Brain metastases from systemic cancer are the most common type of intracranial neoplasm in adults, being almost 10 times more common than primary malignant brain tumors, which cause a significant burden on the management of patients with advanced cancer (1). The lungs represent one of the most frequent sources of metastases to the brain, with a probability of (36 64%) (3). Symptoms suffered by the patients include headaches, epilepsy, focal weakness, numbness or changes in mental status. The prognosis of patients with brain metastases is not optimistic and the median survival time is  1 2 months if left untreated. The 1-year survival rate has been recorded as 10.4% (4,5). The treatment of metastatic brain tumors is complex; not only due to being able to provide local control and improve neurological function, but also due to factors such as age, performance and systemic disease status and the size, volume, location and number of metastases at presentation

CyberKnife is a robotic radiosurgery system with a linear particle accelerator (linac), which is coupled with real-time imaging to track and compensate for the patient s or target s motion. As a relatively non-invasive treatment modality, CyberKnife demonstrates certain benefits, including a more accurate target localization and improved dose delivery for the management of metastatic brain tumors that allows higher biologically effective dose delivery without increased incidence of toxicity.

In the present case, the results for the treatment of multiple brain metastases after CyberKnife surgery with a 7 8 Gy marginal dose was promising. CyberKnife for metastatic brain tumors is an effective and safe method for reducing the marginal dose prescribed for multiple brain metastases and for minimizing the radiation-related neurotoxicities. In conclusion, CyberKnife, a focused, highly-targeted radiosurgery and fractionated radiotherapy is particularly useful for multiple brain metastases. CyberKnife provides the advantage of the management of local recurrence and a tolerable complication rate. Although the treatment of brain metastases has been performed with CyberKnife, the clinical significance and optimal dose fractionation scheme require further investigation.

In case you have a concern or query you can always consult an expert & get answers to your questions!

CyberKnife Therapy Of 24 Multiple Brain Metastases From Lung Cancer!

What menstrual problems are to women, prostate problems are to men. The prostate is a gland in the lower abdomen that aids in the production of semen. The prostate is walnut sized in a young man, but can get enlarged with age. As it grows bigger, it can cause a number of problems. These are commonly seen after a man celebrates his 50th birthday.

There are three common prostate problems faced by men. Some of the symptoms that can tell if a man has a prostate problem are:

1. Difficulty faced while urinating
2. The urge to urinate frequently at night
3. Constant feeling of a full bladder
4. Pain while urinating
5. Blood in the urine

Prostatitis

This can be defined as inflammation of the prostate gland. In most cases the cause of this inflammation is unknown. However, there are two types of prostatitis; bacterial and nonbacterial. While the former reacts well to antibiotics, the latter is more difficult to control. Symptoms of this disease vary from one person to the next. Some of the factors that could trigger this disease are:

1. Chemical irritants
2. Past bacterial infection
3. Dysfunctional pelvic floor muscles
4. Sexual abuse
5. Chronic anxiety

Enlarged prostate

As mentioned earlier, as men get older, the prostate gland tends to grow in size. This growth is benign, but can block the bladder neck and prostatic urethra. This can cause problems urinating and lead to acute urinary retention. This can be very painful. Inserting a catheter can provide temporary relief and help release stored urine. Chronic retention is much less common and is associated with high bladder pressure and can damage the kidneys.

Prostate cancer

Advancing age and family genetic history are said to be the main triggers of prostate cancer. This type of cancer can remain restricted to the prostate gland in its early stages but may spread to the other glands as the cancer advances. This can also cause the growth of secondary tumors in the bones.

The only way to correctly diagnose a prostate problem is with a thorough physical examination. This includes a digital rectal exam where the doctor will insert a gloved finger into your rectum to check the size of your prostate, a blood test, mid stream urine tests and ultrasounds. In some cases a biopsy of the prostate may also be required. Depending on the diagnosis, your doctor may prescribe antibiotics, surgery, radiotherapy or hormone therapy to manage your prostate.

Are You at Risk of a Prostate Disease?

