The world celebrates world blood donor day on the 14th of june to raise awareness of the need for safe blood and blood products and to thank voluntary and unpaid blood donors for their life-saving gift of blood. 

Importance of blood donation

The importance of donating blood is not only to save the lives of thousands of people who are deprived of life but also to save the lives of many more who are affected by the various diseases. ;

 

It has also been seen that when people; e have donated their blood, they have gained many health benefits as it helps in weight loss, helps maintain healthy liver and iron levels, it helps reduce the risk of heart attack and cancer. ;

 

A blood donation can save a life of- ;


	
	Victims of natural disasters, including earthquakes
	
	
	Patients with hemophilia, sickle cell disease, or cancer
	
	
	People who suffer traumatic injuries from being in a car accident
	
	
	Surgery patients
	
	
	Shooting or stabbing victims
	
	
	Women who suffer complications during childbirth
	


 

Blood types that are needed most

It s good to donate if you re healthy. However, there s always a need for specific blood and plasma which are universal and can be used when a patient blood type is unknown. For newborn infants or if a patient's particular blood type is unavailable.

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	Type o negative blood is always needed because it can be used in patients regardless of their blood type.
	
	
	Type ab positive plasma can also be transfused to patients with other blood types. 
	


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Donations are constantly needed

Because of their short shelf life of 5 days after being collected, platelet donations are constantly by the blood blank. Red blood cells also have a short shelf life and needed to be used within 42 days after the collection. Cryoprecipitate and plasma can be frozen and stored for up to a year after donation.


 

Some misconceptions about blood donations


	
	The donor will not experience any kind of pain while donating. ;
	
	
	There will be no scarcity of blood in the body after donating the blood as even after the donation the body will have a surplus quantity of blood. 
	
	
	The common misconception everyone has is that they will faint after donating their blood. ;
	
	
	You will be able to resume your everyday activity immediately after donating the blood. 
	
	
	You will not get infected with aids if you donate your blood. ;
	


 

Donating blood is a great way to give back to your community and potentially save a life by only giving up an hour of your time.

World Blood Donor Day: How Can We Save Life By Donating Blood?

As the name suggests, kidney cancer, also known as renal cancer, starts in the kidneys. It occurs when the healthy kidney cells grow out of control and become malignant to form cancerous tumours. ;Renal cell carcinoma is the most common type of cancer affecting the kidneys  here cancer begins in the lining of the tubes of your kidney.

Risk factors of kidney cancer

The exact cause of kidney cancer is not known. However, studies suggest that certain factors can make you susceptible to renal cancer. These include  


	
	Smoking
	
	
	Overuse of certain medications
	
	
	Excessive body weight
	
	
	Genes/heredity
	
	
	Gender   men rather than women are prone to kidney cancer
	
	
	An underlying health condition, such as ;high blood pressure
	


Early signs of kidney cancer

The symptoms of renal or kidney cancer depend on its types. In most cases, the disease does not exhibit noticeable symptoms in its early stages. This makes the diagnosis of cancer difficult. However, the signs become more apparent and observable as cancer starts to metastasize. You should watch out for these signs of kidney cancer -


	
	Bouts of blood in the urine   a condition commonly known as haematuria
	
	
	Pain on one side of the lower back (near the kidneys)
	
	
	A lump or mass on the lower back or side, where your kidneys are located
	
	
	Loss of appetite
	
	
	Tiredness or ;fatigue
	
	
	Unintentional weight loss
	
	
	Fever ;that does not cure in days
	
	
	Anaemia   low count of the red blood cells
	
	
	In men, a cluster of enlarged veins called varicocele may develop around the testicles (particularly around the right testicle), indicating the presence of a large tumour
	


Often, these symptoms are mistaken for those of other conditions or diseases. Therefore, it is important to consult a specialist.

If you encounter the above symptoms, or if you are concerned about any changes that you have been experiencing lately, talk to your healthcare provider. A doctor will enquire about the symptoms and might ask you questions related to these signs   how long have you been experiencing them, or how severe is the pain etc. This is crucial for early diagnosis and treatment of kidney cancer.

Know How To Detect Kidney Cancer Early

Your body needs some cholesterol to produce hormones and vitamins that help in digestion. Two types of lipoproteins   ldl cholesterol and hdl cholesterol   are responsible for carrying cholesterol to and from the cells in your body.

Hdl or high-density cholesterol is good cholesterol. It carries bad cholesterol away from the arteries and other body parts back to the liver to be processed by the liver.

Ldl or low-density cholesterol, also known as the bad cholesterol, contributes to fatty build-ups within the arteries. This results in narrowing of the arteries and increases your risk of cardiovascular diseases like pad, heart attack, or even stroke.

Although there are medications to bring down ldl cholesterol levels, your doctor may recommend using therapeutic lifestyle changes to see how well your cholesterol levels can be managed without medications.

How to reduce  bad  cholesterol naturally

You can lower ldl cholesterol levels naturally with the following measures  

Diet and weight loss

Being obese or overweight not only increases the odds of developing high ldl levels but also contributes to cardiac diseases and chronic conditions. Studies suggest that losing even a little weight may help reduce ldl levels.

Your diet plays an important role in losing excess fat and maintaining ideal body weight. Eating the right kind of food   such as those that contain a good amount of monosaturated fats, phytosterols and soluble fibre   can help lower harmful ldl cholesterol and increase the levels of hdl cholesterol in the blood. Focus on eating whole grains, fruits and leafy vegetables, legumes, nuts and seeds, and fatty fish.

Exercise more often

Exercising regularly, in moderate amounts, can bring down your cholesterol levels and promote weight loss. Any form of cardiovascular activity, such as cycling, running, swimming and jogging benefits your heart health. You may also turn to other forms of exercise   weight training or yoga   as they also work to decrease the levels of bad cholesterol.

Quit smoking

Smoking causes a number of chemical changes in your body. Cigarette smoke increases bad cholesterol (ldl) and triglycerides levels. This leads to the accumulation of waxy plaque, which clogs the arteries. At the same time, smoking reduces the level of good cholesterol   the one that prevents the formation of plaque in your blood. Quit smoking and turn to a healthier lifestyle to see a difference in the levels of your ldl cholesterol.

Limit alcohol consumption

According to studies, heavy alcohol consumption or drinking more than what is considered moderate significantly increases bad cholesterol, which again raises triglyceride levels and ldl cholesterol.

Lifestyle changes are the natural and first line of treatment for people with high cholesterol levels. However, if your doctor suspects these levels could put you at risk of other medical conditions, he/she might recommend medications to manage bad cholesterol.

Reduce LDL Cholesterol With These Easy Steps

What are the different types of sickle cell disease?

Sickle cell disease or sickle cell disorder is a term often used to talk about a group of diseases affecting hemoglobin. It is the oxygen-carrying element of blood that makes up 2 alpha globins and 2 beta globins. Sickle cell disease happens due to beta-globin mutation and depending on the abnormality in mutation.

Types-
Sickle cell diseases can be of many types depending on the gene mutation in the blood. Some of the common types are-

Sickle hemoglobin s disease (ss)
Hemoglobin ss disease or sickle cell anemia is the most popular type of scd. It takes place when hemoglobin s gene mutation is inherited from both mother and father. In simple words, it happens when the child inherits one substitution beta-globin gene from each parent. In this type, the body only produces hemoglobin s. It is mostly found in people of african and indian origin.

Sickle hemoglobin- c disease (sc):
Patients with sickle hemoglobin sc disease have a moderately dissimilar swapping in their genes of beta-globin. Here, both hemoglobin c and hemoglobin s are inherited from each parent. It may cause similar symptoms like anemia but remains relatively l. People of west african and mediterranean origin are more prone to this.

Hbs beta-thalassemia
People with this type of scd inherit one sickle cell gene s and one gene for beta-thalassemia from each parent. Zero and plus are the two common types of beta-thalassemia. While beta 0 thalassemia usually takes a severe form, beta + thalassemia is a milder form of the disease.

Sickle beta-zero thalassemia
Beta-zero thalassemia takes form when the child inherits the beta s gene from one parent and beta 0 thalassemia gene mutation from the other. With similar symptoms to anemia, it is a slightly severe form of beta-thalassemia.

Sickle beta-plus thalassemia
Substitutions in both beta-globin genes take place in patients with sickle beta thalassemia (sb) disease. This may even lead to the requirement of blood transfusion if no normal beta globin is produced. Mediterranean and caribbean people are more likely to have this disorder.

Hemoglobin sd, hemoglobin se, and hemoglobin so
These are the few rare and not less common types of sickle cell diseases. They are also less severe. People with these forms of scd inherit one sickle cell gene s and one gene from uncommon hemoglobin (d, e, or o) from each parent.

Sickle cell trait
Hbas
People with sct have one sickle cell gene s and one normal gene a from both mother and father. Ones with this disorder show few to no signs of the disease and usually spend a normal life. However, the risk to their future generations still exists.
 

What Are The Different Types Of Sickle Cell Disease?

People with sickle cell disease often experience myriad symptoms of the disease that can be controlled by the right nutrition. Reports suggest that nutrition is an increasingly significant factor to prevent symptoms such as slow growth, lower body mass, joint issues, infections, pain crises, and anemia.

There is a greater than the typical requirement for both calories and micronutrients.

The nutritional requirement of a sickle cell patient emphasizes more on vegetables, fruits, whole grains, and more similar food items. These can prevent any deficiencies in the body and also decrease any chances of disease exacerbation.

 


	
	High-calorie nutrient-dense diet
	


The usual energy intake in a sickle cell patient is normally lower than the average values. It is a case even when the condition is asymptomatic where the requirement drops to half the level. As a result, people with sickle cell diseases (especially kids) are at higher risk for impaired growth and considerably lesser fat and fat-free mass, with obesity also posing a risk. It is suggested to have adequate energy supplements in the diet to reach the minimum sufficient requirement of the body that can be done only by proper nutritional assessment.


	
	Adequate fluids
	


Avoiding dehydration is another significant factor to avoid any severe symptoms of sickle cell disease. Sickling of the erythrocytes aggravates in patients who perform hardcore physical work in the heat without drinking enough fluids. This leads to dehydration and can even result in constipation.


	
	Micronutrients
	


Micronutrient deficiencies can be found in sickle cell patients up to a great extent. Several vitamins and minerals like vitamin a, b6, c, e, carotenoids, zinc, and magnesium are often found in fewer numbers in scd patients. A significant drop in blood-antioxidant status may result in acute chest syndrome. The supplementation of these vitamins and minerals can reduce the number of sickled cells in the body. Plant phenols and flavonoids may also help in lowering oxidative stress.


	
	Calcium-rich food
	


Getting plenty of calcium-rich food like dairy products, leafy vegetables, cereals, and fruit juices aids the child's growth and development. This may lead to a stronger physical structure and a greater resistance to the disease.


	
	Omega-3 fatty acid
	


There are reduced proportions of omega-3 polyunsaturated fatty acids in sickle cell patients. These acids aid the fluidity of red blood cell membranes. As a result, they prevent sickle cell crises. Supplemental docosahexaenoic (dha) and eicosapentaenoic (epa) have shown numerous therapeutic benefits in scd patients.


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Role Of Nutrition In Sickle Cell Disease

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