let platelets stick together.
Garlic: 2-3 cloves of garlic per day can dramatically reduce cholesterol-limiting LDL into the artery. It can prevent other conditions such as blood pressure, infections and blood clotting. Garlic can be consumed with any regular dish. 
Olive oil: Olive oil has multiple health benefits. It contains a compound known as MUFAs that lowers cholesterol and helps to get rid of abdomen fats. You can use it with salads, roast vegetables and marinate chicken.
Avocado: Avocado contains monounsaturated fat that helps to raise the level of HDL and lower the LDL in the body. It contains Beta-sitosterol that absorbs cholesterol and brings down the count of it in the body. Owing to its high-calorie content, portion size should be looked into.
Margarine: Two margarine can lower the LDL level up to 14 %. They are capable of absorbing cholesterol from the bile. It can be consumed with toast in the morning or as a snack in the evening.

Cholesterol - 10 Foods That Lower it!

Causes and Symptoms of Renal Hypertension

High blood pressure is characterized by an increased force that the blood exerts on the blood vessels when it moves through the body. Renal hypertension is a blood pressure disorder where the arteries that carry blood to the kidneys become narrow, as a result of which the blood pressure through these vessels increases.

Causes

It is caused when the arteries that supply blood to the kidney get narrow or get blocked. This can cause the kidney to release specific hormones that signal the body to retain water and sodium. This can put additional pressure on the blood vessels which leads to increased blood pressure. It can also be caused by atherosclerosis which is characterized by hardening of the arteries. Improper development of the arteries can also lead to renal hypertension.

Symptoms

The symptoms of renal hypertension are:

Feeling confused
Blurred vision
Regular headaches
Bleeding from the nose
Gradual decline in kidney function
Possible long-term damage to the kidney
Feeling lethargic and drowsy
Loss of appetite
Dryness in skin
Muscle cramps
Breathing difficulties

Treatments

The diagnostic procedure for this disorder consists of blood, urine, doppler ultrasound and CT angiography or MR angiography tests. Treatments for this disorder usually include medications to ease blood pressure. Preventive measures include modifications in lifestyle such as following a proper diet, limiting smoking, restricting sodium or salt in the diet and following an exercise regimen. Steps should also be taken to reduce stress. Yoga and meditation are highly beneficial to control the condition. Sometimes intervention is needed in the form of PTRA and stenting.

High Blood Pressure and Kidney Disease - Causes and Symptoms!

What is Palpitation?
Palpitation is a feeling of awareness of your own heart beat. It is usually described as heart rate being either too fast (racing), too slow or a sensation of missing a beat.

Types of palpitations?
Normal (Benign)
- These palpitations occur as a response to physical or mental stress like exercise, fever, pain, fear, anxiety etc. 
- They are harmless and settle on their own once the precipitating factors disappear. They do not require any medical treatment.

Abnormal
- These palpitations occur due to some underlying abnormality in either the structure of heart or the beating of heart. 
- These can be dangerous and at times life threatening. They may or may not settle on their own and require some medical treatment.

Warning signs that suggest palpitations are abnormal?
Palpitations are abnormal, if they are associated with chest heaviness, chest pain, uneasiness, sweating, weakness, giddiness, feeling of black out, fainting, nausea, vomiting, seizures. Palpitations are more likely to be abnormal in people who have some existing heart disease and these patients should report to their doctor at the earliest.

What to do during palpitations?
1. Stay calm. 
2. Call for help. If u are alone avoid driving, use a taxi or auto, go to your nearest hospital/doctor and try to get an ECG during the palpitations. If you are helping someone having palpitations, if they faint, call for help, start CPR if they remain unresponsive and take them to the nearest hospital. 

Which doctor can treat palpitations?
Doctors who specialise in the treatment of palpitations are called Electrophysiologists. They specialise in heart rhythm and are capable of performing a variety of complex tests to identify and treat different types of palpitations.

Which investigations are used to diagnose palpitations?
ECG: Taken during palpitations and when the patient is normal is a very helpful tool. 
Holter: Externally applied recorder, which continuously records heart rhythm for 24 hrs. 
ELR: Extended loop recorder, is like holter, but it records rhythm for longer durations. 
ILR:  Internal loop recorder is attached within the body for recording rhythm for long duration. 
EPS: Electrophysiology study, is the most sure shot test to diagnose, identify and treat 
Palpitations.

What is EPS?
EPS stands for Electrophysiology study. By this test a trained Electrophysiologist studies the conduction and formation system of heart beat, to understand the source, cause and type of palpitation. It is a simple and safe procedure of 2 to 3 hours and can be done as a day care procedure (by admitting the patient for a few hours in hospital, with discharge on same day).

It requires fasting for 4 hrs, some standard blood investigations and is done with local anaesthesia and if required it can be combined with treatment like ablation in the same sitting.In the procedure Electrophysiologist take catheters into your heart to study and stimulate the palpitations and understand them. Once found they can use various techniques to stop the palpitations, the techniques are called Ablation.

