Hypopituitarism is defined as a condition in which the pituitary gland is unable to produce enough hormones. Under-secretion of pituitary hormones affects reproduction, body growth and blood pressure. It also results in pre-mature aging.

The pituitary gland is a small bean-shaped gland situated at the base of your brain, behind your nose and between your ears. Despite its size, this gland secretes hormones that influence nearly every part of your body.

In hypopituitarism, you have a short supply of one or more of these pituitary hormones. This deficiency can affect any number of your body's routine functions, such as growth, blood pressure and reproduction.

Few Causes:

Head injury

Tuberculosis

Radiation treatment

Stroke

Brain tumors

Brain surgery

Meningitis (brain infection)

Hypophysitis (autoimmune inflammatory disorder)

Sarcoidosis is an infiltrative (accumulation of cells and tissues in excess of the normal amount) disease which occurs in various organs.

Impaired hormone secretion by the pituitary gland is caused by genetic mutations.

Sheehan s syndrome: It is a condition in which the pituitary gland gets damaged due to severe blood loss during childbirth.

Hypothalamus (a part of the brain which is located above the pituitary gland) diseases wherein the pituitary activities are directly affected by the hypothalamus.

Symptoms:

Fatigue

Reduced sex drive

Decreased appetite

Anemia

Irregular menstruation, pubic hair loss, hot flashes (feverish heat), and inability to breast-feed properly because of low breast milk production).

Dwarfism in children

Weight loss

Increased sensitivity to cold temperature

Infertility

Facial puffiness

Reduction in body hair or facial hair

Treatment Options:

Hormone replacement drugs include:

Corticosteroids: Adrenocorticotropic hormone deficiency leads to low production of adrenal hormones (different kinds of hormones such as cortisol and adrenalin, produced in the endocrine glands). These drugs act as a replacement of adrenal hormones.

Growth hormone: Growth hormone, also known as somatropin, is injected beneath the skin. This treatment method promotes growth, which balances the height in children. Growth hormone deficiency in adults is also cured by these medications to some extent.

Surgery: Surgical procedure is needed if the condition of hypopituitarism is the result of a tumor. The doctor will remove the tumor through surgery, thus resulting in normal growth.

Radiation: Radiation therapy helps in reducing the size of the tumor which causes stunted growth or pre-mature aging.

Hypopituitarism: Causes, Symptoms and Treatment

Absolutely indispensable to your existence is the proper functioning of your brain. Not only does your brain ensure a normal functioning of your body, but also it controls all your vital organs. Yet, brain disorders are among the most common diseases the modern populace has to confront. Tumorous growth in the brain affects the health of the brain in the most significant of manners. Be it benign or malignant, anomalous growth of the brain tissues leads to brain tumor. Some of the most evident causes of brain tumor are genetic dysfunctions, exposure to harmful radiations and immune-suppressants. You may detect the incidence of brain tumors through some of the more obvious symptoms like acute headaches, seizures, projectile vomiting as well as some fairly subtle conditions like a feeling of numbness, coordination problems, etc. The immediate recourse to brain surgeries and expensive treatments often do not yield the desired results. As a consequence, many seek an alternative therapy which can potentially soothe the trauma and fight the disease.

Replete with the benefits of ancient medicinal knowledge, Ayurveda offers remedies, which heal the diseases without causing any side-effects. The natural, herbal therapies improve your immunity from within; enhance your bodily strength and your will to live. It also aborts abnormal cell growth and helps in normal regeneration. Some of the most reliable Ayurvedic remedies have been enumerated below.

1. Aswagandha: Aswagandha herb has fascinating healing properties. They play a major role in restoring strength and immunity in your body. It is endowed with anti-inflammatory properties and is beneficial anti-oxidant. It supplements the essential nutrients, which improve the functions of the brain and minimize the adverse effects caused by harmful radiation.
2. Curcumin: Curcumin has been known to disintegrate malignant cells from your body. It not only is a great anti-oxidant, but also improves immunity. It has gained popularity as a cure for brain tumors as well.
3. Guggul: Guggul is known to revitalize the damaged cells and impart good health. It enhances oxidation potentials of the body and speeds up recovery from brain tumors.

Treatment of Brain Tumor With Ayurvedic Remedies 

There is no trustworthy evidence regarding what causes brain tumors, but there are a few risk factors that have been substantiated through research. Children and young people who receive radiation around the head are susceptible to developing tumors in the brain once they grow up. Also, people with a certain kind of rare genetic condition like neurofibromatosis may develop a brain tumor though such cases are very few in number. Age is also an important factor as people aged over 65 years are diagnosed with brain tumors at quadruple times higher than children and younger people.