As men enter their middle age, many of them develop issues with their prostate gland. There are certain symptoms that would tell you that your prostate glands have stopped functioning smoothly. It is recommended that you opt for a thorough check up when you suspect something wrong. This is because untreated prostate issues can lead to prostate cancer later in life. To avoid such a situation, it is best to get it treated as soon as possible.

Here are certain common symptoms which would make you aware of the issues that might affect your prostate gland.

Bladder Discomfort: When you frequently start experiencing the feeling of your bladder not emptying completely, then it is time to consult an urologist for the problem. Such bladder discomforts are linked to prostate gland malfunctioning.
Increased frequency of urination: Ideally a person urinates around six to eight times a day. Depending on the intake of liquid or water it can even rise up to ten times. But if you are urinating more than ten to twelve times, then it is definitely a matter of concern and you should approach medical help for it.
Dribbling of urine: when you notice that the flow of urine is not stable and it starts dribbling for a long time, then you must understand that the prostate gland is not functioning properly. This is one of the earliest signs of prostate disorders.
Waking up frequently at night to use the washroom: It is not very normal to wake up frequently at night to use the washroom. But when you notice an increase in your trips to the washroom at night, it can be a sign of prostate malfunctioning.
Pain in penis or blood in the flow of urine: If you feel pain when you are trying to empty your bladder or anytime during the day, then it is a matter of concern. Similarly, if there is a flow of blood, even in the slightest, in your urine, then it is time to opt for a check up with your medical practitioner.
Hence, these are the major symptoms which reflect that the functioning of your prostate gland is not as smooth as it is supposed to be. If you can relate with any of these symptoms, ideally you must immediately consult your medical practitioner and take an expert opinion. Medical science has progressed a lot in contemporary times and prostate disorders are very much treated by medicines and procedures. It is a very much curable problem provided you get the right help at the right time.

Prostate Enlargement - 5 Signs You Are Suffering From it!

Are you aware of the link between air pollution and cancer? Air pollution refers to the mixture of several harmful substances, which lead to various serious health hazards on exposure. The primary sources of air pollution are man-made, including fumes from automobiles and the smoke from burning fuels. Desert dust, radon gas, and several other natural sources of air pollution are equally dangerous. Air pollution is classified into outdoor and indoor air pollution. It is highly associated with increased risks of developing cancer. Smoking is considered to be one of the major agents, which pollute the air and increase the chances of cancer to a large extent.

Outdoor air pollution

Outdoor air pollution is strongly linked with cancer development.
As every person is exposed to some form of air pollution, it has a more harmful effect on the whole population across the globe as a general threat.
A certain part of outdoor air pollution referred to as PM 2.5, or solid dust particles, are highly responsible for the development of cancer.
The chances of cancer increase with the increase in PM 2.5 levels in the air.
Indoor air pollution

There are several sources of indoor air pollution that are closely associated with an increased risk of cancer.
The sources include fuels used for heating homes and for cooking, radon, and tobacco smoke.
Second hand smoke is another harmful indoor air pollutant that causes cancer.
Second hand smoke

Secondhand smoke increases the risk of cancer development, along with the risk of developing other diseases such as stroke and lung disease.
A lot of people all over the world get exposed to second hand smoke.
A lot of deaths occur due to cancer because of second hand smoke exposure which is common every year, all over the globe.
Radon

Radon is a natural radioactive gas, which is associated with increased risks of developing lung cancer.
It is found at low levels outdoors. It may also build in high concentrations indoors.
Although radon exposure does not pose a huge threat for cancer, a lot of radon-associated cancers develop due to exposure to radon, along with tobacco smoke.
Benzene

This is a flammable liquid having no color and with a sweet odor.
It is closely associated with the development of leukemia and cancers affecting other cells of the body.
Cigarette smoking and tobacco smoke are major cancer causing elements that are found in the air commonly. Both of these are quite harmful. It is recommended that you not only quit smoking, but also keep away from passive smoking.

Pollution and Cancer - How They Are Related?