What are the treatment options available for palpitations?
There are many options depending upon the nature of palpitations and condition of the patient: 
- Drug therapy 
- Cardioversion where either a drug or electric shock is given to stop palpitations immediately. 

Ablations using many sophisticated computer softwares 
Device Therapy like ICD (Internal cardiac defibrillator) 
Combination of all the above therapies.

Your Electrophysiologist and you as a team can make a choice about the options that will be best for you.

Palpitations - Everything You Need to Know

For long, there have been campaigns and discussions about the harmful effects and diseases associated with alcohol consumption. In most cases, it is not the alcohol, but the quantity consumed that affects a person. Limited consumption of alcohol can, in fact, work to your advantage. Alcohol, when consumed in moderation, helps to avert, check or improve many medical conditions and health ailments.

Deal with common cold effectively: According to research, the antioxidants present in wine helps to fight common cold better. Limited intake of alcohol, red wine to be precise (~1-2 glasses per day), can, thus, help to reduce the instances of common cold significantly.
Weight loss made easy: Studies conducted by the Oregon State University suggest that certain varieties red wine (the Red Muscadine Wine) can play a pivotal role in weight reduction. The Red Muscadine, a variety of wine grapes used to make red wine contains ellagic acid. It is this ellagic acid that helps to cease or slow down the growth and development of the fat cells. Red wine also helps to manage fatty liver effectively.
Keep cardiovascular diseases at bay: The high-density lipoprotein (HDL), also known as the Good Cholesterol is indeed good for the body. It acts as a shield, keeping the heart hale and hearty. Moderate alcohol consumption helps to elevate the level of HDL. One of the main reasons attributing to heart attacks are the small blood clots that block the arteries of the brain, heart, and neck. Alcohol (limited intake) has been able to put a check in the formation of such blood clots.
Reduced instances of cognitive impairment: Reports suggest that people who consume alcohol within limits are less likely to develop dementia and Alzheimer's disease. Moderate consumption tends to make the brain cells fit and more active, thus, enabling the cells to deal with stress and other related factors.
A little wine for a better libido: Limited consumption of wine is good for a better sexual life. Research indicate that the antioxidants present in wine act as a catalyst, resulting in an improved libido (lowers the incidences of erectile dysfunction in men). A little wine can work wonders for women as well (increasing their sexual desires and feelings).
Enjoy a diabetes-free life: Type 2 Diabetes and the associated ailments and complications can make life miserable. However, people who consume a small quantity of alcohol (preferably 1-2 glasses per day) are at a lower risk of developing diabetes (Type 2). A path-breaking finding indeed!
People with moderate alcohol consumption are also at a lower risk of developing gallstones. The high silicone content in beer helps to strengthen the bones, but only when consumed within limits. Beer is also rich in calcium, magnesium, and vitamins (thiamine, riboflavin).

Alcohol In Controlled Quantity - Can It Be Good For You?

Are you looking for effective and natural ways to prevent heart blockage and blood pressure management? You should consider taking Ayurvedic measures, which have been proven to be quite effective in dealing with various issues of the heart. Usually, heart blockages are difficult to deal with and a surgery has to be carried out for recovery. With Ayurvedic remedies, you can solve such issues without the concern of harmful side effects on your body.

Ayurvedic management of heart blockage
For effective prevention and management of heart blockages, you need to create a certain Ayurvedic medicine using basic ingredients.

Mix lemon, ginger, apple vinegar and garlic together and boil on a light flame.
After the quantity gets reduced, leave the mixture to cool.
After this, add some honey in the solution, and store it in a bottle for use. You have to take this medicine every morning after waking up.
Note all the ingredients are chosen for their unique and beneficial features.
Lemon contains more than 19 qualities, and garlic and ginger are good for dealing with gastric issues. Apple cider vinegar is given great importance in Ayurveda, and honey is good for your blood. Hence, this medicine is ideal for treating heart blockages effectively.
Ayurvedic management of blood pressure
High blood pressure or Rakta Gata Vata refers to an elevation in the pressure of blood in your arteries. The increase in pressure is based upon your age, activities, diet, and medical history.

The Ayurvedic remedies for the prevention and control of blood pressure include the following:

Avoid consuming eggs, meat, tea, coffee, pickles and table salt.
Abstain from smoking.
Increase your intake of food items such as lemon, garlic, parsley, grapefruit, cottage cheese, Indian gooseberry, and watermelon.
Engage in regular exercise as it is important for lowering and preventing your chances of high blood pressure.
Laugh a lot and keep away from anxiety and stress factors.
Make a juice of garlic cloves, wheat grass and basil leaves. Have this regularly for reduced chances of high blood pressure.
Mix onion juice with honey and have the mixture every day.
Make a paste using garlic and buttermilk, and drink it regularly.
Grind roasted watermelon seeds, add water to the powder, strain the liquid, and have it twice every day.
It is important for you to visit an Ayurvedic practitioner before starting to take Ayurvedic measures for heart blockage or high blood pressure on your own. This will ensure that you are prescribed the best measures by a qualified and experienced doctor.

Heart Blockage & Blood Pressure - How Ayurveda Can Help You Prevent It?

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