Types of Brain Tumours-

A primary brain tumor originates in the brain, and they may or may not be cancerous. Some tumors can be benign, which do not spread in the surrounding tissues and are not very malicious. However, that does not signify that they will not cause any harm over time. Sometimes these tumors can be severe and cause a threat to the life of the sufferer. The National Cancer Institute reports that approximately there were 23, 380 fresh cases of brain tumors in 2014.

Identifying the Symptoms of Brain Tumors...

The symptoms of the brain tumor are dependent on various factors such as the size, type as well as the exact location of the tumor. These symptoms are triggered when any tumor is pressed or clashed against a nerve or disturbs a part of the brain. Symptoms are also felt when any tumor particle blocks the fluid flowing around the brain or when there is a swelling in the brain owing to the build-up of fluid.

Common symptoms include- headaches that get worse in the morning, nausea along with vomiting, an alteration in the speech, hearing and imbalances in walking and movement, mood swings, change in personality and ability to concentrate or remember things and seizures or convulsions.

Treatment for Brain Tumor-

Surgery is normally the most usual treatment for brain tumors, and the patient is given anaesthesia, and the scalp is shaved before the surgery. Then, craniotomy is performed to open the skull, and the surgeon removes a bone piece out of the skull. Then the tumor is removed as much as possible. The bone is then restored back, and the incision on the scalp is closed. Sometimes surgery is not viable in case the tumor has developed in the brain stem or some other complex parts.

Neurosurgeons can surgically remove some tumors completely (called resection or complete removal). If the tumor is near sensitive areas of the brain, neurosurgeons will only be able to remove part of it (called partial removal). Even partial removals can relieve symptoms and facilitate or increase the effectiveness of other treatments.

The role of surgery in treating brain tumors

Surgery can provide:

- The complete removal of some brain tumors
- A sample to enable doctors to diagnosis the tumor and recommend the most appropriate treatment
- Better quality of life:
- Reduced symptoms and improved ability to function (e.g., to think, speak or see better)
- Less pressure within the skull from the tumor
- A longer life

In case you or any of your near ones is affected with brain tumor, you should visit the doctor to know the possible treatments other than surgery and other important questions related to brain tumor.

Brain Tumor - Causes, Symptoms and Treatment

If you have noticed your child to be restless and anxious all the time, it might look cute as the child is highly energetic, but it could be a cause for concern at the same time. It is not normal and the child could be having ADHD that is attention deficit hyperactivity disorder. As the name suggests, it is a disorder with deficiency of attention and in which the child is always hyperactive.

ADHD is a disorder in which the symptoms usually show up before the age of seven. It is characterized by a group of behavioral symptoms that include inattentiveness, hyperactivity and impulsiveness. The impact of these symptoms is felt extensively where his overall self-esteem is affected, be it at home, preschool or school, academics or extracurricular activities and in interpersonal relationships.

The most common symptoms, which are almost diagnostic of ADHD are:

Inability to hold attention: The child's attention span is very short and it is very difficult to keep them engaged on one particular thing.
Increased restlessness: The child would be extremely restless and gets distracted easily.
Fidgeting: The child would be seen constantly fidgeting with his fingers.
The following are the less common ones:

Learning disability is rare, but can happen. However, the good news is that it does not affect the child's intelligence.
Sleep disorders
Difficulty in following directions
Poor executive functioning skills
Disorganization, which can lead to poor motor coordination and impaired movements
ADHD kids tend to forget things very easily and need help with coordinating movements
The child suffering from ADHD could easily tire and/or feel lethargic with very low energy levels. This can lead to the child procrastinating things and not wanting to do things on priority basis
These children also have difficulties with fine motor and cognitive skills and so there is delay in their overall participation in games.
While these are the pressing symptoms of ADHD, occupational therapy can play a significant role in managing the child in the following ways. As a first step, the caregiver should have a detailed discussion with the school staff and any other people with whom the child interacts significantly.

This will help identify areas that need support from an Occupational Therapy, which are the following:

Support with gross and/or fine motor skills
Support with improving handwriting
Support with engaging in playing sports and games
Support in engaging in social activities
Improving sensory processing difficulties
Improving visual perception
Support in adapting to the environment
Teaching strategies to participate in various social and academic activities
So, while an ADHD child is definitely a cause for concern, proper support from family can help manage the condition.

ADHD - Know The Symptoms

June is known as the Brain Tumour Month worldwide. It s worthwhile to raise public awareness and educate people about brain tumour, a disease which, though is rare is but can be really deadly. More than 500 new cases are diagnosed with brain tumour every day worldwide. The number of patients with secondary tumours are even higher than 500. However, it is common across all ages.  A primary brain tumour is a tumour that begins in the brain. It can be either malignant, which means it contains cancer cells or benign i.e. does not contain cancer cells. A secondary or metastatic brain tumour is usually cancerous. It starts elsewhere in the body and sends cancerous cells which grow in the brain.

Here are a few facts that each one of us should know about this dangerous disease

Brain tumours can occur at any age.
We don t know what causes brain tumors. Family history and high dose radiation like X-rays increases your risk.
Doctors group brain tumors by grade which means the way the brain cells look under a microscope. A higher grade number means the cells appear more abnormal and the more aggressively the tumour usually behaves.
Brain tumors are graded as grade I, grade II, or grade III, or grade IV.
Symptoms
The symptoms of brain tumour depend on the size, type, and location of the brain tumour. Some common symptoms which should not be ignored are-

Headaches
Seizures
Problems with vision
Vomiting
Mental and personality changes
Balance problems and trouble walking
Problems in speaking
Diagnosis
Brain tumours are diagnosed by the doctor based on the medical history and physical examination along with a slew of specialized tests of the brain and nervous system.

Treatment

Surgery
Radiation therapy
Chemotherapy
Anti-seizure medicines
Steroids
Ventricular peritoneal shunt
Combination of treatments
How can you safeguard yourself?
The primary tool to prevent brain tumours is by controlling your lifestyle. This means eating healthy, exercising, avoiding known carcinogens in your environment, and reducing stress.

Sleep: Sleep is a friend for brain health. An adequate amount of rest with eyes shut keeps your brain health.
Frankincense oil: Along with yoga, meditation, and breathing exercises to reduce stress, inhaling frankincense oil can help alleviate inflammation in the brain.
Anti cancer diet: Consuming a diet rich in cancer-fighting nutrients like antioxidants is critical in preventing brain tumors.
Ketogenic diet: A ketogenic diet is a high protein diet. It reduces oxidative stress and inflammation in the brain which is associated with brain tumours. It also shuts down the nutrient supply to tumors.
Calorie restriction: Dietary restriction, especially fasting has anti-carcinogenic properties just as the ketogenic diet.
Limit exposure to mobile phones: Cell phones use increases risk for brain tumours. So restriction prevents these tumours.

World Brain Tumor Day - 6 Tips To Help You Prevent Yourself Against It!

Although surgery is considered to be the first step of treatment in any form of tumor, but its feasibility depends upon the type, size and location of the tumor. It is not necessary that every kind of brain tumor might require surgery.

Indications of Brain Tumor Surgery
- Diagnosis of the type of tumor by taking a sample of the tumor for laboratory examination
- Complete resection of tumor
- Removal of the tumor as much as possible to slow down its growth and improve the symptoms
- Remove the tumor in order to help other treatment
- Provide direct access for other forms of treatment like chemotherapy, radiotherapy etc.
- To relieve pressure caused by tumor on surrounding structures

Types of Brain Tumor Surgery
The different types of surgery that are performed in cases of brain tumor include the following:

Craniotomy: Craniotomy is the most commonly performed procedure to remove brain tumor along with a piece of bone. The removed bone is replaced and the tumor is sent for histopathology (biopsy). The surgery is performed using a high end microscope by any of the following techniques:
- Extended bifrontal craniotomy
- "Eyebrow" craniotomy (supraorbital craniotomy)
- "Keyhole" craniotomy (retro-sigmoid craniotomy)
- Orbitozygomatic craniotomy
- Translabyrinthine craniotomy

Shunt: A narrow piece of flexible tube with a pressure regulated valve in between is called a shunt. This is used to relieve the intracranial pressure caused by obstruction of the natural brain fluid, Cerebrospinal fluid (CSF) pathway by tumor mass. The procedure involves insertion of a drainage system into the brain to remove or drain excess of blocked fluid into the peritoneal cavity.

Stereotactic surgery: This surgery is done by creating a three dimensional image called stereotaxy using computers. It aims to find out the location and position of the tumor. In fact it can also be done to aid tumor removal, implant radiation pellets or for other treatments.

Embolization: It is a procedure used to reduce the amount of blood supply to a tumor by blocking the blood flow in the selected arteries. It is generally performed before the main surgery.

Endoscopy and endoscope assisted surgery: Endoscope is a tool, which helps to closely visualize the tissue through small openings in difficult to reach areas. This tool can be used in various brain surgeries to precisely reach the target location without damaging the adjacent structures.

Adjuvant modalities to improve outcome: In addition to above mentioned surgeries, following surgeries may also be performed in relation to brain tumor treatment:
- Laser surgery
- Photodynamic laser surgery
- Ultrasonic aspiration
- Fluorescence guided surgery (FGS)
- Electrophysiological monitoring

Brain Tumor Surgery

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