Lung cancer is the cancer killer of both men and women in the world. When you think of risk factors for lung cancer, what comes to mind? Most of us think about the risk associated with smoking cigarettes, but did you know that air pollution can also cause lung cancer? Overwhelming evidence shows that particle pollution in the outdoor air we breathe like that coming from vehicle exhaust, coal-fired power plants and other industrial sources - can cause lung cancer. Particle pollution increases the risk of dying early, heart disease and asthma attacks, and it can also interfere with the growth and function of the lungs. 

What is Particle Pollution?

Particle pollution is a mix of tiny solid and liquid particles in the air and can be made up of a number of components, such as acids, organic chemicals, metals, soil and dust particles. It can be emitted directly from wood stoves, forest fires, vehicles and other sources, and it can also form from other types of pollution that come from sources like power plants. 

Why does particle pollution harm our bodies?

While breathing in larger sizes of particle pollution can be harmful to our health, smaller particles are more dangerous. Bigger particles can irritate your eyes, nose and throat, but our natural defenses help us to cough or sneeze them out of our bodies. Unfortunately, those defenses don't keep out smaller particles, which get trapped deep in the lungs and can even get into the bloodstream, causing damage to our health.



Who is most at risk?

As for who is at risk for health problems from breathing in particle pollution. Those who live where particle pollution levels are high is at risk. Some people face higher risk, including children, the elderly, people with lung and heart disease and diabetes, people with low incomes, and people who work or exercise outdoors.

How do we protect ourselves from particle pollution?

Check the air quality index forecast for the day and limit your activity if pollution levels are high. Avoid exercising along heavily traveled highways regardless of the overall forecast.

As individuals, we can play our part in reducing air pollution levels by trying to avoid creating more of it. Choosing  active travel  options where possible, like walking and cycling, can help reduce pollution levels from transport and is also a great way to be more active, which is linked to a reduced risk of cancer and other diseases. In case you have a concern or query you can always consult an expert & get answers to your questions!

The Connection Between Lung Cancer & Outdoor Air Pollution!

Lumpectomy is a surgery where a cancerous or benign tumour is removed from a breast along with some surrounding tissues. The amount of tissue removed varies according to the nature of the tumour. It is a form of breast-conserving surgery. It is also called a partial mastectomy.

Lumpectomy is the first option of treatment for women diagnosed with early-stage breast cancer.

What is the goal of lumpectomy?

Lumpectomy aims to remove the cancerous cells from the breast and at the same time maintaining the appearance of the breast. Studies have proved that for early stage breast cancer, lumpectomy is as effective as mastectomy (complete removal of the breast).

Doctors may recommend lumpectomy to remove precancerous cells as well.

Pre lumpectomy measures-

If you are under any other medication or if you suffer from allergies, inform your doctor. Other pre-surgery measures include-

  Stop taking aspirins or any pain relieving medication

  Your doctor will recommend you to not drink or eat anything 8-12 hours prior to the surgery.

The procedure:

A mammogram and a biopsy reveal the exact location of a tumour. Lumpectomy is performed under general anaesthesia. The surgeon makes a small incision over a tumour to extract the cancerous cells and the surrounding tissues. Sometimes doctors have to perform sentinel lymph node surgery or axillary node dissection.

The surgeon then closes the incisions with sutures. The sutures may dissolve over time or may have to be extracted later by a doctor.

If you have undergone lumpectomy and sentinel node biopsy, you will be discharged on the same day as the surgery as soon as your blood pressure stabilizes.

However, after lumpectomy with axillary node extraction, you may have to stay in the hospital for 2-3 days.

Therapy after lumpectomy

Your oncologist will recommend a follow-up radiation therapy to destroy the mutated cells that may have remained in the area where a tumour had developed. Radiation reduces the risk of breast cancer recurrence.

You might also have to undergo hormone therapy. Some types of breast cancer need female hormones like estrogen and progesterone to grow. Hormone therapy inhibits the development of cancerous cells by not allowing these hormones to reach the cells.

Your doctor will advise you to avoid strenuous physical activities for at least a month after the surgery.

Lumpectomy is a safe surgical procedure that can root out tumours or precancerous cells from the breast without deforming the shape of it.

Breast Lumpectomy - All You Should Know!

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