World sickle cell day is observed annually on the 19th of june to raise awareness of sickle cell-related diseases. It is observed to increase people's knowledge and the understanding required to face the challenges posed by the disease.


 

What is sickle cell disorder (scd)?

Sickle cell disorders or sickle cell diseases are genetic blood disorders that cause an abnormality in the red blood cells. The rbcs turn into sickle-shaped cells that stick together and block the blood flow in the body.


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Types

There are four major classifications of sickle cell diseases-


	
	Hemoglobin ss disease
	
	
	Hemoglobin sc disease
	
	
	Hemoglobin sb+ thalassemia
	
	
	Hemoglobin sb 0 thalassemia
	



 

Symptoms

One can start noticing symptoms of sickle cell in a patient at around 6 years of age. However, they can differ from person to person. Some of the most typical symptoms are-

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	Anemia
	


A shortage of red blood cells occurs due to the excessive early dying in 10-20 days. It leads to an oxygen shortage in the body.


	
	Excessive pain
	


Blockage of blood flow due to the change in shape leads to periodic cycles of pain in the body.


	
	Swelling in the body
	


As the blood circulation becomes irregular, swelling becomes a regular phenomenon.


	
	Infections
	


Sickle cell can be damaging to the spleen. It increases the risk of ailments in the body that can be prevented only by antibiotics.


	
	Delayed puberty
	


Oxygen and nutrients carried by the blood are required for growth. As a reason, irregular blood flow can lead to slow growth or delay in puberty.


	
	Vision issues
	


Infected blood vessels carrying blood to the eyes can cause damage to the retina. It can lead to visual problems.


 

Traits and treatment

As sickle cell is genetic, it is suggested to take a test that can detect any trait of the disease. It can prevent any life-threatening risks to the newborn. However, we don't have a complete cure for sickle cell disorders. There are preventive measures that reduce the adversity of the disease to an extent. Procedures like blood transfusions help greatly in minimizing the effects of the disorder.

World Sickle Cell Day: Know All About Sickle Cell Disease

As the name suggests, kidney cancer, also known as renal cancer, starts in the kidneys. It occurs when the healthy kidney cells grow out of control and become malignant to form cancerous tumours. ;Renal cell carcinoma is the most common type of cancer affecting the kidneys  here cancer begins in the lining of the tubes of your kidney.

Risk factors of kidney cancer

The exact cause of kidney cancer is not known. However, studies suggest that certain factors can make you susceptible to renal cancer. These include  


	
	Smoking
	
	
	Overuse of certain medications
	
	
	Excessive body weight
	
	
	Genes/heredity
	
	
	Gender   men rather than women are prone to kidney cancer
	
	
	An underlying health condition, such as ;high blood pressure
	


Early signs of kidney cancer

The symptoms of renal or kidney cancer depend on its types. In most cases, the disease does not exhibit noticeable symptoms in its early stages. This makes the diagnosis of cancer difficult. However, the signs become more apparent and observable as cancer starts to metastasize. You should watch out for these signs of kidney cancer -


	
	Bouts of blood in the urine   a condition commonly known as haematuria
	
	
	Pain on one side of the lower back (near the kidneys)
	
	
	A lump or mass on the lower back or side, where your kidneys are located
	
	
	Loss of appetite
	
	
	Tiredness or ;fatigue
	
	
	Unintentional weight loss
	
	
	Fever ;that does not cure in days
	
	
	Anaemia   low count of the red blood cells
	
	
	In men, a cluster of enlarged veins called varicocele may develop around the testicles (particularly around the right testicle), indicating the presence of a large tumour
	


Often, these symptoms are mistaken for those of other conditions or diseases. Therefore, it is important to consult a specialist.

If you encounter the above symptoms, or if you are concerned about any changes that you have been experiencing lately, talk to your healthcare provider. A doctor will enquire about the symptoms and might ask you questions related to these signs   how long have you been experiencing them, or how severe is the pain etc. This is crucial for early diagnosis and treatment of kidney cancer.

Know How To Detect Kidney Cancer Early

When abnormal cells grow inside the brain and are in the form of a mass the condition is called a brain tumour. However, on the other hand, brain cancer is a disease of the brain in which cancer cells (malignant cells) arise in the brain tissue. Cancer cells grow to form a mass of cancer tissue (tumour) that interferes with brain functions such as muscle control, sensation, memory, and other normal body functions. 

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Some brain tumours are cancerous while others fall under the category of non-cancerous ones.

Brain cancer is actually the abnormal growth and uncontrolled growth of the cancer cells in the brain, that forms a tumour in the brain. Tumours can be either benign or malignant.

Benign brain tumours are abnormal collections of cells that reproduce slowly and usually remain separate from the surrounding normal brain.

Malignant tumours reproduce and grow quickly. Their borders are hard to distinguish from the normal brain around them.

 

The underlying cause of primary brain cancer, cancer that begins in the brain, is not known. Secondary brain cancer is caused by a cancer of another organ in the body, such as the breast, prostate, kidney, skin, or bone, that has spread to the brain.

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The brain tumours originate in the brain itself. Tumours start to develop if there are mutations in the dna. It is because of these mutations that cells of the brain increasingly grow and divide. Usually, in adults, the primary brain tumours are uncommon in comparison to the secondary brain tumours.


 

There are few early symptoms of brain cancer, but as the tumour grows within the confines of the skull, it causes increased intracranial pressure and exerts pressure on the brain, causing signs to develop.


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Brain cancer occurs when there is an uncontrolled growth of cancer cells in the brain that form a malignant brain tumour. The underlying cause of primary brain cancer, cancer that begins in the brain, is not known. Secondary brain cancer is caused by a cancer of another organ in the body, such as the breast, prostate, kidney, skin, or bone, that has spread to the brain.


 

What Is The Significant Difference Between Brain Tumour And Brain Cancer?

Cervical cancer is a ;cancer that affects the cells of the cervix in women. The cancer is believed to be caused by exposure to human papilloma virus (hpv). Also, there are certain factors that are linked to an increased risk of acquiring hpv and developing cervical cancer.

What Are The Major Risk Factors Of Cervical Cancer?

C-reactive protein ;is a type of protein produced by the liver in response to an infection ;or inflammation. When your body contracts an infection, the white blood cells produce proteins to fight it. Some of these proteins activate the liver into producing c-reactive protein. For many years, the crp ;blood level has been used to ascertain the level of infection or inflammation.

Assessing the risk of heart disease ;with c-reactive protein

The level of crp is a potential indicator of how likely you are to develop cardiovascular diseases. This is because the development of atherosclerosis is linked with inflammation within the walls of your blood vessel. This results in higher levels of c-reactive protein in atherosclerosis patients than in those without the disorder.

The greater the crp levels, the more chances you have of being affected by cardiovascular disorders. The test also determines the risk of a second attack.

The value of knowing your crp levels depends on whether you come under one of three cardiovascular risk groups.


	
	High risk   not important to know crp because you should be combining lifestyle changes and aggressive treatment to reduce risk
	
	
	Intermediate risk   helpful to find out crp levels, as it can provide vital information crucial in deciding the next line of treatment
	
	
	Low risk   even if your crp levels are high, you will not be at risk   due to negligible risk factors and low cholesterol levels   that should require more than just lifestyle changes
	


To find out crp levels you will have to take a blood test. C-reactive protein is classified into  


	
	High   equal to or greater than 3
	
	
	Intermediate   between 1 and 3
	
	
	Low   below 1
	


If you are having a c-reactive protein test to check for heart diseases, your healthcare provider may recommend a cholesterol test as well. A number of other tests may also be prescribed to evaluate your risk further.

How C-reactive Protein Can Pose A Risk For Heart Disease?

A brain tumour is a life-threatening situation. Most of the symptoms of the brain tumour are alike, but not all tumours are malignant. The most common type of brain tumour is meningioma. You may even don t need surgery in this case as they are really not dangerous or life-threatening.

 

Here are some of the facts you should know about meningioma:

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Meningioma can develop in numerous locations

 

Cells in the meninges, the lining of the brain and spinal cord, give rise to these tumours. In fact, they are not brain tumours at all, because they are not caused by the altered brain cells. ;

However, they continue to grow inside your sull, indicating that you should now take immediate steps. Meningioma can produce brain tumour symptoms if it grows or creates swelling that presses against the brain or other tissues in the skull.

 

Meningioma symptoms vary depending on the size and location of the tumour

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Meningioma can cause vision-related issues, headaches or seizures which are all common signs of a brain tumour. A headache, even a strong one, is seldom an indication of meningioma or any other type of brain tumour on its own. 

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Other tumour sites can influence your sense of smell, vision, hearing and even the pituitary gland s function.

 

Meningioma diagnosis usually happens when the doctor is looking for some else

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The discovery of a tumour on a ct scan or mri while investigating the patient for another cause, such as a head injury or another neurological condition, is called an accidental diagnosis. When a doctor identifies a meningioma, you will undergo additional testing to determine how the tumour will behave. A neurosurgeon will decide whether to remove the tumour or just monitor it to see whether it grows based on these findings. 

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Majority of meningioma does not spread

 

Being diagnosed with meningioma, especially a large one, might be shocking, but these tumours are usually non-dangerous. Tumour cells are unlikely to spread to other sections of the body as a result of this. ;

Meningiomas, on the other hand, can grow silently for years without creating any difficulties and they can grow to be enormous.

 

Things You Should Know About Most Common Brain Tumours